Menée auprès de 15 550 femmes à risque héréditaire de cancer du sein (âge : 18-79 ans ; durée médiane de suivi : 10,3 ans), cette étude analyse l'association entre la période de pratique d'une activité physique de loisir et le risque de développer la maladie (896 cas)

Recreational physical activity is associated with reduced breast cancer risk in adult women at high risk for breast cancer: a cohort study of women selected for familial and genetic risk

Kehm, Rebecca D ; Genkinger, Jeanine M ; MacInnis, Robert J ; John, Esther M. ; Phillips, Kelly-Anne ; Dite, Gillian S. ; Milne, Roger L. ; Zeinomar, Nur ; Liao, Yuyan ; Knight, Julia A. ; Southey, Melissa C. ; Chung, Wendy K. ; Giles, Graham G. ; McLachlan, Sue-Anne ; Whitaker, Kristen D ; Friedlander, Michael ; Weideman, Prue C ; Glendon, Gord ; Nesci, Stephanie ; Investigators, kConFab ; Andrulis, Irene L. ; Buys, Saundra S. ; Daly, Mary B. ; Hopper, John L. ; Terry, Mary Beth

While physical activity is associated with lower breast cancer risk for average-risk women, it is not known if this association applies to women at high familial/genetic risk. We examined the association of recreational physical activity (self-reported by questionnaire) with breast cancer risk using the Prospective Family Study Cohort (ProF-SC), which is enriched with women who have a breast cancer family history (N=15,550). We examined associations of adult and adolescent recreational physical [...]

A partir d'une revue de la littérature publiée jusqu'en juin 2018 (16 études), cette méta-analyse évalue l'association entre une consommation de fibres alimentaires et le risque de cancer de l'endomètre

Association between dietary fiber and endometrial cancer: a meta-analysis

Li, Hengjie ; Mao, Hui ; Yu, Yi ; Nan, Yong

To explore a potential relationship between dietary fiber consumption and risk of endometrial cancer (EC), eligible studies published up to 30 June 2018 were retrieved via computer searches and manual review of references. Random-effects models were used to calculate summary relative risk (RR) estimates based on contrasting high- and low-fiber intake values. Sensitivity analysis was conducted, and heterogeneity among study results was explored through stratified analyses by study design, [...]

Menée en Suède sur la période 2005-2015 auprès d'une cohorte de 544 130 personnes diabétiques et d'une cohorte témoin de 4 525 543 individus (durée médiane de suivi : 5,8 ans), cette étude analyse l'association entre une utilisation de la metformine et le risque d'adénocarcinome gastrique (7 287 cas)

Metformin use and risk of gastric adenocarcinoma in a Swedish population-based cohort study

Zheng, Jiaojiao ; Xie, Shao-Hua ; Santoni, Giola ; Lagergren, Jesper

Background : Whether or not the use of metformin decreases the risk of gastric adenocarcinoma is unclear. Methods : This was a population-based cohort study in 2005–2015. Associations between metformin use and gastric non-cardia and cardia adenocarcinomas were examined within two cohorts; a diabetes cohort of participants using anti-diabetes medications, and a matched cohort of common-medication users, where metformin non-users were frequency matched (10:1) with metformin users for sex and age. [...]

Menée en Angleterre dans 131 lieux de soins et 131 établissements d'enseignement supérieur, cette étude compare les politiques en matière de vapotage et de lutte contre le tabagisme sur le lieu de travail

Policies for tobacco and e-cigarette use: a survey of all higher education institutions and NHS Trusts in England

Blackwell, Anna K M ; Kosīte, Daina ; Marteau, Theresa M ; Munafò, Marcus R

There is an absence of evidence regarding the impact of treating tobacco smoking and vaping equivalently in workplace policies. We aimed to describe and compare smoking and vaping policies in acute non-specialist NHS Trusts (n=131) and Higher Education Institutions (HEIs) (n=131) in England.We conducted a census of smoking and vaping policies through organisational websites searches and direct requests for information. We recorded whether and where smoking and vaping were permitted.Smoking was [...]