Menée en France par enquête transversale auprès de 78 patients atteints d'un cancer digestif (tumeur colorectale, pancréatique et autre), cette étude analyse leurs difficultés sexuelles et leurs besoins en soins de support pendant une chimiothérapie

Sexual health and needs for sexology care in digestive cancer patients undergoing chemotherapy: a 4-month cross-sectional study in a French University Hospital

Almont, Thierry ; Couteau, Corinne ; Etienne, Hélène ; Bondil, Pierre ; Guimbaud, Rosine ; Schover, Leslie ; Huyghe, Éric

Purpose : To assess sexual health and needs for sexology care of cancer patients during chemotherapy. Methods : We performed a 4-month cross-sectional study in cancer patients treated by chemotherapy in the digestive cancer department of a regional university hospital. Patients were asked to fill out a self-administered questionnaire about their sexual health, Sexual Quality of Life Questionnaire for Male (SQoL-M) or Female (SQoL-F), and their needs for sexology care. Results : The study sample [...]

Menée au Canada par enquête auprès de 527 patients ayant survécu à un cancer du poumon, cette étude évalue l'association entre une activité physique, des comportements sédentaires et la qualité de vie

Associations of objectively assessed physical activity and sedentary time with health-related quality of life among lung cancer survivors: A quantile regression approach

D’Silva, Adrijana ; Gardiner, Paul A. ; Boyle, Terry ; Bebb, Gwyn D. ; Johnson, Steven T. ; Vallance, Jeff K.

Objectives : No studies have examined objectively assessed physical activity, sedentary time, and patient-reported outcomes among lung cancer survivors. The objective of this study was to determine associations of objectively assessed moderate-to-vigorous intensity physical activity (MVPA) and sedentary time with health-related quality of life (HRQoL) and fatigue among lung cancer survivors. Materials and method : Lung cancer survivors in Southern Alberta (N = 527) were invited to complete a [...]

Menée auprès de 23 patients atteints d'un cancer primitif du poumon non à petites cellules, cette étude prospective évalue les effets de l'activité physique quotidienne (marche, exercices) avant un traitement chirurgical sur l'état de santé et la qualité de vie, mesurés 1, 3 et 6 mois après l'opération

Physical behavior and associations with health outcomes in operable NSCLC patients: a prospective study

Timmerman, J. G. ; Dekker-van Weering, M. G. H. ; Wouters, M. W. J. M. ; Stuiver, M. M. ; de Kanter, W. ; Vollenbroek-Hutten, M. M. R.

Objectives : Our objectives were to 1) characterize daily physical behavior of operable non-small cell lung cancer (NSCLC) patients, from preoperative to six months postoperative using accelerometry, and explore if physical behavior preoperative or one month postoperative is associated with better health outcomes at six months postoperative. Methods : A prospective study with 23 patients (13 female) diagnosed with primary NSCLC and scheduled for curative lung resection was performed. Outcome [...]

Mené sur 790 patients atteints d'un cancer de la prostate, cet essai évalue l'intérêt, du point de vue de la qualité de vie, de l'ajout du docétaxel à une thérapie anti-androgénique

Quality of Life During Treatment With Chemohormonal Therapy: Analysis of E3805 Chemohormonal Androgen Ablation Randomized Trial in Prostate Cancer

Alicia K. Morgans ; Yu-Hui Chen ; Christopher J. Sweeney ; David F. Jarrard ; Elizabeth R. Plimack ; Benjamin A. Gartrell ; Michael A. Carducci ; Maha Hussain ; Jorge A. Garcia ; David Cella ; Robert S. DiPaola ; Linda J. Patrick-Miller

Purpose : Chemohormonal therapy with docetaxel and androgen deprivation therapy (ADT+D) for metastatic hormone-sensitive prostate cancer improves overall survival as compared with androgen deprivation therapy (ADT) alone. We compared the quality of life (QOL) between patients with metastatic hormone-sensitive prostate cancer who were treated with ADT+D and those who were treated with ADT alone. Methods : Men were randomly assigned to ADT+ D (six cycles) or to ADT alone. QOL was assessed by [...]

A partir des données des registres américains des cancers portant sur la période 2004-2013, cette étude évalue l'effet du statut socioéconomique sur la survie, chez des patients atteints d'un carcinome épidermoïde de l'anus (9 550 cas , âge médian : 58 ans)

Impact of socioeconomic status on survival for patients with anal cancer

Lin, Daniel ; Gold, Heather T. ; Schreiber, David ; Leichman, Lawrence P. ; Sherman, Scott E. ; Becker, Daniel J.

BACKGROUND: Although outcomes for patients with squamous cell carcinoma of the anus (SCCA) have improved, the gains in benefit may not be shared uniformly among patients of disparate socioeconomic status. In the current study, the authors investigated whether area-based median household income (MHI) is predictive of survival among patients with SCCA. METHODS: Patients diagnosed with SCCA from 2004 through 2013 in the Surveillance, Epidemiology, and End Results registry were included. [...]

A partir des données des registres américains des cancers portant sur 5 975 patients atteints d'un cancer du pancréas sur la période 1998-2009, cette étude analyse l'association entre les traitements reçus par les patients âgés entre 66 et 74 ans et la survie

Evaluation of Treatment Patterns and Survival Outcomes in Elderly Pancreatic Cancer Patients: A Surveillance, Epidemiology, and End Results-Medicare Analysis

Shaib, Walid L. ; Jones, Jeb S. ; Goodman, Michael ; Sarmiento, Juan M. ; Maithel, Shishir K. ; Cardona, Kenneth ; Kane, Sujata ; Wu, Christina ; Alese, Olatunji B. ; El‐Rayes, Bassel F.

Background : Management of pancreatic cancer (PC) in elderly patients is unknown; clinical trials exclude patients with comorbidities and those of extreme age. This study evaluated treatment patterns and survival outcomes in elderly PC patients using linked Surveillance, Epidemiology, and End Results (SEER) and Medicare data. Materials and Methods : Histology codes 8140, 8500, 8010, 8560, 8490, 8000, 8260, 8255, 8261, 8263, 8020, 8050, 8141, 8144, 8210, 8211, or 8262 in Medicare Parts A and B [...]

A partir d'une revue systématique de la littérature (67 articles), cette étude analyse la présence et les caractéristiques des troubles psychiques, ainsi que les facteurs associés, chez des patients ayant survécu à un cancer diagnostiqué pendant l'enfance ou en début de vie adulte

Mental health of long-term survivors of childhood and young adult cancer: A systematic review

Friend, Amanda J. ; Feltbower, Richard G. ; Hughes, Emily J. ; Dye, Kristian P. ; Glaser, Adam W.

Childhood cancer is increasing in prevalence whilst survival rates are improving. The prevalence of adult survivors of childhood cancer is consequently increasing. Many survivors suffer long-term consequences of their cancer treatment. Whilst many of these are well documented, relatively little is known about the mental health of survivors of childhood cancer. This article aimed to describe the prevalence and spectrum of mental health problems found in adult survivors of childhood cancer using [...]

Menée aux Etats-Unis auprès de 547 patients ayant survécu à un cancer, cette étude analyse l'association entre leurs difficultés financières, leurs inquiétudes concernant l'accès aux soins, leur façon de gérer l'expérience de la maladie et leur capacité à faire des changements positifs dans leur vie

Financial difficulty, worry about affording care, and benefit finding in long-term survivors of cancer

Jones, Salene M. W. ; Walker, Rod ; Fujii, Monica ; Nekhlyudov, Larissa ; Rabin, Borsika A. ; Chubak, Jessica

Objective: To examine the associations of worry about affording care and reporting financial difficulties with benefit finding in long-term cancer survivors. Methods: Long-term survivors of cancer (n = 547) in 3 integrated health care delivery systems completed the Medical Expenditure Panel Survey Cancer Survivorship Supplement. The relationship between benefit finding (becoming a stronger person, coping better, and making positive changes) and the potentially interacting factors of worry about [...]

Menée en Australie par enquête auprès de 152 patientes atteintes d'un cancer du sein, cette étude analyse les facteurs associés aux difficultés rencontrées dans leur vie sentimentale et affective

Factors associated with romantic relationship formation difficulties in women with breast cancer

Shaw, L. K. ; Sherman, K. A. ; Fitness, J. ; Elder, E. ; Breast Cancer Network, Australia

Objective: Many un-partnered women report difficulty in forming romantic relationships after breast cancer, characterized by high dating-related anxiety and low perceived interpersonal competence. This study examined the relationship between poor body image (appearance investment and body dissatisfaction) and self-compassion, and women's ability to form romantic relationships post-breast cancer. Methods: Women (N = 152) diagnosed with breast cancer, who were either un-partnered and expressed [...]

Menée dans un contexte américain, cette étude analyse le rappport coût-efficacité de l'alectinib pour prévenir le développement de métastases cérébrales chez des patients atteints d'un cancer du poumon non à petites cellules ALK+

Economic impact of preventing brain metastases with alectinib in ALK-positive non-small cell lung cancer

Burudpakdee, C. ; Wong, W. ; Seetasith, A. ; Corvino, F. A. ; Yeh, W. ; Gubens, M.

Objectives : Despite improved progression-free survival, most patients treated with the first generation ALK inhibitor crizotinib, ultimately experience central nervous system (CNS) progression. Brain metastases (BM) are associated with high clinical burden in patients with advanced anaplastic lymphoma kinase positive (ALK+) non-small cell lung cancer (NSCLC). In this study we estimate the real-world economic burden of BM in newly diagnosed ALK+ NSCLC patients and investigate whether alectinib, [...]

Menée en Australie auprès de 37 patientes atteintes d'un cancer du sein et devant recevoir une radiothérapie, cette étude analyse l'efficacité d'un outil pédagogique utilisant la réalité virtuelle pour améliorer leurs connaissances relatives à la radiothérapie et réduire leurs symptômes d'anxiété

Patient education using virtual reality increases knowledge and positive experience for breast cancer patients undergoing radiation therapy

Jimenez, Yobelli A. ; Cumming, Steven ; Wang, Wei ; Stuart, Kirsty ; Thwaites, David I. ; Lewis, Sarah J.

Purpose : Improved access to technology in the radiation therapy (RT) workforce education has resulted in opportunities for innovative patient education methods. This study investigated the impact of a newly developed education tool using the Virtual Environment for Radiotherapy Training (VERT) system on patients’ RT knowledge and anxiety. Method : Breast cancer patients were recruited into a control group (CG) (n = 18) who underwent the standard pre-RT education package at a targeted cancer [...]

A partir des données des registres américains des cancers portant sur 5 080 patientes atteintes d'un cancer du sein de stade précoce diagnostiqué entre 2013 et 2015 (âge : de 20 à 79 ans), cette étude analyse les pratiques de conseils d'ordre génétique après le diagnostic de la maladie

Gaps in Receipt of Clinically Indicated Genetic Counseling After Diagnosis of Breast Cancer

Steven J. Katz ; Kevin C. Ward ; Ann S. Hamilton ; M. Chandler Mcleod ; Lauren P. Wallner ; Monica Morrow ; Reshma Jagsi ; Sarah T. Hawley ; Allison W. Kurian

Purpose : Little is known about the extent to which genetic counseling is integrated into community practices for patients newly diagnosed with breast cancer. We examined the receipt of clinically indicated genetic counseling in these patients. Patients and Methods : We surveyed 5,080 patients between the ages of 20 and 79 years, diagnosed from July 2013 to August 2015 with early-stage breast cancer and reported to the SEER registries of Georgia and Los Angeles County. Surveys were linked to [...]