Mené en Turquie à partir de données portant sur 90 patients atteints de cancer, cet essai randomisé compare l'efficacité d'une cryothérapie et de bains de bouche à base de chlorhexidine pour réduire et prendre en charge une mucite buccale induite par la chimiothérapie

Comparison of efficacy of cryotherapy and chlorhexidine to oral nutrition transition time in chemotherapy-induced oral mucositis

Erden, Y. ; Ipekcoban, G.

The aim of this study was to compare the efficacy of cryotherapy and chlorhexidine to oral nutrition transition time in chemotherapy-induced oral mucositis. This randomised controlled trial with random assignments to the experimental and control groups was conducted with cancer patients. Study data were collected from 90 cancer patients. The first experimental group (n = 30) received chlorhexidine mouthwash, the second experimental group (n = 30) received oral cryotherapy and the control group [...]

A partir d'une revue systématique de la littérature (7 études, 147 cas), cette étude analyse les facteurs associés aux troubles du sommeil chez des patients pédiatriques hospitalisés pour un cancer (âgés de 1 à 18 ans)

A systematic review of sleep in hospitalized pediatric cancer patients

Lee, Soeun B. A. ; Narendran, Gaya ; Tomfohr-Madsen, Lianne ; Schulte, Fiona

Objective : The purpose of this systematic review was to describe the occurrence of sleep disruptions in pediatric cancer patients and to identify and discuss the factors related to the hospital sleep environment that may be associated with disturbed sleep. Methods : A total of 108 articles were located in five databases (PubMed, PsychINFO, Medline, CancerLit, and Google Scholar), and seven met our inclusion criteria and formed the basis of this review. Results : Participants ranged from 1 to [...]

A partir d'une revue systématique de la littérature (11 articles), cette étude fait le point sur les symptômes de fatigue liée au cancer décrits par des enfants et adolescents (âgés de 6 à 19 ans) et l'impact de cette fatigue sur leur qualité de vie

The lived experience of fatigue in children and adolescents with cancer: a systematic review

Tomlinson, D. ; Zupanec, S. ; Jones, H. ; O’Sullivan, C. ; Hesser, T. ; Sung, L.

Purpose : Objectives of this systematic review were to summarize how fatigue has been described from the perspective of children and adolescents with cancer, the impact of fatigue on quality of life, and child reported contributing factors and potential alleviators of fatigue. Methods : We conducted electronic searches of Ovid Medline, EMBASE, PsycInfo, Science Citation, Social Science Citation (Web of Science), and CINAHL. We included studies of children and adolescents with cancer in which [...]

Menée en Allemagne auprès de 66 patients atteints de cancer et recevant une chimiothérapie à haute dose et une greffe autologue de cellules souches, cette étude évalue l'efficacité d'une musico-thérapie, en complément des soins de supports traditionnels, pour améliorer leur qualité de vie et réduire les symptômes de dépression et d'anxiété

The effects of music therapy in patients with high-dose chemotherapy and stem cell support: a randomized pilot study

Tuinmann, Gert ; Preissler, Pia ; Böhmer, Hauke ; Suling, Anna ; Bokemeyer, Carsten

Objective : Patients with high dose chemotherapy (HDC) with autologous stem cell transplantation (ASCT) are highly distressed. Psycho-oncological support might be beneficial but is not routinely provided. Our aim was to investigate whether music therapy (MT) in addition to standard supportive treatment had any effect on quality of life, depression, anxiety, side effects of therapy, medication, and immunological changes during and within three months after HDC plus ASCT. Methods : Patients [...]

Mené aux Etats-Unis auprès de 79 patients atteints d'un cancer de stade avancé (âge médian : 57 ans), cet essai clinique évalue l'association entre le niveau d'activité quotidienne, la qualité du sommeil et des symptômes liés à la maladie

Association between Daytime Activity, Fatigue, Sleep, Anxiety, Depression, and Symptom Burden in Advanced Cancer Patients: A Preliminary Report

Yennurajalingam, Sriram ; Tayjasanant, Supakarn ; Balachandran, Dave ; Padhye, Nikhil S. ; Williams, Janet L. ; Liu, Diane D. ; Frisbee-Hume, Susan ; Bruera, Eduardo

Background: There is limited research in advanced cancer patients (ACP) regarding association between objectively measured daytime activity and sleep (as measured by actigraphy), patient characteristics, and cancer symptoms (fatigue, sleep, anxiety, depression, cachexia, and symptom distress scores [SDSs]). Objectives: Our aim of the study was to determine the association between mean daytime activity (MDTA) and the following items: fatigue (FACIT-F), SDSs (Edmonton Symptom Assessment Scale [...]

Menée aux Etats-Unis par enquête téléphonique auprès de 71 patients ayant survécu à un cancer du pancréas, cette étude analyse les facteurs empêchant ou facilitant leur participation, peu de temps après le diagnostic, à un programme constitué d'exercices physiques et d'interventions nutritionnelles

Pancreatic cancer survivors’ preferences, barriers, and facilitators related to physical activity and diet interventions

Arthur, Anna E. ; Delk, Ashley ; Demark-Wahnefried, Wendy ; Christein, John D. ; Contreras, Carlo ; Posey, James A. ; Vickers, Selwyn ; Oster, Robert ; Rogers, Laura Q.

Purpose : To conduct a telephone survey establishing pancreatic cancer survivors’ level of interest in, preferences for, and perceived barriers and facilitators to participating in exercise and diet intervention programming. These data will inform the development of such interventions for newly-diagnosed patients. Methods : Seventy-one survivors treated for resectable pancreatic adenocarcinoma from October 2011 to August 2014 were identified through an institutional cancer registry and [...]

A partir d'une revue systématique de la littérature (5 articles), cette étude fait le point sur l'efficacité des thérapies destinées aux couples pour surmonter leurs difficultés sexuelles après un cancer du sein

Couple-based treatment for sexual problems following breast cancer: A review and synthesis of the literature

Carroll, Allison J. ; Baron, Shirley R. ; Carroll, Richard A.

Purpose : Although there are many physical and psychological impacts on women’s sexuality following breast cancer diagnosis and treatment, sexual problems often remain unaddressed in these cancer survivors. Given the crucial role of the partner in sexual issues, couple-based sex therapy would appear to be a logical first-line treatment for this population, but there is scant research on the efficacy of couple-based treatments and/or sex therapy in breast cancer survivors. Methods : A review of [...]

Menée au Danemark auprès de 97 patientes atteintes d'un cancer du sein de stade précoce (âge moyen : 53 ans), cette étude de cohorte prospective évalue les effets d'une chimiothérapie adjuvante sur les changements de densité minérale osseuse, 4 mois après la fin du traitement

Change in bone mineral density during adjuvant chemotherapy for early-stage breast cancer

Christensen, Carina Ørts ; Cronin-Fenton, Deirdre ; Frøslev, Trine ; Hermann, Anne Pernille ; Ewertz, Marianne

Purpose : Adjuvant chemotherapy has been associated with loss of bone mineral density (BMD) either as a direct effect or due to glucocorticoids used as supportive care medication. A prospective cohort study was conducted to evaluate changes in BMD from baseline to right after completion of chemotherapy, i.e., 4 months. Methods : Dual-imaging X-ray absorptiometry (DXA) was performed at baseline and after completing anthracycline- and taxane-based chemotherapy to measure BMD in the spine, hip, [...]

A partir d'une revue systématique de la littérature (4 essais randomisés, 234 patientes), cette méta-analyse évalue l'efficacité d'un drainage lymphatique manuel pour réduire et prendre en charge un lymphœdème lié au cancer du sein

Manual lymphatic drainage for breast cancer-related lymphoedema

Shao, Y. ; Zhong, D. S.

Breast cancer-related lymphoedema (BCRL) is a common sequela of surgical or radiation therapy of breast cancer. Although being an important part of conservative therapy, the role of manual lymphatic drainage (MLD) on BCRL is still debating. The objective of the current systematic review and meta-analysis was to determine whether the addition of MLD to the standard therapy (ST) could manage BCRL more effectively. We searched PubMed, EMBASE and Cochrane Library for related randomised clinical [...]

Menée aux Etats-Unis auprès de 785 cas et 3 323 témoins, cette étude de cohorte analyse les effets à long terme des traitements chez des patients ayant survécu à un cancer du testicule diagnostiqué entre 1991 et 2007 (durée médiane de suivi : 10 ans)

Long-term health effects among testicular cancer survivors

Hashibe, Mia ; Abdelaziz, Sarah ; Al-Temimi, Mohammed ; Fraser, Alison ; Boucher, Kenneth M. ; Smith, Ken ; Lee, Yuan-Chin Amy ; Rowe, Kerry ; Rowley, Braden ; Daurelle, Micky ; Holton, Avery E. ; VanDerslice, James ; Richiardi, Lorenzo ; Bishoff, Jay ; Lowrance, Will ; Stroup, Antoinette

Purpose : Testicular cancer is diagnosed at a young age and survival rates are high; thus, the long-term effects of cancer treatment need to be assessed. Our objectives are to estimate the incidence rates and determinants of late effects in testicular cancer survivors. Methods : We conducted a population-based cohort study of testicular cancer survivors, diagnosed 1991–2007, followed up for a median of 10 years. We identified 785 testicular cancer patients who survived ≥5 years and 3323 men [...]

A partir des données du registre suédois des cancers portant sur la période 1958-2012 et du registre des naissances portant sur la période 1973-2012, cette étude évalue l'association entre traitements reçus par les patientes ayant survécu à un cancer et le risque, pour leur enfant, de décès à la naissance ou avant 28 jours

Stillbirth and neonatal death among female cancer survivors: A national cohort study

Ji, Jianguang ; Sundquist, Jan ; Sundquist, Kristina

The number of cancer survivors continues to increase worldwide. Many of these survivors have had children of their own. It is less well-known whether radiation therapy or chemotherapy could affect the risk of stillbirth and neonatal death for these children. To explore this research questions, we identified all women diagnosed with cancer between 1958 and 2012 from the Swedish Cancer Register and they were further linked to the Swedish Medical Birth Register to identify their subsequent child [...]

A partir des données de 9 registres américains des cancers incluant 21 546 participants, cette étude évalue les facteurs associés au risque de second cancer de l'ovaire ou du testicule, chez les femmes et les enfants atteints de tumeurs des cellules germinales ayant déjà été traitées (1 cas chez les femmes, 25 cas chez les garçons, 2 chez les filles)

Risk of second gonadal cancers in women and children with germ cell tumors

Liao, Zi Wei ; Rodrigues, Maria Clarissa ; Poynter, Jenny N. ; Amatruda, James F. ; Rodriguez-Galindo, Carlos ; Frazier, A. Lindsay

BACKGROUND Men with testicular cancer have an increased risk of developing cancer in the contralateral testis, but the risks of second gonadal cancers (SGCs) in women and children treated for germ cell tumors (GCTs) have not previously been quantified. METHODS The incidence of SGCs was ascertained in patients who had survived for at least 1 year after GCT diagnosis using data from the Surveillance, Epidemiology, and End Results SEER 9 registries (1980-2012). Relative risks of SGCs were [...]

Menée en Italie à partir des données des registres des cancers pédiatriques, cette étude cas-témoins analyse, chez des patients ayant survécu à un cancer pédiatrique, les effets à long terme de la maladie sur leur niveau d'études et leur situation professionnelle

Surviving a childhood cancer: impact on education and employment

Maule, Milena ; Zugna, Daniela ; Migliore, Enrica ; Alessi, Daniela ; Merletti, Franco ; Onorati, Roberta ; Zengarini, Nicolás ; Costa, Giuseppe ; Spadea, Teresa

Long-term consequences of childhood cancer encompass adverse psychosocial effects that may severely limit the opportunity to live a satisfying and productive life. We assessed the social integration of adults cured of a cancer in their first 14 years of life by record linkage between the population-based Childhood Cancer Registry of Piedmont and the Turin Longitudinal Study. We compared education and employment outcomes within the cohort of survivors and between the cohort of survivors and [...]

Menée à partir de données de 5 cohortes prospectives européennes incluant 90 199 participants (10 455 cas de cancers, 4 399 décès, durée médiane de suivi : 12 ans), cette étude évalue les conséquences de la maladie sur le nombre d'années de vie perdues ajustées sur l'incapacité

Burden of Cancer in a Large Consortium of Prospective Cohorts in Europe

Tsilidis, Konstantinos K. ; Papadimitriou, Nikos ; Capothanassi, Despoina ; Bamia, Christina ; Benetou, Vassiliki ; Jenab, Mazda ; Freisling, Heinz ; Kee, Frank ; Nelen, Annemarie ; O'Doherty, Mark G. ; Scott, Angela ; Soerjomataram, Isabelle ; Tjønneland, Anne ; May, Anne M. ; Ramón Quirós, J. ; Pettersson-Kymmer, Ulrika ; Brenner, Hermann ; Schottker, Ben ; Ordóñez-Mena, José M. ; Karina Dieffenbach, Aida ; Eriksson, Sture ; Bøgeberg Mathiesen, Ellisiv ; Njølstad, Inger ; Siganos, Galatios ; Wilsgaard, Tom ; Boffetta, Paolo ; Trichopoulos, Dimitrios ; Trichopoulou, Antonia

Background: Disability-adjusted life-years (DALYs) are an indicator of mortality, morbidity, and disability. We calculated DALYs for cancer in middle-aged and older adults participating in the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES) consortium. Methods: A total of 90 199 participants from five European cohorts with 10 455 incident cancers and 4399 deaths were included in this study. DALYs were calculated as the sum of the years of life lost [...]

A partir des données des registres américains des cancers incluant 28 145 patients atteints d'un cancer colorectal diagnostiqué avant l'âge de 50 ans, cette étude analyse les disparités ethniques dans la survie

Racial/Ethnic Disparities in Survival Among Patients With Young-Onset Colorectal Cancer

Holowatyj, Andreana N. ; Ruterbusch, Julie J. ; Rozek, Laura S. ; Coté, Michele L. ; Stoffel, Elena M.

Purpose : Racial disparities in colorectal cancer (CRC) persist, despite overall reductions in morbidity and mortality. In addition, incidence is rising among individuals younger than 50 years of age. We compared the survival of young-onset CRC among non-Hispanic black (NHB), non-Hispanic white (NHW), and Hispanic individuals. Patients and Methods : Using the National Cancer Institute’s Surveillance, Epidemiology, and End Results program data, we identified individuals between the ages of 20 [...]

Menée à partir de données portant sur 7 863 patients atteints d'un cancer colorectal primitif en Australie, Canada et Etats-Unis, cette étude de cohorte prospective analyse l'association entre divers facteurs médicaux ou liés au mode de vie et le risque de développer un cancer colorectal métachrone

Risk factors for metachronous colorectal cancer following a primary colorectal cancer: A prospective cohort study

Jayasekara, Harindra ; Reece, Jeanette C. ; Buchanan, Daniel D. ; Rosty, Christophe ; Dashti, S. Ghazaleh ; Ait Ouakrim, Driss ; Winship, Ingrid M. ; Macrae, Finlay A. ; Boussioutas, Alex ; Giles, Graham G. ; Ahnen, Dennis J. ; Lowery, Jan ; Casey, Graham ; Haile, Robert W. ; Gallinger, steven ; Le Marchand, Loic ; Newcomb, Polly A. ; Lindor, Noralane M. ; Hopper, John L. ; Parry, Susan ; Jenkins, Mark A. ; Win, Aung Ko

Individuals diagnosed with colorectal cancer (CRC) are at risk of developing a metachronous CRC. We examined the associations between personal, tumour-related and lifestyle risk factors, and risk of metachronous CRC. A total of 7,863 participants with incident colon or rectal cancer who were recruited in the USA, Canada and Australia to the Colon Cancer Family Registry during 1997-2012, except those identified as high-risk, for example, Lynch syndrome, were followed up approximately every 5 [...]

Menée au Japon à partir des données de 10 registres des cancers, cette étude analyse l'évolution de l'incidence du cancer colorectal, en fonction de sa localisation anatomique, sur la période 1987-2004

Changes in trends in colorectal cancer incidence rate by anatomic site between 1978 and 2004 in Japan

Nakagawa, Hiroko ; Ito, Hidemi ; Hosono, Satoyo ; Oze, Isao ; Mikami, Haruo ; Hattori, Masakazu ; Nishino, Yoshikazu ; Sugiyama, Hiromi ; Nakata, Kayo ; Tanaka, Hideo

Although colorectal cancer (CRC), a major type of cancer worldwide, has shown a proximal or right-sided shift in subsite distribution in western countries, trends in subsite incidence in Asian countries remain unclear. Here, we evaluated subsite-specific trends in CRC incidence rate between 1978 and 2004 in Japan using large data from 10 population-based cancer registries. The colorectal sites (C18-C20) were categorized into three groups: proximal colon (C18.0-C18.5), distal colon [...]

Menée aux Etats-Unis à partir de données portant sur 1 984 patients atteints d'un cancer du côlon et inclus dans un essai de phase III, cette étude évalue l'impact d'une consommation d'alcool sur la survie

Alcohol consumption and colon cancer prognosis among participants in north central cancer treatment group phase III trial N0147

Phipps, Amanda I. ; Shi, Qian ; Limburg, Paul J. ; Nelson, Garth D. ; Sargent, Daniel J. ; Sinicrope, Frank A. ; Chan, Emily ; Gill, Sharlene ; Goldberg, Richard M. ; Kahlenberg, Morton ; Nair, Suresh ; Shields, Anthony F. ; Newcomb, Polly A. ; Alberts, Steven R. ; for the Alliance for Clinical Trials in, Oncology

Alcohol consumption is associated with a modest increased risk of colon cancer, but its relationship with colon cancer survival has not been elucidated. Using data from a phase III randomized adjuvant trial, we assessed the association of alcohol consumption with colon cancer outcomes. Patients completed a risk factor questionnaire before randomization to FOLFOX or FOLFOX + cetuximab (N = 1984). Information was collected on lifestyle factors, including smoking, physical activity and consumption [...]

Menée en Allemagne à partir de données portant sur 3 121 patients atteints d'un cancer colorectal (âge médian lors du diagnostic : 69 ans), cette étude de cohorte évalue les effets d'une consommation d'alcool, mesurée tout au long de la vie et un an avant le diagnostic, sur la survie (durée médiane de suivi : 4,8 ans)

Alcohol consumption and survival of colorectal cancer patients: population-based study from Germany

Walter, Viola ; Jansen, Lina ; Ulrich, Alexis ; Roth, Wilfried ; Blaker, Hendrik ; Chang-Claude, Jenny ; Hoffmeister, Michael ; Brenner, Hermann

Background: Studies on the association between alcohol consumption and colorectal cancer (CRC) prognosis have yielded inconsistent results. Objective: The associations of lifetime and 1-y prediagnostic alcohol consumption with relevant prognostic outcomes were evaluated in a large population-based cohort of CRC patients. Design: In 2003–2010, 3121 patients diagnosed with CRC were interviewed on sociodemographic and lifestyle factors, medication, and comorbidities. Cancer recurrence, vital [...]

A partir des données des registres américains des cancers, cette étude analyse l'évolution de la survie, sur la période entre 1992 et 2012, chez les patients âgés de plus de 65 ans et atteints d'une tumeur hématologique

Changes in the survival of older patients with hematologic malignancies in the early 21st century

Pulte, Dianne ; Jansen, Lina ; Castro, Felipe A. ; Brenner, Hermann

BACKGROUND Survival for patients with hematologic malignancies has improved during the early 21st century. However, it is unclear whether older patients have benefited to the same extent as younger patients. This study examines changes in survival for older patients with the 7 most common hematologic malignancies. METHODS Period analysis was used to examine survival for patients who were 65 years old or older and were diagnosed with a common hematologic malignancy between 1992 and 2012 with [...]

A partir des données des registres américains des cancers et de la base Medicare portant sur 883 patientes atteintes d'un cancer du sein de stade IV, cette étude évalue les disparités ethniques dans l'utilisation précoce de médicaments pour traiter les symptômes courants liés au cancer (dépression, anxiété, insomnie), puis analyse l'impact de leur utilisation sur les soins de fin de vie

Investigation of Racial Disparities in Early Supportive Medication Use and End-of-Life Care Among Medicare Beneficiaries With Stage IV Breast Cancer

Check, Devon K. ; Samuel, Cleo A. ; Rosenstein, Donald L. ; Dusetzina, Stacie B.

Purpose : Early supportive care may improve quality of life and end-of-life care among patients with cancer. We assessed racial disparities in early use of medications for common cancer symptoms (depression, anxiety, insomnia) and whether these potential disparities modify end-of-life care. Methods : We used 2007 to 2012 SEER-Medicare data to evaluate use of supportive medications (opioid pain medications and nonopioid psychotropics, including antidepressants/anxiolytics and sleep aids) in the [...]

Menée aux Etats-Unis à partir de données portant sur 3 016 patientes atteintes d'un cancer invasif du sein (âgées de 18 à 64 ans) et par enquête auprès de 1 540 professionnels de santé (chirurgiens et oncologues), cette étude analyse les disparités ethniques dans le recours à un test de détection de mutations BRCA1 ou BRCA12

Health Care Segregation, Physician Recommendation, and Racial Disparities in BRCA1/2 Testing Among Women With Breast Cancer

McCarthy, Anne Marie ; Bristol, Mirar ; Domchek, Susan M. ; Groeneveld, Peter W. ; Kim, Younji ; Motanya, U. Nkiru ; Shea, Judy A. ; Armstrong, Katrina

Purpose : Racial disparities in BRCA1/2 testing have been documented, but causes of these disparities are poorly understood. The study objective was to investigate whether the distribution of black and white patients across cancer providers contributes to disparities in BRCA1/2 testing. Patients and Methods : We conducted a population-based study of women in Pennsylvania and Florida who were 18 to 64 years old and diagnosed with invasive breast cancer between 2007 and 2009, linking cancer [...]

A partir d'une revue systématique de la littérature (36 études), cette méta-analyse évalue l'efficacité des psychothérapies comportementales destinées aux aidants de patients atteints de cancer et aux patients ayant survécu à un cancer

Cognitive behavioral therapies for informal caregivers of patients with cancer and cancer survivors: a systematic review and meta-analysis

O'Toole, Mia S. ; Zachariae, Robert ; Renna, Megan E. ; Mennin, Douglas S. ; Applebaum, Allison

Objective : Informal caregivers (ICs) of patients with cancer and cancer survivors report a number of psychological and physical complaints because of the burden associated with providing care. Given the documented effect of Cognitive Behavioral Therapy (CBT) on ICs' common psychological complaints, such as anxiety and depression, the objective was to conduct a meta-analysis on the effect of CBTs for adult ICs. Methods : A literature search was conducted in order to identify all intervention [...]

Menée aux Etats-Unis par questionnaire auprès de 40 patients adolescents atteints de cancer, cette étude prospective analyse leurs perceptions et leurs définitions du concept du "bon patient" (incluant la participation dans la prise de décison thérapeutique, l'adhésion au traitement, les interactions sociales, etc)

“Being a good patient” during times of illness as defined by adolescent patients with cancer

Weaver, Meaghann S. ; Baker, Justin N. ; Gattuso, Jami S. ; Gibson, Deborah V. ; Hinds, Pamela S.

BACKGROUND Adolescents with cancer cite the opinions of others and expected impact on others as formative for their care preferences and decisions. The current study first explores how the concepts of being a good child and being a good patient may exist for adolescents with cancer and determines how adolescents describe and apply these concepts. The study then investigates parental actions and clinician behaviors perceived by adolescents with cancer as supportive in helping them to achieve [...]

Menée au Canada par enquête auprès de 117 patientes ayant survécu à un cancer du sein, cette étude transversale analyse l'association entre leurs représentations de la maladie et la peur de la récidive

The relationship between illness representations, risk perception and fear of cancer recurrence in breast cancer survivors

Freeman-Gibb, Laurie A. ; Janz, Nancy K. ; Katapodi, Maria C. ; Zikmund-Fisher, Brian J. ; Northouse, Laurel

Objective : Fear of cancer recurrence, although distinct from distress continues to be under-evaluated, captured, or treated when standard distress scales are used to assess concerns of cancer survivors. We tested a model assessing the association of demographic and clinical factors, illness representations, and perceived risk with fear of cancer recurrence in breast cancer survivors. Methods : We recruited 117 breast cancer survivors at least one year after completing breast cancer treatment [...]

A partir d'une revue systématique de la littérature (25 études quantitatives et 33 études qualitatives), cette étude analyse le rôle du médecin généraliste dans les soins de suivi dédiés à l'après-cancer

The role of the GP in follow-up cancer care: a systematic literature review

Meiklejohn, Judith A. ; Mimery, Alexander ; Martin, Jennifer H. ; Bailie, Ross ; Garvey, Gail ; Walpole, Euan T. ; Adams, Jon ; Williamson, Daniel ; Valery, Patricia C.

Purpose: The purpose of the present study is to explore the role of the general practitioners, family physicians and primary care physicians (GP) in the provision of follow-up cancer care. Methods : PubMed, MEDLINE and CINAHL were systematically searched for primary research focussing on the role of the GP from the perspective of GPs and patients. Data were extracted using a standardised form and synthesised using a qualitative descriptive approach. Results : The initial search generated 6487 [...]

A partir des données des registres américains des cancers et de la base Medicare incluant 2 460 patientes atteintes d'un cancer du sein métastatique, cette étude analyse les coûts associés à l'utilisation très fréquente de tests permettant de surveiller l'évolution de la maladie (marqueurs sériques tumoraux, radiographies)

Use and Costs of Disease Monitoring in Women With Metastatic Breast Cancer

Accordino, Melissa K. ; Wright, Jason D. ; Vasan, Sowmya ; Neugut, Alfred I. ; Hillyer, Grace C. ; Hu, Jim C. ; Hershman, Dawn L.

Purpose : The optimal frequency of monitoring patients with metastatic breast cancer (MBC) is unknown; however, data suggest that intensive monitoring does not improve outcomes. We performed a population-based analysis to evaluate patterns and predictors of extreme use of disease-monitoring tests (serum tumor markers [STMs] and radiographic imaging) among women with MBC. Methods : The SEER-Medicare database was used to identify women with MBC diagnosed from 2002 to 2011 who underwent disease [...]

A partir d'une revue systématique de la littérature, cette étude évalue l'efficacité des outils de détection et de prise en charge d'une polymédication chez les patients âgés atteints de cancer

A Comprehensive Look at Polypharmacy and Medication Screening Tools for the Older Cancer Patient

Whitman, Andrew M. ; DeGregory, Kathlene A. ; Morris, Amy L. ; Ramsdale, Erika E.

Inappropriate medication use and polypharmacy are extremely common among older adults. Numerous studies have discussed the importance of a comprehensive medication assessment in the general geriatric population. However, only a handful of studies have evaluated inappropriate medication use in the geriatric oncology patient. Almost a dozen medication screening tools exist for the older adult. Each available tool has the potential to improve aspects of the care of older cancer patients, but no [...]