A partir de données portant sur 6 024 patients atteints de cancer et interrogés à l'aide du questionnaire européen EORTC QLQ-C3, cette étude analyse les effets de l'âge sur leur qualité de vie liée à la santé

The effects of age on health-related quality of life in cancer populations: A pooled analysis of randomized controlled trials using the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 involving 6024 cancer patients

Quinten, Chantal ; Coens, Corneel ; Ghislain, Irina ; Zikos, Efstathios ; Sprangers, Mirjam A. G. ; Ringash, Jolie ; Martinelli, Francesca ; Ediebah, Divine E. ; Maringwa, John ; Reeve, Bryce B. ; Greimel, Eva ; King, Madeleine T. ; Bjordal, Kristin ; Flechtner, Hans-Henning ; Schmucker-Von Koch, Joseph ; Taphoorn, Martin J. B. ; Weis, Joachim ; Wildiers, Hans ; Velikova, Galina ; Bottomley, Andrew

Background : Cancer incidence increases exponentially with advancing age, cancer patients live longer than in the past, and many new treatments focus on stabilizing disease and HRQOL. The objective of this study is to examine how cancer affects patients' HRQOL and whether their HRQOL is age-dependent. Methods : Data from 25 EORTC randomized controlled trials was pooled. EORTC QLQ-C30 mean scores for the cancer cohort and five general population cohorts were compared to assess the impact of [...]

Menée aux Etats-Unis auprès de 87 patients ayant survécu à un cancer de la prostate et auprès de 72 patientes ayant survécu à un cancer du sein, cette étude analyse l'efficacité d'une intervention de réadaptation constituée d'exercices physiques d'intensité variable pour améliorer leur qualité de vie psychosociale

Higher-intensity exercise helps cancer survivors remain motivated

Martin, Eric ; Battaglini, Claudio ; Hands, Beth ; Naumann, FionaL

Purpose : The aim of the present study was to determine if exercise intensity impacts upon the psychosocial responses of breast and prostate cancer survivors to a rehabilitation program. Methods : Eighty-seven prostate and 72 breast cancer survivors participated in an 8-week exercise and supportive group psychotherapy intervention (n = 84) or control (n = 75) group. Intervention participants were randomized to low-to-moderate intensity exercise (LIG; n = 44; 60–65 % VO2peak, 50–65 % one [...]

Mené au Canada auprès de 150 patients atteints d'un cancer du poumon métastatique et recevant un traitement par erlotinib, cet essai prospectif randomisé analyse les effets d'un traitement prophylactique à base de minocycline pour réduire les toxicités cutanées induites par le traitement

Pan Canadian Rash Trial: A Randomized Phase III Trial Evaluating the Impact of a Prophylactic Skin Treatment Regimen on Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor–Induced Skin Toxicities in Patients With Metastatic Lung Cancer

Melosky, Barbara ; Anderson, Helen ; Burkes, Ronald L. ; Chu, Quincy ; Hao, Desiree ; Ho, Vincent ; Ho, Cheryl ; Lam, Wendy ; Lee, Christopher W. ; Leighl, Natasha B. ; Murray, Nevin ; Sun, Sophie ; Winston, Robert ; Laskin, Janessa J.

Purpose : Erlotinib is an epidermal growth factor receptor inhibitor approved for patients with advanced non–small-cell lung cancer (NSCLC) whose epidermal growth factor receptor expression status is positive or unknown. Although it is efficacious, erlotinib can cause skin toxicity. This prospective, randomized phase III trial examined the effect of prophylactic treatment of erlotinib-induced skin rash. Patients and Methods : Patients receiving erlotinib in the second- or third-line setting for [...]

Mené au Danemark auprès de 25 patients atteints d'un cancer de la prostate, cet essai randomisé évalue les effets à 2 ans d'une intervention à domicile, destinée à développer l'endurance, sur les fonctions physiologiques, divers indicateurs biologiques et le niveau du PSA

Effect of a 2-year home-based endurance training intervention on physiological function and PSA doubling time in prostate cancer patients

Hvid, Thine ; Lindegaard, Birgitte ; Winding, Kamilla ; Iversen, Peter ; Brasso, Klaus ; Solomon, ThomasP J. ; Pedersen, BenteK ; Hojman, Pernille

Aim : Physical activity after prostate cancer diagnosis has been shown to reduce the risk of disease progression. Here, we aimed to evaluate the effect of a 2-year home-based endurance training intervention on body composition, biomarkers levels, and prostate-specific antigen (PSA) doubling time as a surrogate end-point for progressing disease. Methods : Out-clinic patients with either biochemical recurrence following radical prostatectomy or patients managed on active surveillance were [...]

Menée au Canada auprès de 1 415 patientes atteintes d'un cancer du sein, cette étude compare leurs symptômes et leur qualité de vie après une mastectomie ou une tumorectomie

Quality of life and symptom burden in patients with breast cancer treated with mastectomy and lumpectomy

Chow, Ronald ; Pulenzas, Natalie ; Zhang, Liying ; Ecclestone, Christine ; Leahey, Angela ; Hamer, Julia ; DeAngelis, Carlo ; Bedard, Gillian ; McDonald, Rachel ; Bhatia, Anchal ; Ellis, Janet ; Rakovitch, Eileen ; Vuong, Sherlyn ; Chow, Edward ; Verma, Sunil

Introduction : Mastectomy (MAS) and lumpectomy (LUMP) are the two common local surgical treatments for early breast cancer. There has been a debate whether MAS or LUMP results in better quality of life (QOL). The purpose of this study was to examine the symptom burden (SB) and QOL of both MAS and LUMP patients. Methods : Patients at the Louise Temerty Breast Cancer Centre in Toronto, Canada, were approached to complete two self-administered questionnaires, the Edmonton Symptom Assessment Score [...]

A partir des données de la cohorte "VITamins And Lifestyle (VITAL) Study" incluant 54 737 participants âgés de 50 à 76 ans, cette étude évalue l'effet de comportements de santé (activité physique, alimentation, tabagisme, consommation d'alcool) sur l'association géographique entre caractéristiques socio-économiques et mortalité par cancer

Contribution of health behaviors to the association between area-level socioeconomic status and cancer mortality

Hastert, Theresa A. ; Ruterbusch, Julie J. ; Beresford, Shirley A. A. ; Sheppard, Lianne ; White, Emily

Cancer mortality is higher among residents of low-socioeconomic status (SES) areas than those of high-SES areas; however, the contribution of modifiable risk factors to this disparity is not known. We used data from 54,737 participants in the VITamins And Lifestyle (VITAL) Study, aged 50-76 with no history of cancer at baseline (2000-2002). Of these, 1,488 died of cancer over an average of 7.7 years of follow-up. Data on modifiable risk factors including body mass index (BMI), physical [...]

A partir des données de la cohorte européenne EPIC incluant 370 000 participantes âgées de 25 à 70 ans, cette étude évalue l'association entre des facteurs reproductifs (parité, allaitement, contraception orale, traitement hormonal substitutif de la ménopause) et la survie des patientes atteintes d'un cancer épithélial de l'ovaire (1 025 décès)

Reproductive factors and epithelial ovarian cancer survival in the EPIC cohort study

Besevic, Jelena ; Gunter, Marc J. ; Fortner, Renée T. ; Tsilidis, Konstantinos K. ; Weiderpass, Elisabete ; Charlotte Onland-Moret, N. ; Dossus, Laure ; Tjonneland, Anne ; Hansen, Louise ; Overvad, Kim ; Mesrine, Sylvie ; Baglietto, Laura ; Clavel-Chapelon, Françoise ; Kaaks, Rudolf ; Aleksandrova, Krasimira ; Boeing, Heiner ; Trichopoulou, Antonia ; Lagiou, Pagona ; Bamia, Christina ; Masala, Giovanna ; Agnoli, Claudia ; Tumino, Rosario ; Ricceri, Fulvio ; Panico, Salvatore ; Bueno-de-Mesquita, H. B. ; Peeters, Petra H. ; Jareid, Mie ; Ramón Quirós, J. ; Duell, Eric J. ; Sánchez, María-José ; Larranaga, Nerea ; Chirlaque, María-Dolores ; Barricarte, Aurelio ; Dias, Joana A. ; Sonestedt, Emily ; Idahl, Annika ; Lundin, Eva ; Wareham, Nicholas J. ; Khaw, Kay-Tee ; Travis, Ruth C. ; Rinaldi, Sabina ; Romieu, Isabelle ; Riboli, Elio ; Merritt, Melissa A.

Background : Reproductive factors influence the risk of developing epithelial ovarian cancer (EOC), but little is known about their association with survival. We tested whether prediagnostic reproductive factors influenced EOC-specific survival among 1025 invasive EOC cases identified in the European Prospective Investigation into Cancer and Nutrition (EPIC) study, which included 521 330 total participants (approximately 370 000 women) aged 25–70 years at recruitment from 1992 to 2000. Methods: [...]

Menée aux Etats-Unis à partir de données portant sur 1 140 patientes atteintes d'un cancer du sein, cette étude évalue l'association entre des critères reproductifs (nombre d'enfants, temps écoulé depuis la dernière naissance) et la survie des patientes, en fonction du sous-type de la maladie (durée médiane de suivi : 13,5 ans)

Association of Parity and Time since Last Birth with Breast Cancer Prognosis by Intrinsic Subtype

Sun, Xuezheng ; Nichols, Hazel B ; Tse, Chiu-Kit ; Bell, Mary B ; Robinson, Whitney R ; Sherman, Mark E. ; Olshan, Andrew F. ; Troester, Melissa A.

Background:Parity and time since last birth influence breast cancer risk and vary by intrinsic tumor subtype, but the independent effects of these factors on prognosis has received limited attention. Methods:Study participants were 1,140 invasive breast cancer patients from Phases I and II of the population-based Carolina Breast Cancer Study, with tissue blocks available for subtyping using immunohistochemical markers. Breast cancer risk factors, including pregnancy history, were collected via [...]

Menée aux Pays-Bas auprès de 815 patientes atteintes d'un cancer du sein métastatique HR+, cette étude analyse les facteurs associés au choix d'une chimiothérapie palliative initiale et évalue son impact sur la survie des patientes

In real life, one-quarter of patients with hormone receptor positive metastatic breast cancer receive chemotherapy as initial palliative therapy A study of the Southeast Netherlands Breast Cancer Consortium

Lobbezoo, D.J.A. ; van Kampen, R.J.W. ; Voogd, A.C. ; Dercksen, M.W. ; van den Berkmortel, F. ; Smilde, T.J. ; van de Wouw, A.J. ; Peters, F.P.J. ; van Riel, J.M.G.H. ; Peters, N.A.J.B. ; de Boer, M. ; Peer, P.G.M. ; Tjan-Heijnen, V.C.G.

Background : The objective of this study was to present initial systemic treatment choices and outcome of hormone receptor positive (HR+) metastatic breast cancer. Patients and methods : All 815 consecutive patients diagnosed with metastatic breast cancer in 2007-2009 in eight participating hospitals were identified. From the 611 patients with HR+ disease, a total of 520 patients with HER2 negative (HER2-) breast cancer was included. Initial palliative systemic treatment was registered. [...]

Menée aux Etats-Unis auprès de 1 382 patientes atteintes d'un carcinome canalaire in situ récemment diagnostiqué, cette étude évalue l'association entre le statut marital, le statut socio-économique et l'évolution des comportements de santé après le diagnostic

Partnership Status and Socioeconomic Factors in Relation to Health Behavior Changes after a Diagnosis of Ductal Carcinoma in situ

Khadanga, Sherrie ; Lakoski, Susan G ; Hart, Vicki ; Sprague, Brian L ; Ba, Yi ; Hampton, John M ; Higgins, Stephen T ; Ades, Philip A ; Newcomb, Polly A. ; Trentham-Dietz, Amy

Background: Change in health behaviors can occur among women newly diagnosed with DCIS. We sought to understand whether partnership status and socioeconomic status (SES) impacted behavioral changes in body weight, physical activity, alcohol consumption, and smoking. Methods: The Wisconsin In Situ Cohort (WISC) study comprises 1,382 women diagnosed with DCIS with information on demographics, SES factors, and pre- and post-DCIS diagnosis health-related behaviors. Logistic regression models were [...]

Menée aux Etats-Unis à partir de données portant sur 15 538 patientes atteintes d'un cancer du sein et incluses dans 4 essais cliniques, cette étude évalue l'association entre l'indice de masse corporelle mesuré au moment du diagnostic, les différents traitements, le risque de récidive et la survie des patientes

Body mass index at diagnosis and breast cancer survival prognosis in clinical trial populations from NRG Oncology/NSABP B-30, B-31, B-34, and B-38

Cecchini, Reena ; Swain, Sandra M ; Costantino, Joseph P ; Rastogi, Priya ; Jeong, Jong-Hyeon ; Anderson, Stewart J ; Tang, Gong ; Geyer, Charles E ; Lembersky, Barry C ; Romond, Edward H ; Paterson, Alexander H.G. ; Wolmark, Norman

Background: Body mass index (BMI) has been associated with breast cancer (BC) outcomes. However, few studies used clinical trial settings where treatments and outcomes are consistently evaluated and documented. There are also limited data assessing how patient/disease characteristics and treatment may alter the BMI/BC association. Methods: We evaluated 15,538 BC participants from four NSABP protocols. B-34 studied early-stage BC patients (N=3,311); B-30 and B-38 included node-positive BC [...]

Menée au Danemark à partir de données portant sur 476 patients atteints d'un cancer de la tête et du cou, cette étude identifie les facteurs prédictifs associés à une perte de poids importante pendant la radiothérapie

Prediction of critical weight loss during radiation treatment in head and neck cancer patients is dependent on BMI

Lønbro, Simon ; Petersen, GryBjerg ; Andersen, JensRikardt ; Johansen, Jørgen

Purpose : The aims of the present study were to explore pre-treatment predictors of weight loss during radiation treatment only in head and neck cancer (HNSCC) patients and investigate the weight loss in patients with or without a feeding tube. Methods : Retrospectively, weight change during curative radiotherapy was investigated in 476 consecutive HNSCC patients. Independent predictors were identified using multivariate regression analysis with weight loss below or above 5 % as the primary [...]

A partir d'échantillons tumoraux prélévés sur 529 patients atteints d'un cancer épidermoïde de l'oropharynx, cette étude évalue l'association entre une infection par le papillomavirus humain et la survie des patients

Human papillomavirus genotype and oropharynx cancer survival in the United States of America

Goodman, Marc T. ; Saraiya, Mona ; Thompson, Trevor D. ; Steinau, Martin ; Hernandez, Brenda Y. ; Lynch, Charles F. ; Lyu, Christopher W. ; Wilkinson, Edward J. ; Tucker, Thomas ; Copeland, Glenn ; Peters, Edward S. ; Altekruse, Sean ; Unger, Elizabeth R.

Background : The presence of human papillomavirus (HPV) DNA in oropharyngeal squamous cell cancer (OPSCC) tissue appears to be a strong predictor of improved prognosis, but this observation has not been explored in a population-based sample with generalisable findings. Methods : Follow-up data from a large sample of OPSCC patients identified through six population-based cancer registries in the United States of America (USA) were used to characterise the association of tumour HPV status with [...]

A partir d'une revue systématique de la littérature, cette méta-synthèse analyse le vécu des aidants familiaux de patients atteints de cancer

The Experience of Caregivers Living with Cancer Patients: A Systematic Review and Meta-Synthesis

LeSeure, Peeranuch ; Chongkham-ang, Supaporn

The objectives of this meta-synthesis were to: (1) explore the experience of caregivers who were caring for cancer patients, including their perceptions and responses to the situation; and (2) describe the context and the phenomena relevant to the experience. Five databases were used: CINAHL, MEDLINE, Academic Search, Science Direct, and a Thai database known as the Thai Library Integrated System (ThaiLIS). Three sets of the context of the experience and the phenomena relevant to the experience [...]

A partir d'une revue systématique de la littérature (36 articles identifiés), cette étude analyse les effets psychosociaux d'une alopécie chez des patients ayant survécu à un cancer

Cancer-related hair loss: a selective review of the alopecia research literature

Dua, Priya ; Heiland, Mark F. ; Kracen, Amanda C. ; Deshields, Teresa L.

Objective : Alopecia is a common side effect of cancer treatment, affecting approximately 65% of patients. Healthcare providers and allied staff recognize that alopecia is distressing for people with cancer; however, they are often unaware of the extent of distress or the great efforts expended by patients to cope with hair loss. This study reviews the existing literature regarding the psychosocial impact of alopecia on cancer survivors and the coping strategies they use to manage hair loss. [...]

Menée à partir des données de deux registres néerlandais des cancers portant sur 1 283 patients adultes ayant survécu à un cancer pédiatrique diagnostiqué entre 1966 et 2001, cette étude analyse les facteurs associés à diverses caractéristiques de leur vie sociale (vie maritale, autonomie, recours à des aides sociales, etc) en fonction des traitements reçus

Social outcomes in adult survivors of childhood cancer compared to the general population: linkage of a cohort with population registers

Font-Gonzalez, Anna ; Feijen, Elizabeth ; Sieswerda, Elske ; van Dulmen-den Broeder, Eline ; Grootenhuis, Martha ; Maurice-Stam, Helena ; Caron, Huib ; Essink-Bot, Marie-Louise ; van der Pal, Helena ; Geskus, Ronald ; Kremer, Leontien

Objective : Self-reported data show differences in social outcomes (not being married/having a registered partnership; not living independently; using social benefits) for childhood cancer survivors compared with their peers. We aimed to determine differences in these social outcomes between survivors and the general population using national register data and explored associated risk factors. Methods : We performed medical record linkage between a single-centre cohort of 1768 ≥ 5-year [...]

Cet article présente des interventions et des mesures dédiées à la lutte contre le cancer dans les pays à revenus faibles ou moyens

Costs, affordability, and feasibility of an essential package of cancer control interventions in low-income and middle-income countries: key messages from Disease Control Priorities, 3rd edition

Hellen Gelband ; Rengaswamy Sankaranarayanan ; Cindy L Gauvreau ; Prof Susan Horton ; Benjamin O Anderson ; Freddie Bray ; James Cleary ; Anna J Dare ; Lynette Denny ; Mary K Gospodarowicz ; Sumit Gupta ; Prof Scott C Howard ; David A Jaffray ; Felicia Knaul ; Carol Levin ; Linda Rabeneck ; Preeta Rajaraman ; Terrence Sullivan ; Edward L Trimble ; Prof Prabhat Jha

Investments in cancer control—prevention, detection, diagnosis, surgery, other treatment, and palliative care—are increasingly needed in low-income and particularly in middle-income countries, where most of the world's cancer deaths occur without treatment or palliation. To help countries expand locally appropriate services, Cancer (the third volume of nine in Disease Control Priorities, 3rd edition) developed an essential package of potentially cost-effective measures for countries to consider [...]

Menée en Italie par entretiens auprès de 206 patients ayant survécu à un cancer, cette étude analyse les coûts de santé restant à leur charge, 5 à 10 ans après le diagnostic de leur maladie

Out-of-pocket costs for cancer survivors between 5 and 10 years from diagnosis: an Italian population-based study

Baili, Paolo ; Di Salvo, Francesca ; De Lorenzo, Francesco ; Maietta, Francesco ; Pinto, Carmine ; Rizzotto, Vera ; Vicentini, Massimo ; Rossi, PaoloGiorgi ; Tumino, Rosario ; Rollo, PatriziaConcetta ; Tagliabue, Giovanna ; Contiero, Paolo ; Candela, Pina ; Scuderi, Tiziana ; Iannelli, Elisabetta ; Cascinu, Stefano ; Aurora, Fulvio ; Agresti, Roberto ; Turco, Alberto ; Sant, Milena ; Meneghini, Elisabetta ; Micheli, Andrea

Purpose : To illustrate the out-of-pocket (OOP) costs incurred by a population-based group of patients from 5 to 10 years since their cancer diagnosis in a country with a nationwide public health system. Methods : Interviews on OOP costs to a sample of 5–10 year prevalent cases randomly extracted from four population-based cancer registries (CRs), two in the north and two in the south of Italy. The patients’ general practitioners (GPs) gave assurance about the patient’s physical and [...]

Menée en Suède auprès de 1 971 patientes atteintes d'un cancer du col de l'utérus et de 9 254 témoins en population générale, cette étude analyse les arrêts de travail pour maladie, en fonction des modalités thérapeutiques et du risque de récidive

Lost workdays in uterine cervical cancer survivors compared to the general population: impact of treatment and relapse

Everhov, ÅsaH ; Ekberg, Sara ; Hirschberg, AngelicaLindén ; Bergmark, Karin ; Rådestad, AngeliqueFlöter ; Glimelius, Ingrid ; Smedby, KarinE

Purpose : The aim of the present study was to examine the risk of lost workdays due to sick leave and disability pension by treatment modality and relapse in a population-based cohort of cervical cancer survivors versus matched comparators. Methods: We identified 1 971 cervical cancer patients aged ≤60 years (median 42) at diagnosis in Sweden 2003–2009 and 9254 population comparators. Information on sociodemographic and clinical characteristics, sick leave, and disability pension was retrieved [...]

Menée aux Etats-Unis, cette étude analyse les échanges, lors de visites de routine à l'hôpital, entre les médecins et leurs patients atteints d'un cancer de stade précoce sur les bienfaits de la pratique d'une activité physique

Physical activity communication between oncology providers and patients with early-stage breast, colon, or prostate cancer

Nyrop, Kirsten A. ; Deal, Allison M. ; Williams, Grant R. ; Guerard, Emily J. ; Pergolotti, Mackenzi ; Muss, Hyman B.

BACKGROUND National guidelines recommend that patients with a cancer diagnosis engage in regular physical activity to reduce cancer-related fatigue, maintain quality of life and physical function, and improve overall prognosis and survival. This study investigates oncology provider communications about physical activity during routine clinic visits with patients with early-stage breast, colon, or prostate cancer. METHODS This study used a retrospective chart review for documentation of [...]

Menée aux Etats-Unis auprès de 231 patients atteints d'un cancer du poumon, cette étude transversale évalue l'association entre la qualité de la communication avec le personnel soignant et la stigmatisation dont les patients se sentent victimes

Association between patient-provider communication and lung cancer stigma

Shen, MeganJohnson ; Hamann, HeidiA ; Thomas, AnnaJ ; Ostroff, JamieS

Purpose : The majority (95 %) of lung cancer patients report stigma, with 48 % of lung cancer patients specifically reporting feeling stigmatized by their medical providers. Typically associated with the causal link to smoking and the historically poor prognosis, lung cancer stigma can be seen as a risk factor for poor psychosocial and medical outcomes in the context of lung cancer diagnosis and treatment. Thus, modifiable targets for lung cancer stigma-reducing interventions are needed. The [...]

Menée en Chine à partir de données portant sur 436 patients atteints d'un cancer en phase terminale, cette étude analyse les caractéritiques et les facteurs associés aux prises de décisions relatives à la fin de vie

End-of-life decision-making of terminally ill cancer patients in a tertiary cancer center in Shanghai, China

Gu, Xiaoli ; Chen, Menglei ; Liu, Minghui ; Zhang, Zhe ; Cheng, Wenwu

Purpose : Different countries have various decision-making practices, which are formalized according to laws, rules, traditions, religious beliefs, and ethical views of different cultural backgrounds. We investigated the characteristics and factors associated with the decision-making details in terminally ill cancer patients in a tertiary cancer center in Shanghai, China. Method : A single center, retrospective study was performed among advanced cancer patients who died between March 2007 and [...]

Menée aux Etats-Unis auprès de 472 patients atteints d'un cancer de stade avancé, cette étude évalue l'association entre l'évolution de leur état de santé physique et psychique en fin de vie, la prise en charge des symptômes, les soins palliatifs reçus et la survie

Longitudinal patterns of cancer patient reported outcomes in end of life care predict survival

Stukenborg, GeorgeJ ; Blackhall, Leslie J. ; Harrison, JamesH ; Dillon, PatrickM ; Read, PaulW

Purpose : Patients with advanced cancer typically demonstrate sharp deterioration in physical function and psychological status during the last months of life. This study evaluates the relationship between survival in patients with advanced cancer and longitudinal assessment of anxiety, depression, fatigue, pain interference, and/or physical function using the US National Institute of Health Patient Reported Outcomes Information System. Methods : Mixed-effects models were used to evaluate [...]

Menée en Autriche auprès de 50 patients atteints de cancer et recevant des soins palliatifs, cette étude pilote évalue l'intérêt d'un outil, basé sur 7 items, pour évaluer leurs symptômes

The PERS2ON score for systemic assessment of symptomatology in palliative care: a pilot study

Masel, E. K. ; Berghoff, A. S. ; Schur, S. ; Maehr, B. ; Schrank, B. ; Simanek, R. ; Preusser, M. ; Marosi, C. ; Watzke, H. H.

The comprehensive assessment of symptoms is the basis for effective, individualised palliative treatment. Established scoring systems provide in-depth information but are often lengthy and hence unsuitable. We introduce the PERS2ON score as a short and practically feasible score to evaluate symptom burden. Fifty patients admitted to a Palliative Care Unit rated seven items, i.e. pain, eating (loss of appetite/weight loss), rehabilitation (physical impairment), social situation (possibility for [...]

Menée aux Etats-Unis auprès de 552 patientes ayant survécu à un cancer du sein, cette étude observationnelle analyse leurs croyances relatives aux causes de leur maladie, puis évalue l'impact de ces croyances sur leurs préférences thérapeutiques, dont le recours à des médecines complémentaires ou alternatives

The ‘cause’ of my cancer, beliefs about cause among breast cancer patients and survivors who do and do not seek IO care

Andersen, M. Robyn ; Afdem, Kelsey ; Hager, Shelly ; Gaul, Marcia ; Sweet, Erin ; Standish, Leanna J.

Objective : We sought to describe survivors' beliefs about the cause of their breast cancer and to test the hypothesis that beliefs about cancer's cause are associated with treatment preferences in accordance with the common sense model of self-regulation of health and illness. Methods : Breast cancer survivors (n = 552) participating in an observational study of cancer outcomes responded to an open-ended question about the cause of their cancer. Of these, 245 women had sought treatment from [...]