Menée aux Etats-Unis à partir des données portant sur 485 patients adolescents et jeunes adultes atteints de cancer (âge de 15 à 39 ans), cette étude analyse l'efficacité d'un outil permettant d'évaluer l'impact des comorbidités sur leur état de santé et leurs besoins en soins

Impact of the AYA HOPE comorbidity index on assessing health care service needs and health status among adolescents and young adults with cancer

Wu, Xiao-Cheng ; Prasad, Pinki K. ; Landry, Ian ; Harlan, Linda C. ; Parsons, Helen M. ; Lynch, Charles F. ; Smith, Ashley Wilder ; Hamilton, Ann S. ; Keegan, Theresa H.M.

Background: Existing comorbidity indices were not developed for adolescent and young adults (AYA) 15-39 years of age. The aim of this study was to assess impact of comorbidities on healthcare service needs and health status among AYA cancer survivors using the newly developed AYA HOPE comorbidity index in comparison with the existing indices. Methods: Data on comorbid conditions were obtained from medical records and service needs and health status were from a survey of AYA cancer survivors. [...]

A partir des données de 4 études incluant 918 patients atteints de cancer, cette méta-analyse évalue l'association entre un régime alimentaire spécifique pour limiter les effets d'une neutropénie, le risque d'infections et la mortalité

The Effect of a Neutropenic Diet on Infection and Mortality Rates in Cancer Patients: A Meta-Analysis

Sonbol, Mohamad Bassam ; Firwana, Belal ; Diab, Maria ; Zarzour, Ahmad ; Witzig, Thomas E.

Neutropenic diets (ND) are often prescribed to cancer patients aiming to reduce infection risk. The goal of this meta-analysis was to determine if ND indeed reduced the risk of infection and death in cancer patients compared to regular diets (RD). We identified studies in cancer patients that compared the effect of ND vs. RD on the risk of infections and mortality of any cause. The overall effect was calculated by use of a random effects model. Four studies were identified encompassing 918 [...]

A partir d'une revue systématique de la littérature (11 essais randomisés incluant 1 077 participants), cette étude analyse l'efficacité des interventions nutritionnelles destinées à réduire et prendre en charge la malnutrition chez des patients atteints de cancer

Nutrition intervention approaches to reduce malnutrition in oncology patients: a systematic review

Lee, JiaLiCharmaine ; Leong, LaiPeng ; Lim, SuLin

Purpose : Malnutrition is a very common problem in oncology patients and is associated with many negative consequences including poorer prognosis, quality of life and survival. However, malnutrition in oncology patients is often overlooked although there is growing evidence showing that it can be prevented or reduced through nutrition intervention. This paper aims to provide an updated review on the effectiveness of different nutrition intervention approaches on nutrition status outcomes in [...]

Menée auprès de 23 patientes atteintes d'un cancer de la vulve (âge moyen : 60 ans), cette étude prospective britannique analyse les effets d'un traitement chirurgical sur leur qualité de vie (durée de suivi : 1 an)

The impact of surgery for vulval cancer upon health-related quality of life and pelvic floor outcomes during the first year of treatment: a longitudinal, mixed methods study

Jones, Georgina L. ; Jacques, Richard M. ; Thompson, Joanne ; Wood, Hilary J. ; Hughes, Jane ; Ledger, William ; Alazzam, Mo'iad ; Radley, Stephen C. ; Tidy, John A.

Objective : To measure the long-term impact of surgical treatment for vulval cancer upon health-related quality of life and pelvic floor outcomes during the first year of therapy. Methods : Prospective, longitudinal, mixed-methods study. Twenty-three women aged >18 years with a new diagnosis of vulval cancer were recruited. The EORTC QLQ C30, SF-36 and an electronic pelvic floor assessment questionnaire (ePAQ-PF) were administered at baseline (pre-treatment) and 3, 6, 9 and 12 months [...]

Menée au Canada par enquête en ligne auprès de 206 patients atteints d'un cancer de la prostate et de 66 partenaires de vie, cette étude analyse les effets d'une thérapie anti-androgénique sur la sexualité des couples

The perspective of prostate cancer patients and patients' partners on the psychological burden of androgen deprivation and the dyadic adjustment of prostate cancer couples

Hamilton, Lisa Dawn ; Van Dam, Dexter ; Wassersug, Richard J.

Objective : Prostate cancer and its treatments, particularly androgen deprivation therapy (ADT), affect both patients and partners. This study assessed how prostate cancer treatment type, patient mood, and sexual function related to dyadic adjustment from patient and partner perspectives. Methods : Men with prostate cancer (n = 206) and partners of men with prostate cancer (n = 66) completed an online survey assessing the patients' mood (profile of mood states short form), their dyadic [...]

Menée au Brésil auprès de 133 patients atteints d'un cancer de la cavité buccale, cette étude de cohorte rétrospective analyse l'efficacité de soins buccaux préventifs pour réduire les effets indésirables et les complications liés à la radiothérapie

The effect of preventive oral care on treatment outcomes of a cohort of oral cancer patients

Morais, MariliaOliveira ; Elias, MarcelaRamosAbrahão ; Leles, CláudioRodrigues ; Dourado Pinezi, JulianaCastro ; Francisco Mendonça, Elismauro

Purpose : The purpose of this study was to assess patient adherence to an oral preventive measures (OPM) protocol and its impact on cancer treatment outcomes. Methods : A retrospective cohort of oral cancer of 133 patients submitted to radiotherapy (RT) was selected, excluding those with metastasis. Patients were grouped according to their local tumor response after finishing RT (favorable or unfavorable) and adherence to an OPM (none, ≤6 months, and >6 months). OPM included education and [...]

A partir des données d'un registre américain des cancers portant sur 3 344 patients atteints d'un cancer diagnostiqué avant l'âge de 21 ans, cette étude analyse les caractéristiques associées à la survie conditionnelle (localisation de cancer, sexe, âge au diagnostic, traitements reçus, etc)

Conditional survival for pediatric and adolescent patients with cancer: Implications for survivorship care

Kaul, Sapna ; Kirchhoff, Anne C. ; Boucher, Kenneth M. ; Dietz, Andrew C.

Purpose : Few studies have evaluated conditional survival (probability of surviving y years given patients have already survived x years) for pediatric/adolescent patients diagnosed with cancer. To provide more accurate information on ongoing survival, we evaluate conditional survival for pediatric and adolescent patients with cancer. Methods : The statewide Utah Cancer Registry identified 3344 patients born in Utah diagnosed with cancer at ages 0–21 years, from 1973 to 2009. The Utah [...]

A partir des données des registres américains des cancers, cette étude analyse l'évolution des traitements des patientes atteintes d'un carcinome canalaire in situ diagnostiqué sur la période 1991-2010

Trends in Treatment Patterns and Outcomes for Ductal Carcinoma In Situ

Worni, Mathias ; Akushevich, Igor ; Greenup, Rachel ; Sarma, Deba ; Ryser, Marc D. ; Myers, Evan R. ; Hwang, E. Shelley

Background: Impact of contemporary treatment of pre-invasive breast cancer (ductal carcinoma in situ [DCIS]) on long-term outcomes remains poorly defined. We aimed to evaluate national treatment trends for DCIS and to determine their impact on disease-specific (DSS) and overall survival (OS). Methods: The Surveillance, Epidemiology, and End Results (SEER) registry was queried for patients diagnosed with DCIS from 1991 to 2010. Treatment pattern trends were analyzed using Cochran-Armitage trend [...]

Menée aux Etats-Unis par enquête en ligne auprès de 151 patients adultes ayant survécu à un cancer pédiatrique, cette étude analyse les facteurs associés à la divulgation de leur maladie à leurs collègues de travail

Adult survivors of childhood cancers’ identity disclosures in the workplace

Martinez, LarryR ; Hebl, MichelleR

Purpose : Recent medical advances have resulted in unprecedented increases in the number and vitality of employed adult survivors. These survivors must make decisions about whether or not to disclose their identities to others. The purpose of this study was to examine the characteristics that are related to cancer survivorship disclosure in workplace settings (perceived organizational support, centrality of survivorship to one’s self-concept, and the degree to which family and friends know [...]

Menée aux Etats-Unis par questionnaire auprès de 470 patients adultes ayant survécu à un rétinoblastome et de 2 820 témoins, cette étude analyse leurs symptômes de détresse psychologique (dépression, anxiété, somatisation, peur de la récidive, satisfaction relative à leur apparence physique, stress post-traumatique, etc)

Psychosocial Outcomes in Adult Survivors of Retinoblastoma

Ford, Jennifer S. ; Chou, Joanne F. ; Sklar, Charles A. ; Oeffinger, Kevin C. ; Novetsky Friedman, Danielle ; McCabe, Mary ; Robison, Leslie L. ; Kleinerman, Ruth A. ; Li, Yuelin ; Marr, Brian P. ; Abramson, David H. ; Dunkel, Ira J.

Purpose : Survival rates for individuals diagnosed with retinoblastoma (RB) exceed 95% in the United States; however, little is known about the long-term psychosocial outcomes of these survivors. Patients and Methods : Adult RB survivors, diagnosed from 1932 to 1994 and treated in New York, completed a comprehensive questionnaire adapted from the Childhood Cancer Survivor Study (CCSS), by mail or telephone. Psychosocial outcomes included psychological distress, anxiety, depression, [...]

Menée en Australie par enquête en ligne auprès de 289 patients atteints d'un cancer de la prostate, cette étude analyse leurs difficultés financières liées aux coûts des traitements restant à charge

Financial toxicity: a potential side effect of prostate cancer treatment among Australian men

Gordon, L. G. ; Walker, S. M. ; Mervin, M. C. ; Lowe, A. ; Smith, D. P. ; Gardiner, R. A. ; Chambers, S. K.

The purpose of this study was to understand the extent, nature and variability of the current economic burden of prostate cancer among Australian men. An online cross-sectional survey was developed that combined pre-existing economic measures and new questions. With few exceptions, the online survey was viable and acceptable to participants. The main outcomes were self-reported out-of-pocket costs of prostate cancer diagnosis and treatment, changes in employment status and household finances. [...]

Menée en Australie par entretiens téléphoniques auprès de 17 patients ayant survécu à un cancer, cette étude qualitative analyse les obstacles à des discussions sur la sexualité masculine après le cancer

Let's talk about sex after cancer: exploring barriers and facilitators to sexual communication in male cancer survivors

Seidler, Zac E. ; Lawsin, Catalina R. ; Hoyt, Michael A. ; Dobinson, Katherine A.

Objective : Changes to sexuality are a primary concern amongst cancer survivors, leading to psychological distress and impacting long-term quality of life. Effective sexual communication has been found to be critical in improving sexual satisfaction post-treatment. However, research suggests that many men struggle to disclose sexual concerns and preferences. This study aimed to qualitatively explore the common barriers and facilitators to sexual communication in male cancer survivors (MCSs). [...]

Mené aux Etats-Unis auprès de 52 patients âgés de 15 à 28 ans ayant survécu à un cancer pédiatrique, cet essai randomisé évalue l'efficacité d'un outil en ligne personnalisé destiné à améliorer leurs connaissances sur leur maladie et les effets secondaires des traitements reçus

A randomized controlled pilot trial of a Web-based resource to improve cancer knowledge in adolescent and young adult survivors of childhood cancer

Kunin-Batson, Alicia ; Steele, Jeanne ; Mertens, Ann ; Neglia, Joseph P.

Objective : This study examined cancer knowledge in adolescent and young adult (AYA) survivors and pilot tested a Web-based resource to provide individually tailored information regarding cancer treatment history, late effects risk, and resources. Methods : Fifty-two survivors (15–28 years old) who completed cancer treatment were recruited from the University of Minnesota oncology clinics. Participants were randomly assigned to receive access to personalized health history, late effects [...]

Menée aux Pays-Bas auprès de 999 patients atteints d'un cancer de la prostate diagnostiqué entre 2006 et 2009, cette étude analyse leur insatisfaction relative à l'information reçue, leur perception de la maladie et leur qualité de vie

Patients are dissatisfied with information provision: perceived information provision and quality of life in prostate cancer patients

Lamers, Romy E. D. ; Cuypers, Maarten ; Husson, Olga ; de Vries, Marieke ; Kil, Paul J. M. ; Ruud Bosch, J. L. H. ; van de Poll-Franse, Lonneke V.

Objective : To determine the satisfaction with information received by prostate cancer survivors and associations with health-related quality of life (HRQoL) and illness perception. Methods : A cross-sectional study was performed among 999 patients diagnosed between 2006 and 2009. All patients received a questionnaire on HRQoL (EORTC QLQ-C30), illness perception (B-IPQ) and satisfaction with information provision (EORTC QLQ-INFO-25). Multivariate regression analyses were performed to assess the [...]

Menée en Espagne par entretiens auprès de 41 patientes atteintes d'un cancer du sein, cette étude qualitative analyse leurs expériences relatives à l'information et à la communication avec les soignants pendant les traitements

Breast cancer patients’ narrative experiences about communication during the oncology care process: a qualitative study

Abt Sacks, A. ; Perestelo-Perez, L. ; Rodriguez-Martin, B. ; Cuellar-Pompa, L. ; Algara López, M. ; González Hernández, N. ; Serrano-Aguilar, P.

To analyse the perception about the information and communication received to evaluate oncologic care of breast cancer patients in Spain. Qualitative study based on conducting in-depth interviews. An inductive thematic analysis of the illness narratives was performed. Intentional theoretical sampling of 41 people diagnosed with breast cancer. The information provided during care process is assessed as appropriate, as it includes personalised skills focused on communication and considers [...]

Menée aux Etats-Unis par enquête auprès de 120 spécialistes des cancers hématologiques et 120 spécialistes des tumeurs solides, cette étude analyse leurs pratiques vis-à-vis des soins de support et des soins palliatifs

Attitudes and Beliefs Toward Supportive and Palliative Care Referral Among Hematologic and Solid Tumor Oncology Specialists

Hui, David ; Park, Minjeong ; Liu, Diane ; Reddy, Akhila ; Dalal, Shalini ; Bruera, Eduardo

Palliative care (PC) referrals are often delayed for patients with hematologic malignancies. We examined the differences in attitudes and beliefs toward PC referral between hematologic and solid tumor specialists and how their perception changed with use of the service name “supportive care” (SC).We randomly surveyed 120 hematologic and 120 solid tumor oncology specialists at our tertiary care cancer center to examine their attitudes and beliefs toward PC and SC referral.Of the 240 specialists, [...]

Menée aux Etats-Unis à partir de données portant sur 609 patients atteints d'un cancer de stade avancé et traités dans des unités de soins palliatifs, cette étude analyse les caractéristiques associées à un état confusionnel, ainsi que la survie des patients

The Frequency, Characteristics, and Outcomes Among Cancer Patients With Delirium Admitted to an Acute Palliative Care Unit

de la Cruz, Maxine ; Ransing, Viraj ; Yennu, Sriram ; Wu, Jimin ; Liu, Diane ; Reddy, Akhila ; Delgado-Guay, Marvin ; Bruera, Eduardo

Delirium is a common neuropsychiatric condition seen in patients with severe illness, such as advanced cancer. Few published studies are available of the frequency, course, and outcomes of standardized management of delirium in advanced cancer patients admitted to acute palliative care unit (APCU). In this study, we examined the frequency, characteristics, and outcomes of delirium in patients with advanced cancer admitted to an APCU.Medical records of 609 consecutive patients admitted to the [...]

Menée aux Pays-Bas auprès de 34 patients atteints de gliome et présentant des antécédents d'épilepsie, cette étude analyse l'efficacité de traitements anti-épileptiques pendant la phase terminale de leur maladie

Antiepileptic drug treatment in the end-of-life phase of glioma patients: a feasibility study

Koekkoek, JohanA F. ; Postma, TjeerdJ ; Heimans, JanJ ; Reijneveld, JaapC ; Taphoorn, MartinJ B.

Background : during the end-of-life (EOL) phase of glioma patients, a rapid deterioration in neurological functioning may interfere with the oral intake of antiepileptic drugs (AEDs). We aimed to assess the feasibility of non-oral AED treatment in an out-of-hospital setting according to an expert-based guideline. Methods : Glioma patients with a history of epilepsy, in whom further antitumor therapy was considered to be no longer meaningful, were recruited at two Dutch hospitals. As soon as [...]

Menée aux Etats-Unis par enquête auprès de 405 oncologues médicaux, cette étude analyse leurs pratiques et leur participation dans des actions philanthropiques, notamment en invitant leurs patients à effectuer des dons

Oncologists' Experiences and Attitudes About Their Role in Philanthropy and Soliciting Donations From Grateful Patients

Walter, Jennifer K. ; Griffith, Kent A. ; Jagsi, Reshma

Purpose : Physician participation in philanthropy is important to marshal resources that allow hospitals to pursue their missions, but little is known about how physicians participate and their attitudes toward participation. Methods : To characterize philanthropic roles physicians play and their attitudes about participation and its ethical acceptability, medical oncologists affiliated with the 40 National Cancer Institute–designated comprehensive cancer centers were randomly sampled and [...]