A partir de données d'une enquête nationale, cette étude allemande évalue l'association entre une consommation d'alcool et le risque de cancer, notamment du côlon-rectum, du foie, du sein et des voies aérodigestives supérieures, pour l'année 2010

Incident cancers attributable to alcohol consumption in Germany, 2010

Wienecke, Antje ; Barnes, Benjamin ; Neuhauser, Hannelore ; Kraywinkel, Klaus

Purpose : Germany lacks an up-to-date assessment of the cancer burden attributable to alcohol. Therefore, cancer incidence attributable to this exposure was estimated for colorectal, liver, breast, and upper aerodigestive tract (UADT) cancer. Additionally, the impact of alcohol on UADT cancer was analyzed by smoking status, to account for synergistic interactions between these two risk factors. Methods : Alcohol consumption and smoking prevalence from a nationwide survey in Germany 2008–2011 [...]

Menée au Canada par questionnaire auprès de 1 181 patients et 5 039 témoins en population, cette étude évalue l'association entre une consommation de divers macronutriments (matières grasses, graisses saturées, cholestérol), le risque de cancer de l'estomac et du cardia gastrique

Macronutrient intake and stomach cancer

Hu, Jinfu ; La Vecchia, Carlo ; Negri, Eva ; de Groh, Margaret ; Morrison, Howard ; Mery, Les

Purpose : This study examines the association between intake of selected macronutrients and the risk of stomach cancer in a Northern American population. Methods : Mailed questionnaires were completed between 1994 and 1997 in eight Canadian provinces by 1,181 incident, histologically confirmed cases of stomach cancer and 5,039 population controls. Information on nutrient intake was obtained using a food frequency questionnaire. Odds ratios (ORs) and the corresponding 95 % confidence intervals [...]

A partir des données des registres américains des cancers et de données d'enquêtes, cette étude évalue l'association entre divers facteurs liés aux pratiques agricoles (achats de produits chimiques et de fertilisants) et le risque de cancer de la prostate, sur la période 2000-2010

Prostate cancer incidence and agriculture practices in Georgia, 2000–2010

Michael Welton ; Sara W. Robb ; Ye Shen ; Paul Guillebeau ; John Vena

Background:Georgia has prostate cancer incidence rates consistently above the national average. A notable portion of Georgia's economy is rooted in agricultural production, and agricultural practices have been associated with an increased risk of prostate cancer. Methods:Statistical analyses considered county age-adjusted prostate cancer incidence rates as the outcome of interest and three agricultural variables (farmland as percent of county land, dollars spent per county acre on agriculture [...]

A partir des données du registre ukrainien des cancers portant sur 13 203 participants âgés de moins de 18 ans au moment de l'accident de Chernobyl, cette étude évalue l'association entre une exposition à de hautes doses radioactives et le risque de cancers, autres que thyroïdiens

Non-thyroid cancer in Northern Ukraine in the post-Chernobyl period: Short report

Hatch, M. ; Ostroumova, E. ; Brenner, A. ; Federenko, Z. ; Gorokh, Y. ; Zvinchuk, O. ; Shpak, V. ; Tereschenko, V. ; Tronko, M. ; Mabuchi, K.

Abstract : The Chernobyl nuclear power plant accident in Ukraine in 1986 led to widespread radioactive releases into the environment – primarily of radioiodines and cesium – heavily affecting the northern portions of the country, with settlement-averaged thyroid doses estimated to range from 10 mGy to more than 10 Gy. The increased risk of thyroid cancer among exposed children and adolescents is well established but the impact of radioactive contamination on the risk of other types of cancer is [...]

Menée en Espagne à partir d'échantillons sanguins prélevés sur 603 patients atteints d'un cancer de l'estomac, 139 atteints d'un ulcère duodénal et 675 témoins, cette étude évalue notamment l'association entre un polymorphisme du gène PSCA et le risque de cancer de l'estomac

Association of PSCA rs2294008 gene variants with poor prognosis and increased susceptibility to gastric cancer and decreased risk of duodenal ulcer disease

García-González, María Asunción ; Bujanda, Luis ; Quintero, Enrique ; Santolaria, Santos ; Benito, Rafael ; Strunk, Mark ; Sopeña, Federico ; Thomson, Concha ; Pérez-Aisa, Angeles ; Nicolás-Pérez, David ; Hijona, Elizabeth ; Carrera-Lasfuentes, Patricia ; Piazuelo, Elena ; Jiménez, Pilar ; Espinel, Jesús ; Campo, Rafael ; Manzano, Marisa ; Geijo, Fernando ; Pellisé, Maria ; Zaballa, Manuel ; González-Huix, Ferrán ; Espinós, Jorge ; Titó, Llúcia ; Barranco, Luis ; Pazo-Cid, Roberto ; Lanas, Ángel

Two recent genome-wide association studies in Asians have reported the association between the PSCA (prostate stem cell antigen) rs2294008C>T gene polymorphism and two Helicobacter pylori infection-related diseases such as gastric cancer (GC) and duodenal ulcer (DU). Since rs2294008 allele frequencies differ notably among ethnicities, we aimed to assess the role of rs2294008 on the susceptibility to GC and DU in a Caucasian population in Spain. Moreover, the relevance of rs2294008 on GC [...]

Menée au Nigéria, au Cameroun et en Ouganda auprès de 1 995 cas et 2 631 témoins, cette étude évalue l'association entre des facteurs reproductifs, notamment le nombre de grossesses menées à terme, et le risque de cancer du sein

Breast cancer risk after full-term pregnancies among African women from Nigeria, Cameroon, and Uganda

Sighoko, Dominique ; Ogundiran, Temidayo ; Ademola, Adeyinka ; Adebamowo, Clement ; Chen, Lin ; Odedina, Stella ; Anetor, Imaria ; Ndom, Paul ; Gakwaya, Antony ; Ojengbede, Oladosu ; Huo, Dezheng ; Olopade, Olufunmilayo I.

BACKGROUND : The breast cancer (BC) risk profiles of African women differ significantly from those of women of European ancestry. African women are younger at the age of onset and tend to have high parity. The purpose of this study was to examine the relationship between full-term pregnancy (FTP) and the risk of BC. METHODS A case-control study was conducted among 1995 women with invasive BC and 2631 controls in Nigeria, Cameroon, and Uganda. Odds ratios (ORs) for individual ages at FTP [...]

A partir d'une revue systématique de la littérature (30 études prospectives, 22 320 cas, 6 445402 participantes), cette méta-analyse évalue l'association entre des facteurs anthropométriques (indice de masse corporelle, obésité, tour de taille, etc) et le risque de cancer de l'endomètre

Anthropometric factors and endometrial cancer risk: A systematic review and dose-response meta-analysis of prospective studies

Aune, D. ; Navarro Rosenblatt, D.A. ; Chan, D. S. M. ; Vingeliene, S. ; Abar, L. ; Vieira, A. R. ; Greenwood, D. C. ; Bandera, E. V. ; Norat, T.

Background : Greater body mass index has been convincingly related to increased endometrial cancer risk, however, whether adiposity earlier in life or abdominal fatness, is an independent risk factor and whether weight gain or greater height increases the risk is not clear. Methods : As part of the Continuous Update Project of the World Cancer Research Fund International we conducted a systematic review and meta-analysis of prospective studies of the association between anthropometric measures [...]