Menée aux Etats-Unis par enquête auprès de 58 585 survivants adultes d'un cancer, cette étude analyse leurs besoins et leur utilisation de services de soins de support en santé mentale, avant (2005) et après (2010) la mise en oeuvre de recommandations nationales relatives aux soins psychosociaux

Mental health needs and service use in a national sample of adult cancer survivors in the USA: has psychosocial care improved?

Whitney, Robin L. ; Bell, Janice F. ; Bold, Richard J. ; Joseph, Jill G.

Objective : This study aims to estimate and test temporal differences in mental health (MH) need and service use among adult cancer survivors nationally before and after important policy recommendations for psychosocial cancer care. Methods : Adults (n = 58,585) from the National Health Interview Survey, 2005 and 2010, were categorized as having (1) no chronic disease, (2) chronic disease other than cancer, (3) cancer without other chronic disease, and (4) cancer with other chronic disease. In [...]

Mené au Japon, cet essai de phase II analyse l'efficacité d'une thérapie à base d'aprépitant, de palonosetron et de déxamethasone pour prévenir les nausées et vomissements induits par une chimiothérapie à base de cisplatine chez des patientes atteintes d'un cancer gynécologique

Efficacy and safety of triple therapy with aprepitant, palonosetron, and dexamethasone for preventing nausea and vomiting induced by cisplatin-based chemotherapy for gynecological cancer: KCOG-G1003 phase II trial

Takeshima, Nobuhiro ; Matoda, Maki ; Abe, Masakazu ; Hirashima, Yasuyuki ; Kai, Kentaro ; Nasu, Kaei ; Takano, Masashi ; Furuya, Kenichi ; Sato, Seiya ; Itamochi, Hiroaki ; Tsubamoto, Hiroshi ; Hasegawa, Kosei ; Terao, Kiminari ; Otsuki, Takeo ; Kuritani, Keiko ; Ito, Kimihiko

Purpose : Prevention of chemotherapy-induced nausea and vomiting (CINV) is crucial for maintaining the quality of life of cancer patients. Female patients have been underrepresented in previous clinical studies of aprepitant or palonosetron. We performed a prospective multicenter study to investigate the efficacy and safety of triple therapy comprising these two agents and dexamethasone in female cancer patients receiving chemotherapy that included cisplatin (≥50 mg/m2). Methods : Aprepitant [...]

Menée sur des rats, cette étude américaine analyse l'efficacité d'un vasoconstricteur appliqué sur la peau pour prévenir une alopécie induite par la chimio ou la radiothérapie

A new strategy to prevent chemotherapy and radiotherapy-induced alopecia using topically applied vasoconstrictor

Soref, Cheryl M. ; Fahl, William E.

In a new strategy, we sought to determine whether topically applied vasoconstrictor, with its accompanying transient skin hypoxia and exclusion of systemic drug, would prevent or suppress radiotherapy or chemotherapy-induced alopecia. Topical vasoconstrictor was applied to 1-cm2 skin patches on the backs of 10-day-old rats and minutes later they received either 7.1 gray (Gy) whole-body radiation or systemic N-nitroso-N-methylurea (MNU) or Cytoxan. The degree of alopecia was scored 10 days later [...]

A partir des données de quatre registres australiens des cancers portant sur 696 survivants d'un cancer hématologique et âgés de 18 à 80 ans, cette étude transversale analyse les facteurs associés à leurs expériences et besoins en soins de support non satisfaits

Factors associated with haematological cancer survivors experiencing a high level of unmet need across multiple items of supportive care: a cross-sectional survey study

Hall, Alix ; D’Este, Catherine ; Tzelepis, Flora ; Lynagh, Marita ; Sanson-Fisher, Rob

Purpose : This study aimed to identify subgroups of haematological cancer survivors who report a “high/very high” level of unmet need on multiple (≥7) items of supportive care. Methods : Haematological cancer survivors, aged 18 to 80 years at recruitment were selected from four Australian state-based cancer registries. Eligible survivors were sent a survey containing the Survivor Unmet Needs Survey (SUNS). Logistic regression analysis was used to identify characteristics associated with [...]

Menée en Allemagne auprès de 3 289 patients atteints d'un cancer de la prostate, cette étude prospective multicentrique évalue la fatigue liée au cancer, avant et après une prostatectomie radicale

Cancer-related fatigue in patients before and after radical prostatectomy. Results of a prospective multi-centre study

Köhler, Norbert ; Gansera, Lutz ; Holze, Sigrun ; Friedrich, Michael ; Rebmann, Udo ; Stolzenburg, Jens-Uwe ; Truss, MichaelC ; Fahlenkamp, Dirk ; Scholz, Hans-Jörg ; Brähler, Elmar

Purpose : A multi-centre, longitudinal study was conducted to assess the prevalence of fatigue amongst men with localized prostate cancer, to describe several dimensions of fatigue and to explore the predictability of fatigue by psychological distress and physical function. Methods : The prevalence of fatigue was evaluated using the Multidimensional Fatigue Inventory in 329 prostate cancer patients before, 3, 6 and 12 months after surgery. Psychological distress was assessed using the Hospital [...]

Cette étude américaine fait le point sur les outils permettant d'évaluer la qualité de vie des patients atteints d'un cancer de la prostate

Quality-of-life assessment tools for men with prostate cancer

Bergman, Jonathan ; Laviana, Aaron

Quality-of-life assessment tools for men with prostate cancer have given patients and health-care providers a nuanced understanding not only of how long patients will survive, but also how well they will live. Health-related quality of life (HRQOL) addresses the entire spectrum of human experience, including daily necessities, interpersonal relationships, physical and mental health, illness, and professional and personal happiness. Developing an HRQOL instrument is a methodologically rigorous [...]

Menée aux Etats-Unis auprès de 398 dyades patients-aidants, cette étude évalue, en fonction du sexe et du type de cancer (côlon-rectum, poumon), l'association entre les symptômes de dépression et la qualité de vie chez des patients et chez leurs aidants familiaux

Effects of gender and depressive symptoms on quality of life among colorectal and lung cancer patients and their family caregivers

Kim, Youngmee ; van Ryn, Michelle ; Jensen, Roxanne E. ; Griffin, Joan M. ; Potosky, Arnold ; Rowland, Julia

Objective : Cancer patients and their family caregivers often report elevated levels of depressive symptoms, along with poorer mental and physical health (quality of life: QOL). Although the mutuality in distress between patients and their caregivers is relatively well known, unknown are the degree to which caregivers' depressive symptoms independently predict their patient's QOL and vice versa, and whether the relations vary by cancer type or gender. Methods : Colorectal or lung cancer [...]

Menée en Allemagne et couplée à une étude cas-témoins, cette étude de cohorte prospective analyse les facteurs associés à une fatigue persistante à long terme chez des survivantes d'un cancer du sein

Determinants of long-term fatigue in breast cancer survivors: results of a prospective patient cohort study

Schmidt, Martina E. ; Chang-Claude, Jenny ; Seibold, Petra ; Vrieling, Alina ; Heinz, Judith ; Flesch-Janys, Dieter ; Steindorf, Karen

Objective : Fatigue is among the most distressing symptoms across the breast cancer continuum. However, little is known about the factors contributing to long-term persisting fatigue. Therefore, we explored determinants of long-term physical, affective, and cognitive fatigue in a prospective cohort of breast cancer patients. Methods : Breast cancer patients recruited in a population-based case–control study (MARIE study) provided comprehensive data on sociodemographics, lifestyle, and [...]

Menée aux Pays-Bas auprès de 521 patientes ménopausées et atteintes d'un cancer du sein HR+, cette étude analyse l'association entre l'activité physique, la survie globale, la survie spécifique et le risque de récidive

Physical activity and survival of postmenopausal, hormone receptor–positive breast cancer patients: Results of the Tamoxifen Exemestane Adjuvant Multicenter Lifestyle study

de Glas, Nienke A. ; Fontein, Duveken B. Y. ; Bastiaannet, Esther ; Pijpe, Anouk ; Craen, Anton J. M. ; Liefers, Gerrit-Jan ; Nortier, Hans J. W. R. ; de Haes, Hanneke J. C. J. M. ; van de Velde, Cornelis J. J. ; van Leeuwen, Flora E.

BACKGROUND Physical activity has been related to improved breast cancer outcomes. Especially in the older breast cancer population, physical activity may be important because old age is associated with comorbidities and decreased physical function. The purpose of this study was to investigate the relation between physical activity and overall survival, breast cancer–specific survival, and recurrence in several age groups of postmenopausal breast cancer patients. METHODS The Tamoxifen Exemestane [...]

A partir des données de la cohorte "Childhood Cancer Survivor Study" portant sur 7 287 cas (âge médian : 36 ans) et 2 107 témoins (âge médian : 38 ans), cette étude analyse l'évolution du niveau d'activité physique chez des survivants d'un cancer de l'enfance

Decline in physical activity level in the Childhood Cancer Survivor Study cohort

Wilson, Carmen L. ; Stratton, Kayla ; Leisenring, Wendy M. ; Oeffinger, Kevin C. ; Nathan, Paul C. ; Wasilewski-Masker, Karen ; Hudson, Melissa M. ; Castellino, Sharon M. ; Stovall, Marilyn ; Armstrong, Gregory T. ; Brinkman, Tara M. ; Krull, Kevin R. ; Robison, Leslie L. ; Ness, Kirsten K.

Background: We aimed to identify demographic and health-related predictors of declining physical activity levels over a four year period among participants in the Childhood Cancer Survivor Study. Methods: Analyses included 7287 >5 year childhood cancer survivors and 2107 siblings who completed multiple follow-up questionnaires. Participants were classified as active if they met the Centers for Disease Control and Prevention guidelines for physical activity. Generalized linear models were used [...]

Menée aux Etats-Unis à partir des données d'un essai portant sur l'hypertension systolique chez des personnes âgées, cette étude évalue l'association entre une diminution rapide de la pression artérielle liée aux médicaments anti-hypertenseurs et la mortalité par cancer

Rapid Decreases in Blood Pressure From Antihypertensive Treatment were Associated with Increased Cancer Mortality in the Systolic Hypertension in the Elderly Program

Swerdel, Joel N. ; Janevic, Teresa M. ; Cabrera, Javier ; Cosgrove, Nora M. ; Sedjro, Jeanine E. ; Pressel, Sara L. ; Davis, Barry R. ; Kostis, John B.

Background: Research on the association between antihypertensive drug treatment (HTDT) and cancer is equivocal. We tested the hypothesis that large, rapid decreases in blood pressure following HTDT are associated with higher cancer mortality. Methods: Data from the Systolic Hypertension in the Elderly Program (SHEP) with 15-year cause-specific follow-up for mortality were used. We utilized changes from baseline in seated and standing systolic blood pressure (SBP) measurements at 3, 6, 9, and 12 [...]

Cette étude présente les projections d'incidence des cancers et de la mortalité spécifique jusqu'en 2030 aux Etats-Unis, et souligne l'importance grandissante des cancers de la thyroïde, du foie et du pancréas

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

Rahib, Lola ; Smith, Benjamin D. ; Aizenberg, Rhonda ; Rosenzweig, Allison B. ; Fleshman, Julie M. ; Matrisian, Lynn M.

Cancer incidence and deaths in the United States were projected for the most common cancer types for the years 2020 and 2030 based on changing demographics and the average annual percentage changes in incidence and death rates. Breast, prostate, and lung cancers will remain the top cancer diagnoses throughout this time, but thyroid cancer will replace colorectal cancer as the fourth leading cancer diagnosis by 2030, and melanoma and uterine cancer will become the fifth and sixth most common [...]

A partir des données de la cohorte "Childhood Cancer Survivor Study" portant sur 12 360 survivants à cinq ans d'un cancer pédiatrique et 4 023 témoins, cette étude analyse l'incidence de morbidités infectieuses et la mortalité liée aux infections

Infections among long-term survivors of childhood and adolescent cancer: A report from the Childhood Cancer Survivor Study

Perkins, Joanna L. ; Chen, Yan ; Harris, Anne ; Diller, Lisa ; Stovall, Marilyn ; Armstrong, Gregory T. ; Yasui, Yutaka ; Robison, Leslie L. ; Sklar, Charles A. ; on behalf of the Childhood Cancer Survivor, Study

BACKGROUND : Little is known about infections among adult survivors of childhood cancer. The authors report the occurrence of infections and risk factors for infections in a large cohort of survivors of childhood cancer. METHODS : The Childhood Cancer Survivor Study cohort was used to compare incidence rates of infections among 12,360 5-year survivors of childhood cancer with the rates of 4023 siblings. Infection-related mortality of survivors was compared with that of the US population. [...]

A partir des données d'un registre australien des cancers, cette étude analyse l'évolution de l'incidence du mélanome chez les adolescents et jeunes adultes (15-24 ans), ainsi que la survie, sur la période 1982-2010

Melanoma incidence trends and survival in adolescents and young adults in Queensland, Australia

Iannacone, Michelle R. ; Youlden, Danny R. ; Baade, Peter D. ; Aitken, Joanne F. ; Green, Adèle C.

Cutaneous melanoma is a relatively common cancer in adolescents and young adults in Australia, but detailed information about occurrence patterns and prognosis is limited. We evaluated incidence trends from 1982 to 2010 and recent survival rates in those aged 15–24 years in the state of Queensland. In situ and invasive melanoma cases were identified from the Queensland Cancer Registry. Incidence rates were age-standardised to the 2000 World population and trends calculated using joinpoint [...]

A partir des données de l'Organisation Mondiale de la Santé portant sur 65 populations vivant sur 6 continents, cette étude analyse les disparités géographiques dans l'évolution de la mortalité par cancer du poumon chez les femmes de 30 à 49 ans et de 50 à 74 ans, sur la période 2006-2010

International Variation in Lung Cancer Mortality Rates and Trends among Women

Torre, Lindsey A. ; Siegel, Rebecca L. ; Ward, Elizabeth M. ; Jemal, Ahmedin

Background: There is no recent comprehensive global analysis of lung cancer mortality in women. We describe contemporary mortality rates and trends among women globally. Methods: We used the World Health Organization's Cancer Mortality Database covering 65 populations on six continents to calculate age-standardized (1960 Segi world standard) lung cancer death rates during 2006 to 2010 and annual percent change in rates for available years from 1985 to 2011 and for the most recent five data [...]

A partir des données des registres américains des cancers portant sur 441 504 survivants d'un cancer de la prostate diagnostiqué entre 1992 et 2010, cette étude de cohorte en population analyse le risque de second cancer primitif, en fonction du critère ethnique et des traitements reçus

Risk of second primary tumors in men diagnosed with prostate cancer: A population-based cohort study

Davis, Elizabeth J. ; Beebe-Dimmer, Jennifer L. ; Yee, Cecilia L. ; Cooney, Kathleen A.

BACKGROUND The survival of men diagnosed with prostate cancer has improved over time, and the current 10-year relative survival rate is 99.7%. The long survival of patients with this common cancer raises questions about the risk of a second primary cancer and the need for continued surveillance. METHODS A population-based cohort of 441,504 men who were diagnosed with prostate cancer between 1992 and 2010 was identified from Surveillance, Epidemiology and End Results Program (SEER) data [...]

Menée aux Etats-Unis auprès de 164 cas et 182 témoins (âge supérieur à 60 ans), cette étude analyse la prévalence des déficiences cognitives chez des patientes atteintes d'un cancer du sein avant de recevoir une thérapie systémique

Cognitive Impairment in Older Patients With Breast Cancer Before Systemic Therapy: Is There an Interaction Between Cancer and Comorbidity?

Mandelblatt, Jeanne S. ; Stern, Robert A. ; Luta, Gheorghe ; McGuckin, Meghan ; Clapp, Jonathan D. ; Hurria, Arti ; Jacobsen, Paul B. ; Faul, Leigh Anne ; Isaacs, Claudine ; Denduluri, Neelima ; Gavett, Brandon ; Traina, Tiffany A. ; Johnson, Patricia ; Silliman, Rebecca A. ; Turner, R. Scott ; Howard, Darlene ; Van Meter, John W. ; Saykin, Andrew ; Ahles, Tim

Purpose : To determine if older patients with breast cancer have cognitive impairment before systemic therapy. Patients and Methods : Participants were patients with newly diagnosed nonmetastatic breast cancer and matched friend or community controls age > 60 years without prior systemic treatment, dementia, or neurologic disease. Participants completed surveys and a 55-minute battery of 17 neuropsychological tests. Biospecimens were obtained for APOE genotyping, and clinical data were [...]

A partir des données du registre californien des cancers portant sur 46 087 cas, cette étude analyse l'évolution du cancer de la thyroïde sur la période 1988-2009, en fonction des caractéristiques du patient, de la tumeur et de facteurs ethniques et socioéconomiques

Continued Rapid Increase in Thyroid Cancer Incidence in California: Trends by Patient, Tumor, and Neighborhood Characteristics

Horn-Ross, Pamela L. ; Lichtensztajn, Daphne Y. ; Clarke, Christina A. ; Dosiou, Chrysoula ; Oakley-Girvan, Ingrid ; Reynolds, Peggy ; Gomez, Scarlett Lin ; Nelson, David O.

Background: Thyroid cancer incidence is increasing worldwide. Incorporating 22 years of incidence data through 2009, we extend examination of these trends among a wide array of subgroups defined by patient (age, sex, race/ethnicity, and nativity), tumor (tumor size and stage), and neighborhood (socioeconomic status and residence in ethnic enclaves) characteristics, to identify possible reasons for this increase. Methods: Thyroid cancer incidence data on 10,940 men and 35,147 women were obtained [...]

Menée aux Etats-Unis auprès de 205 patients atteints d'un cancer de la vessie traité par cystectomie radicale, cette étude évalue l'association entre une sarcopénie, la mortalité spécifique et la survie globale

Sarcopenia in patients with bladder cancer undergoing radical cystectomy: Impact on cancer-specific and all-cause mortality

Psutka, Sarah P. ; Carrasco, Alonso ; Schmit, Grant D. ; Moynagh, Michael R. ; Boorjian, Stephen A. ; Frank, Igor ; Stewart, Suzanne B. ; Thapa, Prabin ; Tarrell, Robert F. ; Cheville, John C. ; Tollefson, Matthew K.

BACKGROUND The authors evaluated sarcopenia as a predictor of cancer-specific survival (CSS) and overall survival (OS) among patients with urothelial cancer of the bladder undergoing radical cystectomy (RC). METHODS The lumbar skeletal muscle index (SMI) of 205 patients treated with RC for urothelial cancer between 2000 and 2007 was measured. Sarcopenia was classified according to international consensus definitions (SMI of < 55 cm2/m2 for men and < 39 cm2/m2 for women). The CSS and OS were [...]

Menée en Suède par questionnaire auprès de 260 parents d'enfants ayant reçu une greffe de cellules souches hématopoïétiques, cette étude analyse les facteurs associés à leurs symptômes de nature psychologique (dépression, anxiété, burn-out, stress post-traumatique)

Patterns of psychological responses in parents of children that underwent stem cell transplantation

Riva, Roberto ; Forinder, Ulla ; Arvidson, Johan ; Mellgren, Karin ; Toporski, Jacek ; Winiarski, Jacek ; Norberg, Annika Lindahl

Objective : Hematopoietic stem cell transplantation (HSCT) is curative in several life-threatening pediatric diseases but may affect children and their families inducing depression, anxiety, burnout symptoms, and post-traumatic stress symptoms, as well as post-traumatic growth (PTG). The aim of this study was to investigate the co-occurrence of different aspects of such responses in parents of children that had undergone HSCT. Methods : Questionnaires were completed by 260 parents (146 mothers [...]

Menée en Suède auprès de 174 patients atteints de cancer et traités dans des unités de soins palliatifs, cette étude analyse les facteurs associés à leurs perceptions vis-à-vis du soutien reçu de la part des membres de leur famille

Patients' sense of support within the family in the palliative care context: what are the influencing factors?

Milberg, Anna ; Wåhlberg, Rakel ; Krevers, Barbro

Objective : Mutual support within the family is of great importance to maintain its proper functioning. The study aim, which was based on a family system approach, was to evaluate which variables are associated with patients' sense of support within the family in the palliative care context. Methods : We recruited 174 adult patients (65% of those eligible) from six palliative home care units, who had non-curable disease with an expected short-term survival, such as disseminated cancer or [...]

Menée en Suède auprès de 810 survivantes d'un cancer diagnostiqué entre 2003 et 2007 (âge : de 18 à 45 ans), cette étude analyse leurs projets de maternité, de 3 à 7 ans après un diagnostic de cancer, ainsi que leurs difficultés à mener à terme leur grossesse et leur détresse psychologique liée à l'infertilité

Desire for children, difficulties achieving a pregnancy, and infertility distress 3 to 7 years after cancer diagnosis

Armuand, GabrielaM ; Wettergren, Lena ; Rodriguez-Wallberg, KennyA ; Lampic, Claudia

The aim was to investigate desire for children, difficulties achieving a pregnancy, and infertility distress among survivors 3 to 7 years after cancer treatment in reproductive age. Methods : Cancer survivors were identified in national population-based cancer registries. Eligible subjects presented with selected cancer diagnoses between 2003 and 2007 between the ages of 18 to 45. A postal questionnaire including study-specific questions, the Short-Form 36 Health Survey and the Fertility [...]

Menée en Australie auprès de 21 patients atteints d'un cancer localisé de la prostate et 14 partenaires de vie, cette étude qualitative analyse leurs expériences et leurs préférences thérapeutiques, qu'il s'agisse d'une surveillance active ou de traitements radicaux (prostatectomie, radiothérapie externe, curiethérapie)

‘What is this active surveillance thing?’ Men's and partners' reactions to treatment decision making for prostate cancer when active surveillance is the recommended treatment option

O'Callaghan, Clare ; Dryden, Tracey ; Hyatt, Amelia ; Brooker, Joanne ; Burney, Sue ; Wootten, Addie C. ; White, Alan ; Frydenberg, Mark ; Murphy, Declan ; Williams, Scott ; Schofield, Penelope

Objective : In the past decade, localised prostate cancer (LPC) management has been shifting from three radical treatment options (radical prostatectomy, external beam radiotherapy, or brachytherapy) to also include active surveillance (AS). This study examines men with LPC and partners' experiences of choosing between AS and radical treatments, and their experiences of AS when selected. Methods : A qualitative descriptive research design was used. Interviewed participants were men, and [...]

Menée à Taïwan auprès de 124 patientes atteintes d'un cancer du sein, cette étude longitudinale analyse l'évolution de leurs comportements d'adaptation (croissance post-traumatique) durant la première année après un traitement chirurgical

Identification of posttraumatic growth trajectories in the first year after breast cancer surgery

Wang, Ashley Wei-Ting ; Chang, Cheng-Shyong ; Chen, Shou-Tung ; Chen, Dar-Ren ; Hsu, Wen-Yau

Background : Empirical studies of the relationship between posttraumatic growth (PTG) and adjustment outcomes reveal a fairly inconclusive picture. We argue that the inconsistent findings are likely due to the heterogeneity of the PTG experience over time. In this regard, we predicted that individuals with different PTG trajectories vary in the level of adjustment and the correlational patterns between PTG and adjustment. Methods : Participants were 124 Taiwanese women who underwent surgery for [...]

Menée par enquête téléphonique auprès de 696 femmes âgées de 21 à 85 ans effectuant un test génétique pour une mutation BRCA1 ou BRCA2, cette étude américaine analyse leurs intentions relatives à une chirurgie préventive (mastectomie ou ovariectomie prophylactiques)

Intentions for risk-reducing surgery among high-risk women referred for BRCA1/BRCA2 genetic counseling

Tong, Angie ; Kelly, Scott ; Nusbaum, Rachel ; Graves, Kristi ; Peshkin, Beth N. ; Valdimarsdottir, Heiddis B. ; Wood, Marie ; McKinnon, Wendy ; Garber, Judy ; McCormick, Shelley R. ; Jandorf, Lina ; Schwartz, Marc D.

Objective : Genetic testing for breast and ovarian cancer susceptibility is now part of routine clinical practice. Although rates of risk-reducing surgery following genetic testing have been increasing, little is known about attitudes toward risk-reducing surgery in women prior to genetic counseling and testing. This study examines correlates of patient intentions to undergo risk-reducing mastectomy (RRM) and risk-reducing oophorectomy (RRO). Methods : Participants were 696 women, ages 21–85, [...]

Menée aux Etats-Unis auprès de 112 patientes atteintes d'un cancer du sein et recevant une hormonothérapie adjuvante, cette étude analyse l'association entre leurs symptômes physiques, leur sentiment d'auto-efficacité pour les gérer, ainsi que leur bien-être fonctionnel, émotionnel et social

Self-efficacy for coping with symptoms moderates the relationship between physical symptoms and well-being in breast cancer survivors taking adjuvant endocrine therapy

Shelby, RebeccaA ; Edmond, SaraN ; Wren, AnavaA ; Keefe, FrancisJ ; Peppercorn, JeffreyM ; Marcom, PaulK ; Blackwell, KimberlyL ; Kimmick, GretchenG

Purpose : This study examined the relationships between physical symptoms, self-efficacy for coping with symptoms, and functional, emotional, and social well-being in women who were taking adjuvant endocrine therapy for breast cancer. Methods : One hundred and twelve women who were taking adjuvant endocrine therapy (tamoxifen or an aromatase inhibitor) for breast cancer completed measures of physical symptoms, self-efficacy for coping with symptoms, and functional, social, and emotional [...]

A partir d'une revue systématique de la littérature (69 études), cette étude fait le point sur l'utilisation des différents médias sociaux dans le champ de l'oncologie et leur impact sur les comportements de santé

Use and Taxonomy of Social Media in Cancer-Related Research: A Systematic Review

Koskan, Alexis ; Klasko, Lynne ; Davis, Stacy N. ; Gwede, Clement K. ; Wells, Kristen J. ; Kumar, Ambuj ; Lopez, Natalia ; Meade, Cathy D.

Little is known about how social media are used in cancer care. We conducted a systematic review of the use and taxonomy of social media in cancer-related studies, in PubMed, Web of Knowledge, CINAHL, and Google Scholar. We located 1350 articles published through October 2013; 69 met study inclusion criteria. Early research (1996?2007) was predominantly descriptive studies of online forums. Later, researchers began analyzing blogs, videos shared on YouTube, and social networking sites. Most [...]

A partir d'une revue de la littérature, cette étude fait le point sur l'utilisation de la sédation palliative dans les soins de fin de vie pour soulager la souffrance des patients atteints d'un cancer de stade avancé

Palliative sedation for intolerable suffering

Maltoni, Marco ; Scarpi, Emanuela ; Nanni, Oriana

Purpose of review: The purpose of this review is to provide an update on palliative sedation in palliative and end-of-life care. Palliative sedation is the medical procedure used to deal with refractory symptoms in advanced cancer patients when all other specific approaches have failed. Recent findings: Palliative sedation, in the strictest sense of the term, is a proportionate (proportionate palliative sedation, PPS) and intrinsically variable procedure used on an individual basis to relieve [...]

Menée aux Etats-Unis, cette étude analyse les problématiques éthiques, juridiques et psychosociales associées à l'usage de tests génétiques en oncologie

“Would you test your children without their consent?” and other sticky dilemmas in the field of cancer genetic testing

Brierley, KarinaL ; Bonadies, DanielleC ; Moyer, Anne ; Matloff, EllenT

Cancer genetic testing is surrounded by myriad ethical, legal, and psychosocial implications which are being revisited as testing expands into an everyday practice and into more complicated areas like whole exome and direct-to-consumer testing. We chose to survey cancer genetic counselors and physicians from a wide range of non-genetics specialties to determine what they would do if faced with the complex decisions associated with cancer genetic testing, how their views compare, and how they [...]