A partir d'une revue systématique de la littérature (34 études), cette étude analyse une stratégie destinée à développer les capacités des patients atteints de cancer à se sentir acteurs de la prise en charge de leur douleur

Patient empowerment in cancer pain management: an integrative literature review

te Boveldt, Nienke ; Vernooij-Dassen, Myrra ; Leppink, Irene ; Samwel, Han ; Vissers, Kris ; Engels, Yvonne

Objective : More than 50% of patients with cancer experience pain. Patient empowerment has been highlighted as central to success in pain management. Up to now, no clear model for this patient group exists, yet several strategies to empower patients have been used in clinical practice. This review examines how empowerment or related concepts have been described in relation to pain management in patients with cancer. With the help of a conceptual model, recommendations for clinical practice are [...]

A partir des données d'un registre australien des cancers portant sur 410 participants, cet essai randomisé évalue l'efficacité d'une intervention téléphonique visant à limiter les comportements sédentaires chez des survivants d'un cancer colorectal

A randomized controlled trial of a multiple health behavior change intervention delivered to colorectal cancer survivors

Lynch, Brigid M. ; Courneya, Kerry S. ; Sethi, Parneet ; Patrao, Tania A. ; Hawkes, Anna L.

BACKGROUND Sedentary behavior may independently contribute to morbidity and mortality among survivors of colorectal cancer. In the current study, the authors assessed whether a telephone-delivered multiple health behavior change intervention had an effect on the sedentary behavior of recently diagnosed colorectal cancer survivors. METHODS A total of 410 participants were recruited through the Queensland Cancer Registry and randomized to the health coaching (intervention) or usual-care (control) [...]

Mené aux Etats-Unis auprès de 68 dyades mères-filles (136 participantes), cet essai randomisé analyse l'efficacité d'une intervention visant à promouvoir la perte de poids, chez des survivantes d'un cancer du sein et chez leurs filles en surcharge pondérale

Daughters and Mothers Against Breast Cancer (DAMES): Main outcomes of a randomized controlled trial of weight loss in overweight mothers with breast cancer and their overweight daughters

Demark-Wahnefried, Wendy ; Jones, Lee W. ; Snyder, Denise C. ; Sloane, Richard J. ; Kimmick, Gretchen G. ; Hughes, Daniel C. ; Badr, Hoda J. ; Miller, Paige E. ; Burke, Lora E. ; Lipkus, Isaac M.

BACKGROUND Few studies to date have used the cancer diagnosis as a teachable moment to promote healthy behavior changes in survivors of cancer and their family members. Given the role of obesity in the primary and tertiary prevention of breast cancer, the authors explored the feasibility of a mother-daughter weight loss intervention. METHODS A randomized controlled trial of a mailed weight loss intervention was undertaken among 68 mother-daughter dyads (n = 136), each comprised of a survivor of [...]

Menée aux Etats-Unis auprès de 13 901 participants âgés de 45 à 64 ans, cette étude de cohorte évalue l'association entre l'indice de masse corporelle au début de l'âge adulte, des changements de poids ultérieurs et le risque de cancer

Body mass index at early adulthood, subsequent weight change and cancer incidence and mortality

Han, Xuesong ; Stevens, June ; Truesdale, Kimberly P. ; Bradshaw, Patrick T. ; Kucharska-Newton, Anna ; Prizment, Anna E. ; Platz, Elizabeth A. ; Joshu, Corinne E.

Obesity later in adulthood is associated with increased risks of many cancers. However, the effect of body fatness in early adulthood, and change in weight from early to later adulthood on cancer risk later in life is less clear. We used data from 13,901 people aged 45–64 in the Atherosclerosis Risk in Communities cohort who at baseline (1987–1989) self-reported their weight at the age of 25 and had weight and height measured. Incident cancers were identified through 2006 and cancer deaths were [...]

A partir d'une revue systématique de la littérature (23 essais randomisés, 13 909 participants), cette étude présente divers scénarii permettant d'estimer le temps de survie chez des patients atteints d'un cancer de la prostate résistant à la castration et commençant un traitement systémique

Estimating scenarios for survival time in men starting systemic therapies for castration-resistant prostate cancer: A systematic review of randomised trials

West, T. A. ; Kiely, B. E. ; Stockler, M. R.

Background : We sought to estimate worst-case, typical and best-case scenarios for survival in men starting systemic therapies for castration resistant prostate cancer (CRPC). Methods : We sought randomised phase 3 trials of systemic therapies for CRPC and recorded the following percentiles (represented scenario) from Kaplan–Meier overall survival (OS) curves: 90th (worst-case), 75th (lower-typical), 50th (median), 25th (upper-typical) and 10th (best-case). We determined the accuracy of using [...]

Menée en Suède auprès de 4 376 patients atteints d'un cancer de la prostate localisé et diagnostiqué entre 1997 et 2002, cette étude de cohorte analyse l'association entre l'indice de masse corporelle au moment du diagnostic, les changements de poids ultérieurs et la mortalité spécifique

Body mass index and weight change in men with prostate cancer: progression and mortality

Bonn, StephanieE ; Wiklund, Fredrik ; Sjölander, Arvid ; Szulkin, Robert ; Stattin, Pär ; Holmberg, Erik ; Gronberg, Henrik ; Bälter, Katarina

Purpose: Body mass index (BMI) is a modifiable lifestyle factor that has been associated with an increased risk of fatal prostate cancer and biochemical recurrence. The main purpose of the present study was to investigate the association between the exposure BMI at the time of a prostate cancer diagnosis and weight change after diagnosis, and the outcomes of prostate cancer progression and mortality in a large cohort study. Methods : Data from 4,376 men diagnosed with clinically localized [...]

A partir des données du registre néerlandais des cancers portant sur 137 030 survivants d'un cancer colorectal diagnostiqué entre 1989 et 2008, cette étude analyse l'évolution de la survie en fonction de l'âge et du stade de la tumeur au diagnostic

Conditional survival for long-term colorectal cancer survivors in the Netherlands: who do best?

van Erning, F. N. ; van Steenbergen, L. N. ; Lemmens, V. E. P. P. ; Rutten, H. J. T. ; Martijn, H. ; van Spronsen, D. J. ; Janssen-Heijnen, M. L. G.

Aim : With the increase in the number of long-term colorectal cancer (CRC) survivors, there is a growing need for subgroup-specific analysis of conditional survival. Methods : All 137,030 stage I–III CRC patients diagnosed in the Netherlands between 1989 and 2008 aged 15–89 years were selected from the Netherlands Cancer Registry. We determined conditional 5-year relative survival rates, according to age, subsite and tumour stage for each additional year survived up to 15 years after diagnosis [...]

A partir des données des registres américains des cancers portant sur 6 432 patients atteints d'un cancer du rectum diagnostiqué entre 1998 et 2007, cette étude analyse l'évolution de leur survie après un traitement chirurgical, en prenant en compte les caractéristiques de l'hôpital et celles du chirurgien

Patient survival after surgical treatment of rectal cancer: Impact of surgeon and hospital characteristics

Etzioni, David A. ; Young-Fadok, Tonia M. ; Cima, Robert R. ; Wasif, Nabil ; Madoff, Robert D. ; Naessens, James M. ; Habermann, Elizabeth B.

BACKGROUND Surgeon and hospital factors are associated with the survival of patients treated for rectal cancer. The relative contribution of each of these factors toward determining outcomes is poorly understood. METHODS We used data from the Surveillance, Epidemiology, and End Results–Medicare database to analyze the outcomes of patients aged 65 years and older undergoing operative treatment for nonmetastatic rectal cancer, diagnosed in the United States between 1998 and 2007. These data were [...]

A partir des données de 18 registres américains des cancers et du système "Behavioral Risk Factor Surveillance System", cette étude ré-évalue l'incidence du cancer du col de l'utérus en fonction de l'âge et de l'appartenance ethnique en prenant en compte la prévalence des hystérectomies, sur la période 2000 à 2009

Increased age and race-specific incidence of cervical cancer after correction for hysterectomy prevalence in the United States from 2000 to 2009

Rositch, Anne F. ; Nowak, Rebecca G. ; Gravitt, Patti E.

BACKGROUND Invasive cervical cancer is thought to decline in women over 65 years old, the age at which cessation of routine cervical cancer screening is recommended. However, national cervical cancer incidence rates do not account for the high prevalence of hysterectomy in the United States. METHODS Using estimates of hysterectomy prevalence from the Behavioral Risk Factor Surveillance System (BRFSS), hysterectomy-corrected age-standardized and age-specific incidence rates of cervical cancer [...]

Menée en Corée auprès de 136 dyades de patients atteints d'un cancer de stade avancé et d'aidants familiaux, cette étude analyse les connaissances des aidants relatives à la progression de la maladie ainsi que l'impact de leurs comportements pendant la chimiothérapie sur la qualité de vie du patient

Family caregivers' awareness of illness and attitude toward disclosure during chemotherapy for advanced cancer

Kim, Soyeun ; Ko, Youngjin ; Kwon, Sinyoung ; Shin, Dong-Yeop ; Kim, Cheol Hyeon ; Yang, Sung Hyun ; Cho, Seong-Jin ; Na, Im Il

Objective : We investigated family caregivers' awareness of disease status and attitude toward disclosure of disease progression compared with those of cancer patients and explored the potential association between family caregivers' attitudes and patients' quality of life (QOL). Methods : We carried out a survey using self-administered questionnaires answered by pairs of family caregivers and patients diagnosed with advanced cancer (n = 136 pairs). To assess patients' QOL, we used the European [...]

Menée aux Etats-Unis auprès de 50 dyades parents-enfants (enfants âgés de 7 à 19 ans), cette étude analyse l'association entre le stress parental et les morbidités neurocognotives et psychosociales chez des enfants atteints de leucémie ou de lymphome

Parental stress predicts functional outcome in pediatric cancer survivors

Hile, Sarah ; Erickson, Sarah J. ; Agee, Brittany ; Annett, Robert D.

Background : Childhood cancer survivors are at risk for long-term neurocognitive and psychosocial morbidities. Research has seldom examined the relationship between these morbidities; thus, little empirical evidence exists concerning overall salience and how morbidities converge to impair day-to-day functioning. An increased understanding of functional impairment resulting from the pediatric cancer experience can inform early risk identification as well as sources for intervention. The purpose [...]

A partir d'une revue systématique de la littérature (18 études qualitatives), cette étude analyse les motivations et préférences des patients atteints de cancer relatives à la recherche d'informations sur la maladie en dehors des consultations médicales

Information seeking and avoidance throughout the cancer patient journey: two sides of the same coin? A synthesis of qualitative studies

Germeni, Evi ; Schulz, Peter J.

Objective : Understanding what motivates patients to seek or avoid information beyond the medical consultation is essential for effective information provision that will be relevant to patients' needs and preferences. We conducted a synthesis of published qualitative research to provide insight into patients' motivations for cancer information seeking and avoidance. Methods : We searched five electronic databases: Medline, CINAHL, PsycINFO, Communication and Mass Media Complete, and [...]

Menée au Royaume-Uni auprès de 74 patients atteints de cancer et âgés de 12 à 18 ans, cette étude transversale multicentrique analyse les facteurs médicaux, psychologiques, et démographiques associés à une détresse psychologique avant la fin d'une période de cinq ans

Psychological, demographic, illness and treatment risk factors for emotional distress amongst paediatric oncology patients prior to reaching 5-year survivorship status

Canning, S. ; Bunton, P. ; Talbot Robinson, L.

Objectives : Studies assessing emotional distress severity of paediatric oncology patients prior to reaching 5-year survivorship status have produced inconsistent findings. This cross-sectional multi-centre study aimed to determine psychological, demographic, illness and treatment risk factors for emotional distress in this population. Methods : Paediatric oncology patients (n = 74), aged 12–18 years, completed the Paediatric Index of Emotional Distress, Self-Description Questionnaire and [...]

A partir des données du registre néerlandais des cancers portant sur 489 patients atteints d'un lymphome hodgkinien ou d'un lymphome diffus à grandes cellules B diagnostiqué de 1999 à 2010, cette étude analyse l'évolution de la prévalence de symptômes d'anxiété et de dépression en fonction de différentes catégories d'âge

The course of anxiety and depression for patients with Hodgkin’s lymphoma or diffuse large B cell lymphoma: a longitudinal study of the PROFILES registry

Oerlemans, Simone ; Mols, Floortje ; Nijziel, MartenR ; Zijlstra, WobbeP ; Coebergh, JanWillemW ; Poll-Franse, LonnekeV

Purpose : The purpose of this study is to prospectively assess anxiety and depression among patients with Hodgkin lymphoma (HL) and diffuse large B cell lymphoma (DLBCL). Also, to compare its prevalence with a normative population, identify subgroups with more anxiety and depression, and assess its impact on health-related quality of life (HRQoL). Methods : The population-based Eindhoven Cancer Registry was used to select patients diagnosed with HL or DLBCL from 1999 to 2010, 489 responded [...]

A partir d'une revue systématique de la littérature (17 études), cette étude analyse le ressenti des hommes face à la mastectomie de leur partenaire

A systematic review of men's experiences of their partner's mastectomy: coping with altered bodies

Rowland, Emma ; Metcalfe, Alison

Objective : To explore men's experiences of their partner's altered physique and body image as a result of mastectomy and subsequent reconstructive surgeries. Design : A systematic review of qualitative and mixed-methods studies. Data sources Ovid, EBSCOhost, Web of science, SCOPUS and ASSIA ProQuest databases were searched using 1) truncations of breast cancer, hereditary breast cancer and BRCA 2) words relating to partner relationships; spouse, husband, partner, men and couple 3) breast [...]

Menée aux Etats-Unis à partir des données portant sur 795 patients, cette étude analyse les coûts associés à une greffe allogénique de cellules souches hématopoïétiques utilisant un conditionnement à intensité réduite

Costs of Allogeneic Hematopoietic Cell Transplantation Using Reduced Intensity Conditioning Regimens

Khera, Nandita ; Emmert, Amy ; Storer, Barry E. ; Sandmaier, Brenda M. ; Alyea, Edwin P. ; Lee, Stephanie J.

Reduced intensity conditioning (RIC) regimens have allowed older patients and those with comorbidities to receive hematopoietic cell transplantation (HCT). We analyzed medical costs from the beginning of conditioning to 100 days after HCT for 484 patients and up to 2 years for 311 patients who underwent a RIC HCT at two institutions from January 2008 to December 2010. Multiple linear regression was used to analyze the association between clinical variables, center effect, and costs. Patient and [...]

Menée aux Etats-Unis auprès de 70 participants, cette étude analyse les problématiques liées à la décision thérapeutique chez des patients socioéconomiquement défavorisés et atteints d'un cancer de la prostate récemment diagnostiqué

Decisional Conflict in Economically Disadvantaged Men With Newly Diagnosed Prostate Cancer

Kaplan, Alan L. ; Crespi, Catherine M. ; Saucedo, Josemanuel D. ; Connor, Sarah E. ; Litwin, Mark S. ; Saigal, Christopher S.

BACKGROUND Decisional conflict is a source of anxiety and stress for men diagnosed with prostate cancer given uncertainty surrounding myriad treatment options. Few data exist to help clinicians identify which patients are at risk for decisional conflict. The purpose of this study was to examine factors associated with decisional conflict in economically disadvantaged men diagnosed with prostate cancer before any treatment choices were made. METHODS A total of 70 men were surveyed at a Veterans [...]

Menée aux Etats-Unis par enquête auprès de 77 participants, cette étude transversale analyse la formation professionnelle des médecins généralistes en matière de prise en charge et de suivi de leurs patients ayant été traités pour un cancer

Cancer survivorship training: a pilot study examining the educational gap in primary care medicine residency programs

Susanibar, Sandra ; Thrush, CarolR ; Khatri, Nudrat ; Hutchins, LauraF

Background: Cancer survivors need high-quality follow-up care that addresses long-term problems related to cancer and their treatment. With growing numbers of cancer patients transitioning from oncological treatment to survivorship care, primary care physicians (PCPs) will play a major role in the delivery of survivorship care. Objective : This pilot study was undertaken to provide initial insights into internal medicine (IM) and family medicine (FM) residents’ educational experience, training, [...]