Menée en Allemagne auprès de 40 patients atteints de cancer, cette étude analyse les effets de la pratique de la danse sur leur fatigue et leur qualité de vie pendant les traitements

Effect of dance on cancer-related fatigue and quality of life

Sturm, Isrid ; Baak, Johanna ; Storek, Benjamin ; Traore, Annette ; Thuss-Patience, Peter

Purpose : Cancer-related fatigue is a multidimensional symptom with an underestimated prevalence and severity in cancer patients. The aim of the study was to evaluate the effect of dance as a holistic sportive activity in cancer patients under active anticancer treatment with fatigue as endpoint. Patients and methods : Forty patients under active anticancer treatment (adjuvant (25), palliative (11) or neoadjuvant (4)) with moderate or severe fatigue (≥4 on the visual analogue scale) were [...]

Menée aux Etats-Unis auprès de 135 patients atteints d'un cancer de stade avancé et inclus dans un essai randomisé, cette étude analyse l'efficacité d'une intervention pédagogique sur la prise en charge de la douleur pour améliorer les prescriptions médicamenteuses

A pathway linking patient participation in cancer consultations to pain control

Street, Richard L. ; Tancredi, Daniel J. ; Slee, Christina ; Kalauokalani, Donna K. ; Dean, Dionne Evans ; Franks, Peter ; Kravitz, Richard L.

Objective : To test a pathway through which a tailored, pain management education–coaching intervention could contribute to better cancer pain control through the effects of patients' communication about pain on physician prescribing of pain medication. Methods : Secondary analysis of data from a randomized controlled trial that tested the effects of a tailored education–coaching intervention on pain control for patients with advanced cancer. The current analysis focused on a subset of the [...]

Menée en Allemagne auprès de 247 patients ayant reçu une greffe allogénique de cellules souches hématopoïétiques, cette étude prospective analyse la prévalence de leurs symptômes neuromusculaires

Neuromuscular complications after hematopoietic stem cell transplantation

Koeppen, Susanne ; Thirugnanasambanthan, Abhiyrahmi ; Koldehoff, Michael

Purpose : The aim of this study was to analyze the occurrence of neuromuscular symptoms in recipients of allogeneic hematopoietic stem cell transplantation (HSCT) for treatment of malignant hematopoietic disease. Methods : Among 247 outpatients after allogeneic HSCT, we conducted a prospective non-interventional study between July 2011 and August 2013. During follow-up visits, clinical and electrophysiological findings were correlated to the presence of autoantibodies/alloantibodies and to [...]

A partir d'une revue de la littérature, cette étude américaine plaide pour le développement des soins dentaires et buccaux, pour la prévention et/ou le traitement des maladies buccales liées aux traitements chez les patients atteints de cancer

Appropriate and necessary oral care for people with cancer: guidance to obtain the right oral and dental care at the right time

Epstein, JoelB ; Güneri, Pelin ; Barasch, Andrei

Purpose : The identification of experienced and knowledgeable dental specialists to provide appropriate oral care for cancer patients, as well as the integration of this care within general oncology management, may be a challenge. This paper discusses the general and additional requirements for dental care providers to support the cancer patient and provide prevention and/or treatment for oral complications of cancer therapy. Methods : We performed a literature review of specific issues [...]

Menée aux Etats-Unis auprès de 103 enfants atteints d'une leucémie myéloïde aiguë, cette étude analyse l'efficacité et les effets secondaires d'une utilisation prophylactique d'antibiotiques pour prévenir les éventuelles complications infectieuses induites par une chimiothérapie intensive

Feasibility, efficacy, and adverse effects of outpatient antibacterial prophylaxis in children with acute myeloid leukemia

Inaba, Hiroto ; Gaur, Aditya H. ; Cao, Xueyuan ; Flynn, Patricia M. ; Pounds, Stanley B. ; Avutu, Viswatej ; Marszal, Lindsay N. ; Howard, Scott C. ; Pui, Ching-Hon ; Ribeiro, Raul C. ; Hayden, Randall T. ; Rubnitz, Jeffrey E.

BACKGROUND : Intensive chemotherapy for pediatric acute myeloid leukemia incurs the risk of infectious complications, but the benefits of antibiotic prophylaxis remain unclear. METHODS : In the current study, among 103 children treated on the AML02 protocol between October 2002 and October 2008 at St. Jude Children's Research Hospital, the authors retrospectively assessed the effect of antibiotic prophylaxis on the frequency of febrile neutropenia, clinically or microbiologically confirmed [...]

Menée par questionnaire auprès de 1 019 patients atteints d'un cancer du rectum diagnostiqué entre 2000 et 2009, cette étude néerlandaise analyse les effets physiques et psychiques d'une stomie

Living with the physical and mental consequences of an ostomy: a study among 1–10-year rectal cancer survivors from the population-based PROFILES registry

Mols, Floortje ; Lemmens, Valery ; Bosscha, Koop ; van den Broek, Wim ; Thong, Melissa S. Y.

Background : This study examined the physical and mental consequences of an ostomy among 1–10-year rectal cancer survivors. Methods : Patients with rectal cancer diagnosed from 2000 to 2009, as registered in the population-based Eindhoven Cancer Registry, received a questionnaire on quality of life (QOL; EORTC QLQ-C30), disease-specific health status (EORTC QLQ-CR38), depression and anxiety (HADS), illness perceptions (Brief Illness Perception Questionnaire), and health care utilization; 76% [...]

A partir des données de 11 registres allemands des cancers, cette étude analyse et compare, dans les zones urbaines et rurales, l'évolution de la survie des patients atteints de cancer, sur la période 1997-2006

Survival of cancer patients in urban and rural areas of Germany—A comparison

Nennecke, Alice ; Geiss, Karla ; Hentschel, Stefan ; Vettorazzi, Eik ; Jansen, Lina ; Eberle, Andrea ; Holleczek, Bernd ; Gondos, Adam ; Brenner, Hermann

Background : Cancer care services including cancer prevention activities are predominantly localised in central cities, potentially causing a heterogeneous geographic access to cancer care. The question of an association between residence in either urban or rural areas and cancer survival has been analysed in other parts of the world with inconsistent results. This study aims at a comparison of age-standardised 5-year survival of cancer patients resident in German urban and rural regions using [...]

Menée en Suède, cette étude en population (7 109 327 hommes, 6 958 714 femmes) analyse l'évolution de la mortalité par cancer, par localisation et en fonction du pays d'origine, de la tranche d'âge, du sexe et du statut socioéconomique, sur la période 1961-2009

Cancer Mortality by Country of Birth, Sex, and Socioeconomic Position in Sweden, 1961–2009

Abdoli, Gholamreza ; Bottai, Matteo ; Moradi, Tahereh

In 2010, cancer deaths accounted for more than 15% of all deaths worldwide, and this fraction is estimated to rise in the coming years. Increased cancer mortality has been observed in immigrant populations, but a comprehensive analysis by country of birth has not been conducted. We followed all individuals living in Sweden between 1961 and 2009 (7,109,327 men and 6,958,714 women), and calculated crude cancer mortality rates and age-standardized rates (ASRs) using the world population for [...]

A partir des données du registre suédois du mélanome portant sur 27 235 patients atteints d'un mélanome cutané malin invasif diagnostiqué entre 1990 et 2007, cette étude en population évalue l'association entre le fait de vivre en couple ou non, le stade de la maladie au diagnostic et la survie

Later Stage at Diagnosis and Worse Survival in Cutaneous Malignant Melanoma Among Men Living Alone: A Nationwide Population-Based Study From Sweden

Eriksson, Hanna ; Lyth, Johan ; Månsson-Brahme, Eva ; Frohm-Nilsson, Margareta ; Ingvar, Christian ; Lindholm, Christer ; Naredi, Peter ; Stierner, Ulrika ; Carstensen, John ; Hansson, Johan

Purpose : To investigate the association between cohabitation status, clinical stage at diagnosis, and disease-specific survival in cutaneous malignant melanoma (CMM). Methods : This nationwide population-based study included 27,235 patients from the Swedish Melanoma Register diagnosed with a primary invasive CMM between 1990 and 2007 and linked data to nationwide, population-based registers followed up through 2012. Results : After adjustment for age at diagnosis, level of education, living [...]

A partir des données du registre italien des mésothéliomes portant sur la période 1980-2012 (997 cas), cette étude évalue l'incidence du mésothéliome malin familial en Italie centrale

Familial malignant mesothelioma: A population-based study in Central Italy (1980–2012)

Ascoli, Valeria ; Romeo, Elisa ; Carnovale Scalzo, Caterina ; Cozzi, Ilaria ; Ancona, Laura ; Cavariani, Fulvio ; Balestri, Anna ; Gasperini, Letizia ; Forastiere, Francesco

Malignant mesothelioma is a sporadic cancer linked to asbestos exposure. Its occurrence among blood relatives (familial mesothelioma) may point to genetic susceptibility or shared exposures. The burden of the familial disease is unknown. The aims of the study were to assess at population level the proportion of familial mesotheliomas among all mesotheliomas and to investigate the family history of cancer among relatives of mesothelioma cases. We actively searched familial clusters based on a [...]

A partir d'une revue systématique de la littérature, cette étude fait le point sur les traitements et la prise en charge des patients âgés de plus de 65 ans atteints d'un cancer localisé de l'œsophage

Management of Localized Esophageal Cancer in the Older Patient

Won, Elizabeth ; Ilson, David H.

Most patients with gastroesophageal cancers are older than 65 years of age. The management of older patients poses challenges because they have multiple comorbidities and physiological changes associated with aging. Furthermore, data are limited on tolerance of cancer therapy and the use of combined-modality treatments in this patient population to guide their treatment. In this article, we focus on the management of older patients with localized esophageal cancer, highlighting the role of [...]

A partir des données de la base d'assurance maladie de Taïwan portant sur 8 810 patientes atteintes d'un cancer de l'ovaire (âge médian : 49 ans), cette étude analyse les facteurs prédictifs du risque d'accidents vasculaires cérébraux ischémiques

Risk of ischemic stroke in patients with ovarian cancer: a nationwide population-based study

Kuan, Ai-Seon ; Teng, Chung-Jen ; Wu, Hua-Hsi ; Su, Vincent ; Chen, Yung-Tai ; Chien, Sheng-Hsuan ; Yeh, Chiu-Mei ; Hu, Li-Yu ; Chen, Tzeng-Ji ; Tzeng, Cheng-Hwai ; Liu, Chia-Jen

BACKGROUND:Cancer patients are at risk of thromboembolism. However, studies investigating the relationship between ovarian cancer and ischemic stroke are lacking. The objectives of this study were to assess the association between ovarian cancer and ischemic stroke, and to determine the predictive risk factors. METHODS:Ovarian cancer patients aged 20 years and older without antecedent cerebrovascular events and who were followed up for more than 1 year between 1 January 2003 and 31 December [...]

A partir des données des registres américains des cancers et de la base Medicare portant sur 69 718 patients âgés atteints d'un cancer colorectal diagnostiqué entre 1992 et 2009, cette étude de cohorte rétrospective analyse les effets des comorbidités, des toxicités médicamenteuses et des récentes chimiothérapies sur les causes de mortalité

Effects of newly developed chemotherapy regimens, comorbidities, chemotherapy-related toxicities on the changing patterns of the leading causes of death in elderly patients with colorectal cancer

Tong, Liyue ; Ahn, Chul ; Symanski, Elaine ; Lai, Dejian ; Du, Xianglin L.

Context : Abundant evidences have shown that newly developed chemotherapy regimens improved 5-year survival rate of CRC patients over the past two decades. However, their impact on risk of death from leading causes among elderly patients is still poorly understood. Objective : To assess the effect of newly developed chemotherapy regimens, comorbidities, and chemotherapy-related toxicities on cause-specific risk of death and their temporal patterns among elderly CRC patients. Design, Setting, [...]

A partir des données des registres américains des cancers portant sur 7 679 patientes atteintes d'un cancer inflammatoire du sein de stade III diagnostiqué entre 1990 et 2010, cette étude en population analyse l'évolution de la survie

Survival of women with inflammatory breast cancer: A large population based study

Dawood, S. ; Lei, X. ; Dent, R. ; Gupta, S. ; Sirohi, B. ; Cortés, J. ; Cristofanilli, M. ; Buchholz, T. ; Gonzalez-Angulo, A. M.

Background : Our group has previously reported that women with inflammatory breast cancer (IBC) continue to have worse outcome compared to those with non-inflammatory breast cancer. We undertook this population based study to see if there have been improvements in survival among women with stage III IBC, over time. Patient and Methods : We searched the Surveillance, Epidemiology and End Results Registry to identify female patients diagnosed with stage III IBC between 1990 and 2010. Patients [...]

A partir des données de l'Organisation Mondiale de la Santé, cette étude analyse l'évolution de la mortalité par cancer de l'endomètre dans 26 pays membres de l'Union européenne de 1970 à 2008

Trends in corpus uteri cancer mortality in member states of the European Union

Weiderpass, Elisabete ; Antoine, Jerome ; Bray, Freddie I. ; Oh, Jin-Kyoung ; Arbyn, Marc

The burden of corpus uteri cancer varies in the European Union (EU). We analysed trends in corpus uteri cancer mortality in 26 EU member states from 1970 onward. Population numbers and number of uterine cancer deaths were extracted from the World Health Organisation mortality database. Corpus uteri cancer mortality rates were corrected for certification problems using different reallocation rules for deaths registered as uterine cancer not otherwise specified, or using mixed disease codes. Join [...]

Menée en Corée auprès de 600 patients atteints d'un cancer de la tête et du cou de stade avancé, cette étude de cohorte analyse les morbidités non liées au cancer ainsi que la mortalité par autres causes que le cancer

Non-cancer health events as a leading cause of competing mortality in advanced head and neck cancer

Kwon, M. ; Roh, J.-L. ; Song, J. ; Lee, S.-W. ; Kim, S.-B. ; Choi, S.-H. ; Nam, S. Y. ; Kim, S. Y.

Background : The survival of patients with head and neck squamous cell carcinoma (HNSCC) can be affected by non-cancer health events (NCHE) as well as by index cancer progression and second primary cancer (SPC). This study aimed to investigate the risk factors for NCHE and non-cancer mortality (NCM) in patients with advanced-stage HNSCC. Patients and methods : This cohort study involved 600 consecutive patients with overall stage III to IV HNSCC who were treated between 2001 and 2010 at our [...]

Menée aux Etats-Unis auprès de 215 adolescents et jeunes adultes âgés de 15 à 39 ans et atteints de cancer, cette étude prospective analyse leur détresse psychologique et leurs besoins non satisfaits en soins de support psychosociaux durant la première année après le diagnostic de la maladie

Psychological distress and unsatisfied need for psychosocial support in adolescent and young adult cancer patients during the first year following diagnosis

Zebrack, Brad J. ; Corbett, Virginia ; Embry, Leanne ; Aguilar, Christine ; Meeske, Kathleen A. ; Hayes-Lattin, Brandon ; Block, Rebecca ; Zeman, David T. ; Cole, Steven

Purpose : Identifying at-risk adolescent and young adult (AYA) cancer patients and referring them to age-appropriate psychosocial support services may be instrumental in reducing psychological distress and promoting psychosocial adaptation. The purpose of this study is to identify trajectories of clinically significant levels of distress throughout the first year following diagnosis and to distinguish factors, including supportive care service use, that predict the extent to which AYAs report [...]

Menée en Indonésie auprès de 70 patientes atteintes d'un cancer du sein, cette étude évalue l'association entre des facteurs psychosociaux (consultation et croyance en des guérisseurs traditionnels, perceptions négatives de la maladie, etc) et leur adhésion aux traitements

Consulting a traditional healer and negative illness perceptions are associated with non-adherence to treatment in Indonesian women with breast cancer

Iskandarsyah, Aulia ; de Klerk, Cora ; Suardi, Dradjat R. ; Sadarjoen, Sawitri S. ; Passchier, Jan

Objective : The aim of the present study was to test the association between psychosocial factors and delay in uptake of treatment and treatment non-adherence in Indonesian women with breast cancer. Methods : Seventy consecutive patients with breast cancer who were treated at the Hasan Sadikin Hospital in Indonesia were recruited. They completed a demographic form, the non-adherence questionnaire, the Breast Cancer Knowledge Test, the Brief Illness Perception Questionnaire, the Multidimensional [...]

Menée en Corée par enquête auprès de 168 patientes atteintes d'un cancer du sein, cette étude transversale analyse les effets d'une alopécie induite par la chimiothérapie sur leur bien-être psychologique, leur image corporelle et leurs symptômes de dépression

Impact of chemotherapy-induced alopecia distress on body image, psychosocial well-being, and depression in breast cancer patients

Choi, Eun Kyung ; Kim, Im-Ryung ; Chang, Oliver ; Kang, Danbee ; Nam, Seok-Jin ; Lee, Jeong Eon ; Lee, Se Kyung ; Im, Young-Hyuck ; Park, Yeon Hee ; Yang, Jung-Hyun ; Cho, Juhee

Purpose : This study aims to evaluate the impact of chemotherapy-induced alopecia (CIA) distress on body image, psychosocial well-being, and depression among breast cancer patients. Methods : A cross-sectional survey was conducted at the breast cancer advocacy events held at 16 hospitals in Korea. Alopecia distress was assessed using the ‘Chemotherapy-Induced Alopecia Distress Scale’, body image and psychosocial well-being were measured by the European Organization for Research and Treatment of [...]

Menée aux Etats-Unis par enquête auprès de 174 participants, cette étude analyse l'association entre les difficultés financières rencontrées par les patients atteints de cancer et leur satisfaction relative à la qualité des soins

Self-Reported Financial Burden and Satisfaction With Care Among Patients With Cancer

Chino, Fumiko ; Peppercorn, Jeffrey ; Taylor, Donald H. ; Lu, Ying ; Samsa, Gregory ; Abernethy, Amy P. ; Zafar, S. Yousuf

Background : Health care-related costs and satisfaction are compelling targets for quality improvement in cancer care delivery; however, little is known about how financial burden affects patient satisfaction. Methods : This was an observational, cross-sectional, survey-based study assessing patient-reported financial burden (FB). Eligible patients were ≥21 years with solid tumor malignancy and were receiving chemotherapy or hormonal therapy for ≥1 month. The Patient Satisfaction Questionnaire [...]

Cet article passe en revue les travaux récents sur l'assurance qualité dans la prise en charge et les traitements d'un cancer colorectal et présente le programme européen "European Registration of Cancer Care"

Quality assurance in the treatment of colorectal cancer: the EURECCA initiative

Breugom, A. J. ; Boelens, P. G. ; van den Broek, C. B. M. ; Cervantes, A. ; Van Cutsem, E. ; Schmoll, H. J. ; Valentini, V. ; van de Velde, C. J. H.

Colorectal cancer is one of the most common cancers in Europe. Over the past few decades, important advances have been made in screening, staging and treatment of colorectal cancer. However, considerable variation between and within European countries remains, which implies that further improvements are possible. The most important remaining question now is: when are we, health care professionals, delivering the best available care to patients with colon or rectal cancer? Currently, quality [...]

Menée par enquête auprès d'oncologues pédiatriques canadiens, cette étude analyse leurs pratiques relatives à l'orientation de leurs jeunes patients atteints de cancer vers des unités de soins palliatifs

Referral practices of pediatric oncologists to specialized palliative care

Wentlandt, Kirsten ; Krzyzanowska, MonikaK ; Swami, Nadia ; Rodin, Gary ; Le, LisaW ; Sung, Lillian ; Zimmermann, Camilla

Purpose : The aims of this study are to describe the attitudes and referral practices of pediatric oncologists (POs) to specialized palliative care (SPC), and to compare them with those of adult oncologists (AOs). Methods : Canadian members of the American Society of Pediatric Hematology/Oncology (ASPHO), Canadian Association of Medical Oncologists (CAMO), Canadian Association of Radiation Oncologists (CARO), and the Canadian Society of Surgical Oncology (CSSO) participated in an anonymous [...]

Menée au Brésil par enquête téléphonique auprès de professionnels de santé en médecine générale (1 251 coordinateurs de réseau, 182 médecins, 347 infirmières, 273 intervenants sanitaires et sociaux), cette étude transversale analyse leurs connaissances et leurs pratiques vis-à-vis du cancer du col de l'utérus

Cervical Cancer-Related Knowledge, Attitudes, and Practices of Health Professionals Working in Brazil’s Network of Primary Care Units

Stormo, Analía Romina ; de Moura, Lenildo ; Saraiya, Mona

Introduction : Brazil’s national strategy for cervical cancer screening includes using the Papanicolaou (Pap) test every 3 years among women aged 25–64 years. Comprehensive primary care services are provided through a network of primary health units, but little is known about cervical cancer-related knowledge, attitudes, and practices among health professionals and coordinators working in these facilities. Methods : In 2011, we conducted a cross-sectional nationally representative phone survey [...]

Menée en Angleterre à partir des données de registres portant sur des patients atteints d'un cancer de la vessie diagnostiqué entre 1991 et 2010, cette étude évalue l'intérêt d'une procédure de contrôle-qualité des données pour améliorer les estimations de la survie

Control of data quality for population-based cancer survival analysis

Li, Ruoran ; Abela, Louise ; Moore, Jonathan ; Woods, Laura M. ; Nur, Ula ; Rachet, Bernard ; Allemani, Claudia ; Coleman, Michel P.

Background : Population-based cancer survival is an important measure of the overall effectiveness of cancer care in a population. Population-based cancer registries collect data that enable the estimation of cancer survival. To ensure accurate, consistent and comparable survival estimates, strict control of data quality is required before the survival analyses are carried out. In this paper, we present a basis for data quality control for cancer survival. Methods : We propose three distinct [...]