A partir d'une revue systématique de la littérature publiée de 2004 à 2012 (3 recommandations de pratique clinique, 12 essais randomisés), cette étude fait le point sur les différentes méthodes de prise en charge et de traitement des troubles du sommeil chez des patients atteints de cancer

Sleep disturbance in adults with cancer: a systematic review of evidence for best practices in assessment and management for clinical practice

Howell, D. ; Oliver, T. K. ; Keller-Olaman, S. ; Davidson, J. R. ; Garland, S. ; Samuels, C. ; Savard, J. ; Harris, C. ; Aubin, M. ; Olson, K. ; Sussman, J. ; MacFarlane, J. ; Taylor, C.

Sleep disturbance is prevalent in cancer with detrimental effects on health outcomes. Sleep problems are seldom identified or addressed in cancer practice. The purpose of this review was to identify the evidence base for the assessment and management of cancer-related sleep disturbance (insomnia and insomnia syndrome) for oncology practice. The search of the health literature included grey literature data sources and empirical databases from June 2004 to June 2012. The evidence was reviewed by [...]

Menée par enquête auprès de 542 patients atteints de cancer, cette étude longitudinale américaine analyse la prévalence et la persistence de symptômes liés à la maladie (durée de suivi : 12 mois)

The persistence of symptom burden: symptom experience and quality of life of cancer patients across one year

Deshields, TeresaL ; Potter, Patricia ; Olsen, Sarah ; Liu, Jingxia

Purpose : The purpose of this longitudinal study was to track the symptom experience in a sample of cancer patients, determine the persistence of cancer symptoms and symptom burden, and examine the relationship between symptoms and QOL over time. Methods : Five hundred forty-two patients provided longitudinal data, completing surveys over a 12-month period. Patients had breast, colorectal, gynecologic, lung, or prostate cancer with stage 1, 2, or 3 disease. Surveys included the Memorial Symptom [...]

Mené auprès de 205 patients atteints d'un cancer de la tête et du cou, cet essai analyse les effets à long terme d'une intervention psychosociale menée par un(e) infirmièr(e) sur la qualité de vie et les symptômes dépressifs des patients entre 12 et 14 mois après leur traitement

Long-term effect of a nurse-led psychosocial intervention on health-related quality of life in patients with head and neck cancer: a randomised controlled trial

van der Meulen, I. C. ; May, A. M. ; de Leeuw, J. R. J. ; Koole, R. ; Oosterom, M. ; Hordijk, G. J. ; Ros, W. J. G.

Background: Head and neck cancer (HNC) patients are prone to have a poor health-related quality of life after cancer treatment. This study investigated the effect of the nurse counselling and after intervention (NUCAI) on the health-related quality of life and depressive symptoms of HNC patients between 12 and 24 months after cancer treatment. Methods: Two hundred and five HNC patients were randomly allocated to NUCAI (N=103) or usual care (N=102). The 12-month nurse-led NUCAI is [...]

A partir d'une revue systématique de la littérature (22 articles), cette étude analyse les facteurs associés à l'adhésion aux traitements des patients âgés atteints de cancer

Factors influencing adherence to cancer treatment in older adults with cancer: a systematic review

Puts, M.T.E. ; Tu, H.A. ; Tourangeau, A. ; Howell, D. ; Fitch, M. ; Springall, E. ; Alibhai, S.M.H.

Background : Cancer is a disease that mostly affects older adults. Treatment adherence is crucial to obtain optimal outcomes such as cure or improvement in quality of life. Older adults have numerous comorbidites as well as cognitive and sensory impairments that may affect adherence. The aim of this systematic review was to examine factors that influence adherence to cancer treatment in older adults with cancer. Patients and Methods : Systematic review of the literature published between [...]

Menée par une approche de type écologique, cette étude épidémiologique analyse l'association entre des activités d'exploration et d'exploitation du pétrole et la mortalité par cancer en Equateur sur la période 1990-2010

Cancer mortality and quantitative oil production in the Amazon region of Ecuador, 1990–2010

Moolgavkar, SureshH ; Chang, EllenT ; Watson, Heather ; Lau, EdmundC

Purpose : Controversy persists over whether cancer risk is increased in communities surrounding oil fields, especially in the Oriente region of Ecuador. This ecologic study uses quantitative exposure data, updated mortality data, and improved statistical methods to study the impact of oil exploration and production activities on cancer mortality rates in the Oriente. Methods : Cancer mortality rates in the Oriente in 1990 through 2010 were compared between seven cantons with active oil [...]

A partir de données issues de diverses bases en Angleterre (registre des cancers, statistiques des séjours hospitaliers, office des statistiques nationales) portant sur 17 043 hommes atteints d'un cancer de la prostate, cette étude de cohorte rétrospective analyse l'impact des délais entre diagnostic et opération chirurgicale sur la survie des patients

Time from diagnosis to surgery and prostate cancer survival: a retrospective cohort study

Redaniel, Maria Theresa ; Martin, Richard ; Gillatt, David ; Wade, Julia ; Jeffreys, Mona

BACKGROUND:A diagnosis of prostate cancer leads to emotional distress and anxiety, prompting calls for rapid diagnostic pathways. Nevertheless, it remains unclear what impact time between diagnosis and surgery has upon prostate cancer survival. METHODS:Using national databases for England (cancer registries, Hospital Episode Statistics and Office of National Statistics), we identified 17,043 men with prostate cancer, aged 15 years and older, diagnosed in 1996--2009, and who had surgical [...]

A partir des données de l'étude internationale "Globocan" de 2008 et d'une revue systématique de la littérature, cette étude analyse l'incidence du cancer du sein chez des femmes âgées de moins de 44 ans en Amérique latine ainsi que la mortalité

Breast Cancer in Young Women in Latin America: An Unmet, Growing Burden

Villarreal-Garza, Cynthia ; Aguila, Christian ; Magallanes-Hoyos, Maria C. ; Mohar, Alejandro ; Bargalló, Enrique ; Meneses, Abelardo ; Cazap, Eduardo ; Gomez, Henry ; López-Carrillo, Lizbeth ; Chavarri-Guerra, Yanin ; Murillo, Raúl ; Barrios, Carlos

Background. Breast cancer (BC) is the leading cause of malignancy-related deaths among women aged ≤45 years. There are unexplored and uncertain issues for BC in this particular group in Latin America. The aim of this study is to evaluate BC incidence and mortality among young women and related clinicopathological and survivorship aspects in this region. Materials and Methods. Data were obtained from Globocan 2008 and the International Agency for Research on Cancer’s Cancer Incidence in Five [...]

Menée au Royaume-Uni auprès de 800 femmes âgées de 70 ans lors du diagnostic d'un cancer du sein opérable de stade 1-3a, cette étude de cohorte prospective analyse les facteurs associés au faible taux de traitements chirurgicaux observé dans cette population

Is lack of surgery for older breast cancer patients in the UK explained by patient choice or poor health ? A prospective cohort study

Lavelle, K. ; Sowerbutts, A. M. ; Bundred, N. ; Pilling, M. ; Degner, L. ; Stockton, C. ; Todd, C.

Background: Older women have lower breast cancer surgery rates than younger women. UK policy states that differences in cancer treatment by age can only be justified by patient choice or poor health. Methods: We investigate whether lack of surgery for older patients is explained by patient choice/poor health in a prospective cohort study of 800 women aged 70 years diagnosed with operable (stage 1–3a) breast cancer at 22 English breast cancer units in 2010–2013. Data collection: interviews and [...]

A partir des données du registre des cancers de l'Ontario portant sur 9 147 femmes atteintes d'un cancer de l'utérus diagnostiqué entre 2000 et 2009, cette étude analyse l'impact des délais entre le diagnostic et une hystérectomie sur la survie des patientes

Impact of Wait Times on Survival for Women With Uterine Cancer

Elit, Lorraine M. ; O'Leary, Erin M. ; Pond, Gregory R. ; Seow, Hsien-Yeang

Purpose : To determine whether wait time from histologic diagnosis of uterine cancer to time of definitive surgery by hysterectomy had an impact on all-cause survival.Patients and Methods : Women in Ontario with a confirmed histopathologic diagnosis of uterine cancer between April 1, 2000, and March 31, 2009, followed by surgery were identified in the Ontario Cancer Registry. Survival was calculated by using the Kaplan-Meier method. Factors were evaluated for their prognostic effect on survival [...]

Menée aux Etats-Unis auprès de 149 participants, cette étude analyse le recours aux services d'aide pyschologique parmi une population de patients atteints de cancer et recevant des soins palliatifs en hôpital de jour

Determinants of psychology service utilization in a palliative care outpatient population

Azuero, Casey ; Allen, Rebecca Sue ; Kvale, Elizabeth ; Azuero, Andres ; Parmelee, Patricia

Objective : Research has demonstrated that treating cancer patients' psychological and physical health leads to improved overall health. This may be especially true for palliative care patients facing serious illness. This study examines the proportion and determinants of psychology service utilization in an outpatient palliative care population. Methods : Data from an existing clinical database in an outpatient palliative clinic utilizing a collaborative care model to deliver psychology [...]

Mené aux Etats-Unis auprès de 1 070 patients atteints d'un cancer de la prostate, cet essai randomisé analyse les facteurs associés au sentiment de la perte de masculinité (dépression, anxiété, problèmes sexuels, effets indésirables de l'hormonothérapie anti-androgénique, dysfonctionnements urinaires)

Factors associated with feelings of loss of masculinity in men with prostate cancer in the RADAR trial

Sharpley, Christopher F. ; Bitsika, Vicki ; Denham, James W.

Objectives : To identify the factors underlying prostate cancer (PCa) patients' depression–anxiety, sexual problems, urinary dysfunction and androgen deprivation therapy (ADT)-linked breast changes and hot flushes, and test these as predictors of loss of masculinity (LoM) over 36 months following diagnosis. Methods : One thousand seventy patients from the TROG 03.04 (RADAR) trial the EORTC QLQ C-30 and PR 25 questionnaires, and the International Prostate Cancer Symptom Score of the American [...]

A partir des données de six registres allemands des cancers portant sur 2 671 survivantes à long terme d'un cancer du sein, cette étude en population analyse leur peur de la récidive de la maladie et son impact sur leur qualité de vie et leur dépression

Fear of recurrence in long-term breast cancer survivors—still an issue. Results on prevalence, determinants, and the association with quality of life and depression from the Cancer Survivorship—a multi-regional population-based study

Koch, Lena ; Bertram, Heike ; Eberle, Andrea ; Holleczek, Bernd ; Schmid-Höpfner, Sieglinde ; Waldmann, Annika ; Zeissig, Sylke R. ; Brenner, Hermann ; Arndt, Volker

Background : Fear of recurrence (FoR) is a widespread problem among breast cancer survivors. So far, little is known about prevalence, determinants, and consequences of FoR specifically in long-term breast cancer survivors, even though it was found to be one of the most important concerns in this group. Methods : Analyses are based on data of several population-based cohorts of long-term breast cancer survivors, recruited by six German cancer registries. Overall, 2671 women were included in the [...]

Cette étude britannique passe en revue les problématiques de l'organisation des soins de fin de vie pour les patients atteints de cancer et analyse leurs préférences relatives au lieu de leur décès

End-of-life care - what do cancer patients want?

Khan, Shaheen A. ; Gomes, Barbara ; Higginson, Irene J.

Patients with cancer frequently suffer from debilitating physical symptoms and psychological distress, particularly at the end of life. Interventions to help alleviate these problems are often complex and multifactorial. Palliative care services and therapeutic interventions have developed in a variable manner, often with limited evaluation of clinical effectiveness and affordability, resulting in a relatively weak evidence base. The health care provided to patients with advanced-stage cancer [...]

Cette étude présente les recommandations de la Société européenne d'oncologie pédiatrique visant à homogénéiser la prise en charge et les traitements des enfants atteints de cancer dans les pays européens

Towards reducing inequalities: European Standards of Care for Children with Cancer

Kowalczyk, Jerzy R. ; Samardakiewicz, Marzena ; Fitzgerald, Edel ; Essiaf, Samira ; Ladenstein, Ruth ; Vassal, Gilles ; Kienesberger, Anita ; Pritchard-Jones, Kathy

Despite the increase of cure rates in the treatment of children with cancer there is a significant discrepancy in the outcome within Europe. Data are showing us that there is a difference of 20% in outcomes for young people with cancer when comparing North and Western Europe with Central and Eastern Europe. One of the most important necessities, in order to be able to have comparable results and equitable outcomes about inequalities, is to have the Principle Treatment Centres, meeting a minimum [...]