A partir d'une revue systématique de la littérature (32 essais randomisés avec un total de 3 181 participants), cette méta-analyse évalue les effets d'interventions musicales sur la qualité de vie, psychologique et physique, de patients atteints de cancer

Music interventions for psychological and physical outcomes in cancer: a systematic review and meta-analysis

Zhang, Jun-Mei ; Wang, Pu ; Yao, Jia-xin ; Zhao, Lei ; Davis, Mellar ; Walsh, Declan ; Yue, Guang

Purpose A systematic review and meta-analysis to examine the effect of music interventions on psychological and physical outcome measures in cancer patients. Methods We searched six English-language databases and three major Chinese-language databases in March 2011. Nine databases were reviewed from 1966 or the start of the database to March 2011. All randomized controlled trials comparing music intervention with standard care, other interventions, or placebo for psychological and physical [...]

A partir d'une revue systématique de la littérature (22 études), cette étude analyse les divers outils permettant de décrire et de mesurer les symptômes des enfants atteints de cancer

A systematic review of symptom assessment scales in children with cancer

Dupuis, L ; Tomlinson, Deborah ; Ethier, Marie-Chantal ; Hesser, Tanya ; Sung, Lillian

BACKGROUND:The objective was to describe symptom assessment scales that have been used in children with cancer.METHODS:We conducted electronic searches of OVID Medline and EMBASE in order to identify all symptom assessment scales that have been used in pediatric cancer. Two reviewers abstracted information from each identified study. Data collected included study demographics and information related to the instrument and children enrolled. We also collected information about the purpose of [...]

Menée auprès de 1 885 survivants ayant reçu une greffe de cellules souches hématopoïétiques, cette étude américaine analyse l'incidence et les facteurs prédictifs de maladies cardiovasculaires

Cardiovascular risk factors in hematopoietic cell transplantation (HCT) survivors: role in development of subsequent cardiovascular disease

Armenian, Saro H. ; Sun, Can-Lan ; Vase, Tabitha ; Ness, Kirsten K. ; Blum, Emily ; Francisco, Liton ; Venkataraman, Kalyanasundaram ; Samoa, Raynald ; Wong, F. Lennie ; Forman, Stephen J. ; Bhatia, Smita

HCT recipients may be at an increased risk of developing hypertension, diabetes and dyslipidemia (referred to as cardiovascular risk factors ([CVRFs]); and these can potentially increase the risk of cardiovascular disease (CVD). We examined the incidence and predictors of CVRFs and subsequent CVD in 1885 consecutive 1+year survivors of HCT performed at City of Hope between 1995 and 2004. Ten-year cumulative incidence (CI) of hypertension, diabetes, dyslipidemia, and multiple (≥2) CVRFs was [...]

Menée en Australie par enquête téléphonique et enquête en ligne, cette étude transversale analyse la pratique d'activité physique de 229 patients atteints de myélome multiple ainsi que leurs freins à cette activité

Physical activity participation and barriers for people with multiple myeloma

Craike, Melinda ; Hose, Kaye ; Livingston, Patricia

Purpose This study aims to examine, for people treated for multiple myeloma, (1) differences between prediagnosis and postdiagnosis levels of physical activity, (2) perceived barriers and likelihood of attending a physical activity program, and (3) factors that influence whether or not respondents are meeting physical activity guidelines. Methods This was a quantitative cross-sectional study; data were gathered from a larger Australian population-wide survey. Respondents completed the survey in [...]

A partir des données de la cohorte "Women’s Health Initiative" incluant 1 339 participantes, cette étude prospective évalue l'association entre la pratique d'une activité physique de loisir, l'indice de masse corporelle et la survie des patientes atteintes d'un cancer colorectal

Recreational physical activity, body mass index, and survival in women with colorectal cancer

Kuiper, Josephina ; Phipps, Amanda ; Neuhouser, Marian ; Chlebowski, Rowan ; Thomson, Cynthia ; Irwin, Melinda ; Lane, Dorothy ; Wactawski-Wende, Jean ; Hou, Lifang ; Jackson, Rebecca ; Kampman, Ellen ; Newcomb, Polly

Background and purpose Previous studies have shown that physical inactivity and obesity are risk factors for the development of colorectal cancer. However, controversy exists regarding the influence of these factors on survival in colorectal cancer patients. We evaluated the impact of recreational physical activity and body mass index (BMI) before and after colorectal cancer diagnosis on disease-specific mortality and all-cause mortality. Patients and methods This prospective cohort study [...]

A partir d'une revue de la littérature des essais randomisés (18 essais), cette étude analyse l'efficacité de séances de yoga pour améliorer la qualité de vie de patientes atteintes d'un cancer du sein

Randomised controlled trials of yoga interventions for women with breast cancer: a systematic literature review

Harder, H. ; Parlour, L. ; Jenkins, V.

Purpose Yoga is increasingly used as a complementary therapy to manage disease and treatment-related side effects in patients with cancer and has resulted in an increase in the number of studies exploring the effectiveness of yoga interventions. This systematic review examines whether yoga interventions provide any measurable benefit, both physically and psychologically, for women with breast cancer. The results will inform future research in this field and advance the development of yoga [...]

Cette méta-analyse de 17 études fait le point sur l'efficacité de la pratique d'une activité physique sur la qualité de vie, psychologique et physique, de patientes atteintes d'un cancer du sein recevant une thérapie adjuvante, et évalue le volume optimal d'exercices

Psychological effect of exercise in women with breast cancer receiving adjuvant therapy: what is the optimal dose needed?

Carayol, M. ; Bernard, P. ; Boiché, J. ; Riou, F. ; Mercier, B. ; Cousson-Gélie, F. ; Romain, A. J. ; Delpierre, C. ; Ninot, G.

Background Several meta-analyses have examined the role of exercise interventions in improving psychological outcomes in cancer survivors but most did not focus on adjuvant therapy period and did not investigate the optimal dose of exercise needed. The present meta-analysis examines the impact of exercise interventions delivered at this particular period on fatigue, anxiety, depression, and quality of life (QoL) as well as dose–response relationships between volume of prescribed exercise and [...]

Menée au Brésil auprès de 28 patients atteints d'un cancer de la tête et du cou et recevant une radiothérapie avec ou sans chimiothérapie, cette étude évalue leurs besoins en soins parodontaux

Periodontal care in patients undergoing radiotherapy for head and neck cancer

Bueno, Audrey ; Ferreira, Raquel ; Barbosa, Flávia ; Jham, Bruno ; Magalhães, Cláudia ; Moreira, Allyson

Purpose The aim of this study was to evaluate periodontal changes after periodontal treatment and control in patients with malignant tumors of the upper aerodigestive tract who were submitted to radiotherapy with or without chemotherapy. Methods We included all patients attending the Oncology Clinic of the Federal University of Minas Gerais, School of Dentistry. Clinical periodontal parameters obtained by a single calibrated examiner were evaluated at baseline, 10 days after radiotherapy, and [...]

Menée auprès de 532 survivants adultes d'un cancer pédiatrique, cette étude de cohorte rétrospective évalue l'association entre des polymorphismes à simple nucléotide de gènes impliqués dans la résistance à l'insuline, la pression sanguine et l'adiposité, des facteurs liés aux traitements reçus, et le syndrome métabolique

Treatment factors rather than genetic variation determine metabolic syndrome in childhood cancer survivors

van Waas, Marjolein ; Neggers, Sebastian J. C. M. M. ; Uitterlinden, André G. ; Blijdorp, Karin ; van der Geest, Ivana M. M. ; Pieters, Rob ; van den Heuvel-Eibrink, Marry M.

Genetic variation that regulates insulin resistance, blood pressure and adiposity in the normal population might determine differential vulnerability for metabolic syndrome after treatment for childhood cancer. To evaluate the contribution of candidate single nucleotide polymorphisms (SNPs) relevant for metabolic syndrome in our single centre cohort of adult long-term childhood cancer survivors. In this retrospective study 532 survivors were analysed. Median age at diagnosis was 5.7years (range [...]

Menée en Italie, cette étude observationnelle analyse l'évolution de la mortalité par cancer parmi une population âgée de 65 à 84 ans, sur la période 1970-2008

Time trends of cancer mortality among elderly in Italy, 1970--2008: an observational study

Bidoli, Ettore ; Fratino, Lucia ; Bruzzone, Silvia ; Pappagallo, Marilena ; De Paoli, Paolo ; Tirelli, Umberto ; Serraino, Diego

BACKGROUND:The aging of the Italian population will unavoidably lead to a growing number of persons diagnosed and living with cancer. A comprehensive description of the burden of cancer mortality among Italian elderly (65-84 years of age) in the last four decades has not been carried out yet. Cancer mortality rates were used to describe time trends between 1970-2008.METHODS:Mortality counts, provided by the Italian National Institute of Statistics, were grouped according to data availability: [...]

Menée auprès de 179 survivants d'un cancer hématologique pédiatrique, cette étude analyse l'évolution de leur indice de masse corporelle après une greffe allogénique de cellules souches hématopoïétiques

Longitudinal Changes in Body Mass and Composition in Survivors of Childhood Hematologic Malignancies After Allogeneic Hematopoietic Stem-Cell Transplantation

Inaba, Hiroto ; Yang, Jie ; Kaste, Sue C. ; Hartford, Christine M. ; Motosue, Megan S. ; Chemaitilly, Wassim ; Triplett, Brandon M. ; Shook, David R. ; Pui, Ching-Hon ; Leung, Wing

Purpose To measure longitudinal changes in body mass and composition in survivors of childhood hematologic malignancies after allogeneic hematopoietic stem-cell transplantation (HSCT).Patients and Methods Body mass index (BMI) was analyzed in 179 survivors by category (underweight, healthy-weight, overweight, and obese) and by z score. Fat and lean body mass measured by dual-energy x-ray absorptiometry was analyzed as z scores.Results Over a median 6.6 years of follow-up, BMI z scores [...]

Menée auprès de 237 patients atteints d'un lymphome folliculaire de stade limité, cette étude analyse le risque, après une durée médiane de suivi de 7,4 ans, d'une évolution de la maladie vers une forme agressive liée à une radiothérapie initiale

Incidence of transformation to aggressive lymphoma in limited-stage follicular lymphoma treated with radiotherapy

Bains, P. ; Al Tourah, A. ; Campbell, B.A. ; Pickles, T. ; Gascoyne, R. D. ; Connors, J.M. ; Savage, K. J.

Background The established treatment of limited-stage follicular lymphoma is radiotherapy (RT). There is an inherent risk of transformation of follicular lymphoma to aggressive lymphoma; however, the frequency and impact on the outcome are unknown in limited-stage patients.Materials and methods We identified 237 patients with limited-stage follicular lymphoma treated with curative intent RT. Cases were reviewed to determine the frequency of transformation and subsequent survival.Results With a [...]

A partir des données du registre néerlandais du cancer, cette étude en population analyse les caractéristiques tumorales du mélanome d'orgine primitive inconnue ainsi que la survie des patients, sur la période 2003-2009

Melanoma of unknown primary origin: A population-based study in the Netherlands

de Waal, Anne C. ; Aben, Katja K. H. ; van Rossum, Michelle M. ; Kiemeney, Lambertus A. L. M.

Few population-based studies have been published on melanoma of unknown primary origin (MUP). This study’s aim is to describe characteristics and survival of MUP patients in the Netherlands, based on nationwide data from the Netherlands Cancer Registry (NCR). Patient and tumour characteristics of MUP patients were retrieved from the NCR. Subgroups were made according to metastatic site: nodal or distant. Survival rates were calculated using the Kaplan–Meier method. To obtain a better insight in [...]

A partir des données de 36 624 patientes opérées d'un cancer de l'ovaire, cette étude montre que l'association entre le volume annuel d'opérations chirurgicales et la mortalité s'explique davantage par la capacité d'un hôpital à gérer les complications opératoires plutôt que par le taux de complications survenues

Failure to Rescue As a Source of Variation in Hospital Mortality for Ovarian Cancer

Wright, Jason D. ; Herzog, Thomas J. ; Siddiq, Zainab ; Arend, Rebecca ; Neugut, Alfred I. ; Burke, William M. ; Lewin, Sharyn N. ; Ananth, Cande V. ; Hershman, Dawn L.

Purpose Although the association between high surgical volume and improved outcomes from procedures is well described, the mechanisms that underlie this association are uncertain. There is growing recognition that high-volume hospitals may not necessarily have lower complication rates but rather may be better at rescuing patients with complications. We examined the role of complications, failure to rescue from complications, and mortality based on hospital volume for ovarian cancer.Patients And [...]

Menée aux Etats-Unis auprès de 4 157 patients atteints d'un cancer de la prostate et ayant subi une prostatectomie radicale, cette étude de cohorte évalue les disparités ethniques dans l'aggressivité, le grade et le volume de leurs tumeurs

African-American men with low-grade prostate cancer have higher tumor burdens: Results from the Duke Prostate Center

Tsivian, M. ; Banez, L. L. ; Keto, C. J. ; Abern, M. R. ; Qi, P. ; Gerber, L. ; Moul, J. W. ; Polascik, T. J.

Background: To investigate racial differences in tumor burden (cancer volume, cancer percentage and cancer to PSA ratios) in a large cohort of men undergoing radical prostatectomy (RP). Methods: Demographic, clinical and pathological data of patients undergoing RP between 1993–2010 were reviewed and compared between African-American (AA) and non African-American (nAA) men. Further assessments of pathological tumor burden (estimated tumor volume, percent of cancer involvement, and estimated [...]

A partir d'une revue systématique de la littérature (8 études), cette étude analyse les disparités ethniques dans le suivi médical par coloscopie régulière de survivants d'un cancer colorectal

Ethnic disparities in colonoscopy use among colorectal cancer survivors: a systematic review

Salz, Talya ; Woo, Heidi ; Starr, Tatiana ; Jandorf, Lina ; DuHamel, Katherine

Purpose After curative treatment for colorectal cancer (CRC), routine colonoscopies are recommended. We aimed to identify all studies of ethnic disparities in CRC surveillance and examine any association between race/ethnicity and colonoscopy use. Methods We conducted a systematic literature review to address the association between race/ethnicity and colonoscopy use among CRC survivors. We searched Medline for relevant articles. Two authors reviewed titles, abstracts, and articles based on [...]

Menée aux Etats-Unis auprès de 471 survivantes d'un cancer du sein, cette étude de cohorte analyse la prévalence de la sarcopénie et son impact sur la mortalité

Prevalence and prognostic effect of sarcopenia in breast cancer survivors: the HEAL Study

Villaseñor, Adriana ; Ballard-Barbash, Rachel ; Baumgartner, Kathy ; Baumgartner, Richard ; Bernstein, Leslie ; McTiernan, Anne ; Neuhouser, Marian

Purpose This study aimed to determine the prevalence of sarcopenia and examine whether sarcopenia was associated with overall and breast-cancer-specific mortality in a cohort of women diagnosed with breast cancer (stages I–IIIA). Methods A total of 471 breast cancer patients from western Washington State and New Mexico who participated in the prospective Health, Eating, Activity, and Lifestyle Study were included in this study. Appendicular lean mass was measured using dual X-ray absorptiometry [...]

Menée au Kenya auprès de 498 femmes infectées par le VIH et recevant un traitement antirétroviral, cette étude transversale analyse la prévalence et les déterminants d'une infection par le papillomavirus humain et de néoplasies cervicales intraépithéliales

Prevalence and determinants of human papillomavirus infection and cervical lesions in HIV-positive women in Kenya

De Vuyst, H. ; Mugo, N. R. ; Chung, M. H. ; McKenzie, K. P. ; Nyongesa-Malava, E. ; Tenet, V. ; Njoroge, J. W. ; Sakr, S. R. ; Meijer, Cjl M. ; Snijders, P. J. F. ; Rana, F. S. ; Franceschi, S.

Background: We assessed the association of human papillomavirus (HPV) infection and cervical intraepithelial neoplasia (CIN) with various characteristics, CD4 count and use of combination antiretroviral therapy (cART) among HIV-positive women. Methods: Cross-sectional study of 498 HIV-positive women who underwent HPV PCR-based testing, cytology, and systematic cervical biopsy. Results: In all, 68.7% of women were HPV-positive, 52.6% had high-risk (hr) HPV, and 40.2% multiple type infections. [...]

Menée aux Etats-Unis auprès de 75 patients pédiatriques atteints de cancer et leurs parents, cette étude longitudinale analyse l'auto-efficacité (croyance d'un individu en sa capacité d’atteindre ou non un objectif) des parents dans leur rôle d'aidants dans le cadre des procédures thérapeutiques ainsi que leurs symptômes de stress associés

Longitudinal study of parent caregiving self-efficacy and parent stress reactions with pediatric cancer treatment procedures

Harper, Felicity W. K. ; Peterson, Amy M. ; Uphold, Heatherlun ; Albrecht, Terrance L. ; Taub, Jeffrey W. ; Orom, Heather ; Phipps, Sean ; Penner, Louis A.

Background Pain/distress during pediatric cancer treatments has substantial psychosocial consequences for children and families. We examined relationships between parents' caregiving self-efficacy, parents' affect in response to their children's cancer-related treatment procedures, and parents' symptoms of post-traumatic stress at follow-up. Methods Participants were 75 pediatric cancer patients and parents. On the day of each of three procedures (i.e., port-start, lumbar puncture, or bone [...]

Menée en Norvège auprès de 526 participantes, cette étude analyse les effets psychologiques d'une invitation à effectuer des examens complémentaires à la suite d'une mammographie de dépistage présentant des anomalies

Recall mammography and psychological distress

Schou Bredal, Inger ; Kåresen, Rolf ; Skaane, Per ; Engelstad, Kari Sletten ; Ekeberg, Øivind

The aims of this study were (a) to identify psychological distress before and after being diagnosed with or without cancer in women recalled for further investigation because previous screening mammography indicated possible malignancy and (b) to document the willingness to attend and recommend mammography. Study participants included 526 recalled women (82% response) who completed a questionnaire before the recall mammogram and 4weeks after receiving the result. Psychological distress was [...]

Menée au Royaume-Uni, cette étude analyse le rapport coût-efficacité de deux stratégies d'utilisation du test de détection du papillomavirus humain pour gérer des résultats équivoques lors d'un dépistage du cancer du col de l'utérus

Cost and logistics of alternative roll-out options for implementing human papillomavirus testing as a triage in cervical screening: results of the sentinel sites study

Legood, R. ; Sadique, Z. ; Patnick, J. ; Kitchener, H. ; Kelly, R. ; Moss, S.

Background: Previous studies have indicated that human papillomavirus (HPV) testing as a triage for managing equivocal cytology is cost-effective. The aim of this study was to assess the costs of alternative roll-out options. Methods: Detailed cost estimates were collected from six laboratories where HPV triage had been implemented. Costs were assessed for the two different service delivery models that were implemented; a ‘hub and spoke model’ of central HPV testing in a microbiology laboratory [...]

Cette étude française analyse l'efficacité et l'exactitude d'un indicateur, l'estimateur de Pohar-Perme, pour mesurer la survie nette à partir de données des registres des cancers

Cancer net survival on registry data: Use of the new unbiased Pohar-Perme estimator and magnitude of the bias with the classical methods

Roche, Laurent ; Danieli, Coraline ; Belot, Aurélien ; Grosclaude, Pascale ; Bouvier, Anne-Marie ; Velten, Michel ; Iwaz, Jean ; Remontet, Laurent ; Bossard, Nadine

Net survival, the survival which might occur if cancer was the only cause of death, is a major epidemiological indicator required for international or temporal comparisons. Recent findings have shown that all classical methods used for routine estimation of net survival from cancer-registry data, sometimes called “relative-survival methods,” provide biased estimates. Meanwhile, an unbiased estimator, the Pohar-Perme estimator (PPE), was recently proposed. Using real data, we investigated the [...]

Cet article analyse la pertinence d'adopter ou d'adapter en Asie les connaissances produites par la recherche occidentale dans le domaine du cancer du sein

Breast cancer research in Asia: Adopt or adapt Western knowledge?

Bhoo-Pathy, Nirmala ; Yip, Cheng-Har ; Hartman, Mikael ; Uiterwaal, Cuno S. P. M. ; Devi, Beena C. R. ; Peeters, Petra H. M. ; Taib, Nur Aishah ; van Gils, Carla H. ; Verkooijen, Helena M.

The incidence and mortality of breast cancer continues to rise rapidly in Asian countries. However, most of our current knowledge on breast cancer has been generated in Western populations. As the socio-economic profile, life style and culture of Asian and Western women are substantially different, and genetic backgrounds vary to some extent, we need to answer the question on whether to ‘adopt’ or ‘adapt’ Western knowledge before applying it in the Asian setting. It is generally accepted that [...]