Menée en Australie sur la période 2011-2016 auprès de 1 184 témoins et 681 patients atteints d'un lymphome folliculaire, cette étude analyse l'association entre une exposition professionnelle aux champs magnétiques d'extrêmement basse fréquence et le risque de développer la maladie

Occupational exposure to extremely low-frequency magnetic fields and follicular lymphoma risk: a family case–control study

Michael K Odutola ; Marina T van Leeuwen ; Fiona J Bruinsma ; Geza Benke ; Michelle C Turner ; Judith Trotman ; Jennifer Turner ; John F Seymour ; H Miles Prince ; Samuel T Milliken ; Campbell Tiley ; Mark Hertzberg ; Fernando Roncolato ; Stephen Opat ; Robert Lindeman ; Emma Verner ; Craig R Underhill ; Elisabeth Cardis ; Graham Giles ; Claire M Vajdic

Objectives: We aimed to examine the relationship between occupational exposure to extremely low-frequency magnetic fields (ELF-MFs) and follicular lymphoma (FL) risk. Methods: We conducted a family case–control study between 2011 and 2016 in Australia and included 681 cases. Controls were either a family member of cases (related (n=294), unrelated (n=179)) or were unrelated recruited for a similarly designed Australian multiple myeloma study (n=711). We obtained detailed job histories using [...]

Menée en Espagne sur la période 2010-2013 auprès de 2 470 témoins et 301 patients atteints d'une leucémie lymphoïde chronique, cette étude analyse l'association entre une exposition aux trihalométhanes et aux nitrates dans l'eau de boisson ou dans une piscine au cours de la vie et le risque de développer la maladie

Lifetime exposure to brominated trihalomethanes in drinking water and swimming pool attendance are associated with chronic lymphocytic leukemia: a Multicase-Control Study in Spain (MCC-Spain)

Donat-Vargas, Carolina ; Kogevinas, Manolis ; Benavente, Yolanda ; Costas, Laura ; Campo, Elias ; Castaño-Vinyals, Gemma ; Fernández-Tardón, Guillermo ; Llorca, Javier ; Gómez-Acebo, Inés ; Aragonés, Nuria ; Pollan, Marina ; Casabonne, Delphine ; Villanueva, Cristina M.

Background: Chronic lymphocytic leukemia (CLL) etiology is poorly understood, and carcinogenic chemicals in drinking and recreational water are candidates. Objective: To evaluate the association between drinking-water exposure to trihalomethanes (THMs) and nitrate as well as lifetime swimming pool attendance and CLL. Methods: During 2010–2013, hospital-based CLL cases and population-based controls were recruited in Spain, providing information on residential histories, type of water consumed [...]

A partir d'une revue systématique de la littérature (14 études), cette méta-analyse évalue l'association entre une colonisation orale par Candida spp. et le risque de carcinome épidermoïde buccal

Candida species as potential risk factors for oral squamous cell carcinoma: Systematic review and meta-analysis

Tasso, Camilla Olga ; Ferrisse, Túlio Morandin ; de Oliveira, Analú Barros ; Ribas, Beatriz Ribeiro ; Jorge, Janaina Habib

Oral squamous cell carcinoma (OSCC) is considered a multifactorial disease and has been associated with microbial infections, although the association with Candida spp. is still controversial. This systematic review focused on clinical trials which evaluated the relation between oral Candida spp colonization and OSCC. PubMed; Scopus; Embase; Web of Science and Scientific Direct were assessed. Independent reviewers conducted the diagram steps. For data extraction the PRISMA protocol was [...]

Menée à partir de données internationales 1986-2020 portant sur 1 183 999 personnes, cette étude analyse l'association entre une utilisation d'antagonistes des récepteurs de l'histamine-2, en particulier la ranitidine, et le risque de cancer (16 localisations)

Ranitidine Use and Incident Cancer in a Multinational Cohort

You, Seng Chan ; Seo, Seung In ; Falconer, Thomas ; Yanover, Chen ; Duarte-Salles, Talita ; Seager, Sarah ; Posada, Jose D. ; Shah, Nigam H. ; Nguyen, Phung-Anh ; Kim, Yeesuk ; Hsu, Jason C. ; Van Zandt, Mui ; Hsu, Min-Huei ; Lee, Hang Lak ; Ko, Heejoo ; Shin, Woon Geon ; Pratt, Nicole ; Park, Rae Woong ; Reich, Christin G. ; Suchard, Marc A. ; Hripcsak, George ; Park, Chan Hyuk ; Prieto-Alhambra, Daniel

Ranitidine, the most widely used histamine-2 receptor antagonist (H2RA), was withdrawn because of N-nitrosodimethylamine impurity in 2020. Given the worldwide exposure to this drug, the potential risk of cancer development associated with the intake of known carcinogens is an important epidemiological concern.To examine the comparative risk of cancer associated with the use of ranitidine vs other H2RAs.This new-user active comparator international network cohort study was conducted using 3 [...]

Menée à l'aide de données portant sur 17 903 femmes ayant survécu à un cancer pédiatrique, cette étude analyse l'association entre la dose de chimiothérapie à base d'anthracycline reçue et le risque de cancer du sein (782 cas)

Subsequent female breast cancer risk associated with anthracycline chemotherapy for childhood cancer

Wang, Yuehan ; Ronckers, Cecile M. ; van Leeuwen, Flora E. ; Moskowitz, Chaya S. ; Leisenring, Wendy ; Armstrong, Gregory T. ; de Vathaire, Florent ; Hudson, Melissa M. ; Kuehni, Claudia E. ; Arnold, Michael A. ; Demoor-Goldschmidt, Charlotte ; Green, Daniel M. ; Henderson, Tara O. ; Howell, Rebecca M. ; Ehrhardt, Matthew J. ; Neglia, Joseph P. ; Oeffinger, Kevin C. ; van der Pal, Helena J. H. ; Robison, Leslie L. ; Schaapveld, Michael ; Turcotte, Lucie M. ; Waespe, Nicolas ; Kremer, Leontien C. M. ; Teepen, Jop C. ; Haddy, Nadia ; Diallo, Ibrahima ; Baker, K. Scott ; de González, Amy Berrington ; Conces, Miriam R. ; Constine, Louis S. ; Hawkins, Mike ; Loonen, Jacqueline J. ; Louwerens, Marloes ; Janssens, Geert O. ; Mellemkjaer, Lene ; Reulen, Raoul ; Winther, Jeanette F. ; The International Consortium for Pooled Studies on Subsequent Malignancies after, Childhood ; Adolescent, Cancer

Anthracycline-based chemotherapy is associated with increased subsequent breast cancer (SBC) risk in female childhood cancer survivors, but the current evidence is insufficient to support early breast cancer screening recommendations for survivors treated with anthracyclines. In this study, we pooled individual patient data of 17,903 survivors from six well-established studies, of whom 782 (4.4%) developed a SBC, and analyzed dose-dependent effects of individual anthracycline agents on [...]

Menée à l'aide de données d'études chinoises portant sur 954 témoins et 959 patients atteints d'un cancer du poumon et n'ayant jamais fumé, cette étude analyse l'association entre la longueur des télomères leucocytaires et le risque de développer la maladie

Associations between longer leukocyte telomere length and increased lung cancer risk among never smokers in urban China

Wong, Jason YY. ; Shu, Xiao-Ou ; Hu, Wei ; Blechter, Batel ; Shi, Jianxin ; Wang, Kevin ; Cawthon, Richard ; Cai, Qiuyin ; Yang, Gong ; Rahman, Mohammad L. ; Ji, Bu-Tian ; Gao, Yutang ; Zheng, Wei ; Rothman, Nathaniel ; Lan, Qing

Background: The complex relationship between measured leukocyte telomere length (LTL), genetically-predicted LTL (gTL), and carcinogenesis is exemplified by lung cancer. We previously reported associations between longer pre-diagnostic LTL, gTL, and increased lung cancer risk among European and East Asian populations. However, we had limited statistical power to examine the associations among never smokers by gender and histology. Methods: To investigate further, we conducted nested [...]