Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
Pour retrouver les publications signalées par Nota Bene Cancer (archives indexées à partir du n°127 du 1" mars 2012) :
Sommaire du n° 558 du 20 mars 2023
Qualité de vie, soins de support (4)
A partir d'une revue systématique de la littérature publiée entre 1946 et 2022 (6 essais randomisés incluant un total de 627 patients), cette méta-analyse évalue l'efficacité des agents topiques non stéroïdiens pour prévenir une radiodermite chez des patients atteints d'un cancer
Topical non-steroidal agents for the prevention of radiation dermatitis: a systematic review and meta-analysis
A partir d'une revue systématique de la littérature publiée entre 1946 et 2022 (6 essais randomisés incluant un total de 627 patients), cette méta-analyse évalue l'efficacité des agents topiques non stéroïdiens pour prévenir une radiodermite chez des patients atteints d'un cancer
Topical non-steroidal agents for the prevention of radiation dermatitis: a systematic review and meta-analysis
Fatima, Sakeena ; Hirakawa, Satoshi ; Marta, Gustavo Nader ; Caini, Saverio ; Beveridge, Mara ; Bonomo, Pierluigi ; Chow, Edward ; van den Hurk, Corina ; Ryan Wolf, Julie ; Lam, Henry ; Behroozian, Tara
Purpose: Radiation dermatitis (RD) is a common side effect of radiation therapy, affecting a majority of breast and head and neck cancer patients with a negative impact on quality of life. Currently, no consensus exists regarding the prevention of RD. Methods: PubMed, Embase and Cochrane databases (1946 to December 2022) were searched using PRISMA guidelines to identify randomized controlled trials (RCTs) that investigated the use of topical non-steroidal agents in the prevention of RD in [...]
Menée en Australie par enquête auprès de 2 198 patientes ayant survécu à un cancer du sein (âge médian : 60,1 ans ; 177 réponses), cette étude analyse la présence de comorbidités et leur prise en charge
Comorbidities and their management in women with breast cancer—an Australian survey of breast cancer survivors
Menée en Australie par enquête auprès de 2 198 patientes ayant survécu à un cancer du sein (âge médian : 60,1 ans ; 177 réponses), cette étude analyse la présence de comorbidités et leur prise en charge
Comorbidities and their management in women with breast cancer—an Australian survey of breast cancer survivors
Koczwara, Bogda ; Meng, Rosie ; Battersby, Malcolm ; Mangoni, Arduino A. ; Spence, Danielle ; Lawn, Sharon
Purpose: Breast cancer survivors experience significant burden from comorbid chronic conditions, but little is known about how well these conditions are managed. We conducted a national survey of Australian breast cancer survivors to examine the burden of chronic conditions, their impact and care alignment with the principles of chronic condition management. Methods: A study-specific survey incorporated questions about chronic conditions using the Charlson Comorbidity Index (CCI), functional [...]
Menée à partir de données portant sur 256 patients atteints d'un gliome diffus, cette étude identifie des modèles d'association entre divers symptômes (dépression, troubles cognitifs, fatigue, fonctionnement social, etc.) et la qualité de vie
Symptom networks in glioma patients: understanding the multidimensionality of symptoms and quality of life
Menée à partir de données portant sur 256 patients atteints d'un gliome diffus, cette étude identifie des modèles d'association entre divers symptômes (dépression, troubles cognitifs, fatigue, fonctionnement social, etc.) et la qualité de vie
Symptom networks in glioma patients: understanding the multidimensionality of symptoms and quality of life
Röttgering, J. G. ; Varkevisser, T. M. C. K. ; Gorter, M. ; Belgers, V. ; De Witt Hamer, P. C. ; Reijneveld, J. C. ; Klein, M. ; Blanken, T. F. ; Douw, L.
Purpose: To comprehend the complex relationship between symptoms and health-related quality of life (HRQoL) in patients with diffuse glioma, we applied symptom network analysis to identify patterns of associations between depression, cognition, brain tumor-related symptoms, and HRQoL. Additionally, we aimed to compare global strength between symptom networks to understand if symptoms are more tightly connected in different subgroups of patients. Methods: We included 256 patients and stratified [...]
Mené sur 202 patientes ayant survécu à un cancer du col de l'utérus ou à une néoplasie intraépithéliale cervicale, cet essai randomisé évalue l'efficacité, du point de vue de l'abstinence tabagique à 18 mois, d'une intervention de sevrage tabagique comportant des conseils téléphoniques et des substituts nicotiniques
Efficacy of a Smoking Cessation Intervention for Survivors of Cervical Intraepithelial Neoplasia or Cervical Cancer: A Randomized Controlled Trial
Mené sur 202 patientes ayant survécu à un cancer du col de l'utérus ou à une néoplasie intraépithéliale cervicale, cet essai randomisé évalue l'efficacité, du point de vue de l'abstinence tabagique à 18 mois, d'une intervention de sevrage tabagique comportant des conseils téléphoniques et des substituts nicotiniques
Efficacy of a Smoking Cessation Intervention for Survivors of Cervical Intraepithelial Neoplasia or Cervical Cancer: A Randomized Controlled Trial
Jennifer I. Vidrine ; Steven K. Sutton ; David W. Wetter ; Ya-Chen Tina Shih ; Lois M. Ramondetta ; Linda S. Elting ; Joan L. Walker ; Katie M. Smith ; Summer G. Frank-Pearce ; Yisheng Li ; Sarah R. Jones ; Darla E. Kendzor ; Vani N. Simmons ; Damon J. Vidrine
PURPOSE: Women who smoke and have a history of cervical intraepithelial neoplasia (CIN) or cervical cancer represent a vulnerable subgroup at elevated risk for recurrence, poorer cancer treatment outcomes, and decreased quality of life. The purpose of this study was to evaluate the long-term efficacy of Motivation And Problem Solving (MAPS), a novel treatment well-suited to meeting the smoking cessation needs of this population. METHODS: Women who were with a history of CIN or cervical cancer, [...]
Observation (5)
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Quality of Life of early-stage breast-cancer patients diagnosed with COVID-19 in the first three waves of the epidemic treated in the Spanish regio...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Quality of Life of early-stage breast-cancer patients diagnosed with COVID-19 in the first three waves of the epidemic treated in the Spanish region of Navarre
Arraras, Juan Ignacio ; Illarramendi, Jose Juan ; Manterola, Ana ; Cruz, Susana de la ; Zarandona, Uxue ; Ibáñez, Berta ; Salgado, Esteban ; Visus, Ignacio ; Barrado, Marta ; Teijeira, Lucia ; Martinez, Enrique ; Vera, Ruth
Objectives : To describe the Quality of Life (QOL) of breast-cancer patients diagnosed with COVID-19 and analyse its evolution, compare the QOL of these patients according to the COVID-19 wave in which they were diagnosed, and examine the clinical and demographic determinants of QOL. Methods : A total of 260 patients with breast cancer (90.8% I-III stages) and COVID-19 (85% light/moderate) were included (February-September 2021) in this study. Most patients were receiving anticancer treatment [...]
Is virtual nutritional counseling efficacious for cancer patients during the COVID-19 pandemic?
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Is virtual nutritional counseling efficacious for cancer patients during the COVID-19 pandemic?
Baş, Dilşat ; Sönmez, Özlem ; Koç, Elif Sitre ; Celayir, Özde Melisa ; Hajhamidiasl, Ladan ; Tontaş, Ebru
This study investigates the outcomes of virtual nutritional counseling (VNC) for oncology patients during the Covid-19 pandemic. Our study evaluated the nutritional status data of cancer patients at the baseline and after VNC. An oncology dietitian evaluated the patients by video calling each patient via WhatsApp and sent an individual nutrition diet plan and recommendations via e-mail. Patient-Generated Subjective Global Assessment (PG-SGA) was used as a screening and evaluation tool to assess [...]
Delayed diagnosis resulting in increased disease burden in multiple myeloma: the legacy of the COVID-19 pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Delayed diagnosis resulting in increased disease burden in multiple myeloma: the legacy of the COVID-19 pandemic
Carmichael, Jonathan ; Seymour, Frances ; McIlroy, Graham ; Tayabali, Sarrah ; Amerikanou, Rosie ; Feyler, Sylvia ; Popat, Rakesh ; Pratt, Guy ; Parrish, Christopher ; Ashcroft, A. John ; Jackson, Graham H. ; Cook, Gordon
The COVID-19 pandemic has had global healthcare impacts, including high mortality from SARS-CoV-2 infection in cancer patients; individuals with multiple myeloma (MM) are especially susceptible to poor outcomes. However, even for MM patients who avoided severe infection, the ramifications of the pandemic have been considerable. The consequences of necessary socio-geographical behavior adaptation, including prolonged shielding and interruptions in delivery of non-pandemic medical services are [...]
The COVID - AGICT study: COVID–19 and advanced gastro-intestinal cancer surgical treatment. A multicentric Italian study on the SARS-CoV-2 pandemic...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
The COVID - AGICT study: COVID–19 and advanced gastro-intestinal cancer surgical treatment. A multicentric Italian study on the SARS-CoV-2 pandemic impact on gastro-intestinal cancers surgical treatment during the 2020. Analysis of perioperative and short-term oncological outcomes
Giuliani, Giuseppe ; Guerra, Francesco ; Messinese, Simona ; Santelli, Francesco ; Salvischiani, Lucia ; Esposito, Sofia ; Ferraro, Luca ; Esposito, Alessandro ; De Pastena, Matteo ; Rega, Daniela ; Delrio, Paolo ; La Raja, Carlotta ; Spinelli, Antonino ; Massaron, Simonetta ; De Nardi, Paola ; Kauffmann, Emanuele Federico ; Boggi, Ugo ; Deidda, Simona ; Restivo, Angelo ; Marano, Alessandra ; Borghi, Felice ; Piccoli, Micaela ; Depalma, Norma ; D'Ugo, Stefano ; Spampinato, Marcello ; Cozzani, Federico ; Del Rio, Paolo ; Marcellinaro, Rosa ; Carlini, Massimo ; De Rosa, Raffaele ; Scabini, Stefano ; Maiello, Fabio ; Polastri, Roberto ; Turri, Giulia ; Pedrazzani, Corrado ; Zese, Monica ; Parini, Dario ; Casaril, Andrea ; Moretto, Gianluigi ; De Leo, Antonio ; Catarci, Marco ; Trapani, Renza ; Zonta, Sandro ; Marsanic, Patrizia ; Muratore, Andrea ; Di Franco, Gregorio ; Morelli, Luca ; Coppola, Alessandro ; Caputo, Damiano ; Andreuccetti, Jacopo ; Pignata, Giusto ; Mastrangelo, Laura ; Jovine, Elio ; Mazzola, Michele ; Ferrari, Giovanni ; Mariani, Lorenzo ; Ceccarelli, Graziano ; Giuseppe, Rocco ; Bolzon, Stefano ; Grasso, Mariateresa ; Testa, Silvio ; Germani, Paola ; de Manzini, Nicolò ; Langella, Serena ; Ferrero, Alessandro ; Coletta, Diego ; Bianchi, Paolo Pietro ; Bengala, Carmelo ; Coratti, Andrea ; Franco, Lorenzo De ; Benigni, Roberto ; Tribuzi, Angela ; Marra, Ubaldo ; Di Marino, Michele ; Cova, Chiara ; Bianchi, Beatrice ; Nobile, Sara ; Zorcolo, Luigi ; Lisi, Giorgio ; Allisiardi, Fabrizio ; Grieco, Michele ; Righetti, Carolina ; Frisini, Marco ; Brolese, Alberto ; Grassia, Michele ; Lucchi, Andrea ; Bagaglini, Giulia ; Sica, Giuseppe S. ; Manara, Michele ; Turati, Luca ; Macone, Lorenzo ; Carminati, Roberta ; Mariani, Pierpaolo ; Rizzo, Gianluca ; Coco, Claudio ; Pennella, Francesca Pennetti ; Rondelli, Fabio ; Romano, Lucia ; Giuliani, Antonio ; Palaia, Raffaele ; Belli, Andrea ; Albino, Vittorio ; Leongito, Maddalena ; David, Giulia ; Misitano, Pasquale ; Pasulo, Silvia ; Baiocchi, Gian Luca ; La Mendola, Roberta ; Hilal, Mohamnad Abu ; Baldari, Ludovica ; Cassinotti, Elisa ; Boni, Luigi ; Capolupo, Gabriella Teresa ; Caricato, Marco ; Pinotti, Enrico ; Montuori, Mauro ; Bombardini, Cristina ; Anania, Gabriele ; Dibra, Rigers ; Martines, Gennaro ; Solaini, Leonardo ; Ercolani, Giorgio ; Oliva, Renato ; Carati, Maria Vittoria ; Grazi, Gian Luca ; Ghio, Giacomo ; Marchegiani, Francesco ; Pucciarelli, Salvatore ; La Torre, Filippo ; Iannone, Immacolata ; Krizzuk, Dimitri ; Sammartino, Francesco ; Catalano, Giorgia ; Strignano, Paolo ; Romagnoli, Renato ; Piccione, Domenico ; Nardo, Bruno ; Reddavid, Rossella ; Degiuli, Maurizio ; Gerosa, Martino ; Maggioni, Dario ; Zuolo, Michele ; Rigamonti, Marco ; Ghazouani, Omar ; Galleano, Raffaele ; Percivale, Andrea ; Tirloni, Luca ; Moraldi, Luca ; Fabbri, Nicolò ; Feo, Carlo Vittorio ; Colombo, Samuele ; Di Saverio, Salomone ; Barbato, Giuseppe ; Coratti, Francesco ; Sagnotta, Andrea ; Mancini, Stefano ; Formisano, Giampaolo
Background : This Italian multicentric retrospective study aimed to investigate the possible changes in outcomes of patients undergoing surgery for gastrointestinal cancers during the COVID-19 pandemic. Method : Our primary endpoint was to determine whether the pandemic scenario increased the rate of patients with colorectal, gastroesophageal, and pancreatic cancers resected at an advanced stage in 2020 compared to 2019. Considering different cancer staging systems, we divided tumors into early [...]
The stage of head and neck diagnosed malignancies in COVID-19 outbreak versus before outbreak: A retrospective study
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
The stage of head and neck diagnosed malignancies in COVID-19 outbreak versus before outbreak: A retrospective study
Jahanshahi, Fatemeh ; Asadi, Mahboobe ; Movahedi, Alireza
Background : Global COVID-19 pandemic has affected cancer care systems. Recent studies show that the number of cases diagnosed with cancer has drastically decreased compared to the same period before the pandemic. Therefore, we are confronted with delayed diagnosis of critical cancers. Aim The aim of this study is to investigate whether the stage of known cancers has been affected by delayed diagnosis and to compare the stages of head and neck cancers diagnosed during and before the pandemic. [...]
Rate of COVID-19 vaccination among patients with cancer who tested positive for severe acute respiratory syndrome-coronavirus 2: Analysis of the Am...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Rate of COVID-19 vaccination among patients with cancer who tested positive for severe acute respiratory syndrome-coronavirus 2: Analysis of the American Society of Clinical Oncology Registry
Kurbegov, Dax ; Bruinooge, Suanna S. ; Lei, Xiudong Jennifer ; Kirkwood, M. Kelsey ; Dickson, Natalie ; Hattiangadi, Trupti ; Mileham, Kathryn F. ; Patrick, Alicia ; Williams, Jen Hanley ; Kaltenbaugh, Melinda ; Gralow, Julie R. ; Garrett-Mayer, Elizabeth
Objectives: Atezolizumab monotherapy has marketing authorisation by the Medicines and Healthcare products Regulatory Agency as adjuvant treatment following complete resection for adults with stage II–IIIA non-small cell lung cancer (NSCLC) whose tumours have PD-L1 expression on ≥ 50% of tumour cells and whose disease has not progressed following adjuvant platinum-based chemotherapy. This study evaluated the cost-effectiveness of atezolizumab vs best supportive care (BSC) in the licensed patient [...]
Outcomes of SARS-CoV-2 infection in Ph-neg chronic myeloproliferative neoplasms: results from the EPICOVIDEHA registry
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Outcomes of SARS-CoV-2 infection in Ph-neg chronic myeloproliferative neoplasms: results from the EPICOVIDEHA registry
Marchetti, Monia ; Salmanton-García, Jon ; El-Ashwah, Shaimaa ; Verga, Luisa ; Itri, Federico ; Racil, Zdenek ; Davila-Valls, Julio ; Martin-Perez, Sonia ; Van Doesum, Jaap ; Passamonti, Francesco ; Abu-Zeinah, Ghaith ; Farina, Francesca ; Lopez-Garcia, Alberto ; Dragonetti, Giulia ; Cattaneo, Chiara ; Gomes Da Silva, Maria ; Bilgin, Yavuz M. ; Žák, Pavel ; Petzer, Verena ; Glenthøj, Andreas ; Espigado, Ildefonso ; Buquicchio, Caterina ; Bonuomo, Valentina ; Prezioso, Lucia ; Meers, Stef ; Duarte, Rafael ; Bergantim, Rui ; Jaksic, Ozren ; Čolović, Natasha ; Blennow, Ola ; Cernan, Martin ; Schonlein, Martin ; Samarkos, Michail ; Mitra, Maria Enza ; Magliano, Gabriele ; Maertens, Johan ; Ledoux, Marie-Pierre ; Jiménez, Moraima ; Demirkan, Fatih ; Collins, Graham P. ; Cabirta, Alba ; Gräfe, Stefanie K. ; Nordlander, Anna ; Wolf, Dominik ; Arellano, Elena ; Cordoba, Raul ; Hanakova, Michaela ; Zambrotta, Giovanni Paolo Maria ; Nunes Rodrigues, Raquel ; Limberti, Giulia ; Marchesi, Francesco ; Cornely, Oliver A. ; Pagano, Livio
Background:Patients with Philadelphia-negative chronic myeloproliferative neoplasms (MPN) typically incur high rates of infections and both drugs and comorbidities may modulate infection risk.Objectives:The present study aims to assess the effect of immunosuppressive agents on clinical outcomes of MPN patients affected by the coronavirus disease 2019 (COVID-19). Design:This is an observational study. Methods:We specifically searched and analyzed MPN patients collected by EPICOVIDEHA online [...]
Functional humoral and cellular response of monovalent COVID-19-vaccines against Omicron BA.2 variant of SARS-CoV-2 in patients with chronic lympho...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Functional humoral and cellular response of monovalent COVID-19-vaccines against Omicron BA.2 variant of SARS-CoV-2 in patients with chronic lymphocytic leukemia
Passerini, Matteo ; Ratishvili, Tamar ; Monroe, Jonathon M. ; Temesgen, Zelalem ; Witzig, Thomas E. ; Kay, Neil E. ; Kennedy, Richard B. ; Parikh, Sameer A.
We designed a prospective study to evaluate the humoral (using a surrogate virus neutralization test) and cellular (using an IFN-? ELISpot) immune response among patients with chronic lymphocytic leukemia (CLL) against Wuhan-Hu-1 and Omicron BA.2 strains of SARS-CoV-2, after mRNA-based vaccination. The proportion of patients with a functional humoral response was higher among untreated CLL patients compared to treated CLL patients against both Wuhan-Hu-1 and Omicron BA.2 after the second and [...]
Menée à partir de données portant sur 1 291 adolescentes et jeunes adultes atteintes d'un cancer pendant leur grossesse (âge : 15-39 ans), cette étude analyse la prévalence de complications lors des naissances
Adverse birth outcomes of adolescent and young adult women diagnosed with cancer during pregnancy
Menée à partir de données portant sur 1 291 adolescentes et jeunes adultes atteintes d'un cancer pendant leur grossesse (âge : 15-39 ans), cette étude analyse la prévalence de complications lors des naissances
Adverse birth outcomes of adolescent and young adult women diagnosed with cancer during pregnancy
Betts, Andrea C ; Shay, L Aubree ; Lupo, Philip J ; Pruitt, Sandi L ; Roth, Michael E ; Allicock, Marlyn A ; Cohn, Barbara A ; Murphy, Caitlin C
Background : We examined adverse birth outcomes among adolescent and young adult women diagnosed with cancer (AYA women, ages 15-39 years) during pregnancy. Methods : We linked data from the Texas Cancer Registry, vital records, and Texas Birth Defects Registry to identify all singleton births to AYA women diagnosed during pregnancy from January 1999 to December 2016. We compared prevalence of adverse live birth outcomes between AYA women and women without cancer (matched 1:4 on age, race and [...]
Menée en Chine à partir de données portant sur 287 408 femmes ayant déclaré n'avoir jamais fumé (âge : 30-79 ans ; durée médiane de suivi : 10,3 ans), cette étude de cohorte prospective évalue l'association entre des facteurs hormonaux et reproductifs et la mortalité par cancer du poumon (814 décès)
Female reproductive and hormonal factors and lung cancer mortality among never-smokers: a prospective cohort study of 287 408 Chinese women
Menée en Chine à partir de données portant sur 287 408 femmes ayant déclaré n'avoir jamais fumé (âge : 30-79 ans ; durée médiane de suivi : 10,3 ans), cette étude de cohorte prospective évalue l'association entre des facteurs hormonaux et reproductifs et la mortalité par cancer du poumon (814 décès)
Female reproductive and hormonal factors and lung cancer mortality among never-smokers: a prospective cohort study of 287 408 Chinese women
Cheng, Elvin S ; Velentzis, Louiza S ; Weber, Marianne ; Steinberg, Julia ; Canfell, Karen ; Yu, Xue Qin
There is growing, but inconsistent evidence suggesting oestrogen may play a key role in lung cancer development, especially among never-smoking women for whom lung cancer risk factors remain largely elusive. Using the China Kadoorie Biobank, a large-scale prospective cohort with 302 510 women aged 30-79 years recruited from ten regions in China during 2004-2008, we assessed the risk of lung cancer death among self-reported never-smoking women who were cancer-free at baseline, in relation to age [...]
Menée en Corée à partir de données 2010-2020 portant sur 21 978 patients atteints d'un cancer du poumon non à petites cellules (âge médian au diagnostic : 64,1 ans), cette étude de cohorte analyse l'évolution du taux de survie à 3 ans
Trends in Survival Rates of Non–Small Cell Lung Cancer With Use of Molecular Testing and Targeted Therapy in Korea, 2010-2020
Menée en Corée à partir de données 2010-2020 portant sur 21 978 patients atteints d'un cancer du poumon non à petites cellules (âge médian au diagnostic : 64,1 ans), cette étude de cohorte analyse l'évolution du taux de survie à 3 ans
Trends in Survival Rates of Non–Small Cell Lung Cancer With Use of Molecular Testing and Targeted Therapy in Korea, 2010-2020
Chi, Sang Ah ; Yu, Hyeyeon ; Choi, Yoon-La ; Park, Sehhoon ; Sun, Jong-Mu ; Lee, Se-Hoon ; Ahn, Jin Seok ; Ahn, Myung-Ju ; Choi, Dae-Ho ; Kim, Kyunga ; Jung, Hyun Ae ; Park, Keunchil
Importance : Over the past 10 years, treatment of non–small cell lung cancer (NSCLC) has been continually revolutionized. However, standard clinical trials may not reflect current multiple lines of treatment and corresponding outcomes in a timely manner. Objective : To investigate outcomes associated with new treatment of NSCLC in a clinical setting. Design, Setting, and Participants : This cohort study included patients with NSCLC between January 1, 2010, and November 30, 2020, who received [...]
Cette étude passe en revue les données d'incidence du cancer de la vessie et de la mortalité associée et examine les principaux facteurs de risque de la maladie
Global trends in the epidemiology of bladder cancer: challenges for public health and clinical practice
Cette étude passe en revue les données d'incidence du cancer de la vessie et de la mortalité associée et examine les principaux facteurs de risque de la maladie
Global trends in the epidemiology of bladder cancer: challenges for public health and clinical practice
van Hoogstraten, Lisa M. C. ; Vrieling, Alina ; van der Heijden, Antoine G. ; Kogevinas, Manolis ; Richters, Anke ; Kiemeney, Lambertus A.
Bladder cancer is among the ten most common cancers globally, causes considerable morbidity and mortality and is, therefore, a substantial burden for health-care systems. The incidence of bladder cancer is affected by demographic trends, most notably population growth and ageing, as well as exposure to risk factors, especially tobacco smoking. Consequently, the incidence has not been stable throughout the world over time, nor will it be in the near future. Further primary prevention efforts are [...]
Analyses économiques et systèmes de soins (2)
Menée au Royaume-Uni à partir de données issues de 870 réunions de concertation pluridisciplinaire (RCP) portant sur 145 patientes atteintes d'un cancer de l'ovaire de stade avancé, cette étude multicentrique analyse l'influence des RCP sur les choix thérapeutiques et les disparités géographiques
MDT practice determines treatment pathway for patients with advanced ovarian cancer: A multi-centre observational study
Menée au Royaume-Uni à partir de données issues de 870 réunions de concertation pluridisciplinaire (RCP) portant sur 145 patientes atteintes d'un cancer de l'ovaire de stade avancé, cette étude multicentrique analyse l'influence des RCP sur les choix thérapeutiques et les disparités géographiques
MDT practice determines treatment pathway for patients with advanced ovarian cancer: A multi-centre observational study
Khassan, T. ; Smitten, E. ; Wood, N. ; Fotopoulou, C. ; Morrison, J. ; MacDonald, M. ; Baxter, K. ; Edmondson, R. J.
Objective: To investigate decision making for patients with advanced ovarian cancer as a possible explanation of geographical variation in treatment patterns. Methods: We carried out a multi-centre observational study in multidisciplinary teams meetings for five major UK cancer centres. All patients presenting to five cancer centres with advanced ovarian cancer over a six-week period. The GO-MDT-MODe tool was used to provide a measure of participation and quality of case discussion for all [...]
Menée dans un contexte britannique, cette étude analyse le rapport coût-efficacité de l'atézolizumab en traitement adjuvant chez des patients atteints d'un cancer du poumon non à petites cellules de stade II-IIIA surexprimant PD-L1
Cost-effectiveness analysis of adjuvant atezolizumab in stage II-IIIA non-small cell lung cancer expressing ≥ 50% PD-L1: A United Kingdom health ca...
Menée dans un contexte britannique, cette étude analyse le rapport coût-efficacité de l'atézolizumab en traitement adjuvant chez des patients atteints d'un cancer du poumon non à petites cellules de stade II-IIIA surexprimant PD-L1
Cost-effectiveness analysis of adjuvant atezolizumab in stage II-IIIA non-small cell lung cancer expressing ≥ 50% PD-L1: A United Kingdom health care perspective
Yip, Chui-ying ; Greystoke, Alastair ; Abogunrin, Seye ; Belleli, Rossella ; Di Maio, Danilo ; Rouse, Peter ; Jovanoski, Nick
Objectives: Atezolizumab monotherapy has marketing authorisation by the Medicines and Healthcare products Regulatory Agency as adjuvant treatment following complete resection for adults with stage II–IIIA non-small cell lung cancer (NSCLC) whose tumours have PD-L1 expression on ≥ 50% of tumour cells and whose disease has not progressed following adjuvant platinum-based chemotherapy. This study evaluated the cost-effectiveness of atezolizumab vs best supportive care (BSC) in the licensed patient [...]