Menée à partir de données 1992-2017 de "The American Cancer Society Cancer Prevention Study-II Nutrition Cohort" portant sur 108 002 personnes, cette étude analyse l'association entre une exposition résidentielle aux polluants atmosphériques (PM2.5, PM10, PM10-2.5, NO2, O3, SO2 et CO) et le risque de cancer hématologique (2 659 cas)

Outdoor air pollution and risk of incident adult haematologic cancer subtypes in a large US prospective cohort

Diver, W. Ryan ; Teras, Lauren R. ; Deubler, Emily L. ; Turner, Michelle C.

Background: Outdoor air pollution and particulate matter (PM) are classified as Group 1 human carcinogens for lung cancer. Pollutant associations with haematologic cancers are suggestive, but these cancers are aetiologically heterogeneous and sub-type examinations are lacking. Methods: The American Cancer Society Cancer Prevention Study-II Nutrition Cohort was used to examine associations of outdoor air pollutants with adult haematologic cancers. Census block group level annual predictions of [...]

Menée auprès de 172 284 personnes (79 % d'hommes ; durée de suivi : 14 ans), cette étude analyse l'association entre le score "Life's Essential 8" (LE8) évaluant la santé cardiovasculaire et le risque de cancer (5 060 cas) ou de décès

Association of Life's Essential 8 with all-cause mortality and risk of cancer: a prospective cohort study

Jiang, Jinguo ; Ning, Ning ; Liu, Yang ; Cai, Zhiwei ; Zhao, Maoxiang ; Peng, Xinyi ; Li, Liuxin ; Chen, Shuohua ; Wang, Jing ; Wang, Feng ; Qin, Xueying ; Ma, Yanan ; Wu, Shouling

Background: No study has concentrated on the association of LE8 with cancer risk and death. We aim to examine the association of LE8 with death and cancer. Methods: A total of 94733 adults aged 51.42 ± 12.46 years and 77551 participants aged 54.09±12.06 years were enrolled in longitudinal and trajectory analysis respectively. Baseline LE8 was divided into three groups based on the American Heart Association criteria and three trajectory patterns by latent mixture models. We reviewed medical [...]

Menée à partir de données de l'Assurance maladie taïwanaise portant sur près de 3 millions de personnes (durée de suivi : 12 ans), cette étude analyse le risque de cancer chez des personnes souffrant de diabète

Diabetes and further risk of cancer: a nationwide population-based study

Chang, Wei-Chuan ; Hsieh, Tsung-Cheng ; Hsu, Wen-Lin ; Chang, Fang-Ling ; Tsai, Hou-Ren ; He, Ming-Shan

Background: Individuals with diabetes have a significantly higher risk of developing various forms of cancer, and the potential biological links between these two diseases are not completely understood. Methods: This was a longitudinal retrospective nationwide cohort study, a study design that allows us to examine the natural course of cancer development over an extended period of time with a large sample size. Initially, 3,111,975 and 22,208,395 eligible patients aged ≥ 20 years with and [...]

A partir d'une revue systématique de la littérature publiée jusqu'en juin 2021 (18 études), cette étude examine les variants et les gènes associés au risque de second cancer chez les adultes ayant survécu à un cancer pédiatrique

Genetic risk of second malignant neoplasm after childhood cancer treatment: A systematic review

Ducos, Claire ; Aba, Naïla ; Rosselli, Filippo ; Fresneau, Brice ; Al Ahmad Nachar, Baraah ; Zidane, Monia ; de Vathaire, Florent ; Benhamou, Simone ; Haddy, Nadia

Second malignant neoplasm (SMN) is one of the most severe long-term risks for childhood cancer survivors (CCS), significantly impacting long-term patient survival. While radiotherapy and chemotherapy are known risk factors, the observed inter-individual variability suggests a genetic component contributing to the risk of SMN. This article aims to conduct a systematic review of genetic factors implicated in the SMN risk among CCS. Searches were performed in PubMed, Scopus, and Web of Sciences. [...]

Menée à l'aide de données de la "Women’s Health Initiative (WHI)", cette étude analyse l'association entre une infertilité et le risque de cancer colorectal après la ménopause (2 680 cas)

History of infertility and risk of colorectal cancer

Farland, Leslie V. ; Lind, Kimberly E. ; Roe, Denise J. ; Saquib, Nazmus ; Strickler, Howard D. ; Qi, Lihong ; Thomson, Cynthia A. ; Harris, Holly R.

Background: There has been limited prior research on the association between infertility and risk of colorectal cancer. Methods: Data from postmenopausal women in Women’s Health Initiative (WHI) were used to estimate the association between self-reported infertility (twelve months of trying to get pregnant without achieving a pregnancy) with risk of colorectal cancer using Cox proportional hazard models. Results: No association was observed between infertility and risk of postmenopausal [...]