Menée aux Etats-Unis à partir de données portant sur 5 366 patients ayant survécu à un cancer (âge moyen : 59,8 ans), cette étude analyse leur qualité de vie en fonction de leur origine ethnique et de leur pays d'origine

Addressing health-related quality of life inequities in cancer: where do we go from here?

Pinheiro, Laura C ; Rosenberg, Shoshana

In 2019, the National Cancer Institute (NCI) hosted a cancer survivorship workshop with the goal of identifying specific evidence gaps in cancer survivorship.1 Prioritized among these gaps was improving the understanding of and addressing patient-reported physical, psychosocial, and financial needs of cancer survivors from diverse racial and ethnic backgrounds, as well as countries of origin. Optimizing health-related quality (HRQOL), defined as “a multidomain concept that represents the [...]

Menée aux Etats-Unis à partir de données portant sur 5 366 patients ayant survécu à un cancer (âge moyen : 59,8 ans), cette étude analyse leur qualité de vie en fonction de leur origine ethnique et de leur pays d'origine

Health-Related Quality of Life by Race, Ethnicity, and Country of Origin among Cancer Survivors

Reeve, Bryce B ; Graves, Kristi D ; Lin, Li ; Potosky, Arnold L ; Ahn, Jaeil ; Henke, Debra M ; Pan, Wei ; Fall-Dickson, Jane M

Background: Typical cancer research studies of health-related quality of life (HRQOL) in the United States do not include country of origin when examining race and ethnic group differences. This population-based, cross-sectional study used an innovative methodology to examine how self-reported racial and ethnic groups, by country of origin, report differential HRQOL experiences after adjusting for clinical and demographic characteristics including socio-economic status. Methods: Recruited from [...]

Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19

How the COVID-19 pandemic has affected eating habits and physical activity in breast cancer survivors: the DianaWeb study

Acito, Mattia ; Rondini, Tommaso ; Gargano, Giuliana ; Moretti, Massimo ; Villarini, Milena ; Villarini, Anna

Purpose: Breast cancer (BC) survivors are increasingly interested in learning about healthy lifestyles to reduce the risk of BC recurrence and mortality. The DianaWeb study, a community-based participatory research, offers BC patients a specific interactive website to help them in adopting and maintain correct lifestyles, in line with World Cancer Research Fund recommendations. However, to limit the spread of the COVID-19 pandemic, most countries introduced restrictions which, inevitably, [...]

Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19

COVID-19 Incidence and Mortality in Patients Operated on for Breast Cancer. Comparison with the General Population

Barco, Israel ; Chabrera, Carolina ; García-Fernández, Antonio ; Fraile, Manel ; Vidal, Carmen ; Mitru, Claudia Beatriz ; Porta, Oriol ; García-Font, Marc

Background: Breast Cancer (BC) remains the most diagnosed malignancy and the most common cause of cancer-related mortality in women worldwide. Covid-19 mortality in BC patients has been linked to comorbid conditions rather than to cancer treatment itself, although this was not confirmed by a meta-analysis. Also, during Covid-19 outbreaks, a great deal of health care resources is reassigned to critical Covid-19 patients. Patients and Methods: During 5 consecutive trimesters (from 1/12/2020 to [...]

Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19

Telehealth in cancer care during the COVID-19 pandemic

Burbury, Kate ; Brooks, Peter ; Gilham, Leslie ; Solo, Ilana ; Piper, Amanda ; Underhill, Craig ; Campbell, Philip ; Blum, Robert ; Brown, Stephen ; Barnett, Frances ; Torres, Javier ; Wang, Xiaofang ; Poole, William ; Grobler, Anneke ; Johnston, Genevieve ; Beer, Cassandra ; Cross, Hannah ; Wong, Zee Wan

Introduction: The Victorian COVID-19 Cancer Network (VCCN) Telehealth Expert Working Group aimed to evaluate the telehealth (TH) experience for cancer patients, carers and clinicians with the rapid uptake of TH in early 2020 during the COVID-19 pandemic. Methods: We conducted a prospective multi-centre cross-sectional survey involving eight Victorian regional and metropolitan cancer services and three consumer advocacy groups. Patients or their carers and clinicians who had TH consultations [...]

Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19

Humoral and Cellular Immune Responses against SARS-CoV-2 after Third Dose BNT162b2 following Double-Dose Vaccination with BNT162b2 versus ChAdOx1 in Patients with Cancer

Debie, Yana ; Van Audenaerde, Jonas R.M. ; Vandamme, Timon ; Croes, Lieselot ; Teuwen, Laure-Anne ; Verbruggen, Lise ; Vanhoutte, Greetje ; Marcq, Elly ; Verheggen, Lisa ; Le Blon, Debbie ; Peeters, Bart ; Goossens, Maria E. ; Pannus, Pieter ; Ariën, Kevin K. ; Anguille, Sébastien ; Janssens, Annelies ; Prenen, Hans ; Smits, Evelien L.J. ; Vulsteke, Christof ; Lion, Eva ; Peeters, Marc ; van Dam, Peter A.

Purpose: Patients with cancer display reduced humoral responses after double-dose COVID-19 vaccination, whereas their cellular response is more comparable with that in healthy individuals. Recent studies demonstrated that a third vaccination dose boosts these immune responses, both in healthy people and patients with cancer. Because of the availability of many different COVID-19 vaccines, many people have been boosted with a different vaccine from the one used for double-dose vaccination. Data [...]

Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19

Financial hardship and mental health among cancer survivors during the COVID-19 pandemic: An analysis of the US COVID-19 Household Impact Survey

Islam,Jessica Y. ; Turner,Kea ; Saeb,Huda ; Powell,Margaux ; Dean,Lorraine T. ; Camacho-Rivera,Marlene

Purpose: Our objective was to (1) identify associated characteristics of financial hardship (FH), and (2) evaluate associations of FH with mental health symptoms among cancer survivors during the COVID-19 pandemic. Methods: Using data from the nationally representative COVID-19 Impact Survey, we defined cancer survivors as those with a self-reported diagnosis of cancer (n = 854,7.6%). We defined FH using the following question: "Based on your current financial situation, how would you pay for [...]

Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19

BRAF inhibitor treatment of classical hairy cell leukemia allows successful vaccination against SARS-CoV-2

Konrat, Judith ; Rösler, Wiebke ; Roiss, Michael ; Meier-Abt, Fabienne ; Widmer, Corinne C. ; Balabanov, Stefan ; Manz, Markus G. ; Zenz, Thorsten

In classical hairy cell leukemia (HCL), standard treatments including purine analogs achieve a durable response (up to 90%), but lead to severe immunosuppression and long-lasting depletion of CD4 + T lymphocytes. The BRAF inhibitor vemurafenib is effective in HCL, but its use in first-line treatment is restricted to select clinical situations (e.g. active infection). Its impact on immune function or response to vaccines in HCL is unclear. We treated four HCL patients with vemurafenib during the [...]

Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19

Japanese cancer screening programs during the COVID-19 pandemic: Changes in participation between 2017-2020

Machii, Ryoko ; Takahashi, Hirokazu

Background :The impact of the coronavirus disease 2019 (COVID-19) pandemic on cancer screening participation is a global concern. A national database of screening performance is available in Japan for population-based cancer screening, estimated to cover approximately half of all cancer screenings. Methods: Utilizing the fiscal year (FY) 2017–2020 national database, the number of participants in screenings for gastric cancer (upper gastrointestinal [UGI] series or endoscopy), colorectal cancer [...]

Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19

Long-term effects of the interruption of the Dutch breast cancer screening program due to COVID-19: A modelling study

Poelhekken, Keris ; Greuter, Marcel J. W. ; de Munck, Linda ; Siesling, Sabine ; Brokken, Frank B. ; de Bock, Geertruida H.

Due to COVID-19, the Dutch breast cancer screening program was interrupted for three months with uncertain long-term effects. The aim of this study was to estimate the long-term impact of this interruption on delay in detection, tumour size of screen-detected breast cancers, and interval cancer rate. After validation, the micro-simulation model SiMRiSc was used to calculate the effects of interruption of the breast cancer screening program for three months and for hypothetical interruptions of [...]

Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19

Prevention and treatment of COVID-19 in patients with benign and malignant blood disorders

Saade, Elie A. ; Hojat, Leila S. ; Gundelly, Praveen ; Salata, Robert A.

Patients with moderate to severe immunosuppression, a condition that is common in many hematologic diseases because of the pathology itself or its treatment, are at high risk for COVID-19 and its complications. While empirical data are sometimes conflicting, this heightened risk has been confirmed in multiple well-done studies for patients with hematologic malignancies, particularly those with B-cell lymphoid malignancies who received lymphocytotoxic therapies, those with a history of recent [...]

Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19

Dying with Cancer and COVID-19, with Special Reference to Lung Cancer: Frailty as a Risk Factor

Strang, Peter ; Schultz, Torbjörn

Frailty has been strongly associated with deaths from COVID-19 in the general population, especially in the elderly, but it is rarely studied in the context of cancer. In this study of 4312 patients who died with cancer, of whom 282 also had concomitant COVID-19, we found that established risk factors, such as older age, male gender, and being a nursing home resident, were also significant risk factors for patients with cancer. Among the risk factors, frailty, as measured using the Hospital [...]

Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19

Impact of coronavirus disease 2019 on the number of newly diagnosed cancer patients and examinations and surgeries performed for cancer in Japan: a nationwide study

Terashima, Takeshi ; Konishi, Hiroshi ; Sato, Yasunori ; Igarashi, Muneki ; Yanagibashi, Takafumi ; Konno, Ryo ; Saya, Hideyuki ; Doki, Yuichiro ; Kakizoe, Tadao

Background: The coronavirus disease 2019 (COVID-19) pandemic has rapidly and dramatically influenced healthcare across Japan. However, the influence of the COVID-19 pandemic on the number of newly diagnosed cancer, surgical treatment, and diagnostic examination for cancer types have not been completely investigated all over Japan. This study aimed to analyze the number of cases before and during the COVID-19 pandemic. Methods: This retrospective study was a survey that asked to provide the [...]

Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19

Lymphadenopathies before and during the Pandemic COVID-19: Increasing Incidence of Metastases from Solid Tumors

Trasarti, Stefania ; Troiano, Raffaele ; Biglietto, Mario ; Sorella, Silvia ; Lisi, Chiara ; Assanto, Giovanni Manfredi ; Bizzoni, Luisa ; Brunetti, Gregorio Antonio ; Giordano, Carla ; Rullo, Emma ; Saracino, Mariangela ; Saullo, Paolina ; Vignetti, Marco ; Martelli, Maurizio ; Caronna, Roberto

Since December 2019, the world has experienced a pandemic caused by SARS-CoV-2, a virus which spread throughout the world. Anti-COVID19 measures were applied to limit the spread of the infection, affecting normal clinical practice. In 2020, studies on the possible impact of the pandemic considering the screening programs for early diagnosis of cancer were conducted, resulting in a prediction of delayed diagnosis of cancer. We performed a retrospective monocentric study on patients who present [...]

Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19

SARS-CoV-2 primary and breakthrough infections in patients with cancer: Implications for patient care

Wang, Lindsey ; Wang, William ; Xu, Rong ; Berger, Nathan A.

Initial reports of SARS-CoV-2 caused COVID-19 suggested that patients with malignant diseases were at increased risk for infection and its severe consequences. In order to provide early United States population-based assessments of SARS-CoV-2 primary infections in unvaccinated patients with hematologic malignancies or cancer, and SARS-CoV-2 breakthrough infections in vaccinated patients with hematologic malignancies or cancer, we conducted retrospective studies using two, unique nationwide [...]

Menée aux Pays-Bas à partir de données portant sur 2 003 adultes ayant survécu à un cancer pédiatrique (âge moyen lors de l'étude : 33,1 ans), cette étude de cohorte analyse les facteurs associés au risque de densité minérale osseuse faible et très faible ainsi qu'au risque de fracture

Long-term bone health in childhood cancer survivors: underappreciated and undertreated?

Link-Rachner, Cornelia S. ; Rachner, Tilman D.

Maintenance of bone quality is an ongoing challenge throughout the lifespan of a cancer survivor. Although bone metastases are the most obvious scenario in which a malignancy negatively affects bone, non-metastatic cancer can also impair bone metabolism by direct (eg, cancer mediated) or indirect (eg, treatment or consequences of such) mechanisms. 1 Updated American Society of Clinical Oncology (ASCO) clinical practice guidelines were published in 2019 to provide guidance on how to monitor and [...]

Menée aux Pays-Bas à partir de données portant sur 2 003 adultes ayant survécu à un cancer pédiatrique (âge moyen lors de l'étude : 33,1 ans), cette étude de cohorte analyse les facteurs associés au risque de densité minérale osseuse faible et très faible ainsi qu'au risque de fracture

Risk and determinants of low and very low bone mineral density and fractures in a national cohort of Dutch adult childhood cancer survivors (DCCSS-LATER): a cross-sectional study

van Atteveld, Jenneke E. ; de Winter, Demi T. C. ; Pluimakers, Vincent G. ; Fiocco, Marta ; Nievelstein, Rutger A. J. ; Hobbelink, Monique G. G. ; de Vries, Andrica C. H. ; Loonen, Jacqueline J. ; van Dulmen-den Broeder, Eline ; van der Pal, Helena J. ; Pluijm, Saskia M. F. ; Kremer, Leontien C. M. ; Ronckers, Cecile M. ; van der Heiden-van der Loo, Margriet ; Versluijs, A. Birgitta ; Louwerens, Marloes ; Bresters, Dorine ; van Santen, Hanneke M. ; Olsson, Daniel S. ; Hoefer, Imo ; van den Berg, Sjoerd A. A. ; den Hartogh, Jaap ; Tissing, Wim J. E. ; Neggers, Sebastian J. C. M. M. ; van den Heuvel-Eibrink, Marry M.

Background : Childhood cancer survivors are at risk of developing skeletal comorbidities later in life. We aimed to assess risk factors for low and very low bone mineral density (BMD), and the risk of and risk factors for any fractures and vertebral fractures in a national cohort of Dutch adult childhood cancer survivors. Methods : In this cross-sectional study, we used data from the DCCSS LATER cohort, which comprised individuals who were alive for at least 5 years after diagnosis of childhood [...]

Menée à partir des données GLOBOCAN portant sur 185 pays et territoires, cette étude présente pour l'année 2020 une estimation de l'incidence du cancer du col de l'utérus et de la mortalité associée

Cervical cancer elimination: actions needed in the COVID-19 era

Huang, Junjie ; Wong, Martin C. S.

WHO launched the global Cervical Cancer Elimination Initiative (CCEI) in 2020 to accelerate the elimination of cervical cancer.1 The aim of the initiative is to reduce cervical cancer incidence to less than 4 cases per 100 000 women-years in every country of the world and to narrow disparities between countries. The WHO CCEI also emphasises the need for improved surveillance and continuous monitoring of cervical cancer in all countries. Therefore, it is crucial to monitor risk factors [...]

Menée à partir des données GLOBOCAN portant sur 185 pays et territoires, cette étude présente pour l'année 2020 une estimation de l'incidence du cancer du col de l'utérus et de la mortalité associée

Global estimates of incidence and mortality of cervical cancer in 2020: a baseline analysis of the WHO Global Cervical Cancer Elimination Initiative

Singh, Deependra ; Vignat, Jérôme ; Lorenzoni, Valentina ; Eslahi, Marzieh ; Ginsburg, Ophira ; Lauby-Secretan, Béatrice ; Arbyn, Marc ; Basu, Partha ; Bray, Freddie ; Vaccarella, Salvatore

Background: Tracking progress and providing timely evidence is a fundamental step forward for countries to remain aligned with the targets set by WHO to eliminate cervical cancer as a public health problem (ie, to reduce the incidence of the disease below a threshold of 4 cases per 100 000 women-years). We aimed to assess the extent of global inequalities in cervical cancer incidence and mortality, based on The Global Cancer Observatory (GLOBOCAN) 2020 estimates, including geographical and [...]