Menée en France à partir de questionnaires auprès de 561 patients atteints d'un cancer traité en ambulatoire par chimiothérapie ou radiothérapie, cette étude longitudinale multicentrique identifie les facteurs associés au degré de satisfaction des patients vis-à-vis des soins reçus, puis analyse la relation entre l'évolution de ce degré de satisfaction et leur qualité de vie

A longitudinal analysis of patient satisfaction with care and quality of life in ambulatory oncology based on the OUT-PATSAT35 questionnaire

Nguyen, Thanh ; Anota, Amelie ; Brédart, Anne ; Monnier, Alain ; Bosset, Jean-François ; Mercier, Mariette

Background : In the oncology setting, there has been increasing interest in evaluating treatment outcomes in terms of quality of life and patient satisfaction. The aim of our study was to investigate the determinants of patient satisfaction, especially the relationship between quality of life and satisfaction with care and their changes over time, in curative treatment of cancer outpatients. Methods : Patients undergoing ambulatory chemotherapy or radiotherapy in two centers in France were [...]

Menée par questionnaire auprès de 58 chirurgiens et radiothérapeutes, cette étude internationale analyse et compare les points de vue du patient ou du spécialiste relatifs à la prévalence et à la sévérité des dysfonctionnements intestinaux chez des patients atteints d'un cancer du rectum après leurs traitements

Bowel dysfunction after rectal cancer treatment: a study comparing the specialist's versus patient's perspective

Chen, Tina Yen-Ting ; Emmertsen, Katrine Jøssing ; Laurberg, Søren

Objectives : To investigate how bowel dysfunction after sphincter-preserving rectal cancer treatment, known as low anterior resection syndrome (LARS), is perceived by rectal cancer specialists, in relation to the patient's experience. Design : Questionnaire study.Setting International. Participants : 58 rectal cancer specialists (45 colorectal surgeons and 13 radiation oncologists).Research procedure The Low Anterior Resection Syndrome Score (LARS score) is a five-item instrument for evaluation [...]

Mené sur 277 patients atteints d'un carcinome rénal de stade I ou IV (âge moyen : 58 ans ; 41 % de femmes), cet essai randomisé évalue les benéfices, en termes de qualité de vie, d'une intervention comportant 4 séances d'écriture expressive

Randomized Controlled Trial of Expressive Writing for Patients With Renal Cell Carcinoma

Milbury, Kathrin ; Spelman, Amy ; Wood, Christopher ; Matin, Surena F. ; Tannir, Nizar ; Jonasch, Eric ; Pisters, Louis ; Wei, Qi ; Cohen, Lorenzo

Purpose : This randomized controlled trial examined the quality-of-life benefits of an expressive writing (EW) intervention for patients with renal cell carcinoma (RCC) and identified a potential underlying mechanism of intervention efficacy. Patients and Methods : Patients (N = 277) with stage I to IV RCC were randomly assigned to write about their deepest thoughts and feelings regarding their cancer (EW) or about neutral topics (neutral writing [NW]) on four separate occasions. Patients [...]

Mené sur 200 patientes traitées pour un cancer du sein au cours des trois dernières années et ayant terminé le traitement depuis 2 mois au moins (âge : 27 à 76 ans), cet essai randomisé contrôlé évalue l'intérêt de 2 séances par semaine de Hatha yoga sur une période de 3 mois pour réduire l'inflammation et les symptomes de fatigue post-traitement, et améliorer l'état psychologique des patientes

Yoga’s Impact on Inflammation, Mood, and Fatigue in Breast Cancer Survivors: A Randomized Controlled Trial

Kiecolt-Glaser, Janice K. ; Bennett, Jeanette M. ; Andridge, Rebecca ; Peng, Juan ; Shapiro, Charles L. ; Malarkey, William B. ; Emery, Charles F. ; Layman, Rachel ; Mrozek, Ewa E. ; Glaser, Ronald

Purpose : To evaluate yoga’s impact on inflammation, mood, and fatigue. Patients and Methods : A randomized controlled 3-month trial was conducted with two post-treatment assessments of 200 breast cancer survivors assigned to either 12 weeks of 90-minute twice per week hatha yoga classes or a wait-list control. The main outcome measures were lipopolysaccharide-stimulated production of proinflammatory cytokines interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-  [...]

Menée sur 59 patientes atteintes d'un cancer du sein et ayant subi un traitement conservateur (âge moyen : 50 ans ; durée moyenne de suivi : 34,4 mois), cette étude prospective évalue le risque de récidive et de complications associées à une injection mammaire de graisse autologue

Oncological Safety of Autologous Fat Grafting after Breast Conservative Treatment: A Prospective Evaluation

Brenelli, Fabricio ; Rietjens, Mario ; De Lorenzi, Francesca ; Pinto-Neto, Aarão ; Rossetto, Fabio ; Martella, Stefano ; Rodrigues, José R. P. ; Barbalho, Daniel

Autologous fat graft to the breast is a useful tool to correct defects after breast conservative treatment (BCT). Although this procedure gains popularity, little is known about the interaction between the fat graft and the prior oncological environment. Evidences of safety of this procedure in healthy breast and after post-mastectomy reconstruction exist. However, there is paucity of data among patients who underwent BCT which are hypothetically under a higher risk of local recurrence (LR). [...]

Menée à partir d'entretiens avec 127 patients atteints d'un carcinome épidermoïde de la tête et du cou et à l'aide de questionnaires (âge moyen : 57,9 ans ; 87 % d'hommes), cette étude évalue, en fonction du stade de la maladie, le degré de sévérité de la douleur et son impact sur la qualité de vie des patients avant traitement antinéoplasique

Influence of pain severity on the quality of life in patients with head and neck cancer before antineoplastic therapy

Oliveira, Karine ; von Zeidler, Sandra ; Podesta, Jose ; Sena, Agenor ; Souza, Evandro ; Lenzi, Jeferson ; Bissoli, Nazare ; Gouvea, Sonia

Background : The aim of this study was to assess the severity of pain and its impact on the quality of life (QoL) in untreated patients with head and neck squamous cell carcinoma (HNSCC). Methods : A study group of 127 patients with HNSCC were interviewed before antineoplastic treatment. The severity of pain was measured using the Brief Pain Inventory (BPI) questionnaire, and the QoL was assessed with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [...]

Menée à partir des données de registres de 11 pays, cette étude analyse sur la période 1973-2002 l'évolution de l'incidence du cancer du poumon en fonction du sexe et du sous-type histologique

International trends in lung cancer incidence by histological subtype: adenocarcinoma stabilizing in men but still increasing in women

Lortet-Tieulent, J. ; Soerjomataram, I. ; Ferlay, J. ; Rutherford, M. ; Weiderpass, E. ; Bray, F.

Objectives : Trends in overall lung cancer incidence in different countries reflect the maturity of the smoking epidemic. Further understanding of the underlying causes for trends over time can be gained by assessing the trends by sex and histological subtype. We provide a temporal analysis of lung cancer incidence in 12 populations (11 countries), with a focus on cohort-specific trends for the main histological subtypes (squamous cell carcinomas (SCC), adenocarcinomas (AdC), and small cell [...]

Menée à partir des données 1999-2009 des registres américains des cancers, cette étude analyse, par rapport à la population générale, l'incidence du cancer de la prostate dans une cohorte de188 hommes atteints d'un syndrome de Lynch diagnostiqué entre 1998 et 2012

Prostate cancer incidence in males with Lynch syndrome

Haraldsdottir, Sigurdis ; Hampel, Heather ; Wei, Lai ; Wu, Christina ; Frankel, Wendy ; Bekaii-Saab, Tanios ; de la Chapelle, Albert ; Goldberg, Richard M.

Purpose : An increased risk of prostate cancer is currently not considered a part of the Lynch syndrome spectrum. The purpose of this study was to retrospectively examine prostate cancer incidence in the Lynch syndrome cohort at the Ohio State University in comparison with that in the general population. Methods : We included all males diagnosed with Lynch syndrome from June 1998 to June 2012 at the Ohio State University and obtained baseline information including cancer history. If patients [...]

Menée à partir des données 2001-2007 de registres anglais portant sur 11 263 patients atteints d'un cancer de la thyroïde, cette étude analyse le taux d'incidence de la maladie par groupe ethnique

Incidence of thyroid cancer in England by ethnic group, 2001-2007

Finlayson, A. ; Barnes, I. ; Sayeed, S. ; McIver, B. ; Beral, V. ; Ali, R.

Background : Thyroid cancer incidence is increasing worldwide, but with large variations in incidence that may reflect either diagnostic bias or true ethnic differences. We sought to determine the effect of ethnicity on the incidence of thyroid cancer in England, a multiethnic population with a single health-care system. Methods : We analysed 11 263 thyroid cancer registrations with ethnicity obtained by linkage to the Hospital Episodes Statistics database. Incidence rate ratios (RRs) adjusted [...]

Menée à partir des données d'un essai portant sur 113 patients atteints d'un cancer, cette étude évalue l'efficacité d'un traitement comportemental et cognitif de l'insomnie pour réduire le niveau de fatigue, d'anxiété et de dépression des patients

Does cognitive behaviour therapy for insomnia reduce clinical levels of fatigue, anxiety and depression in cancer patients?

Fleming, Leanne ; Randell, Kate ; Harvey, Christopher-James ; Espie, Colin A.

Objectives : This secondary analysis of data from a randomised controlled trial explores associations between common symptom clusters and evaluates pre-treatment to post-treatment changes in clinical levels of these symptoms following cognitive behaviour therapy for insomnia (CBT-I). Methods : Baseline data from 113 participants with insomnia were explored to establish rates of and associations between clinical levels of fatigue, anxiety and depression across the sample. Effects of CBT-I on [...]

Menée sur 582 patients atteints d'un cancer, cette étude évalue, par rapport aux pratiques usuelles, l'intérêt d'utiliser un outil d'auto-évaluation pour détecter de manière systématique et efficace le niveau de détresse psychologique des patients avant une consultation oncologique

Systematic screening for distress in oncology practice using the Distress Barometer: the impact on referrals to psychosocial care

Bauwens, Sabien ; Baillon, Catherine ; Distelmans, Willem ; Theuns, Peter

Purpose : This study evaluates how patterns of psychosocial referral of patients with elevated distress differ in a ‘systematic screening for distress’ condition versus a ‘usual practice’ condition in ambulatory oncology practice. Methods : The psychosocial referral process in a 2-week usual practice (N = 278) condition was compared with a 2-week ‘using the Distress Barometer as a screening instrument’ (N=304) condition in an outpatient clinic with seven consulting oncologists. Results : Out of [...]

A partir d'une revue systématique de la littérature publiée entre1966 et 2011, cette étude analyse le rapport coût-efficacité de différentes stratégies de prise en charge du cancer de la vessie

The Economics of Bladder Cancer: Costs and Considerations of Caring for This Disease

Robert S. Svatek ; Brent K. Hollenbeck ; Sten Holmäng ; Richard Lee ; Simon Kim ; Arnulf Stenzl ; Yair Lotan

Context : Due to high recurrence rates, intensive surveillance strategies, and expensive treatment costs, the management of bladder cancer contributes significantly to medical costs. Objective : To provide a concise evaluation of contemporary cost-related challenges in the care of patients with bladder cancer. An emphasis is placed on the initial diagnosis of bladder cancer and therapy considerations for both non–muscle-invasive bladder cancer (NMIBC) and more advanced disease. Evidence [...]

Mené auprès de 481 participants domiciliés dans des zones géographiques mal desservies et dont un parent est atteint d'un cancer colorectal (âge : 30 à 74 ans), cet essai américain compare l'efficacité de deux interventions pour inciter les participants à subir une coloscopie : l'une basée sur des entretiens téléphoniques permettant d'évaluer le risque de cancer colorectal et d'informer sur la coloscopie, l'autre reposant uniquement sur l'envoi d'une brochure pédagogique

Telehealth Personalized Cancer Risk Communication to Motivate Colonoscopy in Relatives of Patients With Colorectal Cancer: The Family CARE Randomized Controlled Trial

Kinney, Anita Y. ; Boonyasiriwat, Watcharaporn ; Walters, Scott T. ; Pappas, Lisa M. ; Stroup, Antoinette M. ; Schwartz, Marc D. ; Edwards, Sandra L. ; Rogers, Amy ; Kohlmann, Wendy K. ; Boucher, Kenneth M. ; Vernon, Sally W. ; Simmons, Rebecca G. ; Lowery, Jan T. ; Flores, Kristina ; Wiggins, Charles L. ; Hill, Deirdre A. ; Burt, Randall W. ; Williams, Marc S. ; Higginbotham, John C.

Purpose : The rate of adherence to regular colonoscopy screening in individuals at increased familial risk of colorectal cancer (CRC) is suboptimal, especially among rural and other geographically underserved populations. Remote interventions may overcome geographic and system-level barriers. We compared the efficacy of a telehealth-based personalized risk assessment and communication intervention with a mailed educational brochure for improving colonoscopy screening among at-risk relatives of [...]

Menée à partir d'une enquête auprès de 1 490 oncologues américains (âge médian : 52 ans), cette étude évalue leur degré de satisfaction vis-à-vis de leur carrière professionnelle et le taux d'épuisement professionnel

Burnout and Career Satisfaction Among US Oncologists

Shanafelt, Tait D. ; Gradishar, William J. ; Kosty, Michael ; Satele, Daniel ; Chew, Helen ; Horn, Leora ; Clark, Ben ; Hanley, Amy E. ; Chu, Quyen ; Pippen, John ; Sloan, Jeff ; Raymond, Marilyn

Purpose : To evaluate the personal and professional characteristics associated with career satisfaction and burnout among US oncologists. Methods : Between October 2012 and March 2013, the American Society of Clinical Oncology conducted a survey of US oncologists evaluating burnout and career satisfaction. The survey sample included equal numbers of men and women and represented all career stages. Results : Of 2,998 oncologists contacted, 1,490 (49.7%) returned surveys (median age of [...]