A partir d'une revue de la littérature publiée de 2001 à 2011 (21 études incluant 4 067 patients), cette étude livre une synthèse sur la prévalence et la sévérité des symptômes associés à la maladie et aux traitements chez des patients atteints de cancer

A literature synthesis of symptom prevalence and severity in persons receiving active cancer treatment

Reilly, CarolynMiller ; Bruner, DeborahWatkins ; Mitchell, SandraA ; Minasian, LoriM ; Basch, Ethan ; Dueck, AmylouC ; Cella, David ; Reeve, BryceB

Purpose : Patients with cancer experience acute and chronic symptoms caused by their underlying disease or by the treatment. While numerous studies have examined the impact of various treatments on symptoms experienced by cancer patients, there are inconsistencies regarding the symptoms measured and reported in treatment trials. This article presents a systematic review of the research literature of the prevalence and severity of symptoms in patients undergoing cancer treatment. Methods : A [...]

Cette étude fait un point sur l'étiologie, la définition, l'évaluation, la prise en charge de la fatigue liée au cancer, analyse les différences européenne et américaine en matière de recherches sur ce sujet et évalue l'impact de la fatigue sur les capacités physiques des survivants d'un cancer

Cancer-related fatigue and its impact on functioning

Minton, Ollie ; Berger, Ann ; Barsevick, Andrea ; Cramp, Fiona ; Goedendorp, Martine ; Mitchell, Sandra A. ; Stone, Patrick C.

This article presents the contrasting European and American perspectives on cancer-related fatigue (CRF) and its impact on functioning in cancer survivors. The content is presented in 3 sections: state of the art, intervention studies, and future areas of research, followed by a discussion. Gaps identified include a lack of understanding of the etiology, definition, and measurement of CRF. Models to guide the study of CRF, selection of biomarkers, and design of interventions are needed. There [...]

A partir des données de la cohorte "NHANES" incluant 126 survivants adultes d'un cancer, cette étude américaine évalue l'association entre le poids de l'individu et son niveau d'activité physique mesuré de façon objective

Objectively measured physical activity among US cancer survivors: considerations by weight status

Loprinzi, PaulD ; Lee, Hyo ; Cardinal, BradleyJ

Purpose : We have a limited understanding of the objectively determined physical activity levels of cancer survivors at the population level. Further, we have even less of an understanding of this behavior by weight status (i.e., normal weight, overweight, and obese). Therefore, the purpose of this study was to describe accelerometer-assessed physical activity levels among US cancer survivors and to do so across weight status. Methods : Data from the 2003–2006 NHANES was used. One hundred [...]

Cette étude fait le point sur les problématiques associées au diagnostic, au traitement et à la prise en charge des maladies cardiaques chez les survivants d'un cancer, en Europe et aux Etats-Unis

Cardiac toxicity in cancer survivors

Lenihan, Daniel J. ; Oliva, Stefano ; Chow, Eric J. ; Cardinale, Daniela

Cardiac disease is a major concern for cancer survivors, and this can be manifested as cardiac dysfunction from myocardial damage, valvular disease, atherosclerosis, and/or pericardial disease. In this “dialogue” between select European and American investigators, present current perspectives (both similarities and differences) are presented regarding the diagnosis and management of cardiac disease among cancer survivors, with a focus on left ventricular (LV) systolic dysfunction and heart [...]

Menée au Royaume-Uni auprès de 540 participants, cette étude analyse, au moment du diagnostic, les expériences et les besoins des patients atteints d'un cancer thoracique en matière d'ergothérapie

Occupational therapy needs of patients with thoracic cancer at the time of diagnosis: findings of a dedicated rehabilitation service

Bentley, Rachel ; Hussain, Asmah ; Maddocks, Matthew ; Wilcock, Andrew

Purpose : Guidelines recommend screening patients with cancer to identify their rehabilitation needs. To help quantify this area of need and associated workload from an occupational therapy perspective in patients with thoracic cancer, we report the experiences of a dedicated rehabilitation service. Methods : Consecutive patients were screened soon after diagnosis using items associated with occupational performance in the Sheffield Profile for Assessment and Referral for Care questionnaire. [...]

Menée par enquête auprès de 82 patients, cette étude multicentrique canadienne analyse les besoins des patients pendant la phase du pré-diagnostic de cancer colorectal, que ce soit en terme d'information ou de soutien psychologique

Understanding the Needs of Colorectal Cancer Patients during the Pre-diagnosis Phase

Wiljer, David ; Walton, Tara ; Gilbert, Julie ; Boucher, Amy ; Ellis, PeterM ; Schiff, Susan ; Sellick, ScottM ; Simunovic, Marko ; Kennedy, Erin ; Urowitz, Sara

Patients with colorectal cancer (CRC) face a number of challenges leading up to diagnosis; however, research is limited regarding their specific needs during the pre-diagnosis period. A multicenter cross-sectional survey was conducted to elicit information about the CRC experience during the pre-diagnosis phase. Across the three sites, 104 eligible patients were approached, and 82 patients completed the survey, for a total response rate of 78.9 %. The needs most identified by participants [...]

Menée auprès de 1 062 patients atteints d'un lymphome des voies gastrointestinales diagnostiqué entre 1975 et 2012, cette étude américaine analyse la fréquence des perforations intestinales, au diagnostic ou après une chimiothérapie

Bowel perforation in intestinal lymphoma: incidence and clinical features

Vaidya, R. ; Habermann, T. M. ; Donohue, J. H. ; Ristow, K. M. ; Maurer, M. J. ; Macon, W. R. ; Colgan, J. P. ; Inwards, D. J. ; Ansell, S. M. ; Porrata, L. F. ; Micallef, I. N. ; Johnston, P. B. ; Markovic, S. N. ; Thompson, C. A. ; Nowakowski, G. S. ; Witzig, T. E.

Background : Perforation is a serious life-threatening complication of lymphomas involving the gastrointestinal (GI) tract. Although some perforations occur as the initial presentation of GI lymphoma, others occur after initiation of chemotherapy. To define the location and timing of perforation, a single-center study was carried out of all patients with GI lymphoma. Patients and methods : Between 1975 and 2012, 1062 patients were identified with biopsy-proven GI involvement with lymphoma. A [...]

A partir des données d'un registre américain des cancers et d'une cohorte observationnelle incluant 3 141 patients infectés par le VIH, cette étude analyse l'évolution, sur la période 2000-2011, de l'incidence des cancers par localisation

Recent cancer incidence trends in an observational clinical cohort of HIV-infected patients in the US, 2000 to 2011

Yanik, Elizabeth ; Tamburro, Kristen ; Eron, Joseph ; Damania, Blossom ; Napravnik, Sonia ; Dittmer, Dirk

BACKGROUND:In HIV-infected population in developed countries, the most recent published cancer incidence trend analyses are only updated through 2008. We assessed changes in the distribution of cancer types and incidence trends among HIV-infected patients in North Carolina up until 2011. METHODS:We linked the University of North Carolina Center for AIDS Research HIV Clinical Cohort, an observational clinical cohort of 3141 HIV-infected patients, with the North Carolina Cancer registry. Cancer [...]

A partir des données des registres norvégien, suédois et danois des cancers portant sur 29 628 patients atteints de cancer colorectal métastatique synchrone, cette étude analyse l'évolution de la survie médiane et à long terme sur la période 1980-2008

Age-dependent improvement in median and long-term survival in unselected population-based Nordic registries of patients with synchronous metastatic colorectal cancer

Sorbye, H. ; Cvancarova, M. ; Qvortrup, C. ; Pfeiffer, P. ; Glimelius, B.

Background : In metastatic colorectal cancer (mCRC) trials, median survival has increased from 6 months to above 20 months during the previous decades. Uncertainty exists in how this survival improvement has translated to the general mCRC population. Patients and methods : Survival data from patients with synchronous mCRC were collected from the Norwegian (1980–2008), Swedish (1996–2008) and Danish (2001–09) cancer registries. Results : A total of 29 628 patients were identified. From 1980–1985 [...]

A partir d'une revue systématique de la littérature (34 études) cette étude analyse les écarts entre les recommandations de suivi d'un cancer colorectal et la manière dont les procédures recommandées sont appliquées

Receipt of recommended surveillance among colorectal cancer survivors: a systematic review

Carpentier, MelissaY ; Vernon, SallyW ; Bartholomew, L. Kay ; Murphy, CaitlinC ; Bluethmann, ShirleyM

Purpose : Regular surveillance decreases the risk of recurrent cancer in colorectal cancer (CRC) survivors. However, studies suggest that receipt of follow-up tests is not consistent with guidelines. This systematic review aimed to: (1) examine receipt of recommended post-treatment surveillance tests and procedures among CRC survivors, including adherence to established guidelines, and (2) identify correlates of CRC surveillance. Methods : Systematic searches of Medline, PubMed, PsycINFO, [...]

A partir des données d'un registre néerlandais des cancers portant sur 3 080 survivants, cette étude prospective en population évalue l'association entre des symptômes dépressifs et la mortalité, toutes causes confondues

Depressive symptoms are a risk factor for all-cause mortality: results from a prospective population-based study among 3,080 cancer survivors from the PROFILES registry

Mols, Floortje ; Husson, Olga ; Roukema, Jan-Anne ; Poll-Franse, LonnekeV

Background : The goal of this large prospective population-based study was to examine the association between depressive symptoms and all-cause mortality among cancer survivors up to 10 years post-diagnosis. Methods : All currently alive individuals diagnosed with endometrial or colorectal cancer (CRC) between 1998 and 2007 or with lymphoma or multiple myeloma between 1999 and 2008, as registered in the Eindhoven Cancer Registry, received a questionnaire on depressive symptoms (Hospital Anxiety [...]

Menée en Chine par enquête auprès de dyades patients-soignants, cette étude analyse la prévalence de la dépression chez des patients atteints d'un cancer de l'œsophage ainsi que chez leurs aidants familiaux

Determinants of hopelessness and depression among Chinese hospitalized esophageal cancer patients and their family caregivers

Han, Yanhong ; Yuan, Jie ; Luo, Zhiguo ; Zhao, Jing ; Wu, Junbo ; Liu, Rongying ; Lopez, Violeta

Background : It has been well documented that the diagnosis of cancer is psychologically devastating to both the patients and caregivers. The incidence and mortality of esophageal cancer were 20.85 and 16.24 per 100,000 persons and the sixth most commonly diagnosed cancer and the fourth main cause of cancer death in China. We surveyed patients–caregivers dyad and examined the determinants of their depression and hopelessness. Results : The prevalence of depression among patients and caregivers [...]

Menée par questionnaire auprès de 222 soignants, cette étude analyse leurs opinions relatives aux options thérapeutiques des cancers pédiatriques en Indonésie, en fonction des difficultés financières des parents et de leur adhésion vis-à-vis des protocoles thérapeutiques

Health-care providers' perspectives on childhood cancer treatment in Manado, Indonesia

Mostert, S. ; Gunawan, S. ; van Dongen, J. A. P. ; van de Ven, P. M. ; Sitaresmi, M. N. ; Wolters, E. E. ; Veerman, A. J. P. ; Mantik, M. ; Kaspers, G. J. L.

Background Childhood cancer survival in low-income countries is low. Objective : Our study investigated health-care providers' perspectives on childhood cancer treatment in Indonesia. Their health beliefs and attitudes toward parental financial difficulties, protocol adherence, parental education, and communication were explored. Methods A self-administered questionnaire was filled in by 222 health-care providers (156 doctors, 51 nurses, 6 social workers, 9 administrators) Results : Health of [...]

Menée au Royaume-Uni dans un centre de lutte contre le cancer auprès de 16 patients et de 16 médecins, cette étude analyse leurs expériences relatives à la communication et à l'annonce de mauvaises nouvelles lors de consultations d'oncologie

Investigating communication in cancer consultations: what can be learned from doctor and patient accounts of their experience?

Furber, L. ; Cox, K. ; Murphy, R. ; Steward, W.

This study investigated how doctors and patients diagnosed with advanced incurable cancer experienced the disclosure of bad news. The intention was to gain contrasting perspectives of the processes involved in oncology consultations. Sixteen doctors and 16 patients from a cancer centre in the UK participated in the study. A series of consultations were observed and audio recorded, and the perspectives of doctors, patients and relatives were investigated through semi-structured interviews. [...]

Cette étude internationale présente un consensus d'experts relatif à l'identification des phénomènes témoignant des derniers moments de la vie du patient atteint de cancer

International palliative care experts’ view on phenomena indicating the last hours and days of life

Domeisen Benedetti, Franzisca ; Ostgathe, Christoph ; Clark, Jean ; Costantini, Massimo ; Daud, MariaLaura ; Grossenbacher-Gschwend, Barbara ; Latten, Richard ; Lindqvist, Olav ; Peternelj, Andreja ; Schuler, Stefanie ; Tal, Kali ; Heide, Agnes ; Eychmüller, Steffen

Background : Providing the highest quality care for dying patients should be a core clinical proficiency and an integral part of comprehensive management, as fundamental as diagnosis and treatment. The aim of this study was to provide expert consensus on phenomena for identification and prediction of the last hours or days of a patient’s life. This study is part of the OPCARE9 project, funded by the European Commission’s Seventh Framework Programme. Method : The phenomena associated with [...]