Cette étude menée auprès de 16 cas et 11 témoins analyse et compare les fonctions cardio-respiratoires et neuro-musculaires chez des survivantes d'un cancer du sein ayant terminé leur traitement et présentant, ou non, des symptômes de fatigue

Cardiorespiratory and neuromuscular deconditioning in fatigued and non-fatigued breast cancer survivors

Neil, SarahE ; Klika, RiggsJ ; Garland, S. Jayne ; McKenzie, DonaldC ; Campbell, KristinL

Purpose : Fatigue is one of the most commonly reported side effects during treatment for breast cancer and can persist following treatment completion. Cancer-related fatigue after treatment is multifactorial in nature, and one hypothesized mechanism is cardiorespiratory and neuromuscular deconditioning. The purpose of this study was to compare cardiorespiratory and neuromuscular function in breast cancer survivors who had completed treatment and met the specified criteria for cancer-related [...]

Menée en Serbie par questionnaire auprès de 202 survivants à long terme d'un cancer du testicule, cette étude transversale analyse leur qualité de vie, leur dépression et leurs dsyfonctionnements sexuels

Health-related quality of life, depression, and sexual function in testicular cancer survivors in a developing country: a Serbian experience

Bumbasirevic, Uros ; Bojanic, Nebojsa ; Pekmezovic, Tatjana ; Janjic, Aleksandar ; Janicic, Aleksandar ; Milojevic, Bogomir ; Tulic, Cane

Purpose : The aims of this study were to assess health-related quality of life (HRQoL), depression, adverse physical symptoms, and sexual function within Serbian long-term testicular cancer survivors (TCS) and to address cultural specificity. Methods : This is a cross-sectional study involving 202 TCS, followed up after platinum-based chemotherapy. The HRQoL was measured using the Short Form 36 and the European Organization for Research and Treatment of Cancer Quality of Life questionnaire. The [...]

A partir des données de l'Organisation Mondiale de la Santé, cette étude analyse et compare l'évolution de la mortalité par cancer primitif du foie et par cholangiocarcinome intra-hépatique en Europe sur la période 1990-2010

A comparison of trends in mortality from primary liver cancer and intrahepatic cholangiocarcinoma in Europe

Bertuccio, P. ; Bosetti, C. ; Levi, F. ; Decarli, A. ; Negri, E. ; La Vecchia, C.

Background : To update and compare mortality from primary liver cancer (PLC) and intrahepatic cholangiocarcinoma (ICC) in Europe in 1990–2010. Materials and methods : We used data from the World Health Organization (WHO) to compute age-standardized (world population) mortality rates, and used joinpoint analysis to identify substantial changes. Results : Between 2002 and 2007, PLC rates in the European Union (EU) declined from 3.9 to 3.6/100 000 men. Around 2007, the highest male rates were in [...]

A partir des données du registre suédois des cancers, cette étude analyse et compare la survie des patients atteints d'un cancer métastatique en fonction de son origine, connue ou inconnue

Comparison of survival of patients with metastases from known versus unknown primaries: survival in metastatic cancer

Riihimäki, Matias ; Thomsen, Hauke ; Hemminki, Akseli ; Sundquist, Kristina ; Hemminki, Kari

BACKGROUND:Cancer of unknown primary site (CUP) is considered an aggressive metastatic disease but whether the prognosis differs from metastatic cancers of known primary site is not known. Such data may give insight into the biology of CUP and the metastatic process in general. METHODS:6,745 cancer patients, with primary metastatic cancer at diagnosis, were identified from the Swedish Cancer Registry, and were compared with 2,881 patients with CUP. Patients were diagnosed and died between 2002 [...]

A partir des données des registres américains des cancers, cette étude analyse l'évolution de l'incidence nationale du mésothéliome sur la période 2003-2008

Mesothelioma incidence in 50 states and the District of Columbia, United States, 2003–2008

S. Jane Henley ; Theodore C. Larson ; Manxia Wu ; Vinicius C. S. Antao ; Mary Lewis ; Germania A. Pinheiro ; Christie Eheman

Background: The decline in asbestos use in the United States may impact mesothelioma incidence. Objective: This report provides national and state-specific estimates of mesothelioma incidence in the United States using cancer surveillance data for the entire US population. Methods: Data from the National Program for Cancer Registries and the Surveillance, Epidemiology, and End Results program were used to calculate incidence rates and annual percent change. Results: During 2003–2008, an average [...]

Menée auprès de 687 patientes atteintes d'un cancer du sein, cette étude de cohorte évalue l'association entre le temps passé à regarder la télévision et les causes de mortalité

The association between television watching time and all-cause mortality after breast cancer

George, StephanieM ; Smith, AshleyW ; Alfano, CatherineM ; Bowles, HeatherR ; Irwin, MelindaL ; McTiernan, Anne ; Bernstein, Leslie ; Baumgartner, KathyB ; Ballard-Barbash, Rachel

Purpose : Sedentary time is a rapidly emerging independent risk factor for mortality in the general population, but its prognostic effect among cancer survivors is unknown. In a multiethnic, prospective cohort of breast cancer survivors, we hypothesized that television watching time would be independently associated with an increased risk of death from any cause. Methods: The Health, Eating, Activity, and Lifestyle Study cohort included 687 women diagnosed with local or regional breast cancer. [...]

Menée auprès de 2 325 patientes atteintes d'un cancer du sein, cette étude de cohorte américaine analyse et compare, chez les femmes blanches hispaniques et non hispaniques, les caractéristiques cliniques (taille, indice de masse corporelle) associées au statut de la tumeur

Differences between Hispanic and non-Hispanic white women with breast cancer for clinical characteristics and their correlates

Connor, Avonne E. ; Baumgartner, Richard N. ; Yang, Dongyan ; Slattery, Martha L. ; Giuliano, Anna R. ; Risendal, Betsy C. ; Abdel-Maksoud, Madiha M. ; Baumgartner, Kathy B.

Body size and ethnicity may influence breast cancer tumor characteristics at diagnosis. We compared Hispanic and non-Hispanic white (NHW) cases for stage of disease, estrogen receptor (ER) status, tumor size, and lymph node status, and the associations of these with body size in the 4-Corners Breast Cancer Study. One thousand five hundred twenty-seven NHW and 798 Hispanic primary incident breast cancer cases diagnosed between October 1999 and May 2004 were included. Odds ratios (ORs) and 95% [...]

Menée au Brésil auprès de 253 patients atteints de cancer et soignés par chimiothérapie, cette étude analyse l'efficacité de sessions de groupes de thérapies par l'art pour améliorer leur bien-être

Infusion of Life: patient perceptions of expressive therapy during chemotherapy sessions

Vianna, D. ; Claro, L. L. ; Mendes, A. A. ; da Silva, A. N. ; Bucci, D. A. ; de Sá, P. T. ; Rocha, V. S. ; Pincer, J. S. ; de Barros, I. M. F. ; Silva, P. R.

Through a quanti-qualitative study, we observed the effects of group expressive therapy (ET) sessions on patients’ feelings and sense of well-being, as part of the Infusion of Life project. This project is part of a broader programme to improve integral care, developed by an interdisciplinary team headed by a medical doctor who is also an artist and expert in ET. We offered 48 group ET sessions to a total of 253 outpatients with cancer or autoimmune disorders receiving venous infusions in the [...]

Menée auprès de 530 patients atteints de cancer et âgés de moins de 65 ans, cette étude de cohorte américaine analyse les conditions de retour au travail de survivants d'un cancer

Employment outcomes among survivors of common cancers: the Symptom Outcomes and Practice Patterns (SOAPP) study

Tevaarwerk, A. J. ; Lee, J. W. ; Sesto, M. E. ; Buhr, K. A. ; Cleeland, C. S. ; Manola, J. ; Wagner, L. I. ; Chang, V. T. S. ; Fisch, M. J.

Introduction : Risk factors for employment difficulties after cancer diagnosis are incompletely understood, and interventions to improve post-cancer employment remain few. New targets for intervention are needed. Methods : We assessed a cohort of 530 nonmetastatic cancer patients (aged ≤65 years, >6 months from diagnosis, off chemo- or radiotherapy) from the observational multi-site Symptom Outcomes and Practice Patterns study. Participants reported employment change, current employment, and [...]

Mené auprès de 309 mères de langue anglaise ou espagnole, cet essai américain analyse l'efficacité d'une intervention destinée à les aider psychologiquement en réduisant leurs symptômes d'anxiété et de stress après un diagnostic de cancer chez leur enfant

Specificity of Problem-Solving Skills Training in Mothers of Children Newly Diagnosed With Cancer: Results of a Multisite Randomized Clinical Trial

Sahler, Olle Jane Z. ; Dolgin, Michael J. ; Phipps, Sean ; Fairclough, Diane L. ; Askins, Martha A. ; Katz, Ernest R. ; Noll, Robert B. ; Butler, Robert W.

Purpose : Diagnosis of cancer in a child can be extremely stressful for parents. Bright IDEAS, a problem-solving skills training (PSST) intervention, has been shown to decrease negative affectivity (anxiety, depression, post-traumatic stress symptoms) in mothers of newly diagnosed patients. This study was designed to determine the specificity of PSST by examining its direct and indirect (eg, social support) effects compared with a nondirective support (NDS) intervention. Patients And methods : [...]

Menée en France auprès de 4 270 survivants de cancer, cette étude transversale analyse les conditions de reprise du travail pour les survivants d'un cancer, deux ans après le diagostic, en comparant les situations pour les hommes et pour les femmes

Sex Differences in the Return-to-Work Process of Cancer Survivors 2 Years After Diagnosis: Results From a Large French Population-Based Sample

Marino, Patricia ; Teyssier, Luis Sagaon ; Malavolti, Laetitia ; Le Corroller-Soriano, Anne-Gaelle

Purpose : To investigate the effects of clinical, sociodemographic, and occupational factors on time to return to work (RTW) during the 2 years after cancer diagnosis and to analyze whether sex differences exist. Patients and Methods : This study was based on a French national cross-sectional survey involving 4,270 cancer survivors. Time to RTW was estimated through the duration of sick leave of 801 cancer survivors younger than 58 years who were employed during the 2-year survey. Multivariate [...]

Menée en Grèce, cette étude transversale analyse les symptômes de détresse psychologique, les traits de la personnalité et la qualité de vie de patients atteints de cancer d'origine primitve inconnue

Psychiatric manifestations, personality traits and health-related quality of life in cancer of unknown primary site

Hyphantis, Thomas ; Papadimitriou, Ilias ; Petrakis, Dimitrios ; Fountzilas, George ; Repana, Dimitra ; Assimakopoulos, Konstantinos ; Carvalho, André F. ; Pavlidis, Nicholas

Objective Psychiatric manifestations and personality traits are known to influence cancer patients. We aimed to assess psychological distress symptoms, psychosocial factors and health-related quality of life (HRQoL) in cancer of unknown primary site (CUP) and to test whether these parameters differ between CUP and Metastatic (MKPC) or Non-Metastatic Known Primary Cancers (N-MKPC) after controlling for demographics and clinical variables. Methods In this cross-sectional study, we recruited 50 [...]

A partir d'une revue systématique de la littérature (14 études), cette étude fait le point sur l'impact du volume hospitalier d'actes d'oncologie pédiatrique sur la qualité des soins et sur la survie des enfants atteints de cancer

The volume effect in paediatric oncology: a systematic review

Knops, R. R. G. ; van Dalen, E. C. ; Mulder, R. L. ; Leclercq, E. ; Knijnenburg, S. L. ; Kaspers, G. J. L. ; Pieters, R. ; Caron, H. N. ; Kremer, L. C. M.

Background : For several adult cancer types, there is evidence that treatment in high volume hospitals, high case volume providers, or in specialised hospitals leads to a better outcome. The aim of this study is to give an overview of the existing evidence regarding the volume effect in paediatric oncology related to the quality of care or survival. Materials and methods : An extensive search was carried out for studies on the effect of provider case volume on the quality of care or survival in [...]

A partir de données portant sur 198 patients nord-irlandais en 2005, cette étude analyse les coûts associés aux soins dispensés aux patients atteints d'un cancer de l'œsophage durant l'année suivant le diagnostic

Description and predictors of hospital costs of oesophageal cancer during the first year following diagnosis in Northern Ireland

Agus, A. M. ; Kinnear, H. ; O'Neill, C. ; McDowell, C. ; Crealey, G. E. ; Gavin, A.

The cost-effectiveness of novel interventions in the treatment of cancer is well researched; however, relatively little attention is paid to the cost of many aspects of routine care. Oesophageal cancer is the ninth most common cancer in the UK and sixth most common cause of cancer death. It usually presents late and has a poor prognosis. The hospital costs incurred by oesophageal cancer patients diagnosed in Northern Ireland in 2005 (n = 198) were determined by review of medical records. The [...]

Menée par entretiens téléphoniques auprès de 19 079 participants âgés de 50 ans, cette étude analyse les différences relatives aux connaissances et croyances sur le cancer entre des personnes vivant en Australie, au Canada, en Norvège, en Suède et au Royaume-Uni, puis évalue dans quelle mesure ces connaissances contribuent aux disparités de survie

Differences in cancer awareness and beliefs between Australia, Canada, Denmark, Norway, Sweden and the UK (the International Cancer Benchmarking Partnership): do they contribute to differences in cancer survival ?

Forbes, L. J. L. ; Simon, A. E. ; Warburton, F. ; Boniface, D. ; Brain, K. E. ; Dessaix, A. ; Donnelly, C. ; Haynes, K. ; Hvidberg, L. ; Lagerlund, M. ; Lockwood, G. ; Tishelman, C. ; Vedsted, P. ; Vigmostad, M. N. ; Ramirez, A. J. ; Wardle, J.

Background: There are wide international differences in 1-year cancer survival. The UK and Denmark perform poorly compared with other high-income countries with similar health care systems: Australia, Canada and Sweden have good cancer survival rates, Norway intermediate survival rates. The objective of this study was to examine the pattern of differences in cancer awareness and beliefs across these countries to identify where these might contribute to the pattern of survival. Methods: We [...]

A partir des données du registre finlandais des cancers portant sur 23 types de cancer entre 1954 et 2003, cette étude évalue diverses méthodes d'analyse des données de survie

Study populations for period analyses of cancer survival

Jansen, L. ; Hakulinen, T. ; Brenner, H.

Background: Period analysis is increasingly used to compute long-term cancer survival, as it provides better prediction of survival of newly diagnosed patients than traditional cohort analysis. However, the patient population to which period survival estimates best pertain to and which should be described in a study is less obvious. Methods:Using Finnish Cancer Registry data on 23 common cancer sites, age-standardized period estimates of 5-, 10-, 15-, and 20-year relative survival were computed [...]

Menée par entretiens auprès de 2 524 participantes, cette étude évalue, aux Etats-Unis, les pratiques de recours à des tests génétiques chez les femmes à risque aggravé de cancer de l'ovaire lié à une histoire familiale

Prevalence and healthcare actions of women in a large health system with a family history meeting the 2005 USPSTF recommendation for BRCA genetic counseling referral

Bellcross, Cecelia A ; Leadbetter, Steven D. ; Hensley Alford, Sharon ; Peipins, Lucy A

Methods: As part of a study evaluating ovarian cancer risk perception and screening, 2,524 randomly-selected participants completed a detailed interview (response rate 76%) from an initial eligible cohort of 16,720 women. Results: Approximately 6% of participants had a family history fulfilling one or more of the USPSTF patterns. Although 90% of these women had shared their family history with their provider, fewer than 20% had been referred for genetic counseling and only 8% had undergone [...]