Traffic-related air pollution and risk of lung, breast and urinary tract cancer in Halifax, Nova Scotia

Menée en Nouvelle-Ecosse auprès de 8 501 témoins et 2 315 patients atteints d'un cancer (poumon, sein ou voies urinaires), cette étude analyse l'association entre une exposition à la pollution atmosphérique liée à la circulation et le risque de développer la maladie

Résumé en anglais

Objectives: We assessed the association of traffic-related air pollution (TRAP) with the incidence of lung, breast and urinary tract cancer in Halifax, Nova Scotia.

Methods: Our case-control study included 2315 cancers and 8501 age-sex matched controls. Land-use regression was used to estimated TRAP concentrations. Logistic regression was used to assess cancer risk in relation to TRAP, adjusting for community social and material deprivation.

Results: There was no association between the risk of lung, breast or urinary tract cancer in relation to TRAP. Lung cancer risk was significantly increased in the most deprived communities, whereas breast cancer risk was highest in the least deprived communities.

Conclusions: In a city characterized by low levels of ambient air pollution, there was no evidence of a linear increased lung, breast or urinary tract cancer risk in relation to TRAP.