Mené en Iran sur 150 patientes atteintes d'un cancer du sein, cet essai randomisé évalue l'efficacité d'une intervention à base de conseils alimentaires dispensés pendant une chimiothérapie adjuvante, pour réduire la sévérité des nausées et vomissements induits par la chimiothérapie et améliorer la qualité de vie

Randomized Study of the Effect of Dietary Counseling During Adjuvant Chemotherapy on Chemotherapy Induced Nausea and Vomiting, and Quality of Life in Patients With Breast Cancer

Najafi, Safa ; Haghighat, Shahpar ; Raji Lahiji, Mahsa ; RazmPoosh, Elham ; Chamari, Maryam ; Abdollahi, Reyhaneh ; Asgari, Marziyeh ; Zarrati, Mitra

Patients with breast cancer (PsBC) usually face with chemotherapy induced nausea and vomiting (CINV). The aim of this study was to assess the impact of nutritional counseling on CINV and quality of life (QoL) of PsBC. 150 PsBC were randomly assigned for receiving a personalized diet, which contained 1.2?1.5?g/kg of protein, 30% of energy from fat and 55?60% of energy from carbohydrate, a face to face nutrition education, and a pamphlet which contained beneficial nutrition information to reduce [...]

Menée en Suède par entretiens auprès de 135 patients ayant survécu à un cancer de la tête et du cou, cette étude analyse leurs expériences et leurs difficultés pour s'alimenter et boire, durant les deux années après la fin des traitements

Experiences and coping strategies related to food and eating up to two years after the termination of treatment in patients with head and neck cancer

Einarsson, Sandra ; Laurell, Göran ; Tiblom Ehrsson, Ylva

The purpose was to describe how patients with head and neck cancer experience and cope with difficulties related to food and eating up to two years after the termination of treatment. One hundred and thirty-five patients were followed with thematically structured interviews. The patients’ responses of nutritional issues were categorised using similarities and differences technique. In the analysis, six categories emerged describing the process of eating and drinking from the end of treatment up [...]

Mené en Chine sur 128 patients atteints d'un cancer de la tête et du cou traité par radiothérapie, cet essai évalue l'efficacité, du point de vue de la réduction de la douleur neuropathique liée aux rayonnements ionisants, et la toxicité de la prégabaline

Effect of Pregabalin on Radiotherapy-Related Neuropathic Pain in Patients With Head and Neck Cancer: A Randomized Controlled Trial

Jiang, Jingru ; Li, Yi ; Shen, Qingyu ; Rong, Xiaoming ; Huang, Xiaolong ; Li, Honghong ; Zhou, Lizhi ; Mai, Hai-Qiang ; Zheng, Dong ; Chen, Ming-Yuan ; Xu, Yongteng ; Li, Jibin ; Hui, Xuan ; Simone, Charles B. ; Gaertner, Jan ; Argyriou, Andreas A. ; Chow, Edward ; Chen, Pingyan ; Tang, Yamei

Purpose : Neuropathic pain is an unavoidable treatment-related adverse event among patients with head and neck cancer who are undergoing radiotherapy. We aimed to test the efficacy and safety of pregabalin versus placebo in the treatment of radiotherapy-related neuropathic pain. Patients and Methods : This randomized, double-blind, placebo-controlled trial was conducted in four centers in China. Eligible patients with a mean pain intensity score of 4 or more on an 11-point numeric rating scale [...]

Menée à partir de données portant sur 4 065 patients européens atteints d'une seconde tumeur solide après une greffe de cellules souches hématopoïétiques, cette étude analyse la survie globale en fonction de la localisation de la tumeur ainsi que les causes de décès

Evaluation of second solid cancers after hematopoietic stem cell transplantation in European patients

Tichelli, A. ; Beohou, E. ; Labopin, M. ; et al.,

Importance : Incidence and risk factors of second solid cancers (SSCs) that occur after hematopoietic stem cell transplantation (HSCT) are well documented. However, clinical outcome data of patients who developed an SSC after HSCT are limited. Objective : To assess the outcome of patients with an SSC occurring after HSCT from the time of SSC diagnosis. Design, Setting, and Participants : This cohort study used data of 4065 patients from 26 countries registered with the European Society for [...]

A partir des données des registres américains des cancers sur la période 2004-2015, cette étude analyse les facteurs associés à la survie et à la mortalité par cancer chez des patients atteints d'un myélome et ayant développé un second cancer (sein, prostate, poumon, côlon-rectum, vessie, mélanome)

Outcomes of secondary solid tumor malignancies among patients with myeloma: A population-based study

Barth, Peter ; Castillo, Jorge J. ; Olszewski, Adam J.

Background : Therapeutic advances have extended survival for patients with myeloma, who may develop secondary cancers. Methods : Using the population-based Surveillance, Epidemiology, and End Results registry (2004-2015), the authors examined the characteristics, overall and cause-specific survival, and cumulative incidence function of cancer-related death among patients with myeloma with secondary cancers of the breast, prostate, lung, colon/rectum, or bladder or melanoma. Each patient was [...]

A partir des données 2004-2011 des registres américains des cancers portant sur 8 025 patients ayant survécu à un cancer de la tête et du cou non lié à une infection par le papillomavirus humain (HPV) et sur 2 499 patients ayant survécu à un cancer de la tête et du cou lié à une infection par le HPV, cette étude analyse la présence de comorbidités et leur impact sur la survie

Prevalence of comorbidities and effect on survival in survivors of human papillomavirus–related and human papillomavirus–unrelated head and neck cancer in the United States

Eytan, Danielle F. ; Blackford, Amanda L. ; Eisele, David W. ; Fakhry, Carole

Background :The increasing incidence of human papillomavirus (HPV)–related head and neck cancer (HNC) has led to the increasing prevalence of survivors, yet to the best of the authors’ knowledge the prevalence of comorbidities during the survivorship period and their effects on survival are relatively unknown. Methods : In this retrospective cross-sectional study, individuals with a first incident primary diagnosis of HNC from 2004 through 2011 from the Surveillance, Epidemiology, and End [...]

Menée au Royaume-Uni à partir de l'analyse de plus de 60 heures de discussions enregistrées entre 15 professionnels de santé, 8 patients atteints d'un cancer colorectal traité par capécitabine et 11 membres de leur famille, cette étude analyse l'évolution de la communication relative à la chimiothérapie orale entre le médecin et son patient, depuis le moment du diagnostic jusqu'à la fin des traitements

From telling to sharing to silence: A longitudinal ethnography of professional-patient communication about oral chemotherapy for colorectal cancer

Mitchell, Gary ; Porter, Sam ; Manias, Elizabeth

Background : Healthcare professionals are encouraged to promote concordance, a shared agreement about prescription and administration of medications, in their communication with patients. However, there is a paucity of research regarding the impact of communication about self-administered oral chemotherapy. The aim of this study was to examine the changing dynamics of communication through the patient journey from diagnosis of colorectal cancer to post treatment of chemotherapy. Methods : Over [...]