Menée aux Etats-Unis auprès de 186 patientes atteintes d'un cancer du sein, cette étude de cohorte observationnelle évalue les effets d'une hormonothérapie adjuvante sur l'évolution de leurs symptômes (dépression, fatigue, troubles du sommeil, etc) 6 et 12 mois après le début des traitements, ainsi que sur leur qualité de vie

Impact of Adjuvant Endocrine Therapy on Quality of Life and Symptoms: Observational Data Over 12 Months From the Mind-Body Study

Ganz, Patricia A. ; Petersen, Laura ; Bower, Julienne E. ; Crespi, Catherine M.

Purpose : To examine patterns of health and symptoms associated with the initiation of adjuvant endocrine therapy (ET) for primary breast cancer treatment. Patients and Methods : The mind-body study (MBS) observational cohort participants provided self-reported data on physical and mental health, ET-related symptoms, as well as depression, fatigue, and sleep obtained at enrollment (after primary treatment, prior to initiation of ET) and 6 and 12 months later. Longitudinal trajectories of [...]

Menée en Norvège auprès de 2 687 patients masculins ayant survécu à un cancer diagnostiqué durant l'enfance, l'adolescence ou au début de l'âge adulte (naissance entre 1965 et 1985), cette étude de cohorte évalue l'impact de la maladie sur leur situation maritale et leur paternité

Reproduction and marriage among male survivors of cancer in childhood, adolescence and young adulthood: a national cohort study

Gunnes, M. W. ; Lie, R. T. ; Bjorge, T. ; Ghaderi, S. ; Ruud, E. ; Syse, A. ; Moster, D.

Background: Increased survival after cancer in young age has made long-term follow-up studies of high external validity important. In this national cohort study, we explored the impact of cancer in young age on reproduction and marital status in male survivors. Methods: Hazard ratios (HRs) and relative risks (RRs) of reproductive and marital outcomes were studied for male survivors of cancer in young age (<25 years) and cancer-free male comparisons, born during 1965–1985, by linking compulsory [...]

Menée aux Pays-Bas auprès de 134 patients atteints de cancer, cette étude prospective randomisée évalue l'efficacité d'un dispositif de refroidissement du cuir chevelu pour prévenir une alopécie induite par la chimiothérapie par docétaxel, en prenant en compte la durée du refroidissement après le traitement

Results of 20- versus 45-min post-infusion scalp cooling time in the prevention of docetaxel-induced alopecia

Komen, Manon M. C. ; Breed, Wim P. M. ; Smorenburg, Carolien H. ; Ploeg, Tjeerd ; Goey, S. H. ; Hoeven, Jacobus J. M. ; Nortier, Johan W. R. ; Hurk, Corina J. G.

Purpose : For patients, chemotherapy-induced alopecia (CIA) is one of the most distressing side effects of treatment. Scalp cooling can prevent or minimise CIA; the results may depend on the duration of cooling. Since a previous study on post-infusion cooling time in patients treated with docetaxel chemotherapy found no difference between 90 and 45 min, we investigated whether hair-preserving results could be maintained with a shorter post-infusion cooling time. Methods : In this prospective, [...]

Menée aux Etats-Unis auprès de 38 patients ayant survécu à un cancer du rectum ou de la vessie, cette étude pilote évalue l'efficacité d'un programme facilitant leur autonomie dans la prise en charge de leur stomie

A chronic care ostomy self-management program for cancer survivors

Krouse, Robert S. ; Grant, Marcia ; McCorkle, Ruth ; Wendel, Christopher S. ; Cobb, Martha D. ; Tallman, Nancy J. ; Ercolano, Elizabeth ; Sun, Virginia ; Hibbard, Judith H. ; Hornbrook, Mark C.

Background : Individuals with ostomies experience extensive changes in health-related quality of life (HRQOL) and daily routine. Patients and families are typically forced to use trial and error to improve self-management. Methods : This is a longitudinal one-group design pilot study of a five-session ostomy self-care curriculum based on the Chronic Care Model to improve HRQOL and self-management for cancer survivors with ostomies. Participants were surveyed to evaluate each session. Multiple [...]

Menée en Italie auprès de 205 patients adolescents et jeunes adultes ayant survécu à un cancer et 205 témoins, cette étude analyse leur qualité de vie et leurs perceptions relatives au soutien social

Perceived social support and health-related quality of life in AYA cancer survivors and controls

Tremolada, Marta ; Bonichini, Sabrina ; Basso, Giuseppe ; Pillon, Marta

Background : This study compared education levels, health-related quality of life (HRQoL) and perceived social support of adolescent and young adult (AYA) cancer survivors with those of a control group of peers with no history of serious illness. The links between socio-demographic and medical factors and AYA cancer survivor outcomes were investigated. Methods : The participants included AYA cancer survivors (n = 205) recruited during follow-up visits, and AYA peers (n = 205) recruited from the [...]

Menée en Allemagne auprès de 714 patients atteints d'un cancer de la prostate, cette étude analyse l'efficacité d'un programme destiné à améliorer leur santé physique et psychique, et à les aider à réintégrer une vie sociale, après une prostatectomie radicale

Psychosocial and physical outcomes of in- and outpatient rehabilitation in prostate cancer patients treated with radical prostatectomy

Rath, Hilke M. ; Ullrich, Anneke ; Otto, Ullrich ; Kerschgens, Christa ; Raida, Martin ; Hagen-Aukamp, Christa ; Koch, Uwe ; Bergelt, Corinna

Purpose : A radical prostatectomy might lead to an impaired quality of life. Aim of the study was to analyse the impact of inpatient and outpatient rehabilitation on psychosocial and physical outcomes in patients after surgery. Methods : Six hundred nineteen inpatients and 95 outpatients, treated for localized prostate cancer by prostatectomy, completed the Hospital Anxiety and Depression Scale (HADS) and two quality-of-life questionnaires (EORTC QLQ-C30 and EORTC QLQ-PR25) at the beginning and [...]

Mené aux Etats-Unis auprès de 61 patientes ayant survécu à un cancer du sein, cet essai randomisé évalue les facteurs associés à leur adhésion à des sessions d'exercices physiques destinés à soulager les douleurs articulaires induites par les traitements à base d'inhibiteurs de l'aromatase

Exercise adherence in a randomized trial of exercise on aromatase inhibitor arthralgias in breast cancer survivors: the Hormones and Physical Exercise (HOPE) study

Arem, Hannah ; Sorkin, Mia ; Cartmel, Brenda ; Fiellin, Martha ; Capozza, Scott ; Harrigan, Maura ; Ercolano, Elizabeth ; Zhou, Yang ; Sanft, Tara ; Gross, Cary ; Schmitz, Kathryn ; Neogi, Tuhina ; Hershman, Dawn ; Ligibel, Jennifer ; Irwin, Melinda L.

Purpose : Up to 50 % of postmenopausal breast cancer survivors taking aromatase inhibitors (AIs) experience AI-associated arthralgias, or joint pain, which causes many to stop taking AIs and may inhibit exercise, despite known health benefits. We thus evaluated exercise adherence and factors associated with better exercise adherence in breast cancer survivors experiencing AI-induced arthralgia in the (HOPE) year long randomized controlled trial. Methods : We included 61 HOPE women randomized to [...]

Menée aux Etats-Unis par entretiens auprès de 21 patientes ayant survécu à un cancer du sein, cette étude analyse les facteurs facilitant ou entravant leur autonomie dans les soins de leur lymphœdème, ainsi que leurs besoins en soins de support

Breast cancer survivors’ perspectives of critical lymphedema self-care support needs

Ridner, Sheila H. ; Rhoten, Bethany A. ; Radina, M. Elise ; Adair, Melissa ; Bush-Foster, Sydney ; Sinclair, Vaughn

Purpose : To solicit breast cancer survivors’ perspectives on the variety of issues they face related to lymphedema self-care and identify support needs perceived as critical for managing their chronic medical condition. Methods : Twenty-one breast cancer survivors with lymphedema participated in audio-recorded focus groups about barriers and facilitators of self-care. Transcripts were analyzed using ATLAS.ti software by two coders. Triangulation of findings provided for refinement and category [...]

A partir des données du registre national des cancers en Chine, cette étude présente les prévisions d'incidence de cancer et de mortalité spécifique pour l'année 2015 (4 292 000 nouveaux cas de cancer, 2 814 000 décès par cancer)

Cancer statistics in China, 2015

Chen, Wanqing ; Zheng, Rongshou ; Baade, Peter D. ; Zhang, Siwei ; Zeng, Hongmei ; Bray, Freddie ; Jemal, Ahmedin ; Yu, Xue Qin ; He, Jie

With increasing incidence and mortality, cancer is the leading cause of death in China and is a major public health problem. Because of China's massive population (1.37 billion), previous national incidence and mortality estimates have been limited to small samples of the population using data from the 1990s or based on a specific year. With high-quality data from an additional number of population-based registries now available through the National Central Cancer Registry of China, the authors [...]

Menée aux Etats-Unis à partir de données portant sur 1 869 patients ayant survécu à un cancer traité à l'aide d'une greffe de cellules souches hématopoïétiques (âge moyen : 56 ans), cette étude analyse les facteurs cliniques et sociodémographiques associés au risque de dépression et de fatigue

Risk factors for depression and fatigue among survivors of hematopoietic cell transplantation

Jim, Heather S. L. ; Sutton, Steven K. ; Jacobsen, Paul B. ; Martin, Paul J. ; Flowers, Mary E. ; Lee, Stephanie J.

BACKGROUND Patients treated with hematopoietic cell transplantation (HCT) often experience depression and fatigue but analyses to determine risk factors have typically lacked statistical power. The current study examined sociodemographic and clinical risk factors for depression and fatigue in a large cohort of survivors of HCT. METHODS Measures of depression and fatigue were included in an annual survey of HCT recipients that also included self-reported sociodemographic and health information. [...]

Menée aux Etats-Unis à partir de données portant sur 9 958 participants, cette étude analyse les disparités, en fonction de l'orientation sexuelle, dans les comportements associés à un risque de cancer (tabagisme, consommation d'alcool, alimentation, activité physique, maladies sexuellement transmissibles, exposition solaire, etc)

Disparities by Sexual Orientation in Frequent Engagement in Cancer-Related Risk Behaviors: A 12-Year Follow-Up

Rosario, Margaret ; Li, Fei ; Wypij, David ; Roberts, Andrea L. ; Corliss, Heather L. ; Charlton, Brittany M. ; Frazier, A. Lindsay ; Austin, S. Bryn

Objectives : We examined sexual-orientation disparities in frequent engagement in cancer-related risk indicators of tobacco, alcohol, diet and physical activity, ultraviolet radiation, and sexually transmitted infections (STIs). Methods : We used longitudinal data from the national Growing Up Today Study (1999-2010). Of the analytic sample (n=9958), 1.8% were lesbian or gay (LG), 1.6% bisexual (BI), 12.1% mostly heterosexual (MH), and 84.5% completely heterosexual (CH). Results : More sexual [...]

A partir des données du registre norvégien des cancers portant sur 258 675 patients atteints d'un cancer diagnostiqué entre 2002 et 2011, cette étude analyse les disparités régionales de survie, en prenant en compte le stade de la tumeur au diagnostic, le statut socio-économique des patients, les comorbidités et les traitements reçus

Regional variations in cancer survival: Impact of tumour stage, socioeconomic status, comorbidity and type of treatment in Norway

Skyrud, Katrine Damgaard ; Bray, Freddie ; Eriksen, Morten Tandberg ; Nilssen, Yngvar ; Møller, Bjørn

Cancer survival varies by place of residence, but it remains uncertain whether this reflects differences in tumour, patient and treatment characteristics (including tumour stage, indicators of socioeconomic status (SES), comorbidity and information on received surgery and radiotherapy) or possibly regional differences in the quality of delivered health care. National population-based data from the Cancer Registry of Norway were used to identify cancer patients diagnosed in 2002–2011 [...]

Menée à partir de données portant sur des patients ayant survécu à un cancer de l'enfance, cette étude d'association sur le génome entier évalue l'association entre des polymorphismes à simple nucléotide du gène CELF4 et le risque de cardiomyopathie liée à la chimiothérapie par anthracyclines

CELF4 Variant and Anthracycline-Related Cardiomyopathy: A Children’s Oncology Group Genome-Wide Association Study

Wang, Xuexia ; Sun, Can-Lan ; Quiñones-Lombraña, Adolfo ; Singh, Purnima ; Landier, Wendy ; Hageman, Lindsey ; Mather, Molly ; Rotter, Jerome I. ; Taylor, Kent D. ; Chen, Yii-Der Ida ; Armenian, Saro H. ; Winick, Naomi ; Ginsberg, Jill P. ; Neglia, Joseph P. ; Oeffinger, Kevin C. ; Castellino, Sharon M. ; Dreyer, ZoAnn E. ; Hudson, Melissa M. ; Robison, Leslie L. ; Blanco, Javier G. ; Bhatia, Smita

Purpose : Interindividual variability in the dose-dependent association between anthracyclines and cardiomyopathy suggests that genetic susceptibility could play a role. The current study uses an agnostic approach to identify genetic variants that could modify cardiomyopathy risk. Methods : A genome-wide association study was conducted in childhood cancer survivors with and without cardiomyopathy (cases and controls, respectively). Single-nucleotide polymorphisms (SNPs) that surpassed a [...]

A partir des données de l'Organisation Mondiale de la Santé et de la base Eurostat, cette étude présente les projections de mortalité par cancer pour l'année 2016 en Europe

European cancer mortality predictions for the year 2016 with focus on leukemias

Malvezzi, M. ; Carioli, G. ; Bertuccio, P. ; Rosso, T. ; Boffetta, P. ; Levi, F. ; La Vecchia, C. ; Negri, E.

Background : Current cancer mortality statistics are important for public health decision making and resource allocation. Age standardized rates and numbers of deaths are predicted for 2016 in the European Union. Patients and methods : Population and death certification data for stomach, colorectum, pancreas, lung, breast, uterus, prostate, leukemia and total cancers were obtained from the World Health Organisation database and Eurostat. Figures were derived for the EU, France, Germany, Italy, [...]

A partir des données des registres américains des cancers portant sur 13 107 patients atteints d'un lymphome périphérique à cellules T, cette étude analyse les disparités ethniques dans l'incidence de cancer et la survie des patients

Racial Patterns of Peripheral T-Cell Lymphoma Incidence and Survival in the United States

Adams, Scott V. ; Newcomb, Polly A. ; Shustov, Andrei R.

Purpose : To compare incidence and survival of peripheral T-cell lymphoma (PTCL) subtypes among US racial/ethnic groups. Methods : Patients with PTCL (age ≥ 15 years; 2000 to 2012) were identified in the Surveillance, Epidemiology, and End Results (SEER) registries. Race/ethnicity was categorized as non-Hispanic white, black, Asian/Pacific Islander, Hispanic white, or American Indian/Alaskan native. Age-standardized annual incidence rates and incidence rate ratios were estimated with 95% CIs, [...]

Menée en Australie, cette étude analyse l'évolution de l'incidence du mésothéliome malin de la plèvre et du péritoine, ainsi que la survie des patients, sur la période 1982-2009

Incidence and survival trends for malignant pleural and peritoneal mesothelioma, Australia, 1982–2009

Soeberg, Matthew J ; Leigh, James ; Driscoll, Tim ; Armstrong, Bruce ; Young, Jane M ; van Zandwijk, Nico

Background : Australia is known to have had one of the highest per-capita asbestos consumption rates, yet there are few contemporary reports on malignant mesothelioma trends. Methods : Data on 10 930 people with malignant pleural mesothelioma (MPM) and 640 people with malignant peritoneal mesothelioma diagnosed in Australia during 1982–2009 were analysed. Observed incidence rate trends were quantified. Incidence rates were projected up to 2030 using observed incident cases during 1982–2012. The [...]

A partir des données d'études d'association sur le génome entier précédemment publiées, cette étude évalue l'association entre 1 245 polymorphismes à simple nucléotide de gènes liés à 4 familles de transporteurs membranaires et à 2 familles d'enzymes du métabolisme, et la survie, chez des patients atteints d'un cancer du poumon non à petites cellules

Genetic variants in ABCG1 are associated with survival of non small-cell lung cancer patients

Wang, Yanru ; Liu, Hongliang ; Ready, Neal E. ; Su, Li ; Wei, Yongyue ; Christiani, David C. ; Wei, Qingyi

Cell membrane transporters and metabolic enzymes play a crucial role in the transportation of a wide variety of substrates that maintain homeostasis in biological processes. We explored associations between genetic variants in these genes and survival of nonsmall-cell lung cancer (NSCLC) patients by reanalyzing two datasets from published genome-wide association studies (GWASs). In the discovery by using the GWAS dataset of the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening [...]

Menée aux Etats-Unis à partir de données portant sur 628 patients afro-américains atteints d'un cancer de la prostate et sur 1 020 patients d'une autre origine ethnique, cette étude analyse les disparités ethniques dans l'association entre le niveau sérique de cholestérol mesuré avant une prostatectomie radicale et le risque de récidive de la maladie

Racial differences in the association between preoperative serum cholesterol and prostate cancer recurrence: results from the SEARCH database

Allott, Emma H ; Howard, Lauren E. ; Aronson, William J. ; Terris, Martha K. ; Kane, Christopher J. ; Amling, Christopher L. ; Cooperberg, Matthew R. ; Freedland, Stephen J.

Background:Black men are disproportionately affected by both cardiovascular disease and prostate cancer. Epidemiologic evidence linking dyslipidemia, an established cardiovascular risk factor, and prostate cancer progression is mixed. As existing studies were conducted in predominantly non-black populations, research in black men is lacking. Methods:We identified 628 black and 1,020 non-black men who underwent radical prostatectomy and never used statins before surgery in the Shared Equal [...]

A partir des données des registres américains portant sur 258 024 patients atteints d'un cancer colorectal diagnostiqué avant l'âge de 50 ans entre 1998 et 2011, cette étude de cohorte rétrospective analyse les traitements reçus et leur survie

Colorectal cancer outcomes and treatment patterns in patients too young for average-risk screening

Abdelsattar, Zaid M. ; Wong, Sandra L. ; Regenbogen, Scott E. ; Jomaa, Diana M. ; Hardiman, Karin M. ; Hendren, Samantha

BACKGROUND Although colorectal cancer (CRC) screening guidelines recommend initiating screening at age 50 years, the percentage of cancer cases in younger patients is increasing. To the authors' knowledge, the national treatment patterns and outcomes of these patients are largely unknown. METHODS The current study was a population-based, retrospective cohort study of the nationally representative Surveillance, Epidemiology, and End Results registry for patients diagnosed with CRC from 1998 [...]

Menée aux Etats-Unis à partir des données d'une cohorte prospective longitudinale incluant 20 691 patientes atteintes d'un cancer du sein (âge : de 20 à 79 ans), cette étude évalue l'impact du tabagisme, avant et après le diagnostic, sur le risque de décès par cancer du sein et sur le risque de maladies associées au tabac (cardiovasculaires, respiratoires)

Cigarette Smoking Before and After Breast Cancer Diagnosis: Mortality From Breast Cancer and Smoking-Related Diseases

Passarelli, Michael N. ; Newcomb, Polly A. ; Hampton, John M. ; Trentham-Dietz, Amy ; Titus, Linda J. ; Egan, Kathleen M. ; Baron, John A. ; Willett, Walter C.

Purpose : Cigarette smoking increases overall mortality, but it is not established whether smoking is associated with breast cancer prognosis. Methods : We evaluated the association between smoking status before and after breast cancer diagnosis and mortality in the Collaborative Breast Cancer and Women’s Longevity Study, a population-based prospective observational study conducted in Wisconsin, New Hampshire, and Massachusetts. Participants included 20,691 women, ages 20 to 79 years, diagnosed [...]

A partir des données des registres américains des cancers portant sur 31 425 patientes atteintes d'un cancer du col de l'utérus diagnostiqué entre 2000 et 2010, cette étude évalue les effets du statut marital sur le stade au diagnostic et sur la survie

The effect of marriage on stage at diagnosis and survival in women with cervical cancer

El Ibrahimi, Sanae ; Pinheiro, Paulo S.

Purpose : This study assessed the effect of marital status on stage at diagnosis and survival in women with cervical cancer. Methods : Cervical cancer cases diagnosed between 2000 and 2010 were identified from the Surveillance, Epidemiology and End Results (SEER) program. Patient demographic and clinical characteristics were compared by marital status. Multivariate logistic and Cox proportional hazard regression models were performed to calculate odds ratios of advanced stage at diagnosis and [...]

A partir d'une revue systématique de la littérature (16 études), cette étude présente un nouveau concept pour analyser la peur de la récidive chez les patients ayant survécu à un cancer

Fear of cancer recurrence: a theoretical review and novel cognitive processing formulation

Fardell, Joanna E. ; Thewes, Belinda ; Turner, Jane ; Gilchrist, Jemma ; Sharpe, Louise ; Smith, Allan ‘Ben’ ; Girgis, Afaf ; Butow, Phyllis

Purpose : Fear of cancer recurrence (FCR) is prevalent among survivors. However, a comprehensive and universally accepted theoretical framework of FCR to guide intervention is lacking. This paper reviews theoretical frameworks previously used to explain FCR and describes the formulation of a novel theoretical framework for FCR. Methods : A systematic review of the literature was undertaken to identify conceptual frameworks or theories applied to FCR. MEDLINE, PubMED, CINAHL, AMED, PsycINFO and [...]

Menée au Canada par enquête auprès de 184 survivants d'un cancer pédiatrique et âgés de 15 à 19 ans, cette étude analyse les facteurs associés à leurs capacités de se prendre en charge lors de la transition entre les soins pédiatriques et les soins de suivi à long terme dédiés aux adultes

Examining factors associated with self-management skills in teenage survivors of cancer

Syed, Iqra A. ; Nathan, Paul C. ; Barr, Ronald ; Rosenberg-Yunger, Zahava R. S. ; D’Agostino, Norma M. ; Klassen, Anne F.

Background : Monitoring long-term health of teenage cancer survivors is dependent on successful transition from pediatric to adult long-term follow-up (LTFU) care. This study identified factors associated with self-management skills (SMSs), an important correlate of successful transition. Methods : Data were collected from a cross-sectional survey conducted at three Canadian hospitals between July 2011 and January 2012. The sample included 184 childhood cancer survivors aged between 15 and 19 [...]

Menée au Canada par questionnaire auprès de 157 patientes ayant survécu à un cancer du sein (âge moyen : 55 ans ; durée de suivi : 11 ans), cette étude évalue l'association entre l'évolution du soutien social après le diagnostic et les traitements et le bien-être psychologique des patientes

Changes in social support predict emotional well-being in breast cancer survivors

Fong, Angela J. ; Scarapicchia, Tanya M. F. ; McDonough, Meghan H. ; Wrosch, Carsten ; Sabiston, Catherine M.

Background : Breast cancer survivors who have completed surgery and adjuvant treatment have distinct social support needs that may relate to emotional health. There is little research on both levels of social support following treatment and the association between social support and emotional well-being over time following breast cancer diagnosis and treatment. The aims of this study were to assess (1) the direction and magnitude of change in social support quality and quantity and (2) the [...]

A partir d'une revue systématique de la littérature (8 études, 1 668 patients), cette étude analyse le rapport coût-efficacité des interventions psychosociales pour les patients atteints de cancer

Economic evaluations of psychosocial interventions in cancer: a systematic review

Dieng, Mbathio ; Cust, Anne E. ; Kasparian, Nadine A. ; Mann, Graham J. ; Morton, Rachael L.

Objective : Although the effectiveness of many psychosocial interventions for people with cancer has been established, one barrier to implementation in routine clinical care is a lack of data on cost-effectiveness. We conducted a systematic review to assess the cost-effectiveness of psychosocial interventions for improving psychological adjustment among people with cancer. Methods : A systematic review of the literature, study appraisal and narrative synthesis. Results : Eight studies involving [...]

A partir des données des registres américains des cancers portant sur 231 596 patients atteints d'un cancer diagnostiqué entre 1995 et 2009, cette étude montre que des difficultés financières importantes sont un facteur de risque de mortalité prématurée

Financial Insolvency as a Risk Factor for Early Mortality Among Patients With Cancer

Ramsey, Scott D. ; Bansal, Aasthaa ; Fedorenko, Catherine R. ; Blough, David K. ; Overstreet, Karen A. ; Shankaran, Veena ; Newcomb, Polly

Purpose : Patients with cancer are more likely to file for bankruptcy than the general population, but the impact of severe financial distress on health outcomes among patients with cancer is not known. Methods : We linked Western Washington SEER Cancer Registry records with federal bankruptcy records for the region. By using propensity score matching to account for differences in several demographic and clinical factors between patients who did and did not file for bankruptcy, we then fit Cox [...]

Menée aux Etats-Unis à partir de données portant sur 96 patients âgés de 14 à 26 ans et ayant reçu une greffe de cellules souches hématopoïétiques entre 2011 et 2015, cette étude analyse l'association entre le contenu des directives anticipées écrites par le patient et la nature des soins de fin de vie administrés aux adolescents et jeunes adultes atteints de cancer

The Impact of Advance Directives on End-of-Life Care for Adolescents and Young Adults Undergoing Hematopoietic Stem Cell Transplant

Needle, Jennifer ; Smith, Angela R.

Background: Little is known about the role of advance directives (AD) in end-of-life (EOL) care for adolescents and young adults (AYA) undergoing hematopoietic stem cell transplant (HSCT). Objective: The study objective was to describe the frequency, type, and influence of AD on the use of life-sustaining treatment (LST) in AYA patients undergoing HSCT. Methods: We performed a retrospective chart review of 96 patients aged 14-26 undergoing HSCT between April 2011 and January 2015 at the [...]