Menée en Espagne auprès de 261 patients atteints de cancer (âge médian : 64 ans), cette étude analyse l'incidence des nausées et vomissements induits par une chimiothérapie modérément émétisante et leur prise en charge médicale

Incidence of chemotherapy-induced nausea and vomiting with moderately emetogenic chemotherapy: ADVI CE (Actual Data of Vomiting Incidence by Chemotherapy Evaluation) study

Camacho, Isabel ; Escobar, Yolanda ; Cajaraville, Gerardo ; Virizuela, JuanAntonio ; Álvarez, Rosa ; Muñoz, Andrés ; Olariaga, Olatz ; Tamés, MaríaJosé ; Muros, Begoña ; Lecumberri, MaríaJose ; Feliu, Jaime ; Martínez, Purificación ; Adansa, JuanCarlos ; Martínez, MaríaJosé ; López, Rafael ; Blasco, Ana ; Gascón, Pere ; Calvo, Virginia ; Luna, Pablo ; Montalar, Joaquín ; Del Barrio, Patricia ; Tornamira, MaríaVictoria

Purpose : This study aims to determine the incidence of nausea and vomiting (CINV) after moderately emetogenic chemotherapy (MEC), under medical practice conditions and the accuracy with which physicians perceive CINV. Methods : Chemotherapy-naive patients receiving MEC between April 2012 and May 2013 were included. Patients completed a diary of the intensity of nausea and number of vomiting episodes. Complete response and complete protection were assessed as secondary endpoints. Results : Of [...]

Menée en Australie auprès de 463 patients ayant survécu à un cancer de la prostate, cette étude de cohorte analyse l'association entre leur observance des recommandations relatives à la pratique d'exercices physiques et leur détresse psychologique, leurs besoins en soins de support et leur qualité de vie

Compliance to exercise-oncology guidelines in prostate cancer survivors and associations with psychological distress, unmet supportive care needs, and quality of life

Galvão, Daniel A. ; Newton, Robert U. ; Gardiner, Robert A. ; Girgis, Afaf ; Lepore, Stephen J. ; Stiller, Anna ; Mihalopolous, Cathrine ; Occhipinti, Stefano ; Chambers, Suzanne K.

Objective : The purpose of this study was to determine prevalence of Australian prostate cancer survivors meeting contemporary exercise-oncology guidelines and identify associations with distress, unmet supportive care needs, and quality of life. Methods : A population-based cohort of 463 prostate cancer survivors who were on 10.8 months post-curative therapy was assessed for compliance with current exercise guidelines for cancer survivors, motivational readiness for physical activity, [...]

Menée au Canada à partir de données portant sur 195 patientes ayant survécu à un cancer du sein, cette étude analyse les effets d'une activité physique, d'intensité modérée à intense, pour améliorer leur santé physique et psychologique

Physical and psychological health among breast cancer survivors: interactions with sedentary behavior and physical activity

Trinh, Linda ; Amireault, Steve ; Lacombe, Jason ; Sabiston, Catherine M.

Background : Reducing sedentary behavior (SED) may be one promising strategy to reduce treatment-related side effects in breast cancer given the unique health benefits distinct from the beneficial effects of moderate-to-vigorous intensity physical activity (MVPA). Objectives : To examine the associations between SED and the late-effects symptoms of pain, fatigue, and depression among breast cancer survivors (BCS), and the interactive associations between SED, light PA, and MVPA on these [...]

Menée auprès de 223 patientes atteintes d'un cancer du sein de stade avancé ou métastatique, cette étude évalue l'efficacité d'un questionnaire pour évaluer les symptômes du syndrome mains-pieds, une réaction inflammatoire induite par les agents de chimiothérapie, et la qualité de vie des patientes

The Hand-Foot Skin Reaction and Quality of Life Questionnaire: An Assessment Tool for Oncology

Anderson, Roger T. ; Keating, Karen N. ; Doll, Helen A. ; Camacho, Fabian

Skin toxicity (hand-foot syndrome/hand-foot skin reaction, HFS/R) related to antineoplastic therapy is a significant issue in oncology practice, with potentially large impacts on health-related quality of life (HRQL).A patient-reported questionnaire, the hand-foot skin reaction and quality of life (HF-QoL) questionnaire was developed to measure the HFS/R symptoms associated with cancer therapeutic agents and their effect on daily activities. The validity and reliability of the HF-QoL [...]

Menée au Royaume-Uni par questionnaire auprès de 160 participantes, cette étude analyse leurs perceptions (douleur physique, anxiété) après un premier examen de dépistage par colposcopie

Patients’ perceptions of colposcopy pain

Kola-Palmer, S. ; Walsh, J. C. ; Rogers, M.

This study aimed to examine the sensory descriptors used by women undergoing their first ever colposcopy examination as part of cervical cancer screening. Immediately following colposcopy, women were asked to provide detailed information about the sensory, affective, evaluative and intensity properties of the colposcopy examination using a validated, standardised questionnaire. Overall, 160 colposcopy patients with different management options were assessed [53 women underwent diagnostic [...]

Menée à partir de données portant sur 103 patients atteints de cancer, cette étude analyse les effets d'une activité physique sur la survie après une greffe allogénique de cellules souches hématopoïétiques

Effects of physical exercise on survival after allogeneic stem cell transplantation

Wiskemann, Joachim ; Kleindienst, Nikolaus ; Kuehl, Rea ; Dreger, Peter ; Schwerdtfeger, Rainer ; Bohus, Martin

Observational studies have suggested that physical activity may be associated with improved survival after cancer treatment. However, data from controlled clinical trials are required. We analyzed survival data of 103 patients from a previously published randomized controlled trial in allogeneic stem cell transplant patients who were randomized to either an exercise intervention (EX) or to a social contact control group. EX patients trained prior to hospital admission, during inpatient [...]

Menée aux Etats-Unis par questionnaire auprès de 194 patients atteints de cancer et ayant des enfants de moins de 18 ans, cette étude transversale analyse leurs préoccupations relatives à leur parentalité et leur sentiment d'auto-efficacité pour prendre en charge la détresse émotionnelle de leurs enfants

Parenting changes in adults with cancer

Moore, Cynthia W. ; Rauch, Paula K. ; Baer, Lee ; Pirl, William F. ; Muriel, Anna C.

BACKGROUND Children whose parents have cancer are at risk for psychosocial difficulties; however, the mechanisms are not well understood. This cross-sectional study sought support for a model connecting parental cancer to child distress through its impact on parenting self-efficacy beliefs and parenting behaviors by examining relations among parental illness, quality of life/parent functioning, parenting efficacy beliefs, and concerns about children's emotional distress. METHODS One hundred [...]

Menée aux Etats-Unis auprès de 102 parents d'enfants atteints de cancer, cette étude analyse les effets d'un réseau de soutien social sur leur détresse psychologique

Satisfaction with support versus size of network: differential effects of social support on psychological distress in parents of pediatric cancer patients

Harper, Felicity W. K. ; Peterson, Amy M. ; Albrecht, Terrance L. ; Taub, Jeffrey W. ; Phipps, Sean ; Penner, Louis A.

Objective : This study examined the direct and buffering effects of social support on longer-term global psychological distress among parents coping with pediatric cancer. In both sets of analyses, we examined whether these effects depended on the dimension of social support provided (i.e., satisfaction with support versus size of support network). Method : Participants were 102 parents of pediatric cancer patients. At study entry, parents reported their trait anxiety, depression, and two [...]

Mené en Australie auprès de 429 patients atteints d'un cancer colorectal métastatique et recevant une chimiothérapie de première ligne, cet essai randomisé évalue l'association entre divers indicateurs de l'état psychologique des patients et leur survie (durée médiane de suivi : 31 mois)

Hope, optimism and survival in a randomised trial of chemotherapy for metastatic colorectal cancer

Schofield, PenelopeE ; Stockler, M. R. ; Zannino, D. ; Tebbutt, N. C. ; Price, T. J. ; Simes, R. J. ; Wong, N. ; Pavlakis, N. ; Ransom, D. ; Moylan, E. ; Underhill, C. ; Wyld, D. ; Burns, I. ; Ward, R. ; Wilcken, N. ; Jefford, M.

Purpose : Psychological responses to cancer are widely believed to affect survival. We investigated associations between hope, optimism, anxiety, depression, health utility and survival in patients starting first-line chemotherapy for metastatic colorectal cancer. Methods : Four hundred twenty-nine subjects with metastatic colorectal cancer in a randomised controlled trial of chemotherapy completed baseline questionnaires assessing the following: hopefulness, optimism, anxiety and depression [...]

Cet article présente un cadre d'analyse pour estimer la valeur (une notion combinant bénéfice clinique, toxicité et coûts) d'un traitement du cancer et faciliter la prise de décision entre un médecin et son patient

American Society of Clinical Oncology Statement: A Conceptual Framework to Assess the Value of Cancer Treatment Options

Schnipper, Lowell E. ; Davidson, Nancy E. ; Wollins, Dana S. ; Tyne, Courtney ; Blayney, Douglas W. ; Blum, Diane ; Dicker, Adam P. ; Ganz, Patricia A. ; Hoverman, J. Russell ; Langdon, Robert ; Lyman, Gary H. ; Meropol, Neal J. ; Mulvey, Therese ; Newcomer, Lee ; Peppercorn, Jeffrey ; Polite, Blasé ; Raghavan, Derek ; Rossi, Gregory ; Saltz, Leonard ; Schrag, Deborah ; Smith, Thomas J. ; Yu, Peter P. ; Hudis, Clifford A. ; Schilsky, Richard L.

Health care costs in the United States present a major challenge to the national economic well being. The Centers for Medicare and Medicaid Services (CMS) has projected that US health care spending will reach $4.3 trillion and account for 19.3% of the national gross domestic product by 2019. This growth in spending—both in absolute terms and as a proportion of our gross domestic product—has not been accompanied by commensurate improvements in health outcomes, despite expenditures far exceeding [...]

Menée au Royaume-Uni à partir de données portant sur 298 patients ayant survécu à un cancer 1 an après le diagnostic et ayant terminé un traitement à visée curative (136 cas de cancer du sein, 83 cas de cancer du côlon-rectum, 79 cas de cancer de la prostate), cette étude analyse les coûts associés à l'après-cancer pour la société et pour les patients

The economic burden of cancer in the UK: a study of survivors treated with curative intent

Marti, Joachim ; Hall, Peter S. ; Hamilton, Patrick ; Hulme, Claire T. ; Jones, Helen ; Velikova, Galina ; Ashley, Laura ; Wright, Penny

Objective : We aim to describe the economic burden of UK cancer survivorship for breast, colorectal and prostate cancer patients treated with curative intent, 1 year post-diagnosis. Methods : Patient-level data were collected over a 3-month period 12–15 months post-diagnosis to estimate the monthly societal costs incurred by cancer survivors. Self-reported resource utilisation data were obtained via the electronic Patient-reported Outcomes from Cancer Survivors system and included [...]

Menée aux Etats-Unis par enquête auprès de 3 954 patients atteints d'un cancer du poumon ou du côlon-rectum et ayant subi une résection chirurgicale, cette étude analyse leurs perceptions de la probabilité de guérison

Patient perceptions regarding the likelihood of cure after surgical resection of lung and colorectal cancer

Kim, Yuhree ; Winner, Megan ; Page, Andrew ; Tisnado, Diana M. ; Martinez, Kathryn A. ; Buettner, Stefan ; Ejaz, Aslam ; Spolverato, Gaya ; Morss Dy, Sydney E. ; Pawlik, Timothy M.

BACKGROUND The objective of the current study was to characterize the prevalence of the expectation that surgical resection of lung or colorectal cancer might be curative. The authors sought to assess patient-level, tumor-level, and communication-level factors associated with the perception of cure. METHODS Between 2003 and 2005, a total of 3954 patients who underwent cancer-directed surgery for lung (30.3%) or colorectal (69.7%) cancer were identified from a population-based and health [...]

Menée en Australie par questionnaire auprès de 2 742 participantes (1 109 cas et 1 633 témoins), cette étude analyse leurs perceptions des facteurs de risque de cancer du sein, en fonction de critères démographiques et d'antécédents personnels ou familiaux

Women's beliefs about breast cancer causation in a breast cancer case–control study

Lizama, Natalia ; Rogers, Pierra ; Thomson, Allyson ; Slevin, Terry ; Fritschi, Lin ; Saunders, Christobel ; Heyworth, Jane

Objective : Our study sought to ascertain women's beliefs about breast cancer risk factors and whether these beliefs differed by demographic factors and personal and family history of breast cancer. Methods : Participants in a case–control study of breast cancer rated the effect of 37 exposures on the risk of being diagnosed with breast cancer. Chi-square tests were undertaken to measure differences in responses between cases and controls for each exposure. Logistic regression was undertaken to [...]

Menée par enquête auprès de 47 experts, cette étude internationale présente une liste d'indicateurs permettant de définir et d'évaluer l'intégration de l'oncologie et des soins palliatifs dans des programmes hospitaliers dédiés aux patients atteints d'un cancer de stade avancé

Indicators of Integration of Oncology and Palliative Care Programs: An International Consensus

Hui, D. ; Bansal, S. ; Strasser, F. ; Morita, T. ; Caraceni, A. ; Davis, M. ; Cherny, N. ; Kaasa, S. ; Currow, D. ; Abernethy, A. ; Nekolaichuk, C. ; Bruera, E.

Background : Recently, the concept of integrating oncology and palliative care has gained wide professional and scientific support; however, a global consensus on what constitutes integration is unavailable. We conducted a Delphi Survey to develop a consensus list of indicators of integration of specialty palliative care and oncology programs for advanced cancer patients in hospitals with ≥100 beds. Design : International experts on integration rated a list of indicators on integration over 3 [...]