A partir de données d'enquête menée en ligne auprès de 208 survivantes d'un cancer âgées de 18 à 44 ans, cette étude américaine analyse les facteurs associés à la décision de recourir à des techniques de préservation de fertilité

To preserve or not to preserve

Mersereau, Jennifer E. ; Goodman, Linnea R. ; Deal, Allison M. ; Gorman, Jessica R. ; Whitcomb, Brian W. ; Su, H. Irene

BACKGROUND : The decision to pursue fertility preservation (FP) after a cancer diagnosis is complex. We examined the prevalence of high decisional conflict and specific factors that influence this decision using the Decisional Conflict Scale (DCS). METHODS : The FIRST project is a web-based survey of female cancer survivors (ages 18-44 years) who have undergone gonadotoxic treatment. We evaluated the association between recalled decisional conflict and referral to FP counseling and demographic, [...]

Menée par entretiens auprès de 20 participants, cette étude qualitative nigériane analyse les expériences de patients atteints de leucémie en termes de qualité de vie et de besoins de nature psychosociale

Living with Cancer: A Qualitative Report of the Experiences of Leukaemia Patients in Lagos, Nigeria

Adejoh, SamuelOjima ; Temilola, OlusegunMoses ; Olayiwola, Bolutife

The study examined the qualitative, cognitive and psychosocial experiences of those living with leukaemia undergoing treatment at a teaching hospital. Twenty respondents who consented to participate were purposively selected from the cancer patients with leukaemia receiving treatment in the said teaching hospital. The in-depth interview method was used to collect data. The data was analysed using manual content analysis. Data showed that patients lack basic knowledge about leukaemia and had no [...]

Menée auprès de 186 participants, cette étude transversale canadienne analyse les besoins psychosociaux des patients atteints de cancer colorectal durant la phase de pré-diagnostic

Understanding the Needs of Colorectal Cancer Patients during the Pre-diagnosis Phase

Wiljer, David ; Walton, Tara ; Gilbert, Julie ; Boucher, Amy ; Ellis, PeterM ; Schiff, Susan ; Sellick, ScottM ; Simunovic, Marko ; Kennedy, Erin ; Urowitz, Sara

Patients with colorectal cancer (CRC) face a number of challenges leading up to diagnosis; however, research is limited regarding their specific needs during the pre-diagnosis period. A multicenter cross-sectional survey was conducted to elicit information about the CRC experience during the pre-diagnosis phase. Across the three sites, 104 eligible patients were approached, and 82 patients completed the survey, for a total response rate of 78.9 %. The needs most identified by participants [...]

Menée par enquête auprès de 98 patientes atteintes d'un cancer du sein ayant subi une mastectomie et ayant opté pour une reconstruction mammaire impliquant l'utilisation d'un «lambeau libre DIEP», cette étude analyse l'impact de cette reconstruction sur l'image corporelle de la femme et son degré de satisfaction par rapport à sa vie sexuelle

Impact of delayed implant and DIEP flap breast reconstruction on body image and sexual satisfaction: a prospective follow-up study

Gopie, Jessica P. ; ter Kuile, Moniek M. ; Timman, Reinier ; Mureau, Marc A. M. ; Tibben, Aad

Objective : Prospective studies regarding the psychosexual impact after different types of breast reconstruction (BR) are scarce. The impact of either implant or deep inferior epigastric artery perforator (DIEP) flap BR on body image and sexual relationship satisfaction was investigated in time. Methods : At baseline, 98 women opting for delayed implant or DIEP flap BR after mastectomy for breast cancer completed a survey. The majority was followed up at 6 months (96%) and 20 months (86%) [...]

Menée au Royaume-Uni auprès de 19 patientes atteintes d'un cancer du sein âgées de moins de 45 ans et sans enfant, cette étude qualitative analyse leur vécu relatif à la préservation de leur fertilité avant une chimiothérapie et l'information communiquée par les professionnels de santé sur ce sujet

Young childless women with breast cancer in the UK: a qualitative study of their fertility-related experiences, options, and the information given by health professionals

Corney, Roslyn Heather ; Swinglehurst, Amica Jane

Objective A proportion of young women diagnosed with breast cancer are childless. Fertility can be impaired by treatment, and women may have to wait for a number of years before pregnancy is advised. The aim of this qualitative study was to investigate in detail the fertility-related experiences of young childless women with breast cancer, including the information they received, the fertility preservation options given, and the dilemmas they faced. Method Interviews were conducted with 19 [...]

Cette étude analyse l'évolution de l'incidence des cancers associés au tabagisme en Allemagne sur la période 1999-2008

Changes in cancer incidence attributable to tobacco smoking in Germany, 1999–2008

Wienecke, A. ; Barnes, B. ; Lampert, T. ; Kraywinkel, K.

Tobacco smoking, a major cancer risk factor, is very common in Germany as in many other high-income countries. Few studies have assessed the burden of tobacco-associated cancer incidence in the German population. We calculated the proportion of cancers attributable to tobacco smoking to estimate the burden of tobacco-associated cancer in 1999 and 2008. Smoking prevalence was determined from national surveys of a representative sample of the German population in 1998 and 2008–2011, and data on [...]

Menée auprès de 234 patients atteints d'un lymphome diagnostiqué à l'âge de 90 ans ou plus, cette étude rétrospective analyse les caractéristiques des patients, les traitements reçus ainsi que la survie

Lymphoma occurring in patients over 90 years of age: characteristics, outcomes, and prognostic factors. A retrospective analysis of 234 cases from the LYSA

Trebouet, A. ; Marchand, T. ; Lemal, R. ; Gyan, E. ; Broussais-Guillaumot, F. ; Guillermin, Y. ; Monjanel, H. ; Salles, G. ; Le Gouill, S. ; Godmer, P. ; Fruchart, C. ; Damaj, G. ; Feugier, P. ; Thieblemont, C. ; Maynadié, M. ; Monnereau, A. ; Troussard, X. ; Rossille, D. ; Lamy, T. ; Houot, R.

Background : Lymphoma occurring in patients aged 90 or older is not uncommon, and its incidence is expected to increase over time. Management of these patients is difficult given their underlying fragility and the lack of information regarding this population. Patients and methods : We retrospectively analyzed 234 patients diagnosed with lymphoma at the age of 90 years or older (90+) between 1990 and 2012 to describe their characteristics, management, outcomes and prognostic factors. Results : [...]

Menée en Australie, cette étude évalue l'association entre une exposition au rayonnement solaire UVB au moment du diagnostic, le lieu d'habitation et la survie des patients atteints d'un cancer de la prostate

The association of ultraviolet radiation-B (305 nm), season of diagnosis, and latitude on the survival outcome of prostate cancer in the high UV environment of Australia

Nair-Shalliker, Visalini ; Smith, DavidP ; Egger, Sam ; Clements, MarkS ; Rahman, Md Bayzidur ; Armstrong, BruceK

Background : Positive associations between sun exposure and cancer survival have been observed in regions of high latitudes, where ambient solar ultraviolet (SUV) radiation is generally low. Purpose : We examined the effects of ambient ultraviolet-B radiation (UVB) at time of diagnosis, season of diagnosis and latitude of residence on survival outcome from prostate cancer. Method : Regression models for relative survival were used to estimate relative excess risks (RER) of death after diagnosis [...]

Cette étude américaine passe en revue les travaux récents relatifs à l'impact de l'obésité sur la survie des patientes atteintes d'un cancer du sein ainsi que sur les effets indésirables des traitements, en fonction de leur appartenance éthnique et de la présence de comorbidités

Impact of Obesity on Cancer Survivorship and the Potential Relevance of Race and Ethnicity

Schmitz, Kathryn H. ; Neuhouser, Marian L. ; Agurs-Collins, Tanya ; Zanetti, Krista A. ; Cadmus-Bertram, Lisa ; Dean, Lorraine T. ; Drake, Bettina F.

Evidence that obesity is associated with cancer incidence and mortality is compelling. By contrast, the role of obesity in cancer survival is less well understood. There is inconsistent support for the role of obesity in breast cancer survival, and evidence for other tumor sites is scant. The variability in findings may be due in part to comorbidities associated with obesity itself rather than with cancer, but it is also possible that obesity creates a physiological setting that meaningfully [...]

A partir de données d'enquêtes menées auprès de 66 387 participants vivant dans 13 pays à revenus élévés et dans 11 pays à faibles et moyens revenus, cette étude analyse et compare les comorbidités psychiatriques, les troubles psychiques courants chez des patients atteints de cancer, chez des survivants d'un cancer ou chez des individus non malades ainsi que les disparités en termes de traitements

Comorbidity of common mental disorders with cancer and their treatment gap: findings from the World Mental Health Surveys

Nakash, Ora ; Levav, Itzhak ; Aguilar-Gaxiola, Sergio ; Alonso, Jordi ; Andrade, Laura Helena ; Angermeyer, Matthias C. ; Bruffaerts, Ronny ; Caldas-de-Almeida, Jose Miguel ; Florescu, Slivia ; de Girolamo, Giovanni ; Gureje, Oye ; He, Yanling ; Hu, Chiyi ; de Jonge, Peter ; Karam, Elie G. ; Kovess-Masfety, Viviane ; Medina-Mora, Maria Elena ; Moskalewicz, Jacek ; Murphy, Sam ; Nakamura, Yosikazu ; Piazza, Marina ; Posada-Villa, Jose ; Stein, Dan J. ; Taib, Nezar Ismet ; Zarkov, Zahari ; Kessler, Ronald C. ; Scott, Kate M.

Objective : This study aimed to study the comorbidity of common mental disorders (CMDs) and cancer, and the mental health treatment gap among community residents with active cancer, cancer survivors and cancer-free respondents in 13 high-income and 11 low-middle-income countries. Methods : Data were derived from the World Mental Health Surveys (N = 66,387; n = 357 active cancer, n=1373 cancer survivors, n=64,657 cancer-free respondents). The World Health Organization/Composite International [...]

Menée auprès de 321 patients âgés atteints de cancer et répartis en trois groupes d'âge (60-69 ans, 70-79 ans, 80 ans et +), cette étude analyse la prévalence de leurs symptômes somatiques, dépressifs et anxieux

Depression, anxiety, and somatic symptoms in older cancer patients: a comparison across age groups

Cohen, Miri

Background : Previous studies have reported that older cancer patients experience lower psychological distress than younger patients, but most prior studies do not differentiate between age groups within the ‘older’ category. Aim The aim of this study was to assess the intensity of the symptoms of depression, anxiety, and somatic symptoms among different age groups of older cancer patients. Methods : Participants were composed of 321 cancer patients 60 years and older, who were divided into [...]

Menée auprès de173 participantes, cette étude canadienne analyse les effets du soutien social et du stress sur le bien-être ou la croissance post-traumatique chez des survivantes d'un cancer du sein

Predicting changes in posttraumatic growth and subjective well-being among breast cancer survivors: the role of social support and stress

McDonough, Meghan H. ; Sabiston, Catherine M. ; Wrosch, Carsten

Objective : Social support is theoretically expected to be positively associated with posttraumatic growth (PTG) and subjective well-being, and stress is expected to be positively associated with PTG and negatively associated with subjective well-being among breast cancer (BC) survivors. However, empirical evidence is mixed, predominantly cross-sectional, and few studies have examined the unique effects of these predictors on positive changes in psychological experiences post cancer diagnosis [...]

Menée en Chine auprès de 228 patientes atteintes d'un cancer du sein de stade avancé, cette étude longitudinale analyse l'évolution de leurs symptômes de détresse psychologique et leurs besoins en soins de support

The evolution of psychological distress trajectories in women diagnosed with advanced breast cancer: a longitudinal study

Lam, W. W. T. ; Soong, I. ; Yau, T. K. ; Wong, K. Y. ; Tsang, J. ; Yeo, W. ; Suen, J. ; Ho, W. M. ; Sze, W. K. ; Ng, A. W. Y. ; Kwong, A. ; Suen, D. ; Fielding, R.

Background Anxiety and depression (distress) over the first year following the initial adjuvant therapy for advanced breast cancer (ABC) remain poorly documented in non-Caucasian populations. This study describes trajectories of distress and their determinants in Chinese women with ABC. Methods Of the 228 Chinese women newly diagnosed with ABC recruited from six oncology units, 192 completed an interview before their first course of chemotherapy (baseline) and follow-up interviews at 1.5, 3, 6, [...]

A partir des données du registre coréen d'assurance maladie, cette étude évalue l'incidence des troubles psychiatriques chez des femmes nouvellement diagnostiquées avec un cancer du sein, sur la période 2005-2008

The epidemiology of psychiatric disorders among women with breast cancer in South Korea: analysis of national registry data

Kang, Jee In ; Sung, Na Young ; Park, Sang Jin ; Lee, Chong Gul ; Lee, Byung Ook

Objective : Population-based data on the epidemiology of psychiatric disorders in patients with breast cancer are lacking. Because the National Health Insurance (NHI) Program in South Korea is a compulsory social insurance system covering the entire Korean population, the NHI is a good source of information for epidemiological studies. In the present study, we examined the incidence of psychiatric disorders among Korean women newly diagnosed with breast cancer using the NHI Corporation (NHIC) [...]

Cette étude évalue les coûts financiers associés à l'introduction du pazopanib pour le traitement de première ligne du carcinome à cellules rénales de stade avancé dans le système de santé en Espagne

Budget impact analysis of first-line treatment with pazopanib for advanced renal cell carcinoma in Spain

Villa, Guillermo ; Hernandez-Pastor, Luis-Javier

BACKGROUND:Due to economic constraints, cancer therapies are under close scrutiny by clinicians, pharmacists and payers alike. There is no published pharmacoeconomic evidence guiding the choice of first-line therapy for advanced renal cell carcinoma (RCC) in the Spanish setting. We aimed to develop a model describing the natural history of RCC that can be used in healthcare decision-making. We particularly analyzed the budget impact associated with the introduction of pazopanib compared to [...]

Menée auprès de 32 dyades mère-fille, cette étude propose et analyse deux stratégies de communication pour développer un discours efficace sur les dépistages du cancer du sein et du cancer du col de l'utérus entre une mère et sa fille adolescente

From Adolescent Daughter to Mother: Exploring Message Design Strategies for Breast and Cervical Cancer Prevention and Screening

Mosavel, Maghboeba ; Genderson, MaureenWilson

Early detection of breast and cervical cancers is one preventive behavior that may provide the adolescent daughter with a unique opportunity to provide encouragement to her mother or guardian to obtain screening. This study explored the design strategies necessary for developing an effective daughter-initiated message about screening for breast and cervical cancers. Thirty-two (N= 64) African-American mother–daughter dyads were interviewed about parenting style, goodwill, and daughters’ [...]

Cette étude américaine analyse l'efficacité d'un programme utilisant les médias traditionnels (radio, journaux, télévision) et sociaux (web, twitter,..) pour diffuser de l'information relative au cancer auprès des minorités ethniques

Multicultural Media Outreach: Increasing Cancer Information Coverage in Minority Communities

Alexander, James ; Kwon, HarryT ; Strecher, Rachael ; Bartholomew, Jill

Ethnic media can serve as an opportunity for cancer education and outreach to minority communities. The National Cancer Institute developed the Multicultural Media Outreach (MMO) program which utilizes an integrated approach of both traditional and social media to disseminate evidence-based cancer education information for minority communities. The MMO program is the contact point for multicultural media outlets seeking evidence-based cancer information, education materials, minority [...]

Menée auprès de 55 femmes sourdes et de 52 témoins, cette étude américaine évalue l'efficacité d'une vidéo pédagogique à destination des personnes malentendantes pour développer leurs connaissances relatives au cancer de l'ovaire

Ovarian Cancer: Deaf and Hearing Women’s Knowledge Before and After an Educational Video

Jensen, LindsayG ; Nakaji, Melanie ; Harry, KadieM ; Gallegos, Nick ; Malcarne, VanessaL ; Sadler, GeorgiaRobins

Members of the Deaf community report language and cultural barriers to accessing health information and care. This study evaluated whether an ovarian cancer education video in American Sign Language with English captioning and voice-over could close the anticipated knowledge gap between Deaf and hearing women’s cancer knowledge. Consented Deaf (n = 55) and hearing (n = 52) women’s General, Ovarian, and Total Cancer Knowledge were assessed before and after viewing the video. At baseline, hearing [...]

Menée par entretiens téléphoniques auprès de 14 professionnels de santé, cette étude qualitative canadienne analyse leurs besoins en matière d'information relative au lymphoedème lié aux traitements du cancer du sein

The information needs and media preferences of Canadian cancer specialists regarding breast cancer treatment related arm morbidity

Shaw, R. M. ; Thomas, R.

The information needs and media preferences of Canadian cancer specialists regarding breast cancer treatment related arm morbidity. Breast cancer treatment related arm morbidity is a common but pernicious condition that is under-recognised, under-diagnosed, and can result in long-term impairment and disability. Despite the prevalence of this condition, little is known about breast cancer specialists' information needs and media preferences around this issue. In-depth telephone interviews with [...]

Menée en Belgique auprès de 208 patients atteints de cancer et leurs médecins, cette étude analyse la capacité des médecins généralistes à évaluer et rapporter les difficultés physiques, psychologiques et sociales de leurs patients

The ability of informal primary caregivers to accurately report cancer patients' difficulties

Libert, Yves ; Merckaert, Isabelle ; Slachmuylder, Jean-Louis ; Razavi, Darius

Background : In cancer care, informal primary caregivers provide healthcare professionals with key information regarding patient difficulties. The aim of this study was to assess their ability to report cancer patients' physical, psychological, and social difficulties. Methods : We recruited 208 consecutive patients and their informal primary caregivers in 10 oncology units. Patients reported their difficulties on the CAncer Rehabilitation Evaluation System (CARES-P), whereas caregivers [...]