Menée à Hong Kong auprès de 71 survivants d'un cancer pédiatrique âgés de 9 à 16 ans, cette étude analyse l'efficacité d'un programme d'éducation à la santé visant à promouvoir l'activité physique régulière afin d'améliorer leur qualité de vie

Effectiveness of an integrated adventure-based training and health education program in promoting regular physical activity among childhood cancer survivors

Li, H. C. William ; Chung, Oi Kwan Joyce ; Ho, Ka Yan ; Chiu, Sau Ying ; Lopez, Violeta

Background There is growing concern about declining levels of physical activity in childhood cancer survivors. This study aimed to examine the effectiveness of an integrated adventure-based training and health education program in promoting changes in exercise behavior and enhancing the physical activity levels, self-efficacy, and quality of life of Hong Kong Chinese childhood cancer survivors. Methods A randomized controlled trial, two-group pretest and repeated post-test, between-subjects [...]

Menée au Canada auprès de 43 survivants d'un cancer, cette étude analyse la faisabilité et l'efficacité d'un programme d'activités physiques pour lutter contre une fatigue intense et améliorer leur qualité de vie

Feasibility and efficacy of a supervised exercise intervention in de-conditioned cancer survivors during the early survivorship phase: the PEACH trial

Broderick, J. M. ; Guinan, E. ; Kennedy, M. J. ; Hollywood, D. ; Courneya, K. S. ; Culos-Reed, S. N. ; Bennett, K. ; O’ Donnell, D. M. ; Hussey, J.

Purpose : This study aims to evaluate the feasibility and efficacy of an 8-week supervised exercise program in de-conditioned cancer survivors within 2–6 months of chemotherapy completion. Methods : Participants were randomly assigned to an 8-week, twice-weekly, supervised aerobic exercise training regime (n = 23) or a usual care group (n = 20). Feasibility was assessed by recruitment rate, program adherence and participant feedback. The primary outcome was aerobic fitness assessed by the [...]

Menée par questionnaire auprès de 170 survivants d'un cancer de l'enfance traité entre 1992 et 2007, cette étude américaine analyse leurs modes de vie, leur qualité de vie et leurs souhaits en matière d'éducation à la santé, qu'il s'agisse d'interventions relatives à la nutrition ou à la promotion de l'activité physique

Health-related quality of life, lifestyle behaviors, and intervention preferences of survivors of childhood cancer

Badr, Hoda ; Chandra, Joya ; Paxton, RaheemJ ; Ater, JoannL ; Urbauer, Diana ; Cruz, CodyScott ; Demark-Wahnefried, Wendy

Purpose : Childhood cancer survivors (CCSs) are at increased risk for poor health-related quality of life (HRQOL) and chronic health conditions—both of which can be exacerbated by unhealthy lifestyle behaviors. Developing a clearer understanding of the associations between HRQOL, lifestyle behaviors, and medical and demographic variables (e.g., age/developmental stage at time of diagnosis) is an important step toward developing more targeted behavioral interventions for this population. Method [...]

Menée par questionnaire auprès de 178 patients atteints de différents types de tumeurs, cette étude espagnole analyse la satisfaction des patients vis-à-vis des soins hospitaliers de jour ainsi que la qualité de vie associée

Determinants of patient satisfaction with care in a Spanish oncology Day Hospital and its relationship with quality of life

Arraras, Juan Ignacio ; Illarramendi, Jose Juan ; Viudez, Antonio ; Ibáñez, Berta ; Lecumberri, Maria Jose ; de la Cruz, Susana ; Hernandez, Berta ; Zarandona, Uxue ; Cambra, Koldo ; Martinez, Maite ; Salgado, Esteban ; Lainez, Nuria ; Vera, Ruth

Objective : This study evaluates satisfaction with care (SC) in cancer patients treated at a Spanish day hospital to identify SC determinants and assess the relationship between SC and quality of life. Methods : One hundred seventy-six patients with different tumour sites and disease stages completed the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), the Cancer Outpatient Satisfaction with Care questionnaire for chemotherapy [...]

Menée au Canada auprès d'enfants âgés de moins de 18 ans, cette étude de cohorte rétrospective analyse la prévalence et les facteurs de risque d'infections chez des patients pédiatriques atteints d'une leucémie aiguë promyélocytaire

Infections in pediatric acute promyelocytic leukemia: from the canadian infections in acute myeloid leukemia research group

Cellot, Sonia ; Johnston, Donna ; Dix, David ; Ethier, Marie-Chantal ; Gillmeister, Biljana ; Mitchell, David ; Yanofsky, Rochelle ; Lewis, Victor ; Portwine, Carol ; Price, Victoria ; Zelcer, Shayna ; Silva, Mariana ; Bowes, Lynette ; Michon, Bruno ; Stobart, Kent ; Brossard, Josee ; Beyene, Joseph ; Sung, Lillian

BACKGROUND:It is not known whether children with acute promyelocytic leukemia (APL) have an infection risk similar to non- APL acute myeloid leukemia. The objective was to describe infectious risk in children with newly diagnosed APL and to describe factors associated with these infections. METHODS:We conducted a retrospective, population-based cohort study that included children <= 18 years of age with de novo APL treated at 15 Canadian centers. Thirty-three children with APL were included; [...]

Mené en Australie auprès de 108 patients atteints d'un cancer du poumon inopérable ou d'un cancer de la plèvre (mésothéliome inclus), cet essai randomisé évalue l'efficacité d'un programme multidisciplinaire de soins de suppport basé sur la prise en charge systématique des besoins psychosociaux

A tailored, supportive care intervention using systematic assessment designed for people with inoperable lung cancer: a randomised controlled trial

Schofield, Penelope ; Ugalde, Anna ; Gough, Karla ; Reece, John ; Krishnasamy, Meinir ; Carey, Mariko ; Ball, David ; Aranda, Sanchia

Objective : People with inoperable lung cancer experience higher levels of distress, more unmet needs and symptoms than other cancer patients. There is an urgent need to test innovative approaches to improve psychosocial and symptom outcomes in this group. This study tested the hypothesis that a tailored, multidisciplinary supportive care programme based on systematic needs assessment would reduce perceived unmet needs and distress and improve quality of life. Methods : A randomised controlled [...]

Menée en Australie par questionnaire auprès de 638 participants, cette étude analyse les facteurs associés à l'adhésion aux recommandations nationales relatives à la pratique d'une activité physique chez les patients atteints d'un cancer de la prostate

Factors associated with adherence to physical activity guidelines in patients with prostate cancer

Chipperfield, Kelly ; Fletcher, Jane ; Millar, Jeremy ; Brooker, Joanne ; Smith, Robin ; Frydenberg, Mark ; Oh, Tracy ; Burney, Sue

Objective : This study aimed to estimate the proportion of patients with prostate cancer (PCa) meeting the National Physical Activity Guidelines of Australia (NPAGA) and determine sociodemographic and medical factors associated with meeting these guidelines. Secondary aims included examining physical activity (PA) levels by treatment type and domain (leisure, work, transport and domestic) and establishing a predictive model of the likelihood that men with PCa would meet NPAGA. Methods : A [...]

A partir de données des registres chinois des cancers portant sur la période 2004-2005, cette étude analyse l'association entre le rayonnement solaire UV-B et la survie des patients atteints de cancer

Relationship between cancer survival and ambient ultraviolet B irradiance in China

Chen, Wanqing ; Armstrong, BruceK ; Rahman, Bayzidur ; Zheng, Rongshou ; Zhang, Siwei ; Clements, Mark

Background : Ecological studies in predominantly European populations have reported higher cancer survival in areas of higher solar ultraviolet (UV) B irradiation, perhaps due to a cancer protective effect of vitamin D synthesized photochemically in the skin. Such studies have not been done in developing countries, perhaps because of lack of cancer registries that can do outcome follow-up. One minus the mortality-to-incidence ratio (1−MIR), however, can be used as a measure of survival, and MIR [...]

Menée auprès de 4 806 survivants d'une leucémie pédiatrique (durée médiane de suivi : 14,5 ans), cette étude américaine analyse le risque de second cancer, notamment lié aux thérapies

Risk of subsequent malignancies in survivors of childhood leukemia

Perkins, StephanieM ; DeWees, Todd ; Shinohara, EricT ; Reddy, MythriM ; Frangoul, Haydar

Purpose : The diagnosis of childhood leukemia now carries a much improved overall survival. With this knowledge comes concern for late effects of therapy, especially the risk of secondary malignancy. Methods : Patients diagnosed with AML or ALL between the ages of 0 and 18 years who survived at least 5 years after diagnosis were included in analysis. Cumulative incidence of subsequent malignancy at 30 years was calculated. To compare incidence of subsequent malignancies with rates of the US [...]

Cette étude présente l'évolution de l'incidence du cancer du col de l'utérus dans 38 pays, notamment en fonction de l'existence d'un dépistage organisé et d'une vaccination contre le papillomavirus humain

Worldwide trends in cervical cancer incidence: Impact of screening against changes in disease risk factors

Vaccarella, Salvatore ; Lortet-Tieulent, Joannie ; Plummer, Martyn ; Franceschi, Silvia ; Bray, Freddie

Cervical cancer trends in a given country mainly depend on the existence of effective screening programmes and time changes in disease risk factors, notably exposure to human papillomavirus (HPV). Screening primarily influences variations by period of diagnosis, whereas changes in risk factors chiefly manifest themselves as variations in risk across successive birth cohorts of women. We assessed trends in cervical cancer across 38 countries in five continents, age group 30–74years, using [...]

A partir des données des registres américains des cancers incluant 7 410 patients atteints d'une tumeur superficielle de la vessie de haut grade, cette étude en population analyse le taux de récidive et le taux de mortalité

Recurrence of high-risk bladder cancer: A population-based analysis

Chamie, Karim ; Litwin, Mark S. ; Bassett, Jeffrey C. ; Daskivich, Timothy J. ; Lai, Julie ; Hanley, Jan M. ; Konety, Badrinath R. ; Saigal, Christopher S. ; the Urologic Diseases in America, Project

BACKGROUND Patients with bladder cancer are apt to develop multiple recurrences that require intervention. The recurrence, progression, and bladder cancer–related mortality rates were examined in a cohort of individuals with high-grade non–muscle-invasive bladder cancer. METHODS Using linked Surveillance, Epidemiology, and End Results (SEER)-Medicare data, subjects were identified who had a diagnosis of high-grade, non–muscle-invasive disease in 1992 to 2002 and who were followed until 2007. [...]

A partir d'une revue de la littérature publiée en 2012, cette étude fait le point sur les psychothérapies destinées à réduire la douleur des patients atteints de cancer

Psychological interventions to reduce pain in patients with cancer

Lossignol, Dominique A.F.

Purpose of review: To review relevant studies about psychological interventions among patients with cancer pain. Recent findings: We used MEDLINE as a source of studies on psychological interventions between January 2012 and December 2012. Most studies were randomized, but there was no homogeneity in terms of psychological intervention types or pain evaluation. Summary: Not all studies with psychological interventions measured pain as a primary outcome; pain was measured inconsistently across [...]

Menée auprès de 283 survivants à long terme (plus de 5 ans) d'un cancer colorectal et ayant subi une stomie, cette étude américaine analyse leur bien-être spirituel et psychologique

Spiritual well-being in long-term colorectal cancer survivors with ostomies

Bulkley, Joanna ; McMullen, Carmit K. ; Hornbrook, Mark C. ; Grant, Marcia ; Altschuler, Andrea ; Wendel, Christopher S. ; Krouse, Robert S.

Objective : Spiritual well-being (SpWB) is integral to health-related quality of life. The challenges of colorectal cancer (CRC) and subsequent bodily changes can affect SpWB. We analyzed the SpWB of CRC survivors with ostomies. Methods : Two-hundred-eighty-three long-term (≥5 years) CRC survivors with permanent ostomies completed the modified City of Hope Quality of Life-Ostomy (mCOH-QOL-O) questionnaire. An open-ended question elicited respondents' greatest challenge in living with an ostomy. [...]

Menée auprès de 286 patients atteints de cancer, cette étude analyse la faisabilité d'une méthode d'auto-déclaration par internet des toxicités symptomatiques de la chimiothérapie constatées à leur domicile

Feasibility of Long-Term Patient Self-Reporting of Toxicities From Home via the Internet During Routine Chemotherapy

Judson, Timothy J. ; Bennett, Antonia V. ; Rogak, Lauren J. ; Sit, Laura ; Barz, Allison ; Kris, Mark G. ; Hudis, Clifford A. ; Scher, Howard I. ; Sabattini, Paul ; Schrag, Deborah ; Basch, Ethan

Purpose : Patient-reported outcomes are increasingly used in routine outpatient cancer care to guide clinical decisions and enhance communication. Prior evidence suggests good patient compliance with reporting at scheduled clinic visits, but there is limited evidence about compliance with long-term longitudinal reporting between visits. Patients and Methods : Patients receiving chemotherapy for lung, gynecologic, genitourinary, or breast cancer at a tertiary cancer center, with access to a home [...]

A partir des données des Etats de Californie et de New-York portant sur 8 798 bénéficiaires de la couverture sociale Medicaid et de 43 912 bénéficiaires de la couverture sociale Medicare, tous patients atteints d'un cancer du poumon de stade IV, cette étude analyse et compare, pour les deux groupes, l'utilisation des soins hospitaliers, le recours aux soins palliatifs et le lieu du décès

Underuse of Hospice Care by Medicaid-Insured Patients With Stage IV Lung Cancer in New York and California

Mack, Jennifer W. ; Chen, Kun ; Boscoe, Francis P. ; Gesten, Foster C. ; Roohan, Patrick J. ; Weeks, Jane C. ; Schymura, Maria J. ; Schrag, Deborah

Purpose : Medicare patients with advanced cancer have low rates of hospice use. We sought to evaluate hospice use among patients in Medicaid, which insures younger and indigent patients, relative to those in Medicare. Patients And methods : Using linked patient-level data from California (CA) and New York (NY) state cancer registries, state Medicaid programs, NY Medicare, and CA Surveillance, Epidemiology, and End Results–Medicare data, we identified 4,797 CA Medicaid patients and 4,001 NY [...]

Menée au Royaume-Uni, cette étude analyse l'efficacité d'une mammographie de dépistage pour les femmes âgées de 35 à 39 ans à risque familial élevé de cancer du sein

Mammographic surveillance in women aged 35–39 at enhanced familial risk of breast cancer (FH02)

Evans, D. G. ; Thomas, S. ; Caunt, J. ; Roberts, L. ; Howell, A. ; Wilson, M. ; Fox, R. ; Sibbering, D. M. ; Moss, S. ; Wallis, M. G. ; Eccles, D. M. ; Duffy, S.

Although there have been encouraging recent studies showing a potential benefit from annual mammography in women aged 40–49 years of age with an elevated breast cancer risk due to family history there is little evidence of efficacy in women aged <40 years of age. A prospective study (FH02) has been developed to assess the efficacy of mammography screening in women aged 35–39 years of age with a lifetime breast cancer risk of ≥17 % who are not receiving MRI screening. Retrospective analyses from [...]

Menée à New York auprès de 271 patients originaires d'Amérique latine, économiquement défavorisés et atteints de cancer, cette étude analyse leur manque de connaissances en matière de cancer et leurs besoins en information de santé

Cancer Stage Knowledge and Desire for Information: Mismatch in Latino Cancer Patients?

Costas-Muniz, Rosario ; Sen, Rohini ; Leng, Jennifer ; Aragones, Abraham ; Ramirez, Julia ; Gany, Francesca

Having more health knowledge has a crucial and positive impact on cancer outcomes. Patients’ cancer knowledge influences their ability to participate actively in decision-making processes for medical care and in treatment choices. The purpose of this study was to determine the demographic and medical correlates of lack of cancer stage knowledge and desire for information among Latino cancer patients. The sample included 271 underserved Latino cancer patients recruited from four cancer clinics [...]

Menée par questionnaire auprès de participants âgés de 50 à 75 ans, cette étude américaine analyse et compare, chez les fumeurs et les non-fumeurs, leurs perceptions du risque de cancer colorectal et leurs comportements vis-à-vis du dépistage de ce cancer

Perceptions of Risk Factors for Colorectal Cancer and Colorectal Cancer Risk-Related Behaviors Among Current, ex-, and Nonsmokers

Messina, CatherineR ; Lane, DorothyS ; Anderson, JosephC

Smoking significantly increases risk for colorectal cancer (CRC). We examined smokers’ and nonsmokers’ perceptions of behavioral factors for the increased risk of CRC and evaluated how these related to CRC screening. Self-reported questionnaire data were obtained from a random, average CRC risk sample of women and men (aged 50–75 years) during 2004. Smokers less frequently reported recent CRC screening than nonsmokers (p = 0.03). Smokers not adherent to screening less frequently agreed that [...]

Menée dans l'Etat de New-York auprès de 484 participants, principalement des étudiants, cette étude analyse l'efficacité d'un programme d'éducation à la santé relatif au cancer du sein

The Effectiveness of a Community-Based Breast Cancer Education Intervention in the New York State Capital Region

Zeinomar, Nur ; Moslehi, Roxana

We determined the effectiveness of a community-based breast cancer education intervention among understudied populations in the New York State (NYS) Capital Region by assessing and comparing baseline and post-education breast cancer knowledge. Participants included 417 students recruited from five colleges/universities and 67 women from four community group organizations. Baseline and post-education knowledge was assessed via self-administered mostly multiple-choice questionnaires. An [...]

Cette étude présente des recommandations sur la mise en place précoce de soins palliatifs pour des patients atteints d'un cancer de stade avancé

Early palliative care for patients with advanced cancer: how to make it work?

Gaertner, Jan ; Weingärtner, Vera ; Wolf, Jürgen ; Voltz, Raymon

Purpose of review: As the benefit of early palliative care for the quality of life of patients with advanced cancer is currently receiving widespread recognition, cancer specialists increasingly inquire about the practical implications of this concept. This publication presents the available information about how to provide early palliative care for patients with advanced cancer. Recent findings: Oncologists and other cancer specialists provide general palliative care from the time of diagnosis [...]

Menée à TaÏwan à partir de données portant sur 203 642 patients adultes décédés d'un cancer entre 2001 et 2006, cette étude analyse les facteurs démographiques, médicaux et thérapeutiques associés à des soins de fin de vie classés en fonction de leur agressivité

Latent class analysis identifies three subtypes of aggressive end-of-life care: A population-based study in Taiwan

Chen, Mei-Ling ; Chen, Yun-Yi ; Tang, Siew Tzuh

The aggressiveness of end-of-life (EOL) cancer care has often been analysed by the occurrence of several indicators, separately or aggregately. Whether aggressive EOL cancer care has different subtypes is unknown. This study sought to identify distinct subtypes of aggressive EOL care based on usage patterns of aggressive EOL-care indicators and to explore demographic, disease and treatment factors associated with the identified subtypes. This retrospective study linked data from 2001 to 2006 [...]