Mené auprès de 197 patientes atteintes d'un cancer du sein, cet essai randomisé analyse l'efficacité d'une intervention d'acupuncture pratiquée par soi-même, après des séances de formation chez un thérapeute, pour réduire la fatigue liée au cancer

A randomized, controlled trial of acupuncture self-needling as maintenance therapy for cancer-related fatigue after therapist-delivered acupuncture

Molassiotis, A. ; Bardy, J. ; Finnegan-John, J. ; Mackereth, P. ; Ryder, W. D. ; Filshie, J. ; Ream, E. ; Eaton, D. ; Richardson, A.

Background : Maintenance acupuncture is advocated by clinicians after successful clinic-based acupuncture. We aimed to assess the effectiveness of maintenance acupuncture in the management of cancer-related fatigue (CRF); treatment delivered by therapists or self-acupuncture/self-needling was compared with no maintenance treatment. Methods : Breast cancer patients who participated in a randomized trial of acupuncture for CRF management (reported elsewhere) were re-randomized to receive an [...]

A partir des données du registre suédois des cancers, cette étude analyse le taux de naissances chez 42 691 survivantes d'un cancer

Birth rates among female cancer survivors

Hartman, Mikael ; Liu, Jenny ; Czene, Kamila ; Miao, Hui ; Chia, Kee Seng ; Salim, Agus ; Verkooijen, Helena M.

BACKGROUND: More women of fertile age are long-term survivors of cancer. However, population-based data on birth rates of female cancer survivors are rare. METHODS: A total of 42,691 women ≤ 45 years with a history of cancer were identified from the Swedish Multi-Generation Register and the Swedish Cancer Register, for whom relative birth rates were calculated as compared to the background population, ie, standardized birth ratios (SBRs). Independent factors associated with reduced birth rates [...]

Menée par enquête auprès de 268 participants australiens et de 169 participants canadiens, cette étude transversale compare, dans ces deux groupes, les besoins non satisfaits en termes de soins de support de survivants d'un cancer hématologique

Unmet needs of Australian and Canadian haematological cancer survivors: a cross-sectional international comparative study

Hall, Alix ; Campbell, H. Sharon ; Sanson-Fisher, Rob ; Lynagh, Marita ; D'Este, Catherine ; Burkhalter, Robin ; Carey, Mariko

Objective : Few population-based studies have assessed the needs of haematological cancer survivors or conducted international comparisons. We aimed to assess and compare the unmet needs of Australian and Canadian haematological cancer survivors. Methods : Two cross-sectional datasets were analysed. Survivors were recruited from population-based cancer registries and sent a self-report survey containing the Survivors Unmet Needs Survey. Australians were aged 18–80years at the time of study and [...]

A partir des données des registres américains des cancers (1 579 310 cas) sur la période 1992-2005, cette étude évalue le nombre d'années de vie perdues pour six types de cancers (poumon, côlon-rectum, foie, sein, col de l'utérus, prostate) dont certaines formes sont potentiellement évitables

Expected years of life lost for six potentially preventable cancers in the United States

Liu, Pang-Hsiang ; Wang, Jung-Der ; Keating, Nancy L.

Objective : This study aimed to quantify the reduced life expectancy for six types of potentially preventable cancer in the United States. Methods : A total of 1,579,310 patients diagnosed with cancers of the lung, colon and rectum, liver, breast, cervix, or prostate in 1992-2005 were identified from the Surveillance, Epidemiology, and End Results registries. The lifetime survival functions for the cancer cohort and age-/sex-matched reference population were generated using a semiparametric [...]

Menée au Royaume-Uni auprès de 46 656 participants âgés de plus de 50 ans, cette étude de cohorte analyse l'association entre des douleurs et des troubles musculosquelettiques et le risque de cancer de la prostate, du sein, du poumon ou du côlon-rectum

Incidence of prostate, breast, lung and colorectal cancer following new consultation for musculoskeletal pain: A cohort study among UK primary care patients

Jordan, Kelvin P. ; Hayward, Richard A. ; Blagojevic-Bucknall, Milisa ; Croft, Peter

Musculoskeletal pain has been linked with subsequent cancer. The objective was to investigate associations between pain sites and specific cancers, and investigate the hypothesis that musculoskeletal pain is an early marker, rather than cause, of cancer. This was a cohort study in the General Practice Research Database. From a cohort of 46,656 people aged ≥50 years with a recorded musculoskeletal problem in 1996 but not during the previous 2 years, patients with a new consultation for back, [...]

Menée auprès de 1 686 patients pédiatriques atteints de leucémie myéloïde aiguë, cette étude américaine analyse l'évolution de la mortalité en fonction de deux protocoles d'induction, l'un par dexaméthasone, cytarabine, thioguanine, étoposide et rubidomycine, l'autre par cytarabine, daunomycine et étoposide, sur la période 1999-2010

Induction mortality and resource utilization in children treated for acute myeloid leukemia at free-standing pediatric hospitals in the United States

Kavcic, Marko ; Fisher, Brian T. ; Li, Yimei ; Seif, Alix E. ; Torp, Kari ; Walker, Dana M. ; Huang, Yuan-Shung ; Lee, Grace E. ; Tasian, Sarah K. ; Vujkovic, Marijana ; Bagatell, Rochelle ; Aplenc, Richard

BACKGROUND: Clinical trials in pediatric acute myeloid leukemia (AML) determine induction regimen standards. However, these studies lack the data necessary to evaluate mortality trends over time and differences in resource utilization between induction regimens. Moreover, these trials likely underreport the clinical toxicities experienced by patients. METHODS: The Pediatric Health Information System database was used to identify children treated for presumed de novo AML between 1999 and 2010. [...]

A partir des données de l'Organisation mondiale de la santé, cette étude analyse l'évolution de la mortalité par lymphome hodgkinien en Amérique du nord, au Canada et dans 12 pays d'Amérique latine, sur la période 1997-2008

Hodgkin's lymphoma mortality in the Americas, 1997–2008: Achievements and persistent inadequacies

Chatenoud, Liliane ; Bertuccio, Paola ; Bosetti, Cristina ; Rodriguez, Teresa ; Levi, Fabio ; Negri, Eva ; Vecchia, Carlo La

Although therapeutic advancements have made Hodgkin's lymphoma (HL) a largely curable disease, trends in HL mortality have been variable across countries. To provide updated information on HL mortality in the Americas, overall and 20–44 years age-standardized (world population) mortality rates from HL were derived for the 12 Latin American countries providing valid data to the World Health Organization database and with more than two million of inhabitants. For comparative purpose, data for the [...]

A partir des données du registre danois des cancers, cette étude de cohorte en population incluant 6 626 participantes évalue l'association entre l'utilisation de médicaments ß-bloquants et la mortalité des patientes atteintes d'un cancer de l'ovaire

Use of ß-blockers and mortality following ovarian cancer diagnosis: a population-based cohort study

Johannesdottir, Sigrun ; Schmidt, Morten ; Phillips, Gary ; Glaser, Ronald ; Yang, Eric ; Blumenfeld, Michael ; Lemeshow, Stanley

BACKGROUND:Experimental data suggest that catecholamine hormones are involved in stimulating the aggressiveness of ovarian cancer, but few population-based studies have examined this association. We therefore conducted a population-based cohort study to examine whether ß-blockers affect mortality following ovarian cancer diagnosis. METHODS:We used the Danish Cancer Registry to identify all patients diagnosed with ovarian cancer in northern Denmark between 1999 and 2010 (n=6,626). Data on [...]

A partir des données des registres américains des cancers portant sur la période 1979-2008, cette étude de cohorte en population incluant 64 673 participants analyse l'évolution de la prévalence d'un second cancer primitif synchrone chez des patients atteints d'un carcinome épidermoïde de la tête et du cou

Synchronous cancers in patients with head and neck cancer

Jain, Kunal S. ; Sikora, Andrew G. ; Baxi, Shrujal S. ; Morris, Luc G. T.

BACKGROUND: Second primary malignancies (SPMs) are the leading cause of death in survivors of head and neck squamous cell carcinoma (HNSCC). Synchronous SPMs are of significant clinical interest because they potentially can be identified by screening procedures at the time of diagnosis of the index cancer. Recently, human papillomavirus (HPV) has emerged as a distinct risk factor for oropharyngeal head and neck squamous cell carcinoma (HNSCC), differing from classic tobacco/alcohol-associated [...]

Menée par questionnaire auprès de 753 patients atteints de cancer et traités à l'extérieur de l'hôpital, cette étude japonaise analyse la détresse associée aux changements d'apparence physique chez des patients recevant une chimiothérapie

Quantitative assessment of appearance changes and related distress in cancer patients

Nozawa, Keiko ; Shimizu, Chikako ; Kakimoto, Minako ; Mizota, Yuri ; Yamamoto, Seiichiro ; Takahashi, Yumiko ; Ito, Atsuko ; Izumi, Hideko ; Fujiwara, Yasuhiro

Objectives : This study examined both the frequency of appearance-related symptoms and distress resulting from these symptoms in cancer patients receiving chemotherapy. Methods : Self-report questionnaires were distributed to 753 outpatients receiving 4 weeks of treatment at an outpatient chemotherapy center. Valid responses were returned by 638 patients (response rate, 84.7%). Participants were questioned about 57 appearance-related symptoms (AS) and 23 non-appearance-related physical symptoms [...]

Cette étude américaine présente et analyse l'efficacité d'un outil élaboré dans un centre de lutte contre le cancer permettant de détecter rapidement les symptômes de détresse de patients atteints de cancer

The James Supportive Care Screening: integrating science and practice to meet the NCCN guidelines for distress management at a Comprehensive Cancer Center

Gregorio, Sharla Wells-Di ; Porensky, Emily K. ; Minotti, Matthew ; Brown, Susan ; Snapp, Janet ; Taylor, Robert M. ; Adolph, Michael D. ; Everett, Sherman ; Lowther, Kenneth ; Callahan, Kelly ; Streva, Devita ; Heinke, Vicki ; Leno, Debra ; Flower, Courtney ; McVey, Anne ; Andersen, Barbara Lee

Background : Selecting a measure for oncology distress screening can be challenging. The measure must be brief, but comprehensive, capturing patients' most distressing concerns. The measure must provide meaningful coverage of multiple domains, assess symptom and problem-related distress, and ideally be suited for both clinical and research purposes. Methods : From March 2006 to August 2012, the James Supportive Care Screening (SCS) was developed and validated in three phases including content [...]

Menée en Italie auprès de 1 108 patients atteints de cancer et traités à l'extérieur de l'hôpital, cette étude analyse l'efficacité d'un outil de mesure de leurs symptômes de détresse

Screening for distress in cancer patients

Grassi, Luigi ; Johansen, Christoffer ; Annunziata, Maria Antonietta ; Capovilla, Eleonora ; Costantini, Anna ; Gritti, Paolo ; Torta, Riccardo ; Bellani, Marco ; on behalf of the Italian Society of Psycho-Oncology Distress Thermometer Study, Group

BACKGROUND: Routine screening for distress is internationally recommended as a necessary standard for good cancer care, given its high prevalence and negative consequences on quality of life. The objective of the current study was to contribute to the Italian validation of the Distress Thermometer (DT) to determine whether the single item DT compared favorably with referent criterion measures. METHODS: In total, 1108 outpatients with cancer were recruited from 38 representative oncology centers [...]

A partir de travaux menés au sein du National Cancer Institute, cette étude américaine décrit l'élaboration d'un outil permettant de s'assurer de la qualité des soins psychosociaux destinés aux survivants d'un cancer et de veiller à leur mise en œuvre efficiente dans les centres de lutte contre le cancer

The cancer psychosocial care matrix: a community-derived evaluative tool for designing quality psychosocial cancer care delivery

Forsythe, Laura P. ; Rowland, Julia H. ; Padgett, Lynne ; Blaseg, Karyl ; Siegel, Scott D. ; Dingman, Chad M. ; Gillis, Theresa A.

Objective : Although the Institute of Medicine provided a vision for effective psychosocial care for cancer survivors, limited guidance exists regarding the essential components of comprehensive care or progressive steps for implementing each component. This paper describes the development of a unique tool for assessing capacity to provide quality psychosocial care to cancer survivors and the results of the first implementation of this tool in community settings. Methods : The psychosocial [...]

Menée par téléphone auprès de 1 139 participantes, cette étude américaine analyse les disparités ethniques dans les manifestations de stress post-traumatique à la suite d'un diagnostic de cancer du sein localisé

Racial Disparities in Posttraumatic Stress After Diagnosis of Localized Breast Cancer: The BQUAL Study

Vin-Raviv, Neomi ; Clarke Hillyer, Grace ; Hershman, Dawn L. ; Galea, Sandro ; Leoce, Nicole ; Bovbjerg, Dana H. ; Kushi, Lawrence H. ; Kroenke, Candyce ; Lamerato, Lois ; Ambrosone, Christine B. ; Valdimorsdottir, Heidis ; Jandorf, Lina ; Mandelblatt, Jeanne S. ; Tsai, Wei-Yann ; Neugut, Alfred I.

Background Little is known about the development of posttraumatic stress disorder (PTSD) over time among women diagnosed with breast cancer. This study examines changes in PTSD symptoms in the first 6 months after diagnosis and assesses racial/ethnic differences in PTSD symptomatology over time. Methods We recruited women with newly diagnosed breast cancer, stages I to III, from three sites in the United States. Three telephone interviews were conducted: baseline at about 2 to 3 months after [...]

Mené aux Pays-Bas auprès de 205 participants, cet essai randomisé analyse les effets d'une intervention psychosociale faite par une infirmière sur les symptômes de dépression de patients atteints d'un cancer de la tête et du cou, un an après le diagnostic

One-Year Effect of a Nurse-Led Psychosocial Intervention on Depressive Symptoms in Patients With Head and Neck Cancer: A Randomized Controlled Trial

van der Meulen, Ingeborg C. ; May, Anne M. ; Ros, Wynand J.G. ; Oosterom, Miriam ; Hordijk, Gert-Jan ; Koole, Ron ; de Leeuw, J. Rob. J.

Background : Many patients with head and neck cancer (HNC) experience depressive symptoms after treatment. This randomized controlled trial investigated the effects of a psychosocial nurse counseling and after intervention (NUCAI) versus usual care on the depressive and HNC-related physical symptoms of patients with HNC at 1 year after diagnosis. Methods : A total of 205 patients with HNC were randomly assigned to either intervention (n = 103) or usual care (n = 102), with stratification for [...]

Menée en Espagne auprès de 795 participants, cette étude transversale analyse les facteurs associés à la durée de la période séparant le début des symptômes et le moment du diagnostic ou du traitement d'un cancer colorectal

Factors related with symptom duration until diagnosis and treatment of symptomatic colorectal cancer

Esteva, Magdalena ; Leiva, Alfonso ; Ramos, Maria ; Pita-Fernandez, Salvador ; Gonzalez-Lujan, Luis ; Casamitjana, Montse ; Sanchez, Maria ; Pertega-Diaz, Sonia ; Ruiz, Amador ; Gonzalez-Santamaria, Paloma ; Martin-Rabadan, Maria ; Costa-Alcaraz, Ana ; Espi, Alejandro ; Macià, Francesc ; Segura, Josep ; Lafita, Sergio ; Arnal-Monreal, Francisco ; Amengual, Isabel ; Bosca-Watts, Marta ; Hospital, Angels ; Manzano, Hermini ; Magallon, Rosa

BACKGROUND:Colorectal cancer (CRC) survival depends mostly on stage at the time of diagnosis. However, symptom duration at diagnosis or treatment have also been considered as predictors of stage and survival. This study was designed to: 1) establish the distinct time-symptom duration intervals; 2) identify factors associated with symptom duration until diagnosis and treatment. METHODS:This is a cross-sectional study of all incident cases of symptomatic CRC during 2006--2009 (795 incident cases) [...]

Cet article britannique plaide pour le ré-équilibrage des politiques nationales de lutte contre le cancer axées autour de la personne et prenant davantage en compte l'expérience personnelle et psychosociale de l'individu

What really matters in cancer?: Putting people back into the heart of cancer policy

Purushotham, Arnie ; Cornwell, Jocelyn ; Burton, Catherine ; Stewart, Derek ; Sullivan, Richard

Twenty-first century cancer is framed by the biomedical revolution. The cancer patient today enters a world dominated by the success and failures of biomedical science from gene to statistic. By any measure, bibliometric, financial, media profile or simply the lingua franca of everyday discourse about cancer, biomedicine occupies the majority of the cultural discourse around cancer. Yet the reality is that patients are people who are diagnosed, treated, survive and die with cancer in a world [...]

A partir dune revue systématique de la littérature publiée entre 1987 et 2012, cette étude fait le point sur les facteurs de risque, les caractéristiques biologiques, le diagnostic, le pronostic et les traitements du cancer du sein chez l'homme et ainsi que les problématiques médicales et psychosociales rencontrées par les survivants

Male breast cancer: risk factors, biology, diagnosis, treatment, and survivorship

Ruddy, K. J. ; Winer, E. P.

Background : The causes, optimal treatments, and medical/psychosocial sequelae of breast cancer in men are poorly understood. Design : A systematic review of the English language literature was conducted to identify studies relevant to male breast cancer between 1987 and 2012 and including at least 20 patients. Searches were carried out on PubMed using the title terms ‘male breast cancer’ or ‘male breast carcinoma’. Results : Relevant published data regarding risk factors, biological [...]