A partir d'une revue de la littérature, cette étude met à jour les recommandations COG-LTFU relatives au suivi des survivantes d'un cancer de l'enfance et notamment à la détection et prise en charge de complications liées à leur fertilité et induites par les traitements

Female Reproductive Health After Childhood, Adolescent, and Young Adult Cancers: Guidelines for the Assessment and Management of Female Reproductive Complications

Metzger, Monika L. ; Meacham, Lillian R. ; Patterson, Briana ; Casillas, Jacqueline S. ; Constine, Louis S. ; Hijiya, Nobuko ; Kenney, Lisa B. ; Leonard, Marcia ; Lockart, Barbara A. ; Likes, Wendy ; Green, Daniel M.

Purpose As more young female patients with cancer survive their primary disease, concerns about reproductive health related to primary therapy gain relevance. Cancer therapy can often affect reproductive organs, leading to impaired pubertal development, hormonal regulation, fertility, and sexual function, affecting quality of life. Methods The Children’s Oncology Group Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancer (COG-LTFU Guidelines) are [...]

A partir d'une revue de la littérature, cette étude fait le point sur l'efficacité et l'utilisation de l'acupuncture pour soulager la douleur et les symptômes associés au cancer

Acupuncture for Cancer Pain and Related Symptoms

Lu, Weidong ; Rosenthal, David S

Cancer pain is one of most prevalent symptoms in patients with cancer. Acupuncture and related techniques have been suggested for the management of cancer pain. The National Comprehensive Cancer Network guidelines for adult cancer pain recommends acupuncture, as one of several integrative interventions, in conjunction with pharmacologic intervention as needed. This review presents the latest available evidence regarding the use of acupuncture for cancer pain. It also provides “actionable” [...]

Menée par questionnaire sur la période 2008-2011 auprès de 139 patients, cette étude prospective coréenne analyse la qualité de vie de patients âgés et atteints d'un cancer du poumon non à petites cellules traité par chimiothérapie adjuvante

Prospective analysis of quality of life in elderly patients treated with adjuvant chemotherapy for non-small-cell lung cancer

Park, S. ; Kim, I. R. ; Baek, K. K. ; Lee, S. J. ; Chang, W. J. ; Maeng, C. H. ; Hong, J. Y. ; Choi, M. K. ; Kim, Y. S. ; Sun, J. M. ; Ahn, J. S. ; Park, K. ; Jo, J. ; Jung, S. H. ; Ahn, M.J.

Background Given the more comorbidities with a decline in physiologic reserve, it can be challenging to make appropriate treatment decisions in the elderly. Patients and methods Here, we prospectively evaluated and compared the health-related quality of life (HRQOL) of patients aged ≥65 with aged <65 who were treated with a postoperative chemotherapy for completely resected stage Ib, II or IIIa non-small-cell lung cancer (NSCLC). Either four cycles of paclitaxel (Taxol)–carboplatin (PC) or [...]

Cette étude (59 cas et 118 témoins) évalue les risques associés à une auto-greffe de masse adipeuse pour améliorer la qualité d'une reconstruction mammaire chez des patientes atteintes de néoplasies mammaires intraépithéliales

Evaluation of fat grafting safety in patients with intra epithelial neoplasia: a matched-cohort study

Petit, J.Y. ; Rietjens, M. ; Botteri, E. ; Rotmensz, N. ; Bertolini, F. ; Curigliano, G. ; Rey, P. ; Garusi, C. ; De Lorenzi, F. ; Martella, S. ; Manconi, A. ; Barbieri, B. ; Veronesi, P. ; Intra, M. ; Brambullo, T. ; Gottardi, A. ; Sommario, M. ; Lomeo, G. ; Iera, M. ; Giovinazzo, V. ; Lohsiriwat, V.

Background Fat grafting is widely carried out in breast cancer patients to improve quality in breast reconstruction. Recently, in vitro and animal studies have questioned the role of adipose tissues in cancer development. Designs Matched-cohort study. We analysed: (i) 59 intraepithelial neoplasia patients who had undergone lipofilling, with no recurrence between primary surgery and lipofilling. (ii) A control group of 118 matched patients (two controls per lipofilling patient) with the [...]

Cet article de l'American Cancer Society présente les estimations de l'incidence des cancers, de la mortalité, de la survie et des pratiques de dépistage dans la population afro-américaine pour l'année 2013

Cancer statistics for African Americans, 2013

DeSantis, Carol ; Naishadham, Deepa ; Jemal, Ahmedin

In this article, the American Cancer Society estimates the number of new cancer cases and deaths for African Americans and compiles the most recent data on cancer incidence, mortality, survival, and screening prevalence based upon incidence data from the National Cancer Institute, the Centers for Disease Control and Prevention, and the North American Association of Central Cancer Registries and mortality data from the National Center for Health Statistics. It is estimated that 176,620 new cases [...]

Menée sur 75 patients traités en France entre 1988 et 2009, cette étude de cohorte rétrospective analyse les conséquences de diverses modalités thérapeutiques (radiothérapie, chirurgie, chimiothérapie néoadjuvante) pour traiter un sarcome d'Ewing localisé au niveau de la colonne vertébrale

Local control and sequelae in localised Ewing tumours of the spine: A French retrospective study

Vogin, Guillaume ; Helfre, Sylvie ; Glorion, Christophe ; Mosseri, Véronique ; Mascard, Eric ; Oberlin, Odile ; Gaspar, Nathalie

To evaluate both local outcome and sequelae of non-metastatic spinal Ewing tumours (EWT). A French cohort of patients 50years with localised spinal EWT treated between 1988 and 2009, was analysed in regard to tumour characteristics (e.g. volume, vertebral compartment, spinal cord compression, paraspinal soft tissue invasion), local treatment modalities (surgery (S) and margin quality, radiotherapy (RT) dose), response to treatment (e.g. histological response to neoadjuvant chemotherapy (CT)), [...]

A partir des données de trois registres français et d'un registre anglais des cancers, cette étude analyse et compare, pour les deux pays, les différences dans la prise en charge d'un cancer colorectal et dans la survie relative à un an

Management of colorectal cancer explains differences in 1-year relative survival between France and England for patients diagnosed 1997-2004

Dejardin, O. ; Rachet, B. ; Morris, E. ; Bouvier, V. ; Jooste, V. ; Haynes, R. ; Coombes, E. G. ; Forman, D. ; Jones, A. P. ; Bouvier, A. M. ; Launoy, G.

Background:Few international population-based studies have provided information on potential determinants of international disparities in cancer survival. This population-based study was undertaken to identify the principal differences in disease characteristics and management that accounted for previously observed poorer survival in English compared with French patients with colorectal cancer. Methods:The study population comprised all cases of colorectal cancer diagnosed between 1997 and 2004 [...]

Menée au Vietnam auprès de 4 500 femmes mariées, cette étude transversale analyse la prévalence d'une infection par le papillomavirus humain de types 16 et 18

Prevalence of cervical infection with HPV type 16 and 18 in Vietnam: implications for vaccine campaign

Vu, Lan ; Bui, Dieu ; Le, Ha

BACKGROUND:The Expanded Program on Immunization currently considers offering Human Papilomavirus vaccine on a routine basis in Vietnam. However, as the current available vaccine can prevent only two types HPV 16 and 18, before implementing a large-scale vaccine campaign we need information about the prevalence of infection with only HPV 16 and 18 in Viet Nam. This study was done in 5 large cities in Vietnam to estimate the prevalence of HPV 16 and/or 18 infections and to explore the [...]

Menée en Allemagne auprès de 1 281 patients pendant un programme de réadaptation et un an après, cette étude prospective analyse les facteurs associés à la peur d'une récidive chez des survivants d'un cancer

Predictors of fear of recurrence in patients one year after cancer rehabilitation: A prospective study

Mehnert, Anja ; Koch, Uwe ; Sundermann, Christin ; Dinkel, Andreas

Background. Fear of cancer recurrence (FCR) or cancer progression is one of the most frequent distressing psychological symptoms in cancer patients. In contrast to anxiety disorders according to the ICD-10 or DSM-IV, FCR describes an emotional response to the real threat of a life-threatening illness. Elevated levels of FCR can become dysfunctional, causing considerable disruption in social functioning, and affect well-being and quality of life (QoL). We examined the prevalence and course of [...]

Menée en Suisse par questionnaire auprès de 407 survivants d'un cancer de l'enfance, âgés de 16 à 19 ans au moment de l'étude, et de 102 témoins, cette étude analyse les facteurs de risque d'une détresse psychologique

Adolescent survivors of childhood cancer: are they vulnerable for psychological distress?

Gianinazzi, Micol E. ; Rueegg, Corina S. ; Wengenroth, Laura ; Bergstraesser, Eva ; Rischewski, Johannes ; Ammann, Roland A. ; Kuehni, Claudia E. ; Michel, Gisela ; for Swiss Pediatric Oncology, Group

Objectives : We aimed to (i) evaluate psychological distress in adolescent survivors of childhood cancer and compare them to siblings and a norm population; (ii) compare the severity of distress of distressed survivors and siblings with that of psychotherapy patients; and (iii) determine risk factors for psychological distress in survivors. Methods We sent a questionnaire to all childhood cancer survivors aged <16 years when diagnosed, who had survived ≥5years and were aged 16–19 years at the [...]

Menée au Canada, cette étude fait le point sur l'accessibilité, la fiabilité et l'utilisation des services de congélation de sperme dans les hôpitaux traitant des patients atteints de cancer

A national study of the provision of oncology sperm banking services among Canadian fertility clinics

Yee, S. ; Buckett, W. ; Campbell, S. ; Yanofsky, R. A. ; Barr, R. D.

The purpose of this study was to survey the current state of oncology sperm banking services provided by fertility clinics across Canada. A total of 78 Canadian fertility facilities were invited to complete a questionnaire related to the availability, accessibility, affordability and utilisation of sperm banking services for cancer patients. The total response rate was 59%, with 20 (69%) in vitro fertilisation clinics and 26 (53%) other fertility centres returning the survey. A total of 24 [...]

Menée au Royaume-Uni à partir de données portant sur 13 035 patients atteints de cancer en 2009-2010, cette étude analyse le délai entre la première visite chez un médecin généraliste et le diagnostic de cancer lors d'une consultation chez un spécialiste

Measures of promptness of cancer diagnosis in primary care: secondary analysis of national audit data on patients with 18 common and rarer cancers

Lyratzopoulos, G. ; Abel, G. A. ; McPhail, S. ; Neal, R. D. ; Rubin, G. P.

Background: Evidence is needed about the promptness of cancer diagnosis and associations between its measures. Methods: We analysed data from the National Audit of Cancer Diagnosis in Primary Care 2009–10 exploring the association between the interval from first symptomatic presentation to specialist referral (the primary care interval, or ‘interval’ hereafter) and the number of pre-referral consultations. Results: Among 13 035 patients with any of 18 different cancers, most (82%) were referred [...]

Menée par entretiens téléphoniques auprès de neuf hommes et onze femmes atteints d'un mélanome à haut risque de récidive, cette étude qualitative australienne analyse les facteurs associés à leur satisfaction vis-à-vis de leur prise en charge

Melanoma survivors at high risk of developing new primary disease: a qualitative examination of the factors that contribute to patient satisfaction with clinical care

McLoone, J. K. ; Watts, K. J. ; Menzies, S. W. ; Barlow-Stewart, K. ; Mann, G. J. ; Kasparian, N. A.

Background Providing ongoing clinical care that adequately addresses patients' medical, psychosocial and information needs is challenging, particularly for patient groups at increased risk of developing life-threatening disease such as malignant melanoma. This study examined a model of clinical care developed by the High Risk Clinic (HRC) of the Sydney Melanoma Diagnostic Centre in relation to patient satisfaction. Methods Semi-structured telephone interviews were conducted and analyzed using [...]

Menée en Ethiopie auprès de 227 patientes atteintes d'un cancer du col de l'utérus et traitées en milieu hospitalier, cette étude transversale analyse le coût médical à charge de la patiente et son impact sur les traitements choisis

Patient side cost and its predictors for cervical cancer in Ethiopia: a cross sectional hospital based study

Hailu, Alemayehu ; Mariam, Damen

BACKGROUND:Cervical cancer is a leading cause of death from cancer among women in low-resource settings, affecting women at a time of life when they are critical to social and economic stability. In addition, the economic burden is important for policy formulation. The aim of this study is to estimate patient side cost and to determine predictors of its variation for the treatment of cervical cancer. METHODS:Analytic cross sectional study involving 227 cervical cancer cases at Tikur Anbessa [...]

Menée par entretiens auprès de 20 patients norvégiens et 10 patients autrichiens, cette étude qualitative analyse les symptômes de la dépression chez des patients atteints d'un cancer incurable

Depressed patients with incurable cancer: Which depressive symptoms do they experience?

Brenne,Elisabeth ; Loge,Jon Håvard ; Kaasa,Stein ; Heitzer,Ellen ; Knudsen,Anne Kari ; Wasteson,Elisabet

Objective: Diagnosing depressive disorders in palliative care is challenging because of the overlap between some depressive symptoms and cancer-related symptoms, such as loss of appetite and fatigue. In order to improve future assessment of depression in palliative care, depressive symptoms experienced by patients receiving pharmacological treatment for depression were assessed and compared to the American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, 4th ed. [...]