A partir d'une revue systématique de la littérature (14 études, total de 2 759 patients), cette étude fait le point sur l'association entre diverses formes de soutien psychosocial et la qualité de vie de patients atteints d'un cancer du poumon

Social support and quality of life among lung cancer patients: a systematic review

Luszczynska, Aleksandra ; Pawlowska, Izabela ; Cieslak, Roman ; Knoll, Nina ; Scholz, Urte

Objective This systematic review analyzed the relationships between social support and quality of life (QOL) indicators among lung cancer patients. In particular, the patterns of relationships between different social support facets and sources (received and perceived support from healthcare professionals, family, and friends) and QOL aspects (emotional, physical symptoms, functional, and social) as well as the global QOL index were investigated. Methods The review yielded 14 original studies [...]

A partir d'une revue systématique de la littérature, cette méta-analyse d'essais randomisés évalue le risque d'accident thrombo-embolique artériel chez des patients atteints d'un cancer traité par cisplatine

Arterial Thromboembolism in Cancer Patients Treated With Cisplatin: A Systematic Review and Meta-analysis

Proverbs-Singh, Tracy ; Chiu, Sophia K. ; Liu, Ziyue ; Seng, Sonia ; Sonpavde, Guru ; Choueiri, Toni K. ; Tsao, Che-kai ; Yu, Menggang ; Hahn, Noah M ; Oh, William K. ; Galsky, Matthew D.

Cisplatin has been associated with an increased risk of arterial thromboembolic events (ATEs). However, because this association is mostly based on case reports and retrospective studies, we conducted a systemic review and meta-analysis of randomized controlled trials evaluating the incidence and risk of ATEs associated with cisplatin. Eligible studies included prospective randomized phase II and III trials evaluating cisplatin-based vs non-cisplatin-based chemotherapy in patients with solid [...]

Cette étude de cohorte japonaise incluant 2 438 participants âgés de 40 à 79 ans évalue l'association entre le niveau de tolérance au glucose et la mortalité par cancer (durée de suivi : 19 ans)

Association Between Glucose Tolerance Level and Cancer Death in a General Japanese Population: The Hisayama Study

Hirakawa, Yoichiro ; Ninomiya, Toshiharu ; Mukai, Naoko ; Doi, Yasufumi ; Hata, Jun ; Fukuhara, Masayo ; Iwase, Masanori ; Kitazono, Takanari ; Kiyohara, Yutaka

The authors examined the associations of glucose tolerance status and fasting and 2-hour postload glucose levels with the risk of cancer death in a 19-year follow-up study of 2,438 Japanese subjects aged 40–79 years who underwent a 75-g oral glucose tolerance test (1988–2007). During follow-up, 229 subjects died of cancer. The risk of cancer death was significantly higher in subjects with fasting plasma glucose levels of ≥5.6 mmol/L or 2-hour postload glucose levels of ≥11.1 mmol/L than in [...]

A partir des données des registres néerlandais des cancers, cette étude analyse l'incidence des cancers du col de l'utérus, de l'œsophage et du colon, ainsi que la survie, dans les populations d'immigrés sur la période 1996-2009

Investigating cervical, oesophageal and colon cancer risk and survival among migrants in The Netherlands

Arnold, Melina ; Josepha Aarts, Mieke ; van der Aa, Maaike ; Visser, Otto ; Willem Coebergh, Jan

Background: Studies on cancer in migrants can shed light on grey areas in cancer aetiology and can help assessing the effectiveness of prevention measures. In this study, we aimed to determine the impact of migration and different ethnic backgrounds on cervical, colon and oesophageal cancer risk and survival. Methods: Cancers diagnosed in 1996–2009 were selected from The Netherlands Cancer Registry. Besides standardized incidence ratios, differences in survival were explored using Cox [...]

Menée en population belge à partir d'échantillons cytologiques recueillis lors d'examens gynécologiques de routine, cette étude analyse la prévalence, ainsi que la charge virale, d'une infection par 51 types et 3 sous-types de papillomavirus humain

Prevalence and viral load of 51 genital human papillomavirus types and three subtypes

Schmitt, Markus ; Depuydt, Christophe ; Benoy, Ina ; Bogers, Johannes ; Antoine, Jerome ; Arbyn, Marc ; Pawlita, Michael ; on behalf of the, Valgent Study Group

Of the 120 known human papillomaviruses (HPV), 51 HPV types infect the genital mucosa. Very little is known about the prevalence and viral load of the majority of these low-risk (Lr-) HPV types in screening populations. We determined the prevalence of 51 HPV types and three subtypes in 999 consecutive BD-SurePath™ liquid-based cervical cytology samples collected during routine gynecological health checks from Belgian women. This series of screening samples was enriched with ASC-US (n = 100), [...]

Menée auprès de parents de 44 enfants survivants d'un cancer, cette étude analyse leur stress associé à la surveillance d'effets neurocognitifs indésirables causés par les traitements sur leurs enfants

Parenting stress and neurocognitive late effects in childhood cancer survivors

Patel, Sunita K. ; Wong, Andrew L. ; Cuevas, Michelle ; Horn, Hillary Van

Background Surveillance of neurocognitive late effects has typically focused on the pediatric survivor alone and rarely has focused on the potential family burden. We investigated the impact of child neurocognitive effects on parenting stress and hypothesized that parents of childhood cancer survivors with greater executive difficulties experience higher stress relative to parents of children with less adverse impact. Methods Parents of 44 children who survived cancer involving central nervous [...]

Menée auprès de 11 groupes de participants âgés de 30 à 49 ans, cette étude américaine analyse les perceptions des Amérindiens vis-à-vis du dépistage du cancer colorectal

American Indian Perceptions of Colorectal Cancer Screening: Viewpoints from Adults Under Age 50

Filippi, Melissa ; Braiuca, Stacy ; Cully, Lance ; James, Aimee ; Choi, Won ; Greiner, K. ; Daley, Christine

Colorectal cancer (CRC) mortality rates have decreased in the general US population; however, CRC mortality rates are increasing among American Indians (AI). AI CRC screening rates remain low when compared to other ethnic groups. Our team investigated CRC screening education prior to recommended age for screening to better understand screening perceptions among AI community members. Our research team conducted 11 focus groups with AI men and women aged 30–49 ( N = 39 men and N = 31 women) in [...]

Mené au Royaume-Uni auprès de 145 patients atteints d'un cancer de la tête et du cou, cet essai randomisé analyse et compare l'efficacité de sessions d'acupuncture et de sessions de formation à des soins oraux pour traiter une xérostomie chronique liée à la radiothérapie

ARIX: A randomised trial of acupuncture v oral care sessions in patients with chronic xerostomia following treatment of head and neck cancer

Simcock, R. ; Fallowfield, L. ; Monson, K. ; Solis-Trapala, I. ; Parlour, L. ; Langridge, C. ; Jenkins, V. ; on behalf of the ARIX Steering Committee

Background Radiation treatment of head and neck cancer can cause chronic xerostomia which impairs patients' quality of life. The study reported here examined the efficacy of acupuncture in alleviating xerostomia symptoms especially dry mouth.Patients and methods A total of 145 patients with chronic radiation-induced xerostomia >18 months after treatments were recruited from seven UK cancer centres. The study employed a randomised crossover design with participants receiving two group sessions [...]