Menée au Royaume-Uni à l'aide de données d'une enquête réalisée sur la période 2015-2021 auprès de 10 229 participants (âge : 10-25 ans), cette étude analyse la transition entre une utilisation de produits à base de nicotine (notamment la cigarette électronique) et une pratique tabagique ou son arrêt

Multistate transition modelling of e-cigarette use and cigarette smoking among youth in the UK

Parnham, Jennie C ; Vrinten, Charlotte ; Radó, Márta K ; Bottle, Alex ; Filippidis, Filippos T ; Laverty, Anthony A

Introduction: E-cigarette use remains a controversial topic, with questions over how people transition between e-cigarette use and cigarette smoking. This paper examined transitions into and out of nicotine product use in a representative sample of UK youth. Methods: We used Markov multistate transition probability models on data from 10 229 participants (10–25 years old) in the UK Household Longitudinal Study (2015–2021). We used four product use states (‘never’, ‘non-current use’, [...]

Menée aux Etats-Unis à partir de données d'enquêtes réalisées sur la période 2016-2019 auprès de 5 186 anciens fumeurs, cette étude analyse, en fonction de la durée de l'abstinence tabagique, l'effet de bons de réduction pour l'achat de cigarettes sur la récidive du tabagisme

Cigarette Coupon Receipt and Smoking Relapse by Duration of Smoking Abstinence

Wang, Yu ; Duan, Zongshuan ; Weaver, Scott R. ; Self-Brown, Shannon R. ; Ashley, David L. ; Emery, Sherry L. ; Pechacek, Terry F. ; Huang, Jidong

Introduction: It is unknown whether and to what extent the duration of smoking abstinence may modify the association between receiving cigarette coupons and smoking relapse in the U.S. This study aims to fill this gap. Methods: Data were from the Population Assessment of Tobacco and Health study Wave 4 (December 2016–January 2018, baseline) and Wave 5 (December 2018–November 2019, follow-up) surveys. Analysis was conducted in May 2022. The study sample was participants who formerly smoked [...]

Menée à partir de données de 11 études portant au total sur 7 792 témoins et 3 900 patients atteints d'un cancer de l'estomac, cette étude analyse l'association entre la quantité de champignons consommée et le risque de développer la maladie

Mushroom consumption and risk of gastric cancer: a pooled analysis within the stomach cancer pooling project and a combined meta-analysis with other observational studies

Ba, Djibril M. ; Ssentongo, Paddy ; Pelucchi, Claudio ; Negri, Eva ; Palli, Domenico ; Ferraroni, Monica ; Zhang, Zuo-Feng ; Yu, Guo-Pei ; Tsugane, Shoichiro ; Hidaka, Akihisa ; Hamada, Gerson Shigueaki ; Zaridze, David ; Maximovich, Dmitry ; Obón-Santacana, Mireia ; Álvarez-Álvarez, Laura ; Vioque, Jesús ; Garcia de la Hera, Manoli ; López-Carrillo, Lizbeth ; López-Cervantes, Malaquias ; Mu, Lina ; Lagiou, Areti ; Lagiou, Pagona ; Boffetta, Paolo ; Camargo, Maria Constanza ; Curado, Maria Paula ; Lunet, Nuno ; La Vecchia, Carlo ; Muscat, Joshua

Edible mushrooms have high concentrations of vitamins and minerals. They are considered ‘functional foods’ for their disease-prevention properties. Mushroom consumption may reduce the risk of gastric cancer, the fifth most common cancer worldwide. We investigated the association between mushroom consumption and gastric cancer risk in a pooled analysis within the Stomach Cancer Pooling (StoP) Project and in a meta-analysis that also included previously published studies. A total of 3900 gastric [...]

Menée ex vivo à l'aide d'une technique de coupe de précision de tissus pulmonaires, cette étude analyse l'effet de l'iloprost sur le risque de cancer du poumon non à petites cellules

Precision cut lung slices as a preclinical model for non-small cell lung cancer chemoprevention

Sompel, Kayla ; Smith, Alex J. ; Hauer, Caroline ; Elango, Alamelu P. ; Clambey, Eric T. ; Keith, Robert L. ; Tennis, Meredith A.

Lung cancer chemoprevention is critical to addressing cancer burden in high-risk populations. Chemoprevention clinical trials rely on data from pre-clinical models however, in vivo studies have high financial, technical, and staffing requirements. Precision cut lung slices (PCLS) provide an ex vivo model that maintains the structure and function of native tissues. This model can be used for mechanistic investigations and drug screenings and reduces the number of animals and time required to [...]

Menée à partir de données 2004-2018 de registres norvégiens portant sur 1 083 629 femmes âgées d'au moins 50 ans (durée médiane de suivi : 11,6 ans), cette étude analyse l'association entre l'utilisation de faibles doses d'aspirine et le risque de cancer du sein

Low-dose aspirin and risk of breast cancer: a Norwegian population-based cohort study of one million women

Løfling, Lukas ; Støer, Nathalie C. ; Nafisi, Sara ; Ursin, Giske ; Hofvind, Solveig ; Botteri, Edoardo

Several studies evaluated the association between aspirin use and risk of breast cancer (BC), with inconsistent results. We identified women aged ≥ 50 years residing in Norway between 2004 and 2018, and linked data from nationwide registries; including the Cancer Registry of Norway, the Norwegian Prescription Database, and national health surveys. We used Cox regression models to estimate the association between low-dose aspirin use and BC risk, overall and by BC characteristics, women’s age [...]

Menée à partir des données d'une enquête réalisée aux Etats-Unis sur la période 2011-2020, cette étude analyse l'évolution du taux de vaccination contre le papillomavirus humain (HPV) chez les adolescents âgés de 13 à 17 ans et identifie les facteurs de défiance des parents vis-à-vis du vaccin anti-HPV

Trends in adolescent human papillomavirus vaccination and parental hesitancy in the United States

White, Jodie L ; Grabowski, M Kate ; Rositch, Anne F ; Gravitt, Patti E ; Quinn, Thomas C ; Tobian, Aaron A R ; Patel, Eshan U

Human papillomavirus (HPV) vaccination coverage remains suboptimal in the U.S., underscoring the importance of monitoring trends in vaccine hesitancy.Cross-sectional data from the 2011-2020 National Immunization Survey-Teen were used to assess trends in provider-verified HPV vaccination initiation (≥1 dose) among 13-17-year-olds, parental intent to initiate vaccination, and primary reasons for parental hesitancy.Among all sex and race and ethnicity groups, prevalence of HPV vaccination [...]

Menée en Norvège à l'aide de données 2006-2016 de registres nationaux des vaccinations et des cancers et menée auprès de 832 732 femmes nées entre 1975 et 1996, cette étude analyse l'effet du vaccin contre le papillomavirus humain sur l'incidence des néoplasies cervicales intraépithéliales de haut grade (CIN2+) en fonction de l'âge à la vaccination

Real-World Effectiveness of Hpv Vaccination Against Cervical Neoplasia Among Birth Cohorts Ineligible for Routine Vaccination

Dong, Li ; Nygård, Mari ; Støer, Nathalie C ; Klungsøyr, Ole ; Hansen, Bo T

Human papillomavirus (HPV) vaccine effectiveness may differ between settings. Here we present the first real-world effectiveness study of HPV vaccination on high-grade cervical lesions from Norway, among women who received HPV vaccine outside the routine program. We performed an observational study of all Norwegian women born 1975-1996 and retrieved individual data from nationwide registries on HPV vaccination status and incidence of histologically verified high-grade cervical neoplasia during [...]