Microbiota regulates intratumoral monocytes to promote anti-tumor immune responses

Menée in vitro et à l'aide de modèles murins, cette étude met en évidence un mécanisme par lequel les signaux du microbiote régulent les monocytes intratumoraux

Résumé en anglais

The gut microbiota has been shown to promote the efficacy of cancer therapy through regulating adaptive immune responses. In this issue of Cell, Lam et al. provide new evidence demonstrating that specific gut bacteria also reprogram the innate immune tumor microenvironment to enhance the efficacy of cancer therapies.