Cette étude analyse les recommandations internationales concernant la prévention et le traitement d'une maladie thromboembolique veineuse chez des patients atteints d'un cancer

2019 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer

Farge, Dominique ; Frere, Corinne ; Connors, Jean M. ; Ay, Cihan ; Khorana, Alok A. ; Muñoz, Andrés ; Brenner, Benjamin ; Kakkar, Ajay ; Rafii, Hanadi ; Solymoss, Susan ; Brilhante, Dialina ; Monreal, Manuel ; Bounameaux, Henri ; Pabinger, Ingrid ; Douketis, James ; Ageno, Walter ; Ajauro, Fernando ; Al-Aboudi, Kamal R. ; Alcindor, Thierry ; André, Thierry ; Angchaisuksiri, Pantep ; Antic, Darko ; Arcelus, Juan I. ; Assenat, Eric ; Bauer, Kenneth A. ; Bazarbachii, Ali ; Benzidia, Ilham ; Beyer-Westendorf, Jan ; Bitsadze, Viktoria ; Blickstein, Dorit ; Blostein, Marc ; Bogalho, Isabel ; Bournet, Barbara ; Casais, Patricia ; Carpentier, Antoine ; Cesaraman, Gabriela ; Chakbrabartty, Joydeep ; Clemente, Hugo A. ; Connault, Jérôme ; Doucet, Ludovic ; Durant, Cécile ; Emmerich, Joseph ; Falanga, Anna ; Feistritzer, Clemens ; Font, Carme ; Francis, Charles ; Gallardo, Enrique ; Gary, Thomas ; Gris, Jean-Christophe ; Guillermo, Cecilia ; Hij, Adrian ; Hull, Russel D. ; Ikezoe, Takayuki ; Juan-Palomares, Luis ; Key, Nigel S. ; Khrizroeva, Jamilya ; Koolian, Maral ; Länger, Florian ; Hello, Claire ; Lecumberri, Ramos ; Lee, Lai Heng ; Liebman, Howard ; Dos Santos, Luisa Lopes ; Machado, Durate Henrique ; Madelaine, Isabelle ; Makatsariya, Alexander ; Mandalà, Mario ; Marayevas, Anthony ; Marjanovic, Zora ; Marosi, Christine ; Martin, Ellis ; Meillon, Luis ; Messas, Emmanuel ; Moreira, Antonio ; Demir, Ahmet M. ; Ndour, Arlette ; Nguessan, Michel ; Otero-Candelera, Remedios ; Olmos, Vanessa Pachon ; Pais, Ana ; Posch, Florian ; Preusser, Matthias ; Riess, Hanno ; Righini, Marc ; Rothschild, Cynthia ; Roussin, Andre ; Rueda-Camino, José Antonio ; Ruiz-Artacho, Pedro ; Saseedharan, Sanjith ; Shamseddine, Ali ; Soff, Gerald ; Stricker, Hans ; Tagalakis, Vicky ; Taher, Ali ; Toussaint, Toutou ; Trujillo-Santos, Javier ; Villiers, Stéphane ; Wong, Raymond ; Yamada, Norizaku

Venous thromboembolism (VTE) is the second leading cause of death in patients with cancer. These patients are at a high risk of VTE recurrence and bleeding during anticoagulant therapy. The International Initiative on Thrombosis and Cancer is an independent academic working group aimed at establishing a global consensus for the treatment and prophylaxis of VTE in patients with cancer. The International Initiative on Thrombosis and Cancer last updated its evidence-based clinical practice [...]

Menée en Allemagne par questionnaire auprès de 1 577 patients atteints d'un cancer de la prostate, cette étude transversale analyse l'association entre leur capacité à trouver et à comprendre l'information médicale, la peur de la progression de la maladie et la qualité de vie

Quality of life and fear of disease progression are associated with aspects of health literacy in men with prostate cancer from Germany

Haack, Marius ; Kramer, Silke ; Seidel, Gabriele ; Dierks, Marie-Luise

Purpose : Our research aimed to identify whether specific aspects of health literacy (HL) are associated with quality of life (QOL) and fear of progression (FOP) in men with prostate cancer (PC). Methods : We conducted a cross-sectional study. Regarding HL, we surveyed communication skills, guideline awareness, and knowledge in several domains: PC, health care system, own physical condition, dealing with health problems. Research questions were addressed using regression models for QOL and FOP [...]

Menée aux Etats-Unis auprès de 100 patientes ayant survécu à un cancer de l'endomètre de stade I, souffrant d'obésité et incluses dans une intervention pour perdre du poids (âge moyen : 60 ans), cette étude analyse l'association entre la qualité du sommeil, des symptômes de dépression et la qualité de vie

Sleep, quality of life, and depression in endometrial cancer survivors with obesity seeking weight loss

Nock, Nora L. ; Dimitropoulos, Anastasia ; Zanotti, Kristine M. ; Waggoner, Steven ; Nagel, Christa ; Golubic, Mladen ; Michener, Chad M. ; Kirwan, John P. ; Alberts, Jay

Purpose : Incidence and mortality rates of uterine cancer are increasing and, obesity, which is also rising, has been associated with uterine cancer development and mortality. A recent study found that poor sleep quality is common among endometrial cancer survivors and those with obesity had more sleep disturbances than those having normal weight. However, it is unclear if higher levels of obesity (Class III, BMI ≥ 40 kg/m2), which are rising rapidly, are differentially associated with sleep as [...]

Menée au Canada à partir de données portant sur 26 463 patients atteints d'un cancer, cette étude analyse l'efficacité du vaccin contre la grippe saisonnière

Influenza Vaccine Effectiveness Among Patients With Cancer: A Population-Based Study Using Health Administrative and Laboratory Testing Data From Ontario, Canada

Phillip S. Blanchette ; Hannah Chung ; Kathleen I. Pritchard ; Craig C. Earle ; Michael A. Campitelli ; Sarah A. Buchan ; Kevin L. Schwartz ; Natasha S. Crowcroft ; Jonathan B. Gubbay ; Timothy Karnauchow ; Kevin Katz ; Allison J. McGeer ; James D. McNally ; David C. Richardson ; Susan E. Richardson ; Laura C. Rosella ; Andrew Simor ; Marek Smieja ; George Zahariadis ; Aaron Campigotto ; Jeffrey C. Kwong

PURPOSE : Seasonal influenza vaccination is recommended for patients with cancer despite concerns of disease or treatment-associated immunosuppression. The objective of this study was to evaluate vaccine effectiveness (VE) against laboratory-confirmed influenza for patients with cancer. PATIENTS AND METHODS : We conducted an observational test-negative design study of previously diagnosed patients with cancer 18 years of age and older who underwent influenza testing during the 2010-2011 to [...]

Menée dans 21 pays des 5 continents à partir de données portant sur 162 534 participants entre 2005 et 2016, cette étude de cohorte prospective analyse les disparités géographiques dans l'incidence de maladies communes (dont le cancer), les hospitalisations et la mortalité associées

Variations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): a prospective cohort study

Dagenais, Gilles R. ; Leong, Darryl P. ; Rangarajan, Sumathy ; Lanas, Fernando ; Lopez-Jaramillo, Patricio ; Gupta, Rajeev ; Diaz, Rafael ; Avezum, Alvaro ; Oliveira, Gustavo B. F. ; Wielgosz, Andreas ; Parambath, Shameena R. ; Mony, Prem ; Alhabib, Khalid F. ; Temizhan, Ahmet ; Ismail, Noorhassim ; Chifamba, Jephat ; Yeates, Karen ; Khatib, Rasha ; Rahman, Omar ; Zatonska, Katarzyna ; Kazmi, Khawar ; Wei, Li ; Zhu, Jun ; Rosengren, Annika ; Vijayakumar, K. ; Kaur, Manmeet ; Mohan, Viswanathan ; Yusufali, AfzalHussein ; Kelishadi, Roya ; Teo, Koon K. ; Joseph, Philip ; Yusuf, Salim

Background : To our knowledge, no previous study has prospectively documented the incidence of common diseases and related mortality in high-income countries (HICs), middle-income countries (MICs), and low-income countries (LICs) with standardised approaches. Such information is key to developing global and context-specific health strategies. In our analysis of the Prospective Urban Rural Epidemiology (PURE) study, we aimed to evaluate differences in the incidence of common diseases, related [...]

Menée à partir des données des registres américains des cancers portant sur 9 042 patients atteints d'un lymphome hodgkinien classique de stade avancé, diagnostiqué entre 2000 et 2014 et traité par chimiothérapie (âge médian : 41 ans), cette étude analyse l'évolution de la survie globale sur les sous-périodes 2000–2004, 2005–2009 et 2010–2014

Contemporary Outcomes for Advanced-Stage Classical Hodgkin Lymphoma in the U.S.: Analysis of Surveillance, Epidemiology, and End Results Database

Guru Murthy, Guru Subramanian ; Szabo, Aniko ; Hamadani, Mehdi ; Fenske, Timothy S. ; Shah, Nirav N.

Background : Advanced‐stage Hodgkin lymphoma (HL) is a curable malignancy, although outcomes remain poor in certain patients. It remains unclear if recent advances have improved their population‐level survival over time. Materials and Methods : Using the Surveillance, Epidemiology, and End Results database, we identified patients aged ≥18 years with stage III or IV classical HL as the first primary malignancy, diagnosed between 2000 and 2014 and treated with chemotherapy. Patients were [...]

A partir d'une revue systématique de la littérature publiée jusqu'en octobre 2018 (38 articles, 3 274 patients), cette méta-analyse d'essais randomisés évalue l'efficacité d'interventions de nature psychosociale basées sur le concept de la pleine conscience pour améliorer la santé psychique et physique des patients atteints d'un cancer ou ayant survécu à un cancer

Mindfulness-based interventions for psychological and physical health outcomes in cancer patients and -survivors: a systematic review and meta-analysis of randomized controlled trials

Cillessen, L. ; Johannsen, M. ; Speckens, A.E.M. ; Zachariae, R.

Objective : Mindfulness‐based interventions (MBIs) are increasingly used within psycho‐oncology. Since the publication of the most recent comprehensive meta‐analysis on MBIs in cancer in 2012, the number of published trials has more than doubled. We therefore conducted a systematic review and meta‐analysis of randomized controlled trials (RCTs), testing the efficacy of MBIs on measures of psychological distress (primary outcome) and other health outcomes in cancer patients and ‐survivors. [...]

Menée au Canada auprès de 461 jeunes adultes atteints d'un cancer diagnostiqué entre 15 et 39 ans (âge moyen lors de l'étude : 32 ans), cette étude identifie les facteurs associés à leur peur de la récidive

Prevalence and factors associated with fear of recurrence in a mixed sample of young adults with cancer

Lane, Breanna E. ; Garland, Sheila N. ; Chalifour, Karine ; Eaton, Geoff ; Lebel, Sophie ; Galica, Jacqueline ; Maheu, Christine ; Simard, Sébastien

Purpose : This study examined the prevalence and factors associated with fear of cancer recurrence (FCR) in young adults (YAs). Methods : YAs diagnosed with cancer between the ages of 15 and 39 in Canada (n = 461), who were currently 19 years or older, completed the Young Adults with Cancer in their Prime (YACPRIME) Study. The Fear of Cancer Recurrence Inventory Short Form (FCRI-SF) was the primary outcome. Scores ≥ 16 on the FCRI-SF indicate problematic levels and scores ≥ 22 represent [...]

A partir d'une revue de la littérature, cette étude analyse, dans différents pays, l'utilisation des soins palliatifs chez les patients atteints d'un gliome

Palliative care in glioma management

Oberndorfer, Stefan ; Hutterer, Markus

Purpose of review :The concept of palliative care is becoming increasingly important in the management of glioma patients. However, the right time for implementation, as well as the individual degree of integration of palliative care aspects, are still a matter of debate. This review updates recent evidence of palliative care in glioma and raises questions for future developments. Recent findings: According to the disease-specific aspects of palliative care in glioma management, there is an [...]