Annual Report to the Nation on the Status of Cancer, 1999–2015, Featuring Cancer in Men and Women ages 20–49

Mené aux Etats-Unis, ce rapport présente les données d'incidence et de mortalité liées au cancer sur la période 1999-2015, en mettant l'accent sur les jeunes adultes âgés de 20 à 49 ans

Journal of the National Cancer Institute, sous presse, 2019, résumé

Résumé en anglais

Background : The American Cancer Society, Centers for Disease Control and Prevention, National Cancer Institute, and North American Association of Central Cancer Registries (NAACCR) provide annual updates on cancer occurrence and trends by cancer type, sex, race, ethnicity, and age in the US. This year’s report highlights the cancer burden among men and women ages 20–49 years.

Methods : Incidence data from the Centers for Disease Control and Prevention- and National Cancer Institute- funded population-based cancer registry programs compiled by NAACCR and death data from the National Vital Statistics System were used. Trends in age-standardized incidence and death rates, estimated by joinpoint, were expressed as average annual percent change.

Results : Overall cancer incidence rates (per 100,000) for all ages during 2011–2015 were 494.3 among men and 420.5 among women; during the same time period, incidence rates decreased 2.1% (95% confidence interval [CI] = –2.6% to –1.6%) per year in males and were stable in females. During 2012–2016, overall cancer death rates for all ages decreased 1.8% (95% CI = –1.8% to –1.8%) per year in males and 1.4% (95% CI =–1.4% to –1.4%) per year in females. Important changes in trends were stabilization of thyroid cancer incidence rates in women and rapid declines in death rates for melanoma of the skin (both sexes). Among adults ages 20–49, overall cancer incidence rates were substantially lower among males (115.3 per 100,000) than among females (203.3 per 100,000); cancers with the highest incidence rates (per 100,000) among males were colon and rectum (13.1), testis (10.7) and melanoma of the skin (9.8) and among females were breast (73.2), thyroid (28.4) and melanoma of the skin (14.1). During 2011 to 2015, the incidence of all invasive cancers combined among adults ages 20–49 decreased among males (five-year AAPC = –0.7%; 95% CI = –1.0% to –0.4%) and increased among females (1.3%; 95% CI = 0.7% to 1.9%). The death rate (per 100,000) adults ages 20–49 for all cancer sites combined during 2012 to 2016 was 22.8 among males and 27.1 among females; during the same time period, death rates decreased 2.3% (95% CI = –2.4% to –2.2%) per year among males and 1.7% (95% CI = –1.8% to –1.6%) per year among females..

Conclusions : Among people of all ages and ages 20–49, both favorable and unfavorable trends in site-specific cancer incidence were observed, while trends in death rates were generally favorable. Characterizing the cancer burden may inform research and cancer control efforts.