Menée aux Etats-Unis auprès de 256 patients atteints d'un cancer de stade avancé (âge moyen : 58 ans) et participant à un essai clinique de phase précoce pour des thérapies ciblées, cette étude évalue l'association entre la qualité du sommeil, la fatigue, divers symptômes et les troubles de l'humeur

Sleep quality and its association with fatigue, symptom burden, and mood in patients with advanced cancer in a clinic for early-phase oncology clinical trials

George, Goldy C. ; Iwuanyanwu, Eucharia C. ; Anderson, Karen O. ; Yusuf, Alizeh ; Zinner, Ralph G. ; Piha-Paul, Sarina A. ; Tsimberidou, Apostolia M. ; Naing, Aung ; Fu, Siqing ; Janku, Filip ; Subbiah, Vivek ; Cleeland, Charles S. ; Mendoza, Tito R. ; Hong, David S.

BACKGROUND Limited data exist about sleep quality for patients with advanced cancer in phase 1 clinical trials. Poor sleep quality is often not captured as an adverse event, and its association with fatigue, one of the most frequently reported adverse events, is not documented routinely. This article describes sleep quality and its relation with fatigue, symptom burden, and mood in patients recruited from an early-phase clinic for targeted therapy. METHODS Sleep, fatigue, symptom burden, and [...]

Cette étude présente des recommandations pour la prévention des réactions cutanées indésirables induites par les inhibiteurs d'EGFR chez les patients atteints de tumeurs solides

Recommendations for the Prophylactic Management of Skin Reactions Induced by Epidermal Growth Factor Receptor Inhibitors in Patients With Solid Tumors

Hofheinz, Ralf-Dieter ; Deplanque, Gael ; Komatsu, Yoshito ; Kobayashi, Yoshimitsu ; Ocvirk, Janja ; Racca, Patrizia ; Guenther, Silke ; Zhang, Jun ; Lacouture, Mario E. ; Jatoi, Aminah

Inhibition of the epidermal growth factor receptor (EGFR) is an established treatment that extends patient survival across a variety of tumor types. EGFR inhibitors fall into two main categories: anti-EGFR monoclonal antibodies, such as cetuximab and panitumumab, and first-generation tyrosine kinase inhibitors, such as afatinib, gefitinib, and erlotinib. Skin reactions are the most common EGFR inhibitor-attributable adverse event, resulting in papulopustular (acneiform) eruptions that can be [...]

Menée aux Pays-Bas auprès de 3 407 patients atteints de cancer et soignés en ambulatoire, cette étude évalue l'efficacité d'un programme informatique sur écran tactile permettant aux patients de déclarer l'intensité de leurs douleurs

To be in pain (or not): a computer enables outpatients to inform their physician

Oldenmenger, W. H. ; Witkamp, F. E. ; Bromberg, J. E. C. ; Jongen, J. L. M. ; Lieverse, P. J. ; Huygen, F. J. P. M. ; Baan, M. A. G. ; van Zuylen, L. ; van der Rijt, C. C. D.

Background : In the outpatient oncology clinic, pain management is often inadequate. Incorporating a systematic pain management program into visits is likely to improve this. We implemented an integrated program, including a structured pain assessment, pain treatment protocol and patient education module. In the present study, we investigated whether this intervention improved pain control. Patients and methods : At seven oncology outpatient clinics, patients were asked to register their pain [...]

Cette étude analyse les recommandations de l'"American Society of Clinical Oncology" pour la prise en charge des douleurs chroniques chez les patients adultes ayant survécu à un cancer

Management of Chronic Pain in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline

Paice, Judith A. ; Portenoy, Russell ; Lacchetti, Christina ; Campbell, Toby ; Cheville, Andrea ; Citron, Marc ; Constine, Louis S. ; Cooper, Andrea ; Glare, Paul ; Keefe, Frank ; Koyyalagunta, Lakshmi ; Levy, Michael ; Miaskowski, Christine ; Otis-Green, Shirley ; Sloan, Paul ; Bruera, Eduardo

Purpose : To provide evidence-based guidance on the optimum management of chronic pain in adult cancer survivors. Methods : An ASCO-convened expert panel conducted a systematic literature search of studies investigating chronic pain management in cancer survivors. Outcomes of interest included symptom relief, pain intensity, quality of life, functional outcomes, adverse events, misuse or diversion, and risk assessment or mitigation.Results A total of 63 studies met eligibility criteria and [...]

Menée au Japon auprès de 28 patients atteints de cancer, cette étude rétrospective évalue l'efficacité de la méthadone en remplacement d'autres opioïdes forts tels que l'oxycodone et le fentanyl pour traiter les douleurs neuropathiques sévères liées à la maladie, sans utiliser d'analgésiques adjuvants

A Retrospective Study on the Effectiveness of Switching to Oral Methadone for Relieving Severe Cancer-Related Neuropathic Pain and Limiting Adjuvant Analgesic Use in Japan

Sugiyama, Yosuke ; Sakamoto, Nobuhiro ; Ohsawa, Masahiro ; Onizuka, Mami ; Ishida, Kyoko ; Murata, Yuki ; Iio, Ayaka ; Sugano, Koji ; Maeno, Ken ; Takeyama, Hiromitsu ; Akechi, Tatsuo ; Kimura, Kazunori

Background: Cancer-related neuropathic pain is resistant to treatment with multiple medications and results in reduced patient quality of life. Objective: The aim was to find a new curative to treat neuropathic pain without using adjuvant analgesics. Design: This was a retrospective study that used the FACES Pain Scale (FPS) to measure pain intensity and pain relief. Setting/Subjects: Twenty-eight inpatients who were treated with other strong opioids and who consulted the palliative care team [...]

Cette étude présente des recommandations pour améliorer la prise en charge de patientes ayant survécu à un cancer diagnostiqué avant l'âge de 25 ans et présentant un risque d'insuffisance ovarienne prématurée liée aux traitements par agents alkylants et/ou radiothérapie

Recommendations for Premature Ovarian Insufficiency Surveillance for Female Survivors of Childhood, Adolescent, and Young Adult Cancer: A Report From the International Late Effects of Childhood Cancer Guideline Harmonization Group in Collaboration With the PanCareSurFup Consortium

van Dorp, Wendy ; Mulder, Renée L. ; Kremer, Leontien C.M. ; Hudson, Melissa M. ; van den Heuvel-Eibrink, Marry M. ; van den Berg, Marleen H. ; Levine, Jennifer M. ; van Dulmen-den Broeder, Eline ; di Iorgi, Natascia ; Albanese, Assunta ; Armenian, Saro H. ; Bhatia, Smita ; Constine, Louis S. ; Corrias, Andreas ; Deans, Rebecca ; Dirksen, Uta ; Gracia, Clarisa R. ; Hjorth, Lars ; Kroon, Leah ; Lambalk, Cornelis B. ; Landier, Wendy ; Levitt, Gill ; Leiper, Alison ; Meacham, Lillian ; Mussa, Alesandro ; Neggers, Sebastian J. ; Oeffinger, Kevin C. ; Revelli, Alberto ; van Santen, Hanneke M. ; Skinner, Roderick ; Toogood, Andrew ; Wallace, William H. ; Haupt, Riccardo

Purpose : Female survivors of childhood, adolescent, and young adult (CAYA) cancer who were treated with alkylating agents and/or radiation, with potential exposure of the ovaries, have an increased risk of premature ovarian insufficiency (POI). Clinical practice guidelines can facilitate these survivors’ access to optimal treatment of late effects that may improve health and quality of survival; however, surveillance recommendations vary among the existing long-term follow-up guidelines, which [...]

Menée sur un modèle murin, cette étude analyse l'efficacité d'une thérapie génique augmentant l'expression du gène Smad7 pour prévenir une atrophie musculaire associée à une cachexie chez les patients atteints d'un cancer de stade avancé

Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice

Winbanks, Catherine E. ; Murphy, Kate T. ; Bernardo, Bianca C. ; Qian, Hongwei ; Liu, Yingying ; Sepulveda, Patricio V. ; Beyer, Claudia ; Hagg, Adam ; Thomson, Rachel E. ; Chen, Justin L. ; Walton, Kelly L. ; Loveland, Kate L. ; McMullen, Julie R. ; Rodgers, Buel D. ; Harrison, Craig A. ; Lynch, Gordon S. ; Gregorevic, Paul

An unfortunate morbidity associated with cancer is muscle wasting, known as cachexia, where healthy cells erode in the face of malignancy. Cachexia has been difficult to treat, and the most promising new therapies inhibiting ActRIIB ligands, such as myostatin, a protein that promotes muscle breakdown, have been pulled after clinical trials indicated safety issues. Targeting ActRIIB ligands may still be possible—just in a different way, to avoid toxicity. Winbanks et al. demonstrated that gene [...]

Menée à partir de données du registre australien des cancers incluant 539 patients atteint d'un cancer colorectal, cette étude analyse l'évolution de leur état de santé au cours des deux premières années suivant le diagnostic (difficultés dans les tâches quotidiennes et dans leur mobilité, douleur, gêne, anxiété, dépression)

Experiences of colorectal cancer patients in the 2-years post-diagnosis and patient factors predicting poor outcome

Paul, Christine L. ; Cameron, Emilie ; Doran, Christopher ; Hill, David ; Macrae, Finlay ; Carey, Mariko L. ; Sanson-Fisher, Rob W.

Purpose : There are few recent longitudinal studies investigating the quality of life of colorectal cancer patients in the early years following diagnosis. This study aimed to (i) compare the health status of people with colorectal cancer less than 1 year from diagnosis with health status 1 year later and (ii) determine the characteristics associated with a change in overall health status. Methods : The study was conducted as part of a larger trial. Participants (n = 539) were identified via [...]

A partir d'une revue systématique de la littérature (13 études), cette étude évalue l'efficacité d'une structuration du parcours de soins pour améliorer la prise en charge thérapeutique des patientes atteintes d'un cancer du sein et leur qualité de vie dans l'après-cancer

Patient Navigation in Breast Cancer Treatment and Survivorship: A Systematic Review

Baik, Sharon H. ; Gallo, Linda C. ; Wells, Kristen J.

Purpose : Patient navigation is an intervention approach that improves cancer outcomes by reducing barriers and facilitating timely access to cancer care. Little is known about the benefits of patient navigation during breast cancer treatment and survivorship. This systematic review evaluates the efficacy of patient navigation in improving treatment and survivorship outcomes in women with breast cancer. Methods : The review included experimental and quasi-experimental studies of patient [...]

Menée en Italie auprès de 30 patients atteints d'un cancer de la tête et du cou (âge moyen : 64,9 ans), cette étude de cohorte évalue l'efficacité de tapentadol à libération prolongée pour prendre en charge les douleurs associées à une mucite buccale pendant une radiothérapie avec modulation d'intensité avec ou sans cisplatine

Effectiveness of tapentadol prolonged release for the management of painful mucositis in head and neck cancers during intensity modulated radiation therapy

Rosario, Mazzola ; Francesco, Ricchetti ; Sergio, Fersino ; Niccolò, Giaj Levra ; Alba, Fiorentino ; Maurizio, Nicodemo ; Sergio, Albanese ; Stefania, Gori ; Filippo, Alongi

Purpose : To evaluate the effectiveness and tolerability profile of tapentadol prolonged release (PR) in a cohort of head and neck cancer (HNC) patients affected by background pain due to painful mucositis during intensity modulated radiation therapy with or without cisplatin with definitive and adjuvant intent. Materials and methods : Tapentadol PR was administered at the moment of pain onset in opioid-naive patients at the dosage of 50 mg BID. The dosage was increased 50 mg twice a day until [...]

Menée aux Etats-Unis auprès de parents de patients adolescents (âges de 12 à 17 ans) ayant survécu à un cancer pédiatrique entre 1970 et 1999, cette étude analyse l'association entre les traitements reçus (radiothérapie crânienne ou non), les comorbidités et les divers types de symptômes (comportementaux, émotionnels, sociaux)

Behavioral, Social, and Emotional Symptom Comorbidities and Profiles in Adolescent Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study

Brinkman, Tara M. ; Li, Chenghong ; Vannatta, Kathryn ; Marchak, Jordan G. ; Lai, Jin-Shei ; Prasad, Pinki K. ; Kimberg, Cara ; Vuotto, Stefanie ; Di, Chongzhi ; Srivastava, Deokumar ; Robison, Leslie L. ; Armstrong, Gregory T. ; Krull, Kevin R.

Purpose : In the general population, psychological symptoms frequently co-occur; however, profiles of symptom comorbidities have not been examined among adolescent survivors of childhood cancer. Patients and Methods : Parents of 3,893 5-year survivors of childhood cancer who were treated between 1970 and 1999 and who were assessed in adolescence (age 12 to 17 years) completed the Behavior Problems Index. Age- and sex-standardized z scores were calculated for symptom domains by using the [...]

Menée en Australie auprès de pompiers masculins professionnels, cette étude de cohorte évalue l'incidence de cancer et la mortalité spécifique, en fonction de la durée de leur activité professionnelle et du type d'incidents rencontrés

Mortality and cancer incidence in a cohort of male paid Australian firefighters

Glass, D C ; Pircher, S ; Del Monaco, A ; Hoorn, S Vander ; Sim, M R

Objectives : To investigate mortality and cancer incidence of paid male Australian firefighters and of subgroups of firefighters by era of first employment, duration of employment and number and type of incidents attended. Methods : Participating fire agencies supplied records of individual firefighters including their job histories and incidents attended. The cohort was linked to the Australian National Death Index and Australian Cancer Database. SMRs and SIRs were calculated. Firefighters [...]

Menée aux Etats-Unis à partir de données d'enquêtes auprès de 538 969 participants âgés de 18 à 85 ans, cette étude évalue l'évolution de la prévalence de l'obésité chez les patients ayant survécu à un cancer (32 447 cas) sur la période 1997-2014

Trends in Obesity Prevalence in Adults With a History of Cancer: Results From the US National Health Interview Survey, 1997 to 2014

Greenlee, Heather ; Shi, Zaixing ; Sardo Molmenti, Christine L. ; Rundle, Andrew ; Tsai, Wei Yann

Purpose : Obesity after a diagnosis of specific cancers has been associated with worse prognosis. We examined the trend in obesity prevalence among cancer survivors in the United States in the past two decades and compared trends with those of adults without a history of cancer. Patients and Methods : This was a population-based nationally representative sample of 538,969 noninstitutionalized US adults 18 to 85 years old with and without a history of cancer who participated in annual [...]

A partir d'une revue systématique de la littérature (9 études), cette étude fait le point sur le stade au diagnostic et les traitements reçus chez des patients atteints de cancer et souffrant de démence

People with dementia: what is known about their experience of cancer treatment and cancer treatment outcomes? A systematic review

Hopkinson, J. B. ; Milton, R. ; King, A. ; Edwards, D.

Objective : The objective of the study is to report a systematic review of what is currently known about the experience of cancer treatment and cancer treatment in adults with dementia. Methods : The analytic plan and inclusion/exclusion criteria were specified in advance of the search process in a protocol. Searches were conducted in MEDLINE, CINAHL, PsycINFO and the Cochrane Library for publications about people with cancer and a pre-existing dementia. Limits were English language; 2000 to [...]

A partir des données 2005-2012 des registres américains des cancers, cette étude évalue l'association entre une infection par le VIH et la mortalité chez des patients atteints d'un lymphome non hodgkinien (11 071 décès)

Contributions of HIV to Non-Hodgkin Lymphoma Mortality Trends in the US

Howlader, Nadia ; Shiels, Meredith S. ; Mariotto, Angela B. ; Engels, Eric A.

Background: The human immunodeficiency virus (HIV) epidemic has strongly influenced non-Hodgkin lymphoma (NHL) incidence in the US general population, but its effects on NHL mortality trends are unknown. Methods: Using SEER cancer registry data, we assessed NHL mortality rates in the US (2005-2012) and mapped NHL deaths to prior incident cases. Data included HIV status at NHL diagnosis. We describe the proportion of NHL deaths linked to an HIV-infected case, for 3 AIDS-defining subtypes [...]

A partir des données portant sur 845 patients atteints d'un carcinome à cellules rénales à haut risque et inclus dans une étude prospective menée dans 14 pays et évaluant le girentuximab comme traitement adjuvant, cette étude évalue l'association entre l'indice de masse corporelle et la survie

Body Mass Index and Survival in a Prospective Randomized Trial of Localized High Risk Renal Cell Carcinoma

Donin, Nicholas M. ; Pantuck, Allan ; Klöpfer, Pia ; Bevan, Paul ; Fall, Barbara ; Said, Jonathan ; Belldegrun, Arie S ; Chamie, Karim

BACKGROUND : The relationship between adiposity and renal cell carcinoma is poorly understood. Prior studies have suggested BMI (body mass index) may be associated with indolent disease. METHODS : We reviewed the clinicopathologic records of 845 patients across 14 countries who were enrolled in a prospective, placebo-controlled study of adjuvant Girentuximab treatment for high-risk renal cell carcinoma. Clinical features analyzed included age, gender, race, BMI, and performance status. BMI was [...]

A partir d'une revue systématique de la littérature (15 études, 8 745 cas), cette méta-analyse évalue l'association entre une obésité ou un surpoids chez des patientes atteintes d'un cancer du sein et le risque de cardiotoxicité liée aux anthracyclines et au trastuzumab

Obesity as a Risk Factor for Anthracyclines and Trastuzumab Cardiotoxicity in Breast Cancer: A Systematic Review and Meta-Analysis

Guenancia, Charles ; Lefebvre, Annick ; Cardinale, Daniela ; Yu, Anthony F. ; Ladoire, Sylvain ; Ghiringhelli, François ; Zeller, Marianne ; Rochette, Luc ; Cottin, Yves ; Vergely, Catherine

Purpose : Patients with metabolic syndrome have a greater risk of cardiovascular disease, although their susceptibility to chemotherapy-induced cardiac disease is not well documented. The aim of this meta-analysis was to assess associations between obesity or being overweight and cardiotoxicity from anthracyclines and sequential anthracyclines and trastuzumab in patients with breast cancer. Methods : We performed a random-effects analysis and a network meta-analysis and assessed publication [...]

Menée à partir des données 2000-2012 des registres américains des cancers incluant 40 264 patients atteints d'un carcinome épidermoïde de l'oropharynx après 65 ans, cette étude compare l'évolution de l'incidence de la maladie avec celle des cancers liés au tabac (larynx, cavité buccale, hypopharynx, poumon) et celle des cancers liés à une infection par le papillomavirus (anus), puis évalue la survie

Incidence of oropharyngeal cancer among elderly patients in the United States

Zumsteg, Z. S. ; Cook-Wiens, G. ; Yoshida, E. ; et al.,

Importance  : An escalating incidence of human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) has been reported predominantly among middle-aged adults. However, HPV infection is believed to occur many years before cancer develops, and tissue studies suggest that HPV DNA is found in the majority of OPSCC diagnosed in patients 65 years or older. Objective : To update the trends in OPSCC incidence using US cancer registry data, with an emphasis on age-specific trends. [...]

Menée en Allemagne auprès de 4 020 patients atteints de cancer, cette étude multicentrique analyse leur utilisation des soins psychologiques (psychothérapie, conseils psychologiques)

Utilization of professional psychological care in a large German sample of cancer patients

Faller, Hermann ; Weis, Joachim ; Koch, Uwe ; Brähler, Elmar ; Härter, Martin ; Keller, Monika ; Schulz, Holger ; Wegscheider, Karl ; Boehncke, Anna ; Hund, Bianca ; Reuter, Katrin ; Richard, Matthias ; Sehner, Susanne ; Wittchen, Hans-Ulrich ; Mehnert, Anja

Objective : Although one-third of cancer patients are perceived to have a need for psychological support based on the percentage of mental disorders, little is known about the actual utilization of psychological care in cancer. We aimed to assess cancer patients' reported use of psychological care and its correlates in a large, representative sample. Methods : In a multicenter, cross-sectional study in Germany, 4020 cancer patients (mean age 58 years, 51% women) were evaluated. We obtained [...]

Menée en Italie auprès de 417 patients atteints d'une leucémie myéloïde chronique recevant des thérapies ciblées (âge moyen : 56 ans), cette étude évalue, en fonction du sexe du patient, l'association entre le soutien social et leur bien-être psychique

Psychological well-being and social support in chronic myeloid leukemia patients receiving lifelong targeted therapies

Efficace, Fabio ; Breccia, Massimo ; Cottone, Francesco ; Okumura, Iris ; Doro, Maribel ; Riccardi, Francesca ; Rosti, Gianantonio ; Baccarani, Michele

Purpose : The main objective of this study was to investigate whether social support is independently associated with psychological well-being in chronic myeloid leukemia (CML) patients. Secondary objectives were to compare the psychological well-being profile of CML patients with that of their peers in general population and to examine possible age- and sex-related differences. Patients and methods : Analysis was performed on 417 patients in treatment with lifelong molecularly targeted [...]

Menée en Angleterre auprès de 8 576 patients de médecins généralistes et éligibles au dépistage du cancer colorectal (45 - 59,5 ans), cette étude analyse les facteurs psychologiques facilitant ou entravant leur participation au dépistage en fonction du niveau d'éducation

Inequalities in cancer screening participation: examining differences in perceived benefits and barriers

Smith, S. G. ; McGregor, L. M. ; Raine, R. ; Wardle, J. ; von Wagner, C. ; Robb, K. A.

Objective : Inequalities exist in colorectal cancer (CRC) screening uptake, with people from lower socioeconomic status backgrounds less likely to participate. Identifying the facilitators and barriers to screening uptake is important to addressing screening disparities. We pooled data from 2 trials to examine educational differences in psychological constructs related to guaiac fecal occult blood testing. Methods : Patients (n = 8576) registered at 7 general practices in England, within [...]

Menée aux Pays-Bas par questionnaire auprès de 460 patientes ayant survécu à un cancer du sein (âge médian: 55,8 ans), cette étude analyse l'efficacité d'un outil permettant d'évaluer la peur de la récidive de la maladie

Towards an evidence-based model of fear of cancer recurrence for breast cancer survivors

Custers, José A. E. ; Gielissen, Marieke F. M. ; de Wilt, Johannes H. W. ; Honkoop, Aafke ; Smilde, Tineke J. ; van Spronsen, Dick-Johan ; van der Veld, William ; van der Graaf, Winette T. A. ; Prins, Judith B.

Purpose : In order to understand the multidimensional mechanism of fear of cancer recurrence (FCR) and to identify potential targets for interventions, it is important to empirically test the theoretical model of FCR. This study aims at assessing the validity of Lee-Jones et al.’s FCR model. Methods : A total of 1205 breast cancer survivors were invited to participate in this study. Participants received a questionnaire booklet including questionnaires on demographics and psychosocial variables [...]

Cette étude présente des recommandations européennes relatives à la prise en charge psychologique des patients atteints d'un cancer de la tête et du cou lié au papillomavirus humain

Best practice guidelines in the psychosocial management of HPV-related head and neck cancer. Recommendations from the European Head and Neck Cancer Society's Make Sense Campaign

Reich, M. ; Licitra, L. ; Vermorken, J. B. ; Bernier, J. ; Parmar, S. ; Golusinski, W. ; Castellsagué, X. ; Leemans, C. R.

Over the past three decades, oral human papillomavirus (HPV) has been associated with an increase in the incidence of oropharyngeal squamous cell carcinoma (OPSCC) in several countries. Specialist oncologists in head and neck cancer are observing a wider range of demographics, sexual behaviours and survival outcomes with their patients. Additionally, there are fewer smokers, consumers of alcohol, or people of lower socioeconomic status than in previous decades. In order to support patients, the [...]

Cette étude analyse les coûts associés aux tumeurs hématologiques dans 28 pays européens pour l'année 2012, qu'il s'agisse des coûts liés à l'utilisation des soins et ressources de santé ou liés aux baisses de productivité induites par des morbidités et une mortalité précoce

Economic burden of malignant blood disorders across Europe: a population-based cost analysis

Burns, Richeal ; Leal, Jose ; Sullivan, Richard ; Luengo-Fernandez, Ramon

Background : Malignant blood disorders are a leading contributor to cancer incidence and mortality across Europe. Despite their burden, no study has assessed the economic effect of blood cancers in Europe. We aimed to assess the economic burden of malignant blood disorders across the 28 countries in the European Union (EU), Iceland, Norway, and Switzerland. Methods : Malignant blood disorder-related costs were estimated for 28 EU countries, Iceland, Norway, and Switzerland for 2012. [...]

Menée aux Etats-Unis, cette étude analyse l'utilisation, pendant le processus de la prise de décision thérapeutique, de moyens de communication en ligne (email, média sociaux, groupes de soutien sur internet...) par des patientes atteintes d'un cancer du sein récemment diagnostiqué, puis évalue l'impact de ces outils sur leur décision

Use of online communication by patients with newly diagnosed breast cancer during the treatment decision process

Wallner, L. P. ; Martinez, K. A. ; Li, Y. ; et al.,

Online communication (including email, social media, and web-based support groups) could be used to enhance cancer treatment decision making and care support. Yet, little is known about whether and how patients with newly diagnosed cancer use these technologies during the treatment decision process and even less is known about whether online communication use influences patient appraisals of decision making. Therefore, we characterized online communication use in a diverse, population-based [...]

Menée en Allemagne auprès de 27 experts pluridisciplinaires, cette étude de consensus présente leurs recommandations de bonnes pratiques relatives à l'intégration des soins palliatifs dans les centres de lutte contre le cancer

Integrating Palliative Care Into Comprehensive Cancer Centers: Consensus-Based Development of Best Practice Recommendations

Berendt, Julia ; Stiel, Stephanie ; Simon, Steffen T. ; Schmitz, Andrea ; van Oorschot, Birgitt ; Stachura, Peter ; Ostgathe, Christoph

Background : International associations admit that specialized palliative care (SPC) is an obvious component of excellent cancer care. Nevertheless, gaps in integration at the international level have been identified. Recommendations for integrating SPC in clinical care, research, and education are needed, which are subject of the present study. Materials and Methods : A Delphi study, with three written Delphi rounds, including a face-to-face-meeting with a multiprofessional expert panel (n = [...]

Mené au Canada par entretiens qualitatifs auprès de 48 patients atteints de cancer et de 23 soignants (oncologues et médecins de soins palliatifs), cet essai randomisé analyse le rôle de chaque catégorie de professionnels de santé dans l'intégration précoce des soins palliatifs en oncologie

Early Palliative Care and Its Role in Oncology: A Qualitative Study

Hannon, Breffni ; Swami, Nadia ; Pope, Ashley ; Leighl, Natasha ; Rodin, Gary ; Krzyzanowska, Monika ; Zimmermann, Camilla

Early integration of palliative care alongside oncology is being increasingly recommended, although the strategies and models for integration remain poorly defined. We solicited the opinions of patients and caregivers who participated in a randomized trial of early palliative care versus standard oncology care, regarding the respective roles of their oncologist (both groups) and palliative care physician (early palliative care group).The study was performed at a comprehensive cancer center. [...]

Menée aux Etats-Unis par enquête auprès de 240 oncologues, cette étude évalue l'association entre leurs attitudes vis-à-vis des soins de fin de vie, le moment où ils orientent leurs patients vers un spécialiste des soins palliatifs, et les décisions relatives aux traitements palliatifs

Impact of Oncologists’ Attitudes Toward End-of-Life Care on Patients’ Access to Palliative Care

Hui, David ; Cerana, Maria Agustina ; Park, Minjeong ; Hess, Kenneth ; Bruera, Eduardo

Background : It is unclear how oncologists’ attitudes toward end-of-life (EOL) care affect the delivery of care. The present study examined the association between oncologists’ EOL care attitudes and (a) timely specialist palliative care referral, (b) provision of supportive care, and (c) EOL cancer treatment decisions. Methods : We randomly surveyed 240 oncology specialists at our tertiary care cancer center to assess their attitudes toward EOL care using a score derived from the Jackson et [...]