A partir des données de la cohorte européenne EPIC, cette étude évalue l'association entre une consommation totale et spécifique de produits laitiers et le risque de carcinome hépatocellulaire

Dairy products and risk of hepatocellular carcinoma: The European Prospective Investigation into Cancer and Nutrition

Duarte-Salles, Talita ; Fedirko, Veronika ; Stepien, Magdalena ; Trichopoulou, Antonia ; Bamia, Christina ; Lagiou, Pagona ; Lukanova, Annekatrin ; Trepo, Elisabeth ; Overvad, Kim ; Tjønneland, Anne ; Halkjær, Jytte ; Boutron-Ruault, Marie-Christine ; Racine, Antoine ; Cadeau, Claire ; Kühn, Tilman ; Aleksandrova, Krasimira ; Trichopoulos, Dimitrios ; Tsiotas, Konstantinos ; Boffetta, Paolo ; Palli, Domenico ; Pala, Valeria ; Tumino, Rosario ; Sacerdote, Carlotta ; Panico, Salvatore ; Bueno-de-Mesquita, H. Bas ; Dik, Vincent K. ; Peeters, Petra H. ; Weiderpass, Elisabete ; Torhild Gram, Inger ; Hjartåker, Anette ; Ramon Quiros, Jose ; Fonseca-Nunes, Ana ; Molina-Montes, Esther ; Dorronsoro, Miren ; Navarro Sanchez, Carmen ; Barricarte, Aurelio ; Lindkvist, Björn ; Sonestedt, Emily ; Johansson, Ingegerd ; Wennberg, Maria ; Khaw, Kay-Tee ; Wareham, Nick ; Travis, Ruth C. ; Romieu, Isabelle ; Riboli, Elio ; Jenab, Mazda

Intake of dairy products has been associated with risk of some cancers, but findings are often inconsistent and information on hepatocellular carcinoma (HCC) risk is limited, particularly from prospective settings. The aim of our study was to investigate the association between consumption of total and specific dairy products (milk/cheese/yogurt) and their components (calcium/vitamin D/fats/protein), with first incident HCC (Ncases = 191) in the European Prospective Investigation into Cancer [...]

A partir des données de la cohorte "Netherlands Cohort Study" incluant 58 279 hommes âgés de 55 à 69 ans, cette étude prospective néerlandaise évalue l'association entre une exposition professionnelle à l'amiante et le rique de cancer de l'œsophage, de l'estomac ou du côlon-rectum

Occupational asbestos exposure and risk of esophageal, gastric and colorectal cancer in the prospective Netherlands Cohort Study

Offermans, Nadine S. M. ; Vermeulen, Roel ; Burdorf, Alex ; Goldbohm, R. Alexandra ; Keszei, András P. ; Peters, Susan ; Kauppinen, Timo ; Kromhout, Hans ; van den Brandt, Piet A.

The evidence for an association between occupational asbestos exposure and esophageal, gastric and colorectal cancer is limited. We studied this association specifically addressing risk differences between relatively low and high exposure, risk associated with cancer subtypes, the influence of potential confounders and the interaction between asbestos and smoking in relation to cancer risk. Using the Netherlands Cohort Study (n = 58,279 men, aged 55–69 years at baseline), asbestos exposure was [...]

A partir d'une revue systématique de la littérature (30 études), cette étude évalue l'association entre diverses expositions professionnelles et le risque de cancer de la thyroïde

Occupation and thyroid cancer

Aschebrook-Kilfoy, Briseis ; Ward, Mary H ; Della Valle, Curt T ; Friesen, Melissa C

Numerous occupational and environmental exposures have been shown to disrupt thyroid hormones, but much less is known about their relationships with thyroid cancer. Here we review the epidemiology studies of occupations and occupational exposures and thyroid cancer incidence to provide insight into preventable risk factors for thyroid cancer. The published literature was searched using the Web of Knowledge database for all articles through August 2013 that had in their text ‘occupation’ ‘job’ [...]

A partir des données de la cohorte "Nurses’ Health Study" incluant 108 578 femmes, cette étude de cohorte évalue l'association entre une exposition cumulée à des rayonnements ultraviolets solaires durant l'âge adulte et le risque de cancer de la peau

Cumulative ultraviolet radiation flux in adulthood and risk of incident skin cancers in women

Wu, S. ; Han, J. ; Vleugels, R. A. ; Puett, R. ; Laden, F. ; Hunter, D. J. ; Qureshi, A. A.

Background: Solar ultraviolet (UV) exposure estimated based on residential history has been used as a sun exposure indicator in previous case–control and descriptive studies. However, the associations of cumulative UV exposure based on residential history with different skin cancers, including melanoma, squamous cell carcinoma (SCC), and basal cell carcinoma (BCC), have not been evaluated simultaneously in prospective studies. Methods: We conducted a cohort study among 108 578 women in the [...]

Menée auprès de 1 069 cas et de 1 107 témoins, cette étude en population américaine évalue l'association entre une infection par divers types de papillomavirus humains et le risque de carcinome épidermoïde de la tête et du cou

High-risk HPV types and head and neck cancer

Michaud, Dominique S. ; Langevin, Scott M. ; Eliot, Melissa ; Nelson, Heather H. ; Pawlita, Michael ; McClean, Michael D. ; Kelsey, Karl T.

Although HPV16 has been strongly implicated in oropharyngeal carcinogenesis, the role of other high-risk HPV types in the etiology of head and neck cancer remains unclear. To date, few data exist addressing the nature of the association between antibodies to oncogenic proteins of non-HPV16 HPVs in relation to head and neck cancer. We examined the relationship between multiple HPV types (HPV6, 11, 16, 18, 31, 33, 45, 52, 58) and head and neck squamous cell carcinoma (HNSCC) in a large [...]

Menée auprès de 147 patientes atteintes d'un lymphome hodgkinien, cette étude évalue l'association entre une radiothérapie et le risque de cancer du sein, en fonction du sous-type histologique

Histologic subtypes of breast cancer following radiotherapy for Hodgkin lymphoma

Horst, K. C. ; Hancock, S. L. ; Ognibene, G. ; Chen, C. ; Advani, R. H. ; Rosenberg, S. A. ; Donaldson, S. S. ; Hoppe, R. T.

Background : The purpose of the study was to determine whether breast cancers (BCs) that develop in women previously irradiated for Hodgkin lymphoma (HL) are biologically similar to sporadic BC. Materials and methods : We retrospectively reviewed the charts of patients who developed BC after radiotherapy (RT) for HL. Tumors were classified as ductal carcinoma in situ (DCIS) or invasive carcinoma. Invasive carcinomas were further characterized according to the subtype: hormone receptor [...]

A partir des données de la cohorte prospective "Shanghai Women's and Men's Health Studies" incluant 133 014 participants et d'une revue d'études observationnelles, cette méta-analyse évalue l'association entre une histoire familiale de cancer du foie et le risque de développer la maladie

Prospective cohort studies of association between family history of liver cancer and risk of liver cancer

Yang, Yang ; Wu, Qi-Jun ; Xie, Li ; Chow, Wong-Ho ; Rothman, Nat ; Li, Hong-Lan ; Gao, Yu-Tang ; Zheng, Wei ; Shu, Xiao-Ou ; Xiang, Yong-Bing

Uncertainty remains on the relationship between a family history of liver cancer and liver cancer risk in prospective cohort studies in a general population. Thus, we examined this association in 133,014 participants in the Shanghai Women's and Men's Health Studies. Family history of liver cancer was categorized through dichotomous and proportional score approaches. Hazard ratios (HRs) and 95% confidence intervals (CIs) were derived using the Cox proportional hazards models with adjustment for [...]

A partir des données des registres américains des cancers portant sur 1,2 million de cas et 200 000 témoins (âgé de 66 à 99 ans sur la période 1992-2005), cette étude évalue l'association entre une maladie thromboembolique veineuse et le risque ultérieur de cancer

Venous Thromboembolism and Cancer Risk among Elderly Adults in the U.S

Marks, Morgan A. ; Engels, Eric A.

Background: Few studies have evaluated cancer risk following venous thromboembolism (VTE). Both VTE and cancer disproportionately affect older adults. Methods: Using linked Surveillance, Epidemiology, and End Results (SEER)-Medicare data, we evaluated 1.2 million cancer cases and 200,000 controls (66-99 years old, 1992-2005). VTEs occurring before selection were identified using Medicare claims. Logistic regression was used to estimate odds ratios (ORs). Results: VTE was present in 2.5% of [...]

A partir des données des registres américains des cancers portant sur la période 1992-2009, cette étude analyse l'association entre un mélanome et le risque subséquent de gliome

Exploring the association between melanoma and glioma risks

Scarbrough, Peter M. ; Akushevich, Igor

Purpose : Gliomas are one of the most fatal malignancies, with largely unknown etiology. This study examines a possible connection between glioma and melanoma, which might provide insight into gliomas’ etiology. Methods :Using data provided by the Surveillance, Epidemiology, and End Results (SEER) program from 1992-2009, a cohort was constructed to determine the incidence rates of glioma among those who had a prior diagnosis of invasive melanoma. Glioma rates in those with prior melanoma were [...]

A partir d'une revue systématique de la littérature (21 études de cohorte, 9 080 052 participants, 15 144 cas de cancer), cette méta-analyse évalue l'association entre l'indice de masse corporelle et le risque de cancer à cellules rénales

Body mass index and risk of renal cell cancer: A dose-response meta-analysis of published cohort studies

Wang, Furan ; Xu, Yinghua

Obesity is accepted as one of the major risk factors for renal cell cancer (RCC). However, conflicting results persist for the pooled risks based on the results from case–control and cohort studies combined, and the exact shape of the dose–response relationship has not been clearly defined yet. To help elucidate the role of obesity, PubMed and Embase databases were searched for published cohort studies on associations between body mass index (BMI) and risk of RCC. Random-effects models and [...]