A partir d'une revue systématique de la littérature (18 études), cette étude fait le point sur les besoins de nature psychosociale non satisfaits chez des patients adultes atteints d'un cancer hématologique

Unmet psychosocial needs in haematological cancer: a systematic review

Swash, B. ; Hulbert-Williams, N. ; Bramwell, R.

Purpose : Psychosocial need implies a desire or requirement for support that underlies a person’s psychological, social and emotional wellbeing. This is not a new concept in the wider cancer literature, yet remains a relatively unexplored area in relation to haematological malignancies. The well-recognised differences between haematological and other types of cancer diagnosis warrant further investigation to try and highlight the potential differences in the needs of this patient group. Method [...]

A partir d'une revue systématique de la littérature (17 études), cette étude analyse les effets à long terme de l'acupuncture sur les bouffées de chaleur de patientes atteintes d'un cancer du sein et de patients atteints d'un cancer de la prostate

How long do the effects of acupuncture on hot flashes persist in cancer patients?

Frisk, JessicaW ; Hammar, MatsL ; Ingvar, Martin ; Spetz Holm, Anna-ClaraE

Purpose : Acupuncture has been suggested as therapy for hot flashes in women with breast cancer and men with prostate cancer. In this systematic review, we sought to evaluate the long-term effects on vasomotor symptoms after the end of a defined treatment period of acupuncture in women with breast cancer and men with prostate cancer. Methods : A literature search revealed 222 articles within the field. With defined exclusion criteria, we identified 17 studies. We also used the Jadad quality [...]

Menée aux Etats-Unis auprès de 104 survivantes à un an d'un cancer du col de l'utérus ou de l'endomètre, cette étude analyse la prévalence et la sévérité de symptômes au niveau de la vessie ou de l'intestin

Bladder and bowel symptoms in cervical and endometrial cancer survivors

Donovan, Kristine A. ; Boyington, Alice R. ; Judson, Patricia L. ; Wyman, Jean F.

Background : Previous studies likely underestimate the prevalence of bowel and bladder symptoms in gynecologic cancer survivors. We sought to estimate the prevalence of these symptoms in cervical and endometrial cancer survivors who had completed treatment 1 year previously compared with non-cancer controls, and to examine factors associated with more severe symptoms in survivors. Methods : As part of a larger quality of life study, survivors who were 1-year posttreatment for cervical or [...]

A partir d'une revue systématique de la littérature (47 études), cette méta-analyse évalue les effets d'interventions visant à prévenir ou traiter les réactions cutanées induites par les rayonnements chez des patients atteints de cancer

Prevention and treatment of acute radiation-induced skin reactions: a systematic review and meta-analysis of randomized controlled trials

Chan, Raymond ; Webster, Joan ; Chung, Bryan ; Marquart, Louise ; Ahmed, Muhtashimuddin ; Garantziotis, Stuart

BACKGROUND:Radiation-induced skin reaction (RISR) is a common side effect that affects the majority of cancer patients receiving radiation treatment. RISR is often characterised by swelling, redness, pigmentation, fibrosis, and ulceration, pain, warmth, burning, and itching of the skin. The aim of this systematic review was to assess the effects of interventions which aim to prevent or manage RISR in people with cancer. METHODS:We searched the following databases up to November 2012: Cochrane [...]

Menée aux Etats-Unis par questionnaire auprès de 1 109 patients atteints d'un cancer colorectal et traités dans le système de santé des anciens combattants, cette étude analyse leurs points de vue relatifs à la qualité des soins de support destinés à prendre en charge leurs problèmes intestinaux, la douleur, la fatigue, la dépression et autres symptômes associés à la maladie

Patient-Reported Quality of Supportive Care Among Patients With Colorectal Cancer in the Veterans Affairs Health Care System

van Ryn, Michelle ; Phelan, Sean M. ; Arora, Neeraj K. ; Haggstrom, David A. ; Jackson, George L. ; Zafar, S. Yousuf ; Griffin, Joan M. ; Zullig, Leah L. ; Provenzale, Dawn ; Yeazel, Mark W. ; Jindal, Rahul M. ; Clauser, Steven B.

Purpose : High-quality supportive care is an essential component of comprehensive cancer care. We implemented a patient-centered quality of cancer care survey to examine and identify predictors of quality of supportive care for bowel problems, pain, fatigue, depression, and other symptoms among 1,109 patients with colorectal cancer. Patients and Methods : Patients with new diagnosis of colorectal cancer at any Veterans Health Administration medical center nationwide in 2008 were ascertained [...]

Menée au Canada par enquête en ligne auprès de 102 patientes atteintes d'un cancer du sein (âge moyen : 54 ans), cette étude transversale analyse leurs préférences relatives aux différents protocoles de chimiothérapie et à leurs effets indésirables

Use of Conjoint Analysis to Assess Breast Cancer Patient Preferences for Chemotherapy Side Effects

Beusterien, Kathleen ; Grinspan, Jessica ; Kuchuk, Iryna ; Mazzarello, Sasha ; Dent, Susan ; Gertler, Stan ; Bouganim, Nathaniel ; Vandermeer, Lisa ; Clemons, Mark

Objective : Our objective was to evaluate preferences associated with grade I/II and grade III/IV chemotherapy side effects among breast cancer patients receiving chemotherapy. We also assessed trade-offs that patients are willing to make between treatment side effects and the route and schedule of treatment administration. Methods : In this cross-sectional study, patients receiving chemotherapy for breast cancer completed a one-time Web survey. Conjoint analysis was used to elicit preferences [...]

Menée au Royaume-Uni auprès de 28 477 patients atteints de cancer et âgés de plus de 15 ans lors du diagnostic, cette étude de cohorte évalue l'association entre des troubles psychiatriques, le stade du cancer au diagnostic et la survie

A cohort study on mental disorders, stage of cancer at diagnosis and subsequent survival

Chang, Chin-Kuo ; Hayes, Richard D ; Broadbent, Matthew T M ; Hotopf, Matthew ; Davies, Elizabeth ; Møller, Henrik ; Stewart, Robert

Objectives : To assess the stage at cancer diagnosis and survival after cancer diagnosis among people served by secondary mental health services, compared with other local people.Setting Using the anonymised linkage between a regional monopoly secondary mental health service provider in southeast London of four London boroughs, Croydon, Lambeth, Lewisham and Southwark, and a population-based cancer register, a historical cohort study was constructed. Participants : A total of 28 477 cancer [...]

A partir du registre national des cancers portant sur 3 858 patients atteints d'un lymphome diffus à grandes cellules B et âgés de 18 à 64 ans, cette étude américaine analyse l'association entre la couverture médicale du patient et la survie

Insurance status is related to diffuse large B-cell lymphoma survival

Han, Xuesong ; Jemal, Ahmedin ; Flowers, Christopher R. ; Sineshaw, Helmneh ; Nastoupil, Loretta J. ; Ward, Elizabeth

BACKGROUND Insurance status is associated with stage at diagnosis and treatment for non-Hodgkin lymphoma (NHL), but no previous studies have addressed the relation between insurance status and survival for patients diagnosed with diffuse large B-cell lymphoma (DLBCL), the most common subtype of NHL. METHODS The authors analyzed survival among 3858 patients with DLBCL ages 18 to 64 years who were diagnosed in 2004 using data from the National Cancer Database, a nationwide, hospital-based cancer [...]

A partir des données du registre californien des cancers portant sur 35 427 hommes d'origine hispanique, cette étude américaine analyse l'association entre le lieu de naissance, le statut socioéconomique du lieu de résidence et la survie de patients atteints d'un cancer invasif de la prostate diagnostiqué entre 1995 et 2008

Immigration factors and prostate cancer survival among Hispanic men in California: Does neighborhood matter?

Schupp, Clayton W. ; Press, David J. ; Gomez, Scarlett Lin

BACKGROUND Hispanics are more likely than other racial/ethnic groups in the United States to be diagnosed with later stage of prostate cancer, yet they have lower prostate cancer mortality rates. The authors evaluated the impact of nativity and neighborhood-level Hispanic ethnic enclave on prostate cancer survival among Hispanics. METHODS A total of 35,427 Hispanic men diagnosed with invasive prostate cancer from 1995 through 2008 in the California Cancer Registry were studied; vital status [...]

A partir des données des registres américains portant sur des patients atteints d'un cancer rectal de type T3N0 diagnostiqué entre 1998 et 2008, cette étude analyse l'association entre une radiothérapie pré et post-opératoire et la survie

Surveillance, Epidemiology, and End Results-based analysis of the impact of preoperative or postoperative radiotherapy on survival outcomes for T3N0 rectal cancer

Luke C. Penga ; Jeffrey Milsomb ; Kelly Garrettb ; Govind Nandakumarb ; Shana Coplowitza ; Bhupesh Parashara ; Dattatreyudu Noria ; K.S. Clifford Chaoa ; A.G. Wernicke

Purpose: Preoperative chemoradiation has been established as standard of care for T3/T4 node-positive rectal cancer. Recent work, however, has called into question the overall benefit of radiation for tumors with lower risk characteristics, particularly T3N0 rectal cancers. We retrospectively analyzed T3N0 rectal cancer patients and examined how outcomes differed according to the sequence of treatment received. Methods: The Surveillance, Epidemiology, and End Results (SEER) database was used to [...]

Menée aux Etats-Unis auprès de 2 318 patients atteints d'un carcinome non métastatique à cellules rénales, cette étude analyse l'impact d'une transfusion sanguine périopératoire sur la survie des patients après une néphrectomie

The impact of perioperative blood transfusion on survival after nephrectomy for non-metastatic renal cell carcinoma (RCC)

Linder, Brian J. ; Thompson, R. Houston ; Leibovich, Bradley C. ; Cheville, John C. ; Lohse, Christine M. ; Gastineau, Dennis A. ; Boorjian, Stephen A.

Objective : To evaluate the association of perioperative blood transfusion (PBT) with survival after nephrectomy. and Methods : We identified 2318 patients who underwent partial or radical nephrectomy at Mayo Clinic between 1990 and 2006. * PBT was defined as transfusion of allogenic red blood cells during surgery or postoperative hospitalisation. * Survival was estimated using the Kaplan–Meier method and compared with the log-rank test. Cox proportional hazards regression models were used to [...]

A partir des données de deux registres suisses des cancers portant sur la période 1976-2010, cette étude analyse l'incidence d'un deuxième cancer primitif de type sarcome et identifie des facteurs de risque associés

Incidence of second sarcomas: a cancer registry-based study

Levi, Fabio ; Randimbison, Lalao ; Maspoli-Conconi, Manuela ; Blanc-Moya, Rafael ; Vecchia, Carlo

Background : In high-quality cancer registration systems, about one in eight incident cancers are second primary cancers. This is due to a combination of careful diagnostic ascertainment, shared genetic determinants, shared exposure to environmental factors and consequences of treatment for first cancer. Methods : We used data derived from the Swiss population-based cancer Registries of Vaud and Neuchâtel, including 885,000 inhabitants. Results : Among 107,238 (52% males) first cancers [...]

Menée auprès de 6 827 patientes atteintes d'un cancer du sein de stade I à III diagnostiqué entre 1997 et 2011, cette étude américaine analyse l'association entre la durée de la période précédant le début d'une chimiothérapie adjuvante et la survie des patientes, en fonction du sous-type de cancer et du stade au diagnostic

Clinical Impact of Delaying Initiation of Adjuvant Chemotherapy in Patients With Breast Cancer

de Melo Gagliato, Debora ; Gonzalez-Angulo, Ana M. ; Lei, Xiudong ; Theriault, Richard L. ; Giordano, Sharon H. ; Valero, Vicente ; Hortobagyi, Gabriel N. ; Chavez-MacGregor, Mariana

Purpose : For patients with breast cancer (BC), the optimal time to initiation of adjuvant chemotherapy (TTC) after definitive surgery is unknown. We evaluated the association between TTC and survival according to breast cancer subtype and stage at diagnosis. Patients and Methods : Women diagnosed with BC stages I to III between 1997 and 2011 who received adjuvant chemotherapy at our institution were included. Patients were categorized into three groups according to TTC: ≤ 30, 31 to 60, and ≥ [...]

Menée auprès de 1 863 adultes survivants d'un cancer de l'enfance (âge moyen : 32 ans), cette étude américaine analyse la prévalence de symptômes de détresse et leur association avec les effets indésirables à long terme de la maladie et de ses traitements

Emotional distress among adult survivors of childhood cancer

Oancea, S. Cristina ; Brinkman, TaraM ; Ness, KirstenK ; Krull, KevinR ; Smith, WebbA ; Srivastava, D. Kumar ; Robison, LeslieL ; Hudson, MelissaM ; Gurney, JamesG

Purpose : The purposes of this study were to estimate the prevalence of emotional distress in a large cohort of adult survivors of childhood cancer and to evaluate the interrelationship of risk factors including cancer-related late effects. Methods : Adult survivors of childhood cancer (N=1,863), median age of 32 years at follow-up, completed comprehensive medical evaluations. Clinically relevant emotional distress was assessed using the Brief Symptom Inventory 18 and was defined as T-scores [...]

Menée auprès de 1 525 survivants d'un cancer, cette étude américaine transversale analyse leurs expériences lors du retour à l'emploi, en fonction de leurs symptômes, leurs déficiences physiques et leur environnement professionnel

Function and friction at work: a multidimensional analysis of work outcomes in cancer survivors

Moskowitz, MichalC ; Todd, BrianaL ; Chen, Rusan ; Feuerstein, Michael

Objectives : Cancer survivors can experience difficulties returning to and/or remaining at work. Sociodemographic, health and well-being, symptom burden, functional limitations in relation to work demands, work environment, and various work policies and procedures can be related to work function. Methods : This study analyzed cross-sectional data of a sample of cancer survivors (n=1,525) who were diagnosed and treated for various types of cancer. The data were obtained from a survey of cancer [...]

Menée aux Etats-Unis auprès de 1 522 survivants à long terme d'un cancer (4 à 14 ans après le diagnostic), cette étude transversale analyse les facteurs sociodémographiques et cliniques associés à leur sentiment d'auto-efficacité pour prendre part à la décision relative aux soins de suivi, à leurs besoins et à leur utilisation des soins de support

Social support, self-efficacy for decision-making, and follow-up care use in long-term cancer survivors

Forsythe, Laura P. ; Alfano, Catherine M. ; Kent, Erin E. ; Weaver, Kathryn E. ; Bellizzi, Keith ; Arora, Neeraj ; Aziz, Noreen ; Keel, Gretchen ; Rowland, Julia H.

Objective : Cancer survivors play an important role in coordinating their follow-up care and making treatment-related decisions. Little is known about how modifiable factors such as social support are associated with active participation in follow-up care. This study tests associations between social support, cancer-related follow-up care use, and self-efficacy for participation in decision-making related to follow-up care (SEDM). We also identified sociodemographic and clinical factors [...]

Menée aux Etats-Unis auprès de 159 enfants atteints d'une leucémie lymphoblastique aiguë (âge : de 2 à 10 ans), cette étude de cohorte prospective analyse la prévalence de symptômes d'anxiété et de dépression ainsi que des changements comportementaux durant l'année suivant le diagnostic de cancer

A prospective study of anxiety, depression, and behavioral changes in the first year after a diagnosis of childhood acute lymphoblastic leukemia

Myers, Regina M. ; Balsamo, Lyn ; Lu, Xiaomin ; Devidas, Meenakshi ; Hunger, Stephen P. ; Carroll, William L. ; Winick, Naomi J. ; Maloney, Kelly W. ; Kadan-Lottick, Nina S.

BACKGROUND The authors prospectively assessed anxiety, depression, and behavior in children with standard-risk acute lymphoblastic leukemia (SR-ALL) during the first year of therapy and identified associated risk factors. METHODS A cohort study was performed of 159 children (aged 2 years-9.99 years) with SR-ALL who were enrolled on Children's Oncology Group protocol AALL0331 at 31 sites. Parents completed the Behavior Assessment System for Children, the General Functioning Scale of the Family [...]

Menée auprès de 16 couples où la femme est atteinte d'un cancer du sein, cette étude qualitative canadienne analyse la faisabilité et l'efficacité d'une intervention en ligne destinée à aider les couples à faire face à la maladie

Development and pilot testing of an online intervention to support young couples' coping and adjustment to breast cancer

Fergus, K. D. ; McLeod, D. ; Carter, W. ; Warner, E. ; Gardner, S. L. ; Granek, L. ; Cullen, K. I.

Couplelinks is an original, professionally facilitated online intervention tailored to the unique challenges facing young women with breast cancer and their male partners. The purpose of this evaluation was to determine the feasibility and acceptability of the intervention and areas for improvement. Sixteen couples were sequentially enrolled over an 18-month period. Couples provided feedback via a treatment satisfaction survey, and post-treatment interviews with a sub-group of participants. [...]

Menée en Irlande auprès de 32 patients atteints de cancer (âge moyen : 58,8 ans), cette étude de cohorte prospective analyse les coûts associés aux soins et traitements de la neutropénie fébrile

The cost of the inpatient management of febrile neutropenia in cancer patients – a micro-costing study in the Irish healthcare setting

O'Brien, C. ; Fogarty, E. ; Walsh, C. ; Dempsey, O. ; Barry, M. ; Kennedy, M. J. ; McCullagh, L.

The objective was to evaluate the resource use and cost of hospitalisation for febrile neutropenia (FN) from the health-payer's perspective. This was a single centre study. Adults undergoing chemotherapy, who were admitted for FN, were identified prospectively. Patient medical records were reviewed retrospectively. Demographics and resource utilisation data were obtained from a cohort of 32 patients (69% female, mean age = 58.8 years). Twenty-five per cent of patients had more than one FN [...]

Menée à partir des données des registres américains des cancers portant sur des survivants d'un cancer thyroïdien différencié diagnostiqué entre 1985 et 2013, cette étude de cohorte analyse les coûts associés aux soins

Annual financial impact of well-differentiated thyroid cancer care in the United States

Lubitz, Carrie C. ; Kong, Chung Y. ; McMahon, Pamela M. ; Daniels, Gilbert H. ; Chen, Yufei ; Economopoulos, Konstantinos P. ; Gazelle, G. Scott ; Weinstein, Milton C.

BACKGROUND Well-differentiated thyroid cancer (WDTC) is a prevalent disease, which is increasing in incidence faster than any other cancer. Substantial direct medical care costs are related to the diagnosis and treatment of newly diagnosed patients as well as the ongoing surveillance of patients who have a long life expectancy. Prior analyses of the aggregate health care costs attributable to WDTC in the United States have not been reported. METHODS A stacked cohort cost analysis was performed [...]

Menée aux Etats-Unis par enquête en ligne, cette étude analyse la communication entre le médecin et ses patients atteints d'un cancer du sein, de la prostate ou d'un myélome multiple au sujet du risque de métatastases osseuses et d'ostéoporose associées aux traitements anti-cancéreux

Awareness, concern, and communication between physicians and patients on bone health in cancer

Tripathy, Debu ; Durie, BrianG M. ; Mautner, Beatrice ; Ferenz, KragS ; Moul, JuddW

Purpose : This study aims to explore physician–patient communications about bone metastases and cancer treatment-induced bone loss (CTIBL). Methods : The study utilizes online survey of patients with breast cancer, prostate cancer, and multiple myeloma, and the physicians who treat them. Results : Even though 69 and 48 % of patients with nonmetastatic breast and prostate cancer aware of treatment-induced bone loss, only 39 and 23 %, respectively, were concerned about bone loss. Yet, 62 and 71 % [...]