Cet article présente les recommandations du National Cancer Institute relatives aux pistes de recherche prioritaires pour prendre en charge la fatigue des patients pédiatriques et adultes atteints de cancer

Recommendations for High-Priority Research on Cancer-Related Fatigue in Children and Adults

Barsevick, Andrea M. ; Irwin, Michael R. ; Hinds, Pamela ; Miller, Andrew ; Berger, Ann ; Jacobsen, Paul ; Ancoli-Israel, Sonia ; Reeve, Bryce B. ; Mustian, Karen ; O’Mara, Ann ; Lai, Jin-Shei ; Fisch, Michael ; Cella, David

Over the past decades, some scientific progress has been made in understanding and treating cancer-related fatigue (CRF). However, three major problems have limited further progress: lack of agreement about measurement, inadequate understanding of the underlying biology, and problems in the conduct of clinical trials for CRF. This commentary reports the recommendations of a National Cancer Institute Clinical Trials Planning Meeting and an ongoing National Cancer Institute working group to [...]

Menée aux Etats-Unis auprès de 550 cas et de 6 643 témoins, cette étude analyse la prévalence de fractures osseuses et d'ostéoporose chez des survivantes d'un cancer du sein ainsi que l'information communiquée par les médecins à ce sujet

Bone health issues in breast cancer survivors: a Medicare Current Beneficiary Survey (MCBS) study

Peppone, LukeJ ; Mustian, KarenM ; Rosier, RandyN ; Carroll, JenniferK ; Purnell, JasonQ ; Janelsins, MichelleC ; Morrow, GaryR ; Mohile, SupriyaG

Purpose : Breast cancer treatments (chemotherapy and hormone therapy) can cause a rapid loss in bone mineral density, leading to osteoporosis and fractures later in life. Fortunately, preventative measures (vitamin D, exercise, etc.) can delay bone loss if employed early enough. This study compares the prevalence of osteoporosis and osteoporosis-related discussions with physicians among female breast cancer survivors and females with no cancer history to determine if breast cancer patients are [...]

Menée par enquête internet auprès de 475 participantes (âge moyen : 54 ans), cette étude analyse les préférences de survivantes d'un cancer du sein afro-américaines relatives à la pratique d'une activité physique

African-American breast cancer survivors’ preferences for various types of physical activity interventions: a Sisters Network Inc. web-based survey

Paxton, RaheemJ ; Nayak, Pratibha ; Taylor, WendellC ; Chang, Shine ; Courneya, KerryS ; Schover, Leslie ; Hodges, Kelly ; Jones, LovellA

Background : Needs assessments are essential to developing lifestyle interventions for minority populations. To our knowledge, no physical activity (PA) needs assessment studies have been conducted for African-American (AA) breast cancer survivors. The purpose of this study was to determine the PA intervention preferences of AA breast cancer survivors and determine whether these preferences differ according to medical and sociodemographic factors. Methods : AA breast cancer survivors (n=475, [...]

Menée en Espagne auprès de 30 survivantes d'un cancer du sein, cette étude descriptive analyse leurs préférences concernant les modalités des soins de réadaptation pour un lymphœdème, à distance par internet ou en face-à-face avec les soignants

Agreement between telerehabilitation involving caregivers and face-to-face clinical assessment of lymphedema in breast cancer survivors

Galiano-Castillo, N. ; Ariza-García, A. ; Cantarero-Villanueva, I. ; Férnandez-Lao, C. ; Sánchez-Salado, C. ; Arroyo-Morales, M.

Lymphedema is a lifetime complication of breast cancer survivors that can limit their participation in recreational or strenuous daily activities. Follow-up of lymphedema using an Internet application could help patients to determine the influence on their condition of these activities and adapt them accordingly. We aimed to determine the level of agreement between lymphedema assessment by telerehabilitation and by the traditional face-to-face method. Thirty breast cancer survivors participated [...]

A partir des données des registres américains des cancers portant sur 25 531 cas, cette étude de cohorte présente les données épidémiologiques et les données de survie des patients atteints d'une tumeur carcinoïde gastrointestinale, sur la période 1973-2009

Gastrointestinal carcinoid: epidemiological and survival evidence from a large population-based study (n = 25 531)

Mocellin, S. ; Nitti, D.

Background: Owing to its rarity, the published evidence on gastrointestinal (GI) carcinoid is often based on small series of patients or population-based studies regarding all neuroendocrine tumors. Here, we present a comprehensive epidemiological and survival analysis of the largest cohort of patients with GI carcinoid ever reported. Patients and methods : Patients with histological diagnosis of GI carcinoid (n = 25 531) were identified from the Surveillance Epidemiology End Results (SEER) [...]

Menée auprès de 806 participants, cette étude de cohorte prospective conduite de 2010 à 2011 évalue l'efficacité clinique du vaccin contre la grippe saisonnière chez des patients atteints de cancer et son impact sur la mortalité

Clinical effectiveness of seasonal influenza vaccine among adult cancer patients

Vinograd, Inbal ; Eliakim-Raz, Noa ; Farbman, Laura ; Baslo, Rina ; Taha, Ahmed ; Sakhnini, Ali ; Lador, Adi ; Stemmer, Salomon M. ; Gafter-Gvili, Anat ; Leibovici, Leonard ; Paul, Mical

BACKGROUND Patients with cancer are at increased risk of developing complications of influenza. In this study, the authors assessed the effectiveness of influenza vaccination among cancer patients. METHODS A prospective, noninterventional cohort study was conducted during the 2010 to 2011 influenza season. The cohort included adult cancer patients with solid malignancies who were receiving chemotherapy and hematologic patients who had active disease. Patients who died between October and [...]

Menée en Angleterre sur la période 2006-2008, cette étude analyse le taux de mortalité à court terme chez les patients dont le cancer a été diagnostiqué à l'occasion d'une hospitalisation en urgence

Emergency presentation of cancer and short-term mortality

McPhail, S. ; Elliss-Brookes, L. ; Shelton, J. ; Ives, A. ; Greenslade, M. ; Vernon, S. ; Morris, E. J. A. ; Richards, M.

Background: The short-term survival following a cancer diagnosis in England is lower than that in comparable countries, with the difference in excess mortality primarily occurring in the months immediately after diagnosis. We assess the impact of emergency presentation (EP) on the excess mortality in England over the course of the year following diagnosis. Methods: All colorectal and cervical cancers presenting in England and all breast, lung, and prostate cancers in the East of England in [...]

A partir des données de la cohorte "Women's Health Initiative" incluant 158 833 participantes sur la période 1993-2009, cette étude américaine analyse et compare la mortalité, toutes causes confondues et par cancer, chez les femmes ménopausées avec ou sans diabète, en fonction de leur appartenance ethnique

All-Cause, Cardiovascular, and Cancer Mortality Rates in Postmenopausal White, Black, Hispanic, and Asian Women With and Without Diabetes in the United States: The Women's Health Initiative, 1993–2009

Ma, Yunsheng ; Hebert, James R. ; Balasubramanian, Raji ; Wedick, Nicole M. ; Howard, Barbara V. ; Rosal, Milagros C. ; Liu, Simin ; Bird, Chloe E. ; Olendzki, Barbara C. ; Ockene, Judith K. ; Wactawski-Wende, Jean ; Phillips, Lawrence S. ; LaMonte, Michael J. ; Schneider, Kristin L. ; Garcia, Lorena ; Ockene, Ira S. ; Merriam, Philip A. ; Sepavich, Deidre M. ; Mackey, Rachel H. ; Johnson, Karen C. ; Manson, JoAnn E.

Using data from the Women's Health Initiative (1993–2009; n = 158,833 participants, of whom 84.1% were white, 9.2% were black, 4.1% were Hispanic, and 2.6% were Asian), we compared all-cause, cardiovascular, and cancer mortality rates in white, black, Hispanic, and Asian postmenopausal women with and without diabetes. Cox proportional hazard models were used for the comparison from which hazard ratios and 95% confidence intervals were computed. Within each racial/ethnic subgroup, women with [...]

A partir de données portant sur 1 840 patients inclus dans des essais cliniques, cette étude analyse la survie des patients adolescents et jeunes adultes atteints de leucémie myéloïde aiguë et la compare avec celle de patients plus jeunes

Differences in outcomes of newly diagnosed acute myeloid leukemia for adolescent/young adult and younger patients

Canner, Jason ; Alonzo, Todd A. ; Franklin, Janet ; Freyer, David R. ; Gamis, Alan ; Gerbing, Robert B. ; Lange, Beverly J. ; Meshinchi, Soheil ; Woods, William G. ; Perentesis, John ; Horan, John

BACKGROUND Studies comparing survival of adolescent and young adult (AYA) patients to that of younger patients with newly diagnosed acute myeloid leukemia (AML) have yielded conflicting results. In order to more accurately characterize relative survival and other outcomes of AYA patients, a cross-study analysis was conducted using data from recent trials conducted by the Children's Cancer Group (CCG) and Children's Oncology Group (COG). METHODS Data were combined from the CCG-2891, CCG-2941, [...]

Menée à partir de données portant sur 2 968 anciens combattants américains, cette étude de cohorte rétrospective évalue l'association entre l'indice de masse corporelle et la survie des patients atteints de myélome multiple

Influence of Body Mass Index on Survival in Veterans With Multiple Myeloma

Beason, Tracey S. ; Chang, Su-Hsin ; Sanfilippo, Kristen M. ; Luo, Suhong ; Colditz, Graham A. ; Vij, Ravi ; Tomasson, Michael H. ; DiPersio, John F. ; Stockerl-Goldstein, Keith ; Ganti, Arun ; Wildes, Tanya ; Carson, Kenneth R.

Purpose.: We investigated the association between body mass index (BMI) at the time of multiple myeloma (MM) diagnosis and overall survival in a cohort of patients within the Veterans Health Administration system. We also evaluated the association between weight loss in the year prior to diagnosis and survival. Patients and Methods : Prospective analysis was performed on a retrospectively assembled cohort of 2,968 U.S. veterans diagnosed and treated for MM between September 1, 1999, and [...]

Menée en Angleterre auprès de 120 745 participants, cette étude de cohorte analyse l'évolution de la survie des patients atteints d'un cancer du poumon non à petites cellules entre 2004 et 2010

Lung cancer survival in England: trends in non-small-cell lung cancer survival over the duration of the National Lung Cancer Audit

Khakwani, A. ; Rich, A. L. ; Powell, H. A. ; Tata, L. J. ; Stanley, R. A. ; Baldwin, D. R. ; Duffy, J. P. ; Hubbard, R. B.

Background: In comparison with other European and North American countries, England has poor survival figures for lung cancer. Our aim was to evaluate the changes in survival since the introduction of the National Lung Cancer Audit (NLCA). Methods: We used data from the NLCA to identify people with non-small-cell lung cancer (NSCLC) and stratified people according to their performance status (PS) and clinical stage. Using Cox regression, we calculated hazard ratios (HRs) for death according to [...]

Couplée à une cohorte de 4 794 patients atteints d'un cancer colorectal diagnostiqué entre 1998 et 2007, cette étude britannique cas-témoins (5 témoins pour 1 cas) analyse l'association entre l'utilisation de bêta-bloquants et la mortalité par cancer colorectal

β-Blocker usage and colorectal cancer mortality: a nested case–control study in the UK Clinical Practice Research Datalink cohort

Hicks, B. M. ; Murray, L. J. ; Powe, D. G. ; Hughes, C. M. ; Cardwell, C. R.

Background : Epidemiological and laboratory studies suggest that β-blockers may reduce cancer progression in various cancer sites. The aim of this study was to conduct the first epidemiological investigation of the effect of post-diagnostic β-blocker usage on colorectal cancer-specific mortality in a large population-based colorectal cancer patient cohort. Patients and methods: A nested case–control analysis was conducted within a cohort of 4794 colorectal cancer patients diagnosed between 1998 [...]

Couplée avec les données des registres nationaux, cette étude de cohorte en population danoise évalue l'association entre un infarctus aigu du myocarde, un accident vasculaire cérébral et le risque de cancer colorectal, sur la période 1978-2010

Risk of colorectal cancer in patients with acute myocardial infarction and stroke: A nationwide cohort study

Erichsen, Rune ; Sværke, Claus ; Sorensen, Henrik Toft ; Sandler, Robert S. ; Baron, John

Background: An association between colorectal cancer (CRC) and acute myocardial infarction (AMI) and stroke has been suggested, but evidence is conflicting. Method: We conducted a population-based cohort study (1978-2010) of the association between AMI/stroke and CRC by linking nationwide Danish registries. We calculated standardized incidence ratios (SIRs) of CRC after AMI/stroke as the ratios of observed to expected incidence. Results: 297,523 AMI patients (median age 69.4, 64% men) were [...]

A partir de données recueillies en Australie au cours des 23 dernières années, cette méta-analyse évalue les facteurs de risque associés à diverses morbidités chez 261 survivants à long terme d'un méningiome diagnostiqué pendant l'enfance ou l'adolescence

Morbidity in survivors of child and adolescent meningioma

Kotecha, Rishi S. ; Jacoby, Peter ; Cole, Catherine H. ; Gottardo, Nicholas G.

BACKGROUND The extent of initial surgical resection has been identified as the strongest prognostic indicator for survival in child and adolescent meningioma. Given the paucity of data concerning long-term outcome, the authors undertook a meta-analysis to analyze morbidity in survivors of this disease. METHODS Individual patient data were obtained from 19 case series published over the last 23 years through direct communication with the authors. Ordinal logistic regression models were used to [...]

Menée auprès de 2 738 participants soignés dans sept centres internationaux entre 1990 et 2000, cette étude rétrospective longitudinale analyse l'évolution de la survie des patients atteints d'un carcinome épidermoïde de la cavité buccale, en fonction des types de traitements reçus

Improvement in survival of patients with oral cavity squamous cell carcinoma

Amit, Moran ; Yen, Tzu-Chen ; Liao, Chun-Ta ; Chaturvedi, Pankaj ; Agarwal, Jai Prakash ; Kowalski, Luiz P. ; Ebrahimi, Ardalan ; Clark, Jonathan R. ; Kreppel, Matthias ; Zöller, Joachim ; Fridman, Eran ; Bolzoni, Villaret A. ; Shah, Jatin P. ; Binenbaum, Yoav ; Patel, Snehal G. ; Gil, Ziv ; The International Consortium for Outcome Research in, Head ; Neck, Cancer

BACKGROUND An association between the survival of patients with oral cavity squamous cell carcinoma (OCSCC) and advancements in diagnosis and therapy has not been established. METHODS This was a retrospective, longitudinal, international, population-based study of 2738 patients who underwent resection of OCSCC during 2 different decades. Characteristics of patients from 7 international cancer centers who received treatment between 1990 and 2000 (group A; n=735) were compared with patients who [...]

Menée en Corée par enquête auprès de 378 survivants d'un cancer de l'estomac de stade I à III, cette étude analyse la prévalence des idées suicidaires ainsi que les facteurs de risque associés

Suicide ideation in stomach cancer survivors and possible risk factors

Choi, Ye-Ni ; Kim, Young-Ae ; Yun, YoungHo ; Kim, Sung ; Bae, Jae-Moon ; Kim, Young-Woo ; Ryu, KeunWon ; Lee, Junho ; Noh, Jae-Hyung ; Sohn, Tae-Sung

Purpose : Although the suicide rate of cancer survivors is higher than that of the general population, few studies have examined the potential risk factors. We assessed suicide ideation (SI) and investigated its correlates among survivors of stomach cancer, which is one of the most prevalent cancers in Korea. Methods : We surveyed 378 stage I–III stomach cancer survivors who had been disease free for at least 1 year. The survey contained demographic questions and quality of life assessments [...]

Menée à partir des données de 5 044 patients atteints d'un cancer colorectal ou pulmonaire, cette étude américaine analyse leurs sujets d'inquiétude au moment de la prise de décision thérapeutique et en fonction de leur appartenance ethnique

What do cancer patients worry about when making decisions about treatment? Variation across racial/ethnic groups

Martin, MichelleY ; Fouad, MonaN ; Oster, RobertA ; Schrag, Deborah ; Urmie, Julie ; Sanders, Sara ; Pisu, Maria

The aim of this study was to determine the issues patients worry about when making decisions about cancer treatment. A total of 5,044 colorectal and lung cancer patients from the Cancer Care Outcomes Research and Surveillance Consortium reported their level of worry about (1) treatment side effects, (2) treatment costs, (3) time away from family, (4) time away from work, and (5) transportation to treatment sites. Using multivariable logistic regression, we evaluated the association of [...]

A partir d'une revue de la littérature (211 études), cette méta-analyse fait le point sur la prévalence de la dépression, telle qu'elle est évaluée au moment de la consultation d'annonce du diagnostic ou par des instruments d'auto-déclaration, chez les patients atteints de cancer en fonction de la localisation et de la phase du traitement

Prevalence of depression in cancer patients: a meta-analysis of diagnostic interviews and self-report instruments

Krebber, A. M. H. ; Buffart, L. M. ; Kleijn, G. ; Riepma, I. C. ; de Bree, R. ; Leemans, C. R. ; Becker, A. ; Brug, J. ; van Straten, A. ; Cuijpers, P. ; Verdonck-de Leeuw, I. M.

Objective : We aimed to investigate the prevalence of depression in cancer patients assessed by diagnostic interviews and self-report instruments, and to study differences in prevalence between type of instrument, type of cancer and treatment phase. Methods : A literature search was conducted in four databases to select studies on the prevalence of depression among adult cancer patients during or after treatment. A total of 211 studies met the inclusion criteria. Pooled mean prevalence of [...]

Menée auprès de 53 patients atteints de myélome multiple, cette étude analyse la prévalence de déficiences cognitives et neuropsychologiques sévères, un et trois mois après une greffe autologue de cellules souches hématopoïétiques

Acute cognitive impairment in patients with multiple myeloma undergoing autologous hematopoietic stem cell transplant

Jones, Desiree ; Vichaya, Elisabeth G. ; Wang, Xin Shelley ; Sailors, Mary H. ; Cleeland, Charles S. ; Wefel, Jeffrey S.

BACKGROUND Few studies have examined the acute effects of autologous hematopoietic stem cell transplantation (Au-HSCT) on the neuropsychological functioning of patients with multiple myeloma (MM). The prevalence of cognitive deficits after induction chemotherapy (pre-AuHSCT) was examined in patients with MM, clinically significant changes in cognitive function 1 and 3 months post-AuHSCT were determined, and patients who may be vulnerable to cognitive decline during this period were identified. [...]

Menée auprès d'une cohorte de 5 193 anciens combattants américains, cette étude analyse la pertinence de quatre indicateurs psychosociaux (freins, bénéfices, sentiment d'auto-efficacité, optimisme) pour analyser la participation au dépistage du cancer colorectal

Factorial validity and invariance of four psychosocial constructs of colorectal cancer screening: does screening experience matter?

Murphy, Caitlin C. ; McQueen, Amy ; Bartholomew, L. Kay ; Del Junco, Deborah J. ; Coan, Sharon P. ; Vernon, Sally W.

Background: Few studies have examined the psychometric properties and invariance of scales measuring constructs relevant to colorectal cancer screening (CRCS). We sought to: 1) evaluate the factorial validity of four core constructs associated with CRCS (benefits, barriers, self-efficacy, and optimism); and 2) examine measurement invariance by screening status (currently screened, overdue, never screened). Methods: We used baseline survey data from a longitudinal behavioral intervention trial [...]

Menée en Suède auprès de 168 patientes atteintes d'un cancer du sein, cette étude randomisée contrôlée analyse le rapport coût-efficacité d'une intervention psychosociale individuelle au cours du traitement adjuvant (durée de suivi : 2 ans)

Cost–utility analysis of individual psychosocial support interventions for breast cancer patients in a randomized controlled study

Arving, Cecilia ; Brandberg, Yvonne ; Feldman, Inna ; Johansson, Birgitta ; Glimelius, Bengt

Objectives : The aim was to explore the cost–utility in providing complementary individual psychosocial support to breast cancer patients compared with standard care (SC). Methods Patients just starting adjuvant therapy (n=168) at Uppsala University Hospital, Sweden, were consecutively included and randomized into three groups: psychosocial support from a specially trained nurse (INS), from a psychologist (IPS), or SC. Psychological effects and healthcare utilization were monitored during a [...]

Cette étude américaine analyse et compare le rapport coût-efficacité de la protonthérapie et d'une radiothérapie par photons pour traiter les patients pédiatriques atteints de médulloblastome

Cost effectiveness of proton therapy compared with photon therapy in the management of pediatric medulloblastoma

Mailhot Vega, Raymond B. ; Kim, Jane ; Bussière, Marc ; Hattangadi, Jona ; Hollander, Abby ; Michalski, Jeff ; Tarbell, Nancy J. ; Yock, Torunn ; MacDonald, Shannon M.

BACKGROUND Proton therapy has been a hotly contested issue in both scientific publications and lay media. Proponents cite the modality's ability to spare healthy tissue, but critics claim the benefit gained from its use does not validate its cost compared with photon therapy. The objective of this study was to evaluate the cost effectiveness of proton therapy versus photon therapy in the management of pediatric medulloblastoma. METHODS A cost-effective analysis was performed from the societal [...]

Menée auprès de 27 patients atteints d'un cancer de la prostate (âge : de 54 à 82 ans), cette étude qualitative américaine analyse leurs perceptions relatives à une information personnalisée sur les risques associés aux décisions thérapeutiques

The value of personalised risk information: a qualitative study of the perceptions of patients with prostate cancer

Han, Paul K J ; Hootsmans, Norbert ; Neilson, Michael ; Roy, Bethany ; Kungel, Terence ; Gutheil, Caitlin ; Diefenbach, Michael ; Hansen, Moritz

Objective :To explore the experiences of patients with prostate cancer with risk information and their perceptions of the value of personalised risk information in treatment decisions. Design : A qualitative study was conducted using focus groups. Semistructured interviews explored participants’ experiences with using risk information, and their perceptions of the potential value of personalised risk information produced by clinical prediction models. Participants : English-speaking patients, [...]

Cette étude américaine présente et analyse l'efficacité d'un outil vidéo utilisant les témoignages de survivantes afro-américaines d'un cancer du sein pour réduire les disparités ethniques dans la qualité de vie des patientes et communiquer sur l'adhésion aux soins de suivi

A novel intervention using interactive technology and personal narratives to reduce cancer disparities: African American breast cancer survivor stories

Pérez, Maria ; Sefko, JulianneA ; Ksiazek, Deb ; Golla, Balaji ; Casey, Chris ; Margenthaler, JulieA ; Colditz, Graham ; Kreuter, MatthewW ; Jeffe, DonnaB

Purpose : There has been a paucity of interventions developed for African American women to address persistent health disparities between African American and Caucasian breast cancer patients. We developed and piloted a technologically innovative, culturally targeted, cancer-communication intervention for African American breast cancer patients using African American breast cancer survivor stories. Methods : We rated 917 clips from a video library of survivors’ stories for likability, clarity [...]

Menée par entretiens auprès de 54 médecins néerlandais, cette étude analyse leurs pratiques de collaboration avec les spécialistes de soins palliatifs pour prescrire une sédation palliative

Consultation with specialist palliative care services in palliative sedation: considerations of Dutch physicians

Koper, Ian ; Heide, Agnes ; Janssens, Rien ; Swart, Siebe ; Perez, Roberto ; Rietjens, Judith

Purpose : Palliative sedation is considered a normal medical practice by the Royal Dutch Medical Association. Therefore, consultation of an expert is not considered mandatory. The European Association of Palliative Care (EAPC) framework for palliative sedation, however, is more stringent: it considers the use of palliative sedation without consulting an expert as injudicious and insists on input from a multi-professional palliative care team. This study investigates the considerations of Dutch [...]

A partir des données des 22 registres européens du projet RARECARE, cette étude décrit la méthodologie pour estimer la prévalence des cas de cancers rares en Europe

Methodological aspects of estimating rare cancer prevalence in Europe: The experience of the RARECARE project

Mallone, Sandra ; De Angelis, Roberta ; Van der Zwan, Jan Maarten ; Trama, Annalisa ; Siesling, Sabine ; Gatta, Gemma ; Capocaccia, Riccardo

Abstract : This paper describes the usage and the performance evaluation of the completeness index method in the ‘Surveillance of Rare Cancers in Europe project’ (RARECARE) for estimating rare cancer prevalence in Europe. The 15-year prevalence at 1st January 2003 for 255 cancers is obtained from a pool of 22 RARECARE cancer registries (CRs). Incidence and survival models are applied to the RARECARE database to estimate the parameters from which the completeness indices are calculated. Complete [...]

A partir des données du réseau FRANCIM, cette étude française présente un modèle d'estimation de la probabilité brute de la mortalité liée au cancer chez des patients atteints de cinq types de cancer en prenant en compte les autres causes possibles de mortalité

Probabilities of dying from cancer and other causes in French cancer patients based on an unbiased estimator of net survival: A study of five common cancers

Charvat, H. ; Bossard, N. ; Daubisse, L. ; Binder, F. ; Belot, A. ; Remontet, L.

Background : Net survival is the survival that would be observed if cancer were the only possible cause of death. Although it is an important epidemiological tool allowing temporal or geographical comparisons, it cannot inform on the “crude” probability of death of cancer patients; i.e., when taking into account other possible causes of deaths. Methods : In this work, we provide estimates of the crude probabilities of death from cancer and from other causes as well as the probability of being [...]

Cette étude présente les caractéristiques et les objectifs d'un réseau américain constitué d'établissements spécialisés en épidémiologie du cancer

Collaborative Cancer Epidemiology in the 21st Century: the Model of Cancer Consortia

Burgio, Michael R. ; Ioannidis, John P.A. ; Kaminski, Brett M. ; DeRycke, Eric ; Rogers, Scott ; Khoury, Muin J. ; Seminara, Daniela

During the last two decades, epidemiology has undergone a rapid evolution toward collaborative research. The proliferation of multi-institutional, interdisciplinary consortia has acquired particular prominence in cancer research. Herein, we describe the characteristics of a network of 49 established cancer epidemiology consortia (CEC) currently supported by the Epidemiology and Genomics Research Program (EGRP) at the National Cancer Institute (NCI). This collection represents the largest [...]