A partir des données des registres américains des cancers, cette étude analyse la prévalence d'une incontinence urinaire en population générale âgée et l'impact de celle-ci sur la qualité de vie des survivants d'un cancer

Urinary incontinence and health-related quality of life among older Americans with and without cancer: a cross-sectional study

White, Alexandra ; Reeve, Bryce ; Chen, Ronald ; Stover, Angela ; Irwin, Debra

BACKGROUND:Few studies have investigated the impact of urinary incontinence (UI) on health-related quality of life (HRQOL) among cancer survivors. UI is prevalent in the general population and can be both an indicator of cancer and a side effect of cancer treatment. UI and cancer diagnoses have been associated with decreases in HRQOL. This study evaluates the prevalence of UI and the impact on HRQOL among older cancer survivors. METHODS:The prevalence of UI among cancer survivors (breast, [...]

Menée par entretiens, cette étude observationnelle multicentrique analyse les attitudes des patients atteints de cancer vis-à-vis de leurs troubles du sommeil pendant la chimiothérapie

Patients attitudes towards sleep disturbances during chemotherapy

Romito, F. ; Cormio, C. ; De Padova, S. ; Lorusso, V. ; Berio, M. A. ; Fimiani, F. ; Piattelli, A. ; Palazzo, S. ; Abram, G. ; Dudine, L. ; Guglielmi, A. ; Galise, I. ; Romito, S. ; Mattioli, V.

Sleep disturbances are among the most distressing symptoms in cancer: they often co-occur with fatigue, pain and psychological distress. Despite the negative impact on quality of life, patients rarely seek help for managing their sleep disturbances. This paper presents the results of a multicentre observational study on patients' attitudes towards their sleep problems. The study also investigates symptom correlates. Patients responded to a semi-structured interview and completed the following [...]

Mené auprès de 410 survivants d'un cancer, cet essai multicentrique évalue l'efficacité d'un programme de yoga pour améliorer la qualité de leur sommeil après le traitement

Multicenter, Randomized Controlled Trial of Yoga for Sleep Quality Among Cancer Survivors

Mustian, Karen M. ; Sprod, Lisa K. ; Janelsins, Michelle ; Peppone, Luke J. ; Palesh, Oxana G. ; Chandwani, Kavita ; Reddy, Pavan S. ; Melnik, Marianne K. ; Heckler, Charles ; Morrow, Gary R.

Purpose : Thirty percent to 90% of cancer survivors report impaired sleep quality post-treatment, which can be severe enough to increase morbidity and mortality. Lifestyle interventions, such as exercise, are recommended in conjunction with drugs and cognitive behavioral therapy for the treatment of impaired sleep. Preliminary evidence indicates that yoga—a mind-body practice and form of exercise—may improve sleep among cancer survivors. The primary aim of this randomized, controlled clinical [...]

Menée auprès de 8 690 survivants d'un cancer, cette étude américaine analyse l'impact d'un programme en ligne sur leurs comportements de santé

Impact of internet-based cancer survivorship care plans on health care and lifestyle behaviors

Hill-Kayser, Christine E. ; Vachani, Carolyn C. ; Hampshire, Margaret K. ; Di Lullo, Gloria ; Jacobs, Linda A. ; Metz, James M.

BACKGROUND : Survivorship care plans (SCP) are currently recommended by the Institute of Medicine, and will soon be required for accreditation by the American College of Surgeons Commission on Cancer. To the best of the authors' knowledge, the impact of SCPs on cancer survivors has not been previously reported. METHODS : In 2007, the authors created an Internet tool for the creation of SCPs that provides customized guidelines for survivorship care. Users are sent a voluntary follow-up survey 1 [...]

Mené auprès de 42 survivantes d'un cancer du sein, cet essai évalue l'efficacité d'un programme de physiothérapie avec des exercices d'aquagym pour soulager leur fatigue liée au cancer et améliorer leur qualité de vie

A multimodal physiotherapy programme plus deep water running for improving cancer-related fatigue and quality of life in breast cancer survivors

Cuesta-Vargas, A. I. ; Buchan, J. ; Arroyo-Morales, M.

The aim of the study was to assess the feasibility and effectiveness of aquatic-based exercise in the form of deep water running (DWR) as part of a multimodal physiotherapy programme (MMPP) for breast cancer survivors. A controlled clinical trial was conducted in 42 primary breast cancer survivors recruited from community-based Primary Care Centres. Patients in the experimental group received a MMPP incorporating DWR, 3 times a week, for an 8-week period. The control group received a leaflet [...]

Menée en Nouvelle-Zélande et en Australie auprès de patients atteints d'un cancer de la prostate traité ou non à l'aide d'une hormonothérapie anti-androgénique, cette étude analyse leurs perceptions relatives à l'importance d'une activité physique pour maintenir leur qualité de vie

Perceptions of physically active men with prostate cancer on the role of physical activity in maintaining their quality of life: possible influence of androgen deprivation therapy

Keogh, Justin W. L. ; Patel, Asmita ; MacLeod, Roderick D. ; Masters, Jonathan

Objective : The primary aim of this study was to examine the perceptions of older men with prostate cancer regarding their quality of life and physical activity post-diagnosis, and the potential benefits and risks associated with being physically active. A secondary aim was to gain some preliminary insight into how these perceptions may differ as a function of androgen deprivation therapy (ADT). Methods : Two focus groups were conducted, consisting of six ADT and eight non-ADT men, [...]

A partir de données de 459 participantes traitées dans un centre de lutte contre le cancer à Chicago, cette étude analyse les facteurs cliniques et génétiques associés à une prise de poids chez des patientes atteintes d'un cancer du sein

Clinical and genetic predictors of weight gain in patients diagnosed with breast cancer

Reddy, S. M. ; Sadim, M. ; Li, J. ; Yi, N. ; Agarwal, S. ; Mantzoros, C. S. ; Kaklamani, V. G.

Background: Post-diagnosis weight gain in breast cancer patients has been associated with increased cancer recurrence and mortality. Our study was designed to identify risk factors for this weight gain and create a predictive model to identify a high-risk population for targeted interventions. Methods: Chart review was conducted on 459 breast cancer patients from Northwestern Robert H. Lurie Cancer Centre to obtain weights and body mass indices (BMIs) over an 18-month period from diagnosis. We [...]

Menée auprès de 200 patientes coréennes atteintes d'un cancer du sein et recevant une chimiothérapie, cette étude transversale analyse l'association entre des symptômes de la ménopause, les fonctions sexuelles, la dépression et leur qualité de vie

Menopausal symptoms, sexual function, depression, and quality of life in Korean patients with breast cancer receiving chemotherapy

Park, Hyojung ; Yoon, HyeonGyeong

Purpose : The purpose of this study was to study the relationships among menopausal symptoms, sexual function, depression, and quality of life in women with breast cancer undergoing chemotherapy. Methods : Two hundred women participated in this cross-sectional study. Data were collected with the Menopause Rating Scale (MRS), Female Sexual Function Index (FSFI), Beck Depression Inventory II (BDI-II), and the Functional Assessment of Cancer Therapy—Breast Cancer (FACT-B). Data were analyzed using [...]

Menée auprès de 535 participantes, cette étude prospective américaine analyse la qualité de vie de survivantes à long terme d'un cancer du sein (en moyenne 12, 5 années après le diagnostic)

Quality of Life in Long-Term Breast Cancer Survivors

Hsu, Tina ; Ennis, Marguerite ; Hood, Nicky ; Graham, Margaret ; Goodwin, Pamela J.

Purpose : There is considerable interest in the quality of life (QOL) of long-term breast cancer (BC) survivors. We studied changes in QOL from time of BC diagnosis to long-term survivorship and compared QOL in long-term survivors to that of age-matched women with no history of BC. Patients and Methods : In all, 535 women with localized BC (T1-3N0-1M0) were recruited from 1989 to 1996 and followed prospectively, completing QOL questionnaires at diagnosis and 1 year postdiagnosis. Between 2005 [...]

Menée en Espagne, cette étude analyse les disparités géographiques dans l'évolution de la mortalité par cancer de l'estomac sur la période 1975-2008

Spatio-temporal trends in gastric cancer mortality in Spain: 1975–2008

Aragonés, Nuria ; Goicoa, Tomás ; Pollan, Marina ; Militino, Ana F. ; Pérez-Gómez, Beatriz ; López-Abente, Gonzalo ; Ugarte, M. Dolores

Aim of the study: There has been a downward trend in gastric cancer mortality worldwide. In Spain, a marked spatial aggregation of areas with excess mortality due to this cause has long been reported. This paper sought to analyse the evolution of gastric cancer mortality risk in Spanish provinces and explore the possible attenuation of the geographical pattern. Methods: We studied a series of gastric cancer mortality data by province, year of death, sex and age group using a conditional [...]

Menée auprès de 1 642 survivants d'un cancer résidant en zone rurale et de 6 162 survivants d'un cancer résidant en zone urbaine, cette étude américaine analyse les disparités en termes de comportements de santé chez ces deux groupes (prévalence du tabagisme, activité physique, obésité/surpoids, consommatinon d'alcool)

Rural–urban differences in health behaviors and implications for health status among US cancer survivors

Weaver, KathrynE ; Palmer, Nynikka ; Lu, Lingyi ; Case, L. Douglas ; Geiger, AnnM

Purpose : Rural US adults have increased risk of poor outcomes after cancer, including increased cancer mortality. Rural–urban differences in health behaviors have been identified in the general population and may contribute to cancer health disparities, but have not yet been examined among US survivors. We examined rural–urban differences in health behaviors among cancer survivors and associations with self-reported health and health-related unemployment. Methods : We identified rural (n = [...]

Cette étude présente une estimation de l'incidence, de la prévalence et de la mortalité par cancer en Corée, sur la période 2000-2020

Burden of cancer in Korea during 2000–2020

Park, Jae-Hyun ; Lee, Kwang-Sig ; Choi, Kyu-Sik

Background: This study estimates the burden of cancer in Korea during 2000–2020, ameliorating the Global Burden of Disease Study Group (GBD) method with the Incidence–Prevalence–Mortality (IPM) Model. Methods: Besides using the GBD approach to calculate the Years of Life Lost in Korea during 2000–2020, this research calculates the Years Lived with Disability (YLDs) of major cancers based on the combination of the GBD method and the IPM Model. Results: Colon, breast and thyroid cancers became [...]

A partir des données du registre finlandais des cancers incluant 13 860 participants, cette étude analyse la morbidité cardiovasculaire chez des survivants à long terme d'un cancer diagnostiqué au début de l'âge adulte

Cardiovascular morbidity in long-term survivors of early-onset cancer: A population-based study

Kero, A. E. ; Järvelä, L. S. ; Arola, M. ; Malila, N. ; Madanat-Harjuoja, L. M. ; Matomäki, J. ; Lähteenmäki, P. M.

Improvements in cancer therapy have resulted in an expanding population of early-onset cancer survivors. In contrast to childhood and adolescent cancer survivors, there is still a lack of data concerning late morbidities among young adult (YA) cancer survivors. Thus, our aim was to investigate cardiac and vascular morbidity among early-onset cancer survivors with a special interest in YA cancer survivors. In a population-based setting, we explored the risk of cardiovascular disease in [...]

A partir des données de l'OMS portant sur 34 pays européens, cette étude présente la mortalité par 25 types de cancer en Europe, sur la période 2005-2009, et analyse son évolution depuis les années 1980

Cancer mortality in Europe, 2005–2009, and an overview of trends since 1980

Bosetti, C. ; Bertuccio, P. ; Malvezzi, M. ; Levi, F. ; Chatenoud, L. ; Negri, E. ; La Vecchia, C.

Background After a peak in the late 1980s, cancer mortality in Europe has declined by 10% in both sexes up to the early 2000s. We provide an up-to-date picture of patterns and trends in mortality from major cancers in Europe. Methods We analyzed cancer mortality data from the World Health Organization for 25 cancer sites and 34 European countries (plus the European Union, EU) in 2005–2009. We computed age-standardized rates (per 100 000 person-years) using the world standard population and [...]

Cette étude analyse et compare, pour la Nouvelle-Zélande et pour l'Australie, l'évolution de la mortalité par mélanome sur la période 1968 à 2007

A comparison of trends in melanoma mortality in New Zealand and Australia: the two countries with the highest melanoma incidence and mortality in the world

Sneyd, Mary Jane ; Cox, Brian

BACKGROUND:New Zealand and Australia have the highest incidence and mortality rates from cutaneous melanoma in the world. The predominantly fair-skinned New Zealanders and Australians both enjoy sun, tanned skin and the outdoors, and differences in these activities among generations have been important determinants of trends in melanoma mortality.We examined whether New Zealand trends in melanoma mortality mirror those in Australia, through detailed comparison of the trends in both countries [...]

A partir des données des registres américains des cancers portant sur 29 527 participants, cette étude évalue et compare, dans des zones urales et urbaines, l'incidence et le pronostic des cancers de l'œsophage et du cardia sur la période 2004-2009

Incidence and prognosis of gastroesophageal cancer in rural, urban, and metropolitan areas of the United States

Wang, Zhensheng ; Goodman, Michael ; Saba, Nabil ; El-Rayes, Bassel F.

BACKGROUND The objective of this study was assess differences in the incidence, late-stage diagnosis, and prognosis of squamous cell carcinoma of the esophagus (SCCE), adenocarcinoma of the esophagus (AE), and adenocarcinoma of the gastric cardia (AGC) in metropolitan, urban, and rural areas in the United States. METHODS The authors identified 29,527 patients with SCCE, AE, or AGC who were reported to the Surveillance, Epidemiology, and End Results Program between 2004 and 2009. Incidence [...]

A partir des données du registre californien des cancers incluant 14 280 participants, cette étude rétrospective analyse les les facteurs individuels, cliniques et socioéconomiques impliqués dans les disparités de mortalité par cancer du poumon non à petites cellules parmi les Américains d'origine hispanique

How Do Social Factors Explain Outcomes in Non–Small-Cell Lung Cancer Among Hispanics in California? Explaining the Hispanic Paradox

Patel, Manali I. ; Schupp, Clayton W. ; Gomez, Scarlett L. ; Chang, Ellen T. ; Wakelee, Heather A.

Purpose : Hispanics in the United States have lower age-adjusted mortality resulting from non–small-cell lung cancer (NSCLC) compared with non-Hispanic whites (NHWs). The purpose of this study was to evaluate individual, clinical, and neighborhood factors in survival among Hispanics with NSCLC. Patients and Methods : We performed a retrospective analysis of NHWs and Hispanics with NSCLC between 1998 and 2007 in the California Cancer Registry (follow-up to December 2009). Kaplan-Meier curves [...]

A partir des données des registres américains du cancer portant sur 55 153 patientes âgées de 18 à 39 ans et atteintes d'un cancer du sein diagnostiqué entre 1973 et 2009, cette étude analyse les disparités ethniques dans le diagnostic et la survie

Comparison of clinicopathologic features and survival in young American women aged 18-39 years in different ethnic groups with breast cancer

Liu, P. ; Li, X. ; Mittendorf, E. A. ; Li, J. ; Du, X. L. ; He, J. ; Ren, Y. ; Yang, J. ; Hunt, K. K. ; Yi, M.

Background: Ethnic disparities in breast cancer diagnoses and disease-specific survival (DSS) rates in the United States are well known. However, few studies have assessed differences specifically between Asians American(s) and other ethnic groups, particularly among Asian American(s) subgroups, in women aged 18–39 years. Methods: The Surveillance, Epidemiology, and End Results database was used to identify women aged 18–39 years diagnosed with breast cancer from 1973 to 2009. Incidence rates, [...]

Menée auprès de 3 345 patientes atteintes d'un cancer du sein de stade I à III avant 50 ans, cette étude américaine analyse et compare la survie à 10 ans de patientes présentant ou non une mutation BRCA1

Ten-Year Survival in Patients With BRCA1-Negative and BRCA1-Positive Breast Cancer

Huzarski, Tomasz ; Byrski, Tomasz ; Gronwald, Jacek ; Górski, Bohdan ; Domagała, Pawel ; Cybulski, Cezary ; Oszurek, Oleg ; Szwiec, Marek ; Gugała, Karol ; Stawicka, Malgorzata ; Morawiec, Zbigniew ; Mierzwa, Tomasz ; Janiszewska, Hanna ; Kilar, Ewa ; Marczyk, Elzbieta ; Kozak-Klonowska, Beata ; Siołek, Monika ; Surdyka, Dariusz ; Wiśniowski, Rafal ; Posmyk, Michal ; Sun, Ping ; Lubinski, Jan ; Narod, Steven A.

Purpose : To estimate 10-year overall survival (OS) rates for patients with early-onset breast cancer, with and without a BRCA1 mutation, and to identify prognostic factors among those with BRCA1-positive breast cancer. Patients and Methods : A total of 3,345 women with stage I to III breast cancer, age ≤ 50 years, were tested for three founder mutations in BRCA1. Information on tumor characteristics and treatments received was retrieved from medical records. Dates of death were obtained from [...]

A partir des données des registres américains des cancers, cette étude analyse, sur la période 1985-2009, les disparités ethniques dans l'évolution de la survie des patientes atteintes d'un cancer du col de l'utérus

Racial disparities in cervical cancer survival over time

Rauh-Hain, J. Alejandro ; Clemmer, Joel T. ; Bradford, Leslie S. ; Clark, Rachel M. ; Growdon, Whitfield B. ; Goodman, Annekathryn ; Boruta, David M. ; Schorge, John O. ; del Carmen, Marcela G.

BACKGROUND The purpose of this study is to examine changes over time in survival for African American (AA) and white women diagnosed with cervical cancer (CC). METHODS Surveillance, Epidemiology, and End Results (SEER) Program data from 1985 to 2009 were used for this analysis. Racial differences in survival were evaluated between African American (AA) and white women. Kaplan-Meier and Cox proportional hazards survival methods were used to assess differences in survival by race at 5-year [...]

A partir d'échantillons tumoraux prélévés sur 175 femmes atteintes d'un cancer du col de l'utérus, cette étude analyse la prévalence ainsi que la distribution, par sous-type histologique, du papillomavirus humain

Human papillomavirus genotypes distribution in 175 invasive cervical cancer cases from Brazil

de Oliveira, Cristina ; Fregnani, Jose Humberto Tavares Guerreiro ; Carvalho, Jesus ; Longatto-Filho, Adhemar ; Levi, Jose

BACKGROUND:Invasive cervical cancer is the second most common malignant tumor affecting Brazilian women. Knowledge on Human Papillomavirus (HPV) genotypes in invasive cervical cancer cases is crucial to guide the introduction and further evaluate the impact of new preventive strategies based on HPV. We aimed to provide updated comprehensive data about the HPV types' distribution in patients with invasive cervical cancer. METHODS:Fresh tumor tissue samples of histologically confirmed invasive [...]

A partir des données du registre néerlandais des cancers, cette étude analyse l'évolution de l'incidence du cancer du larynx, des traitements associés et de la mortalité sur la période 1989-2010

Progress against laryngeal cancer in The Netherlands between 1989 and 2010

van Dijk, Boukje A. C. ; Karim-Kos, Henrike E. ; Coebergh, Jan Willem ; Marres, Henri A. M. ; de Vries, Esther

Cancer of the larynx is a frequently occurring head and neck cancer in The Netherlands. The main risk factors are smoking and excessive alcohol consumption. The aim of our study was to evaluate the progress against laryngeal cancer by studying trends in incidence, mortality and survival in The Netherlands. All patients in The Netherlands Cancer Registry diagnosed with invasive primary squamous cell carcinoma of the larynx during the period 1989–2010 were included for analysis. Time trends in [...]

Menée au Royaume-Uni à partir d'échantillons tumoraux de carcinome du rhinopharynx prélevés sur 67 patients, cette étude observationnelle évalue la prévalence d'une infection par le papillomavirus humain, en fonction de son sous-type histologique, ainsi que son effet sur la survie

Oncogenic human papillomavirus-associated nasopharyngeal carcinoma: an observational study of correlation with ethnicity, histological subtype and outcome in a UK population

Robinson, Max ; Suh, Yae-eun ; Paleri, Vinidh ; Devlin, Debbie ; Ayaz, Bushra ; Pertl, Laura ; Thavaraj, Selvam

BACKGROUND:Nasopharyngeal carcinoma (NPC) accounts for 0.6% of all cancers worldwide with the highest prevalence in South East Asia, Southern China and Northern Africa but the disease is uncommon in Europe with an annual incidence in this region of less than 1 per 100 000. Although the Epstein-Barr virus (EBV) is a well known causative agent in NPC, recent reports have implicated oncogenic Human Papillomavirus (HPV) in a subgroup of these tumours. The recent striking rise of oropharyngeal [...]

Menée à Taïwan auprès de 15 894 patients atteints d'un cancer de la tête et du cou et portant sur 772 cas et sur 15 122 témoins, cette étude analyse le risque de pneumonie liée à une radiothérapie et identifie les facteurs associés

Incidence of pneumonia and risk factors among patients with head and neck cancer undergoing radiotherapy

Chu, Chin-Nan ; Muo, Chih-Hsin ; Chen, Shang-Wen ; Lyu, Shu-Yu ; Morisky, Donald

BACKGROUND:This study investigated the incidence and patient- and treatment-related risk factors related to pneumonia acquired during radiotherapy (PNRT) in head and neck cancer (HNC) patients. METHODS:Using the universal insurance claims data, 15,894 total HNC patients between 1998 and 2007 were included in this analysis. PNRT was defined as the occurrence of pneumonia within 90 days of the commencement of radiotherapy. Information also included some demographic characteristics, [...]

A partir d'une revue systématique de la littérature (17 études, 3 497 cas), cette méta-analyse évalue la prévalence des symptômes de dépression et d'anxiété chez des patients chinois adultes atteints de cancer

The prevalence of depression and anxiety among Chinese adults with cancer: a systematic review and meta-analysis

Yang, Yi-Long ; Liu, Li ; Wang, Yang ; Wu, Hui ; Yang, Xiao-Shi ; Wang, Jia-Na ; Wang, Lie

BACKGROUND:A lot of empirical studies have been conducted to evaluate the prevalence of depression and anxiety among Chinese adults with cancer. We aimed to conduct a meta-analysis in order to evaluate the prevalence and odds ratios of depression and anxiety in Chinese adults with cancer compared with those without. METHODS:The three most comprehensive computerized Chinese academic databases-CNKI, Wangfang and Vip databases-were systematically screened through September 2012. PubMed and Web of [...]

Menée auprès de 335 jeunes survivants d'un cancer (âge moyen : 31,8 ans), cette étude de cohorte américaine analyse la prévalence d'une détresse psychologique et identifie les facteurs associés

Distress among young adult cancer survivors: a cohort study

Yanez, Betina ; Garcia, SofiaF ; Victorson, David ; Salsman, JohnM

Purpose : Being diagnosed with cancer as a young adult can lead to significant psychological distress and impaired quality of life. Compared to children and older adults diagnosed with cancer, fewer studies have addressed psychological distress among young adult cancer survivors. This study sought to identify the prevalence of, and factors associated with, distress among young adult cancer survivors (ages 18–39). Methods : Young adult cancer survivors (N = 335, mean age = 31.8, women = 68.4 %) [...]

A partir des données du registre néerlandais des cancers portant sur 3 080 participants, cette étude prospective évalue l'association entre des symptômes dépressifs et la mortalité toutes causes confondues

Depressive symptoms are a risk factor for all-cause mortality: results from a prospective population-based study among 3,080 cancer survivors from the PROFILES registry

Mols, Floortje ; Husson, Olga ; Roukema, Jan-Anne ; Poll-Franse, LonnekeV

Background : The goal of this large prospective population-based study was to examine the association between depressive symptoms and all-cause mortality among cancer survivors up to 10 years post-diagnosis. Methods : All currently alive individuals diagnosed with endometrial or colorectal cancer (CRC) between 1998 and 2007 or with lymphoma or multiple myeloma between 1999 and 2008, as registered in the Eindhoven Cancer Registry, received a questionnaire on depressive symptoms (Hospital Anxiety [...]

Menée au Danemark auprès de 7 085 cas et de 13 105 témoins, cette étude de cohorte en population analyse le risque à long terme de troubles psychiques chez des survivants d'un cancer pédiatrique, ainsi que chez leurs frères et sœurs

Hospital contact for mental disorders in survivors of childhood cancer and their siblings in Denmark: a population-based cohort study

Lund, Lasse Wegener ; Winther, Jeanette F. ; Dalton, Susanne O. ; Cederkvist, Luise ; Jeppesen, Pia ; Deltour, Isabelle ; Hargreave, Marie ; Kjær, Susanne K. ; Jensen, Allan ; Rechnitzer, Catherine ; Andersen, Klaus K. ; Schmiegelow, Kjeld ; Johansen, Christoffer

Background Survivors of childhood cancer are known to be at risk for long-term physical and mental effects. However, little is known about how cancers can affect mental health in the siblings of these patients. We aimed to assess the long-term risks of mental disorders in survivors of childhood cancer and their siblings. Methods : Hospital contact for mental disorders was assessed in a population-based cohort of 7085 Danish children treated for cancer by contemporary protocols between 1975 and [...]

Menée auprès de 76 cas et de 76 témoins, cette étude américaine analyse les facteurs démographiques, psychosociaux et cliniques associés aux symptômes de dépression chez des femmes afro-américaines atteintes d'un cancer du sein

Correlates of depressive symptomatology in African-American breast cancer patients

Sheppard, VanessaB ; Llanos, AdanaA ; Hurtado-de-Mendoza, Alejandra ; Taylor, TeletiaR ; Adams-Campbell, LucileL

Purpose : This study assessed the levels of depressive symptomatology in African-American women with breast cancer compared to those of women without breast cancer and examined demographic, psychosocial, and clinical factors correlated with depression. Methods : A total of 152 African-American women were recruited from Washington, DC and surrounding suburbs. Breast cancer patients (n=76 cases) were recruited from a health care center and women without cancer were recruited from health fairs [...]

Menée auprès de 192 patientes atteintes d'un cancer du sein, cette étude américaine analyse les effets des croyances religieuses sur leurs comportements et attitudes face à la maladie et sur leur qualité de vie

It is out of my hands: how deferring control to God can decrease quality of life for breast cancer patients

McLaughlin, Bryan ; Yoo, Woohyun ; D'Angelo, Jonathan ; Tsang, Stephanie ; Shaw, Bret ; Shah, Dhavan ; Baker, Timothy ; Gustafson, David

Objective : This paper seeks to contribute to the understanding of how and why religion affects psychosocial health outcomes. We propose a theoretical model predicting that when women with breast cancer defer control to God they will experience fewer breast cancer related concerns. Deferring control to God, however, should also reduce the likelihood that they take a proactive coping approach, which will be exacerbated by lowered breast cancer concerns. We therefore predict that this passive [...]

Menée auprès de 284 participantes, cette étude coréenne analyse la prévalence et les facteurs associés à des idées suicidaires chez des patientes atteintes d'un cancer du sein, une semaine et un an après traitement chirurgical

Determinants of suicidal ideation in patients with breast cancer

Kim, Jae-Min ; Jang, Ji-Eun ; Stewart, Robert ; Kim, Seon-Young ; Kim, Sung-Wan ; Kang, Hee-Ju ; Shin, Il-Seon ; Park, Min-Ho ; Yoon, Jung-Han ; Yoon, Jin-Sang

Background : Breast cancer survivors are at higher risk of psychological problems including suicidal ideation. However, studies on suicidal ideation in breast cancer survivors have been rare and have not been investigated prospectively. This study aimed to investigate the prevalence and independent risk factors for suicidal ideation within 1 week and at 1 year after breast surgery for breast cancer. Methods : A total of 284 patients with breast cancer were evaluated within 1 week after breast [...]

Menée auprès de 126 patients âgés de 3 à 21 ans lors d'un diagnostic de médulloblastome, cette étude prospective longitudinale analyse leurs capacités cognitives (vitesse de traitement de l'information, concentration, mémoire de travail) sur une période de cinq années après le traitement

Processing Speed, Attention, and Working Memory After Treatment for Medulloblastoma: An International, Prospective, and Longitudinal Study

Palmer, Shawna L. ; Armstrong, Carol ; Onar-Thomas, Arzu ; Wu, Shengjie ; Wallace, Dana ; Bonner, Melanie J. ; Schreiber, Jane ; Swain, Michelle ; Chapieski, Lynn ; Mabbott, Donald ; Knight, Sarah ; Boyle, Robyn ; Gajjar, Amar

Purpose : The current study prospectively examined processing speed (PS), broad attention (BA), and working memory (WM) ability of patients diagnosed with medulloblastoma over a 5-year period. Patients and Methods : The study included 126 patients, ages 3 to 21 years at diagnosis, enrolled onto a collaborative protocol for medulloblastoma. Patients were treated with postsurgical risk-adapted craniospinal irradiation (n = 36 high risk [HR]; n = 90 average risk) followed by four cycles of [...]

A partir d'une revue de la littérature publiée sur les cinq dernières années, cette étude fait le point sur le rôle de l'infirmière dans le suivi des soins dispensés à des survivants d'un cancer, en insistant sur les besoins spécifiques des survivants d'un cancer de la tête et du cou

Nurse-led follow-up care for cancer patients: what is known and what is needed

Leeuw, Jacqueline ; Larsson, Maria

Traditionally, cancer patient follow-up has focused on disease surveillance and detecting recurrence. However, an increasing number of patients who have survived cancer acknowledge the importance of cancer rehabilitation issues and the need for more patient-oriented models of care by reporting their unmet physical, emotional, and social needs. Nurse-led follow-up care for cancer patients fulfills this need and has been developing gradually for various cancer diagnoses and prognoses. A growing [...]

Menée auprès de 1 556 survivants adultes d'un cancer, cette étude américaine évalue l'impact de leurs difficultés financières sur l'abandon ou le report de soins médicaux

Are survivors who report cancer-related financial problems more likely to forgo or delay medical care?

Kent, Erin E. ; Forsythe, Laura P. ; Yabroff, K. Robin ; Weaver, Kathryn E. ; de Moor, Janet S. ; Rodriguez, Juan L. ; Rowland, Julia H.

BACKGROUND Financial problems caused by cancer and its treatment can substantially affect survivors and their families and create barriers to seeking health care. METHODS The authors identified cancer survivors diagnosed as adults (n = 1556) from the nationally representative 2010 National Health Interview Survey. Using multivariable logistic regression analyses, the authors report sociodemographic, clinical, and treatment-related factors associated with perceived cancer-related financial [...]

Menée en Irlande auprès de 228 participants, cette étude analyse les coûts, en argent et en temps, supportés par les aidants des patients atteints d'un cancer colorectal

How much does it cost to care for survivors of colorectal cancer? Caregiver’s time, travel and out-of-pocket costs

Hanly, Paul ; Céilleachair, AlanÓ ; Skally, Mairead ; O’Leary, Eamonn ; Kapur, Kanika ; Fitzpatrick, Patricia ; Staines, Anthony ; Sharp, Linda

Purpose : Cancer treatment is increasingly delivered in an outpatient setting. This may entail a considerable economic burden for family members and friends who support patients/survivors. We estimated financial and time costs associated with informal care for colorectal cancer. Methods : Two hundred twenty-eight carers of colorectal cancer survivors diagnosed on October 2007–September 2009 were sent a questionnaire. Informal care costs included hospital- and domestic-based foregone caregiver [...]

Menée auprès de 1 597 femmes âgées de 25 à 70 ans à risque familial de cancer, cette étude prospective néerlandaise analyse le rapport coût-efficacité d'un dépistage de cancer du sein par IRM pour des femmes porteuses d'une mutation BRCA1 ou BRCA2

Cost-Effectiveness of Screening Women With Familial Risk for Breast Cancer With Magnetic Resonance Imaging

Saadatmand, Sepideh ; Tilanus-Linthorst, Madeleine M. A. ; Rutgers, Emiel J. T. ; Hoogerbrugge, Nicoline ; Oosterwijk, Jan C. ; Tollenaar, Rob A. E. M. ; Hooning, Maartje ; Loo, Claudette E. ; Obdeijn, Inge-Marie ; Heijnsdijk, Eveline A. M. ; de Koning, Harry J.

Background : To reduce mortality, women with a family history of breast cancer are often screened with mammography before age 50 years. Additional magnetic resonance imaging (MRI) improves sensitivity and is cost-effective for BRCA1/2 mutation carriers. However, for women with a family history without a proven mutation, cost-effectiveness is unclear. Methods : We evaluated data of the largest prospective MRI screening study (MRISC). Between 1999 and 2007, 1597 women (8370 woman-years at risk) [...]

A partir d'une revue systématique de la littérature (22 études), cette étude fait le point sur les coûts des traitements des tumeurs neuroendrocrines ainsi que sur les bénéfices en terme de qualité de vie des patients

Quality of life, resource utilisation and health economics assessment in advanced neuroendocrine tumours: a systematic review

Chau, I. ; Casciano, R. ; Willet, J. ; Wang, X. ; Yao, J. C.

Neuroendocrine tumours (NET) are often diagnosed at an advanced stage when the prognosis is poor for patients, who often experience diminished quality of life (QoL). As new treatments for NET become available, it is important to characterise the associated outcomes, costs and QoL. A comprehensive search was performed to systematically review available data in advanced NET regarding cost of illness/resource utilisation, economic studies/health technology assessment and QoL. Four rounds of [...]

Menée auprès de 51 patientes atteintes d'un cancer du sein et de 53 témoins, cette étude analyse leurs préférences vis-à-vis des informations relatives au pronostic lors de l'entrée en soins palliatifs

Explicit Prognostic Information and Reassurance About Nonabandonment When Entering Palliative Breast Cancer Care: Findings From a Scripted Video-Vignette Study

van Vliet, Liesbeth M. ; van der Wall, Elsken ; Plum, Nicole M. ; Bensing, Jozien M.

Purpose : When discussing the transition to palliative care for patients with breast cancer, oncologists have to find a balance between giving explicit information while not overwhelming patients and being realistic while remaining hopeful. It is unclear whether patients prefer more or less explicit prognostic information, and reassuring patients that they will not be abandoned may provide realistic hope. We assessed the effect of explicit prognostic information and reassurance about [...]

Mené auprès de 88 patientes atteintes d'un cancer du sein, cet essai randomisé évalue l'efficacité d'un programme en ligne destiné à leur permettre de créer leur propre site web afin de rapporter leur expérience de la maladie et de communiquer sur les réseaux sociaux

Project Connect Online: Randomized Trial of an Internet-Based Program to Chronicle the Cancer Experience and Facilitate Communication

Stanton, Annette L. ; Thompson, Elizabeth H. ; Crespi, Catherine M. ; Link, John S. ; Waisman, James R.

Purpose : Evidence suggests that expressing emotions related to cancer and receiving interpersonal support can promote psychological and physical health in women diagnosed with breast cancer. However, adaptive expression of feelings and communication with one’s social network can pose challenges for patients with cancer. We report on a randomized controlled trial of an intervention, Project Connect Online, for patients with breast cancer to create personal Web sites to chronicle their [...]

Menée par entretiens auprès de patientes atteintes d'un cancer du sein et souhaitant bénéficier d'une reconstruction mammaire, cette étude qualitative analyse les disparités dans l'accès aux soins, le choix d'un traitement chirurgical et l'information reçue

Exploring inequalities in access to care and the provision of choice to women seeking breast reconstruction surgery: a qualitative study

Potter, S. ; Mills, N. ; Cawthorn, S. ; Wilson, S. ; Blazeby, J.

Background: Breast reconstruction (BR) may improve psychosocial and cosmetic outcomes after mastectomy for breast cancer but currently, few women opt for surgery. Reasons for this are unclear. The aim of this qualitative study was to explore access to care and the provision of procedure choice to women seeking reconstructive surgery. Methods: Semi-structured interviews with a purposive sample of patients who had undergone BR and professionals providing specialist care explored participants’ [...]

Menée à partir d'une enquête auprès de 394 femmes en bonne santé, cette étude évalue l'impact de différents termes utilisés pour décrire un carcinome canalaire in situ (cancer, lésions, cellules anormales) sur le choix du traitement (chirurgie, médication, surveillance médicale)

Impact of ductal carcinoma in situ terminology on patient treatment preferences

Omer, Z. B. ; Hwang, E. ; Esserman, L. J. ; Howe, R. ; Ozanne, E. M.

Ductal carcinoma in situ (DCIS) is a preinvasive malignancy of the breast and is diagnosed in more than 50 000 women a year in the United States. It is treated with either mastectomy or lumpectomy, often combined with radiation therapy. In cases of low-grade DCIS, studies suggest that if progression occurs, it does so within a time frame of 5 to 40 years and possibly in only 20% of DCIS cases. This raises the possibility that some cases of DCIS will follow an indolent course that will not [...]

Cette étude américaine analyse les biais présents dans les études observationelles visant à évaluer l'influence d'une exposition à un agent cancérogène, après le diagnostic, sur le risque de récidive et la survie

Threats to Validity of Nonrandomized Studies of Postdiagnosis Exposures on Cancer Recurrence and Survival

Chubak, Jessica ; Boudreau, Denise M. ; Wirtz, Heidi S. ; McKnight, Barbara ; Weiss, Noel S.

Studies of the effects of exposures after cancer diagnosis on cancer recurrence and survival can provide important information to the growing group of cancer survivors. Observational studies that address this issue generally fall into one of two categories: 1) those using health plan automated data that contain “continuous” information on exposures, such as studies that use pharmacy records; and 2) survey or interview studies that collect information directly from patients once or periodically [...]