Menée auprès de 118 participants, cette étude analyse la qualité des soins de support offerts aux patients atteints d'un cancer de stade avancé en phase terminale

The quality of supportive care among inpatients dying with advanced cancer

Walling, Anne ; Asch, Steven ; Lorenz, Karl ; Malin, Jennifer ; Roth, Carol ; Barry, Tod ; Wenger, Neil

Purpose Managing symptoms and communicating effectively are essential aspects of providing high-quality cancer care, especially among patients with advanced cancer. The purpose of this study is to apply novel quality indicators to measure the quality of supportive care provided to patients with advanced cancer who died in a large university medical center. Methods Cancer quality ASSIST is a comprehensive quality indicator (QI) set that includes 92 symptom and care planning indicators, of which [...]

Menée par entretiens individuels en population afro-américaine, cette étude analyse les aspects psychosociaux de la qualité de vie de survivants d'un cancer de la prostate et de leurs épouses

Understanding the Psychosocial Issues of African American Couples Surviving Prostate Cancer

Rivers, Brian ; August, Euna ; Quinn, Gwendolyn ; Gwede, Clement ; Pow-Sang, Julio ; Green, B. ; Jacobsen, Paul

African Americans are disproportionately affected by prostate cancer, yet less is known about the most salient psychosocial dimensions of quality of life. The purpose of this study was to explore the perceptions of African American prostate cancer survivors and their spouses of psychosocial issues related to quality of life. Twelve African American couples were recruited from a National Cancer Institute Comprehensive Cancer Center registry and a state-based non-profit organization to [...]

Menée auprès de 191 couples, cette étude analyse la prévalence des difficultés sexuelles, les modes de communication et les symptômes dépressifs chez des couples dont la femme est atteinte d'un cancer du sein métastatique

Sexual problems, communication patterns, and depressive symptoms in couples coping with metastatic breast cancer

Milbury, Kathrin ; Badr, Hoda

Background The treatment of breast cancer tends to result in physical side effects (e.g., vaginal dryness, stomatitis, and atrophy) that can cause sexual problems. Although studies of early-stage breast cancer have demonstrated that sexual problems are associated with increased depressive symptoms for both patients and their partners, comparatively little is known about these associations in metastatic breast cancer (MBC) and how patients and partners cope together with sexual problems. We [...]

Cette étude américaine analyse les difficultés sexuelles et la qualité de vie de survivantes homosexuelles d'un cancer du sein

Explanatory factors of sexual function in sexual minority women breast cancer survivors

Boehmer, U. ; Timm, A. ; Ozonoff, A. ; Potter, J.

Background: The sexual function of sexual minority women (women with female partners) who are breast cancer survivors is mostly unknown. Our objective is to identify explanatory factors of sexual function among sexual minority women with breast cancer and compare them with a control sample of sexual minority women without cancer.Patients and methods: Using a conceptual framework that has previously been applied to heterosexual breast cancer survivors, we assessed the relationship of each [...]

Menée sur 327 patients pédiatriques d'origine hispanique ou non et atteints d'une leucémie lymphoblastique aiguë, cette étude américaine identifie les facteurs d'adhésion à un traitement oral par la mercaptopurine et évalue, en fonction de l'appartenance ethnique des patients, l'effet d'une non adhésion au traitement sur le risque de récidive

Nonadherence to Oral Mercaptopurine and Risk of Relapse in Hispanic and Non-Hispanic White Children With Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group

Bhatia, Smita ; Landier, Wendy ; Shangguan, Muyun ; Hageman, Lindsey ; Schaible, Alexandra N. ; Carter, Andrea R. ; Hanby, Cara L. ; Leisenring, Wendy ; Yasui, Yutaka ; Kornegay, Nancy M. ; Mascarenhas, Leo ; Ritchey, A. Kim ; Casillas, Jacqueline N. ; Dickens, David S. ; Meza, Jane ; Carroll, William L. ; Relling, Mary V. ; Wong, F. Lennie

Purpose Systemic exposure to mercaptopurine (MP) is critical for durable remissions in children with acute lymphoblastic leukemia (ALL). Nonadherence to oral MP could increase relapse risk and also contribute to inferior outcome in Hispanics. This study identified determinants of adherence and described impact of adherence on relapse, both overall and by ethnicity.Patients and Methods A total of 327 children with ALL (169 Hispanic; 158 non-Hispanic white) participated. Medication [...]

Cette étude met à jour les données de l'Organisation Mondiale de la Santé relatives à la mortalité par leucémie en Europe sur la période 1970-2009 et présente des projections jusqu'en 2012

Trends in mortality from leukemia in europe: An update to 2009 and a projection to 2012

Bertuccio, Paola ; Bosetti, Cristina ; Malvezzi, Matteo ; Levi, Fabio ; Chatenoud, Liliane ; Negri, Eva ; La Vecchia, Carlo

We considered trends in mortality from leukemia in Europe over the period 1970-2009 using data from the World Health Organization. We computed age-standardized (world population) mortality rates, at all ages and in selected age groups, in 11 selected European countries, the European Union (EU), and, for comparative purposes, in the USA and Japan. For the EU, we also provided projections of the mortality to 2012. Over the period considered, mortality from leukemia steadily declined in most [...]

A partir des données du registre néerlandais du cancer, cette étude analyse l'évolution des traitements et de la survie des patients âgés atteints d'un cancer du poumon de stade précoce, sur la période 2001 à 2009

Early-stage lung cancer in elderly patients: A population-based study of changes in treatment patterns and survival in the Netherlands

Haasbeek, C. J. A. ; Palma, D. ; Visser, O. ; Lagerwaard, F. J. ; Slotman, B. ; Senan, S.

Background: Elderly patients with stage I non-small-cell lung cancer are less likely to undergo curative treatment. However, the introduction of new treatment options such as stereotactic ablative radiotherapy (SABR) may improve treatment rates. We evaluated time trends in treatment patterns and survival in the entire Netherlands population for patients diagnosed between 2001 and 2009.Patients and methods: Details of 4605 elderly Dutch patients were obtained from the Netherlands Cancer [...]

A partir des données des registres allemands du cancer, cette étude analyse l'évolution de la survie des patients atteints d'un cancer colorectal sur la période 2002-2006

Survival from colorectal cancer in Germany in the early 21st century

Majek, O. ; Gondos, A. ; Jansen, L. ; Emrich, K. ; Holleczek, B. ; Katalinic, A. ; Nennecke, A. ; Eberle, A. ; Brenner, H.

Colorectal cancer is the most common cancer in Germany and the second most common cause of cancer-related deaths in both men and women. The aim of this study is to provide detailed analysis of recent developments in survival of colorectal cancer patients using newly available data on a national basis. Methods: We included data from 11 German cancer registries covering a population of 33 million inhabitants. Period analysis and modelled period analysis were used to provide most up-to-date [...]

A partir des données de plusieurs registres du cancer de pays asiatiques, cette étude analyse l'évolution de l'incidence du cancer du sein et la mortalité en Mongolie sur la période 1998-2005 et la compare aux données chinoises, japonaises et russes

Breast cancer incidence in Mongolia

Troisi, Rebecca ; Altantsetseg, Dalkhjav ; Davaasambuu, Ganmaa ; Rich-Edwards, Janet ; Davaalkham, Dambadarjaa ; Tretli, Steinar ; Hoover, Robert ; Frazier, A.

Purpose Data on international variation in breast cancer incidence may help to identify additional risk factors. Substantially lower breast cancer rates in Asia than in North America and Western Europe are established, but differences within Asia have been largely ignored despite heterogeneity in lifestyles and environments. Mongolia’s breast cancer experience is of interest because of its shared genetics but vastly different diet compared with other parts of Asia. Methods Age-standardized [...]

Menée en Chine auprès de 24 041 femmes, cette étude en population analyse la prévalence de l'infection par le papillomavirus humain, en fonction du génotype, dans le cadre d'un dépistage du cancer du col de l'utérus

The prevalence and role of human papillomavirus genotypes in primary cervical screening in the northeast of China

Wang, Shizhuo ; Zhang, Shulan ; Heng, Wei ; Wang, Ning ; Zhang, Yao ; Ruan, Qiang ; Jiang, Weiguo ; Xiao, Qian ; Luan, Xiaomei ; Qian, Xiuyan ; Zhang, Lili ; Gao, Xiang ; Sun, Xiaowei

BACKGROUND:Studies have shown that type-specific persistence of high-risk human papillomavirus (HPV) infection contributed significantly to cervical carcinogenesis.METHODS:In this population-based study (on 24041 women)we report on the prevalent genotypes of HPVs and the prevalent genotypes of HPV persistent infection in the northeast of China.RESULTS:Our results showed that in HPV infected women (45.6% in total), (95% CI, 44.97%-46.23%), 17.35% (95%CI, 16.87%-17.83%) suffered persistent [...]

Menée sur 1 856 patients atteints d'un cancer oropharyngé associé ou non au papillomavirus humain et inclus dans deux essais de phase III évaluant une radiothérapie et une chimioradiothérapie, cette étude analyse le risque de progression de la maladie et de décès en fonction du statut p16 de la tumeur et du statut tabagique au diagnostic et durant le traitement

Tobacco Smoking and Increased Risk of Death and Progression for Patients With p16-Positive and p16-Negative Oropharyngeal Cancer

Gillison, Maura L. ; Zhang, Qiang ; Jordan, Richard ; Xiao, Weihong ; Westra, William H. ; Trotti, Andy ; Spencer, Sharon ; Harris, Jonathan ; Chung, Christine H. ; Ang, K. Kian

Purpose Tobacco smoking is associated with oropharynx cancer survival, but to what extent cancer progression or death increases with increasing tobacco exposure is unknown.Patients and methods Patients with oropharynx cancer enrolled onto a phase III trial of radiotherapy from 1991 to 1997 (Radiation Therapy Oncology Group [RTOG] 9003) or of chemoradiotherapy from 2002 to 2005 (RTOG 0129) were evaluated for tumor human papillomavirus status by a surrogate, p16 immunohistochemistry, and for [...]

Menée en Corée auprès de 2 661 patients atteints de cancer, cette étude transversale analyse leurs besoins psychosociaux en fonction de facteurs cliniques et sociodémographiques

Psychosocial needs of cancer patients and related factors: a multi-center, cross-sectional study in Korea

Choi, Kyung-Hyun ; Park, Jae-Hyun ; Park, Jong-Hyock ; Park, Joo-Sung

Background Identifying psychosocial needs and satisfying them are important issues to many cancer patients. The aim of this study was to investigate the psychosocial needs of cancer patients and its related factors, based on a nationwide sample of cancer patients in Korea. Methods A multi-center survey was administered to 2661 cancer patients from 10 cancer centers in Korea. The survey measured the needs for psychosocial support, using the Comprehensive Needs Assessment Tool in Cancer, and [...]

A partir de questionnaires auprès de 821 participantes, cette étude japonaise analyse la prévalence des difficultés et de la détresse psychologiques rencontrées par les épouses en deuil de leur conjoint décédé de cancer

Impaired mental health among the bereaved spouses of cancer patients

Asai, Mariko ; Akizuki, Nobuya ; Fujimori, Maiko ; Shimizu, Ken ; Ogawa, Asao ; Matsui, Yutaka ; Akechi, Tatsuo ; Itoh, Kuniaki ; Ikeda, Masafumi ; Hayashi, Ryuichi ; Kinoshita, Taira ; Ohtsu, Atsushi ; Nagai, Kanji ; Kinoshita, Hiroya ; Uchitomi, Yosuke

Objective Few cancer physicians routinely provide bereavement follow-up in clinical practice. The purpose of this study was to identify the prevalence of impaired mental health among the bereaved spouses over several years and explore the indicators for early detection of high-risk spouses during end-of life (EOL) care. Methods A cross-sectional mail survey was conducted for the bereaved spouses of patients who had died at the National Cancer Center Hospital of Japan. Bereaved spouses with [...]

Menée auprès de 740 participants australiens, cet essai de phase 3 évalue l'efficacité d'une intervention psychologique et pédagogique destinée à améliorer la qualité de vie et le bien-être physique et psychologique de patients nouvellement diagnostiqués avec un cancer de la prostate

Intervening to improve psychological outcomes for men with prostate cancer

Chambers, Suzanne K. ; Ferguson, Megan ; Gardiner, R. A. ; Aitken, Joanne ; Occhipinti, Stefano

Background Prostate cancer is the most common cancer in men in the Western world with well-described negative effects from treatments. However, outcomes are highly heterogeneous. A Phase 3 trial of a psycho-educational intervention was undertaken, aiming to reduce cancer-specific and decision-related distress and improve quality of life for men newly diagnosed with localised prostate cancer. Methods Seven hundred forty (81.7%) men were recruited after diagnosis and before treatment and [...]

Mené en Allemagne auprès de 186 patients atteints d'un cancer hématologique, cet essai randomisé analyse l'efficacité d'un programme d'aide et de soutien en ligne pour faire face à la maladie

Internet-based program for coping with cancer: a randomized controlled trial with hematologic cancer patients

David, N. ; Schlenker, P. ; Prudlo, U. ; Larbig, W.

Objective Psychosocial patient care in oncology is no longer limited to the inpatient setting. Outpatient services are in demand. Internet-based interventions could aid in optimizing service delivery across disciplines. The effectiveness of an Internet-based program for hematologic cancer patients was tested in a randomized controlled trial under field experimental conditions. Methods A 4-week cognitive-behavioral program for coping with cancer was offered to hematologic cancer patients online. [...]

Menée au Royaume-Uni par entretiens auprès de 2 018 participants, cette étude analyse les connaissances de la population relatives aux cancers du sein, du colon-rectum et du poumon, ainsi que leurs perceptions de la survie associée à ces divers cancers

Do the British public recognise differences in survival between three common cancers ?

Whitaker, K. L. ; Simon, A. E. ; Beeken, R. J. ; Wardle, J.

Background: The recognition that cancer is not a single entity, rather that different cancers have different causes and trajectories, has been a key development in the scientific understanding of cancer. However, little is known about the British public’s awareness of differences between cancers. This study examined differences in perceived survivability for three common cancers with widely disparate survival rates (breast, colorectal and lung). Method: In a population-based survey, using home [...]

Menée auprès de 136 participants, cette étude américaine évalue l'efficacité d'un programme d'éducation et d'informations relatives au cancer de la peau pour des malentendants

Evaluating a Skin Cancer Education Program for the Deaf Community

Harry, Kadie ; Malcarne, Vanessa ; Branz, Patricia ; Fager, Matthew ; Garcia, Barbara ; Sadler, Georgia

Skin cancer is the most common, preventable, and treatable cancer, so public education has been a priority. Unfortunately, for the Deaf community, most skin cancer information is difficult to access, so tailored approaches are needed. Participants ( N = 136) were randomly assigned to view either a skin cancer education video in American Sign Language ( n = 75) or an alternate video ( n = 61). All participants completed skin cancer knowledge questionnaires at baseline, immediately [...]

A partir des données du registre finlandais du cancer, cette étude analyse la pertinence du calcul de la survie relative pour estimer la survie brute dans une population de patients atteints d'un cancer du poumon

Should relative survival be used with lung cancer data ?

Hinchliffe, S. R. ; Rutherford, M. J. ; Crowther, M. J. ; Nelson, C. P. ; Lambert, P. C.

Background: Under certain assumptions, relative survival is a measure of net survival based on estimating the excess mortality in a study population when compared with the general population. Background mortality estimates are usually taken from national life tables that are broken down by age, sex and calendar year. A fundamental assumption of relative survival methods is that if a patient did not have the disease of interest then their probability of survival would be comparable to that of [...]