Patterns and Disparities in Human Papillomavirus (HPV) Vaccine Uptake for Young Female Adolescents among US States: NIS-Teen (2008-2016)
Menée aux Etats-Unis à partir de données d'enquêtes réalisées sur la période 2008-2016 auprès de 86 705 adolescentes de 13 à 17 ans, cette étude analyse l'association entre des facteurs de disparités socio-démographiques et économiques et les taux de vaccination contre le papillomavirus humain chez les jeunes filles
Résumé en anglais
Background: Several studies have reported differential vaccine uptake outcomes that are associated with socio-demographic and socio-economic characteristics, as well as provider type. However, none has examined a trend over a multiple-year span. In this study, we utilize a longitudinal data-based approach to examine state-level human papillomavirus (HPV) vaccine trends and their influences over time.
Methods: We analyzed National Immunization Survey-Teen data (2008-2016) to estimate HPV vaccine initiation rate in young female adolescent ages 13-17 years old among U.S. States. We identified growth patterns using the latent class growth method and explored state-level characteristics, including socio-economic and socio-demographic attributes, and health legislation and policy related programs among patterns.
Results: We identified three growth patterns, which showed gradually increasing vaccination trends but different baseline HPV uptake rates (high, moderate, low). State within Pattern 1 (highest HPV vaccination rates) included the lowest percentage of families with incomes below federal poverty level, the highest percentage of bachelor's degree or higher, and the lowest number of uninsured, while states within Pattern 3 included families with socio-economic attributes along the opposite end of the spectrum.
Conclusions: Latent class growth models are an effective tool to be able to capture health disparities in heterogeneity among states in relation to HPV vaccine uptake trajectories.
Impact: These findings might lead to designing and implementing effective interventions and changes in policies and healthcare coverage to promote HPV vaccination uptake for states represented under the lowest trajectory pattern.
