Treatment of colorectal peritoneal metastases requires multidisciplinary efforts

A partir de données portant sur 10 553 patients inclus dans 14 essais de phase III entre 1997 et 2008 et atteints d'un cancer colorectal avec des métastases dans la région péritonéale, cette étude analyse la survie globale et la survie sans progression après une chimiothérapie de première ligne

Résumé en anglais

With 8–20% of patients developing peritoneal metastases from colorectal cancer, this metastatic site ranks second or third in terms of incidence after the liver and lungs. The diagnosis of peritoneal metastases from colorectal cancer is mostly made at a very advanced stage because of the lack of specific symptoms of peritoneal metastases, and the low sensitivity of diagnostic imaging. Therefore, most patients with peritoneal metastases receive systemic chemotherapy similar to that given to patients with extra-peritoneal metastases