Menée au Royaume-Uni par questionnaire auprès de 394 patients atteints de cancer, cette étude analyse leurs besoins en soins de support et en information en fonction de l'âge (inférieur ou supérieur à 65 ans)

The influence of life stage on supportive care and information needs in cancer patients: does older age matter?

Watson, Maggie ; Davolls, Sue ; Mohammed, Kabir ; Shepherd, Sarah

Purpose : The purpose of this study is to clarify the effect of older age, on supportive care needs, information satisfaction and service needs in the year following a cancer diagnosis. Methods : Primary or recurrent prostate, breast, lung or colorectal cancer patients (n = 394) were prospectively surveyed 3 and 9 months post-diagnosis using the Support Care Needs Survey (SCNS-LF59) and Information Satisfaction (ISQ) and Service Needs (SNQ) questionnaires. Two age groups were compared: ≥65 [...]

A partir d'une revue systématique de la littérature (28 études, 8 118 patients atteints d'un cancer localisé de la prostate), cette étude analyse les facteurs associés à leurs sentiments de regrets liés au traitement reçu

Why do patients regret their prostate cancer treatment? A systematic review of regret after treatment for localized prostate cancer

Christie, David R. H. ; Sharpley, Christopher F. ; Bitsika, Vicki

Objective : The aim of this study was to review regret following treatment for localized prostate cancer, including factors associated with higher levels of regret, regret after specific treatments and the use of interventions to modify the likelihood of regret. Methods : Online databases including Medline, CINAHL, EMBASE, EBSCO and PsycINFO were searched in June 2014, using the terms ‘prostate’ and ‘regret’ for publications written in English and appearing in print since the year 1997. Results [...]

Menée en Allemagne auprès de 52 survivantes d'un cancer du sein de stade 0-III, cette étude analyse la possibilité de suivre ou d'adapter les recommandations de l'"American College of Sports Medicine" concernant l' intensité de la pratique d'exercices physiques chez les adultes en bonne santé

Exercise training intensity prescription in breast cancer survivors: validity of current practice and specific recommendations

Scharhag-Rosenberger, Friederike ; Kuehl, Rea ; Klassen, Oliver ; Schommer, Kai ; Schmidt, MartinaE ; Ulrich, CorneliaM ; Wiskemann, Joachim ; Steindorf, Karen

Purpose : Cancer survivors are recommended to perform 150 min/week of moderate or 75 min/week of vigorous aerobic exercise, but it remains unclear how moderate and vigorous intensities can be prescribed. Therefore, it was investigated whether and how intensity prescriptions for healthy adults by the American College of Sports Medicine (ACSM) need to be adapted for breast cancer survivors. Methods : Fifty-two breast cancer survivors (stage 0–III, age 52 ± 9 years, BMI 25.4 ± 3.5 kg/m2) performed [...]

Menée aux Etats-Unis, cette étude de cohorte compare, entre les patients infectés par le VIH et les autres, l'évolution de la survie à différents types de cancer non classant sida (119 cas de lymphome hodgkinien, 148 cas de cancer anal, 2 200 cas de cancer de la prostate, 699 cas de cancer colorectal, 587 cas de cancer du poumon), sur la période 1996-2011

Survival Among HIV-Infected and HIV-Uninfected Individuals with Common Non-AIDS-Defining Cancers

Marcus, Julia L. ; Chao, Chun ; Leyden, Wendy A. ; Xu, Lanfang ; Yu, Jeanette ; Horberg, Michael A. ; Klein, Daniel ; Towner, William J. ; Quesenberry, Charles P. ; Abrams, Donald I. ; Silverberg, Michael J.

Background: Non-AIDS-defining cancers increasingly contribute to mortality among human immunodeficiency virus (HIV)-infected individuals. However, few studies have compared cancer prognosis by HIV status with adjustment for risk factors. Methods: We conducted a cohort study of HIV-infected and HIV-uninfected adults in Kaiser Permanente California during 1996-2011, following subjects diagnosed with Hodgkin lymphoma (HL) or anal, prostate, colorectal, or lung cancers. We used Kaplan-Meier curves [...]

A partir des données de la cohorte "St. Jude Lifetime Cohort Study" incluant 1 361 participants, cette étude analyse la pertinence de diverses mesures anthropométriques (indice de masse corporelle, indice de masse grasse, rapport tour de taille-hauteur, analyse de la composition corporelle par une méthode d'absorptiométrie biénergétique à rayons X) pour caractériser l'obésité chez des survivants d'un cancer pédiatrique (âge moyen : 32, 4 ans)

Validity of anthropometric measurements for characterizing obesity among adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort Study

Karlage, Robyn E. ; Wilson, Carmen L. ; Zhang, Nan ; Kaste, Sue ; Green, Daniel M. ; Armstrong, Gregory T. ; Robison, Leslie L. ; Chemaitilly, Wassim ; Srivastava, Deo Kumar ; Hudson, Melissa M. ; Ness, Kirsten K.

BACKGROUND Childhood cancer survivors (CCSs) are at risk for obesity. The purpose of this project was to determine which clinical measures of body composition are most accurate among CCSs in comparison with dual-energy x-ray absorptiometry (DXA). METHODS The agreement between the body mass index (BMI), skinfold percent body fat, and waist-to-height ratio (WHtR) and DXA was evaluated among 1361 CCSs (mean age, 32.4 ± 7.7 years) 10 or more years after the diagnosis. The sensitivity and [...]

Menée aux Etats-Unis à partir de données portant sur des patients âgés de 65 à 99 ans ( 2 359 patientes atteintes d'un cancer du sein et 27 161 témoins ; 2 686 patients atteints d'un cancer de la prostate et 21 014 témoins), cette étude analyse la prévalence de comorbidités et les prescriptions de médicaments psychotropes

Medical comorbidity and psychotropic medication fills in older adults with breast or prostate cancer

Jones, SaleneM W. ; Rosenberg, Dori ; Ludman, Evette ; Arterburn, David

Background : Previous research has shown that as people age, distress decreases despite an increase in prevalence of medical comorbidity. This could be due to increased use of psychotropic medications with comorbidity. We tested this hypothesis in older adults. Methods : Information from medical records of older adults (65 to 99 years of age) in the following groups was collected: women with breast cancer (n = 2359), women without any cancer diagnosis (n = 27,161), men with prostate cancer [...]

Menée au Danemark, cette étude évalue la prévalence de personnes ayant survécu à un cancer, sur la période 1943-2010, et analyse leur satut socioéconomique ainsi que la prévalence de leurs comorbidités

Who are the cancer survivors? A nationwide study in Denmark, 1943-2010

Hovaldt, H. B. ; Suppli, N. P. ; Olsen, M. H. ; Steding-Jessen, M. ; Hansen, D. G. ; Moller, H. ; Johansen, C. ; Dalton, S. O.

Background : No nationwide studies on social position and prevalence of comorbidity among cancer survivors exist. Methods: We performed a nationwide prevalence study defining persons diagnosed with cancer 1943–2010 and alive on the census date 1 January 2011 as cancer survivors. Comorbidity was compared by social position with the non-cancer population. Results: Cancer survivors composed 4% of the Danish population. Somatic comorbidity was more likely among survivors (OR 1.59, 95% CI 1.57–1.60) [...]

A partir des données d'un registre japonais des cancers, cette étude analyse l'évolution des traitements et de la survie des patients atteints d'un lymphome ou d'un myélome, sur la période 1993-2006

Advance and stagnation in the treatment of patients with lymphoma and myeloma: Analysis using population-based cancer registry data in Japan from 1993 to 2006

Chihara, Dai ; Ito, Hidemi ; Izutsu, Koji ; Hattori, Masakazu ; Nishino, Yoshikazu ; Ioka, Akiko ; Matsuda, Tomohiro ; Ito, Yuri

There have been significant advances in the treatment of patients with lymphoma and myeloma. Although the improvements in survival outcome have been clearly addressed by clinical trials, these studies includes patients who are otherwise healthy and would be eligible for trials that the actual improvement in survival in the general patient population over time is yet to be elucidated. Therefore, we reviewed the cancer-registry data of patients with lymphoma and myeloma in Japan from 1993 to 2006 [...]

A partir d'une revue systématique de la littérature publiée jusqu'en mars 2014 (25 études), cette étude analyse les disparités ethniques dans l'association entre une infection anale par le papillomavirus humain et le risque de dysplasie et de cancer anal, chez des hommes homosexuels

Systematic Review of Racial Disparities in Human Papillomavirus–Associated Anal Dysplasia and Anal Cancer Among Men Who Have Sex With Men

Walsh, Tim ; Bertozzi-Villa, Clara ; Schneider, John A.

We systematically reviewed the literature on anal human papillomavirus (HPV) infection, dysplasia, and cancer among Black and White men who have sex with men (MSM) to determine if a racial disparity exists. We searched 4 databases for articles up to March 2014.Studies involving Black MSM are nearly absent from the literature. Of 25 eligible studies, 2 stratified by race and sexual behavior. Both reported an elevated rate of abnormal anal outcomes among Black MSM. White MSM had a 1.3 times lower [...]

Menée aux Etats-Unis auprès de 362 survivants à long terme d'un d'un neuroblastome diagnostiqué avant l'âge de 10 ans, cette étude analyse le risque d'ostéochondrome associé aux traitements

Osteochondroma in long-term survivors of high-risk neuroblastoma

Kushner, Brian H. ; Roberts, Stephen S. ; Friedman, Danielle N. ; Kuk, Deborah ; Ostrovnaya, Irina ; Modak, Shakeel ; Kramer, Kim ; Basu, Ellen M. ; Cheung, Nai-Kong V.

BACKGROUND Osteochondromas are benign bony protrusions that can be spontaneous or associated with radiotherapy (RT). Current treatment of high-risk neuroblastoma includes dose-intensive chemotherapy, local RT, an anti-GD2 monoclonal antibody (MoAb), and isotretinoin. Late effects are emerging. METHODS The authors examined osteochondromas in 362 patients who were aged <10 years when diagnosed with neuroblastoma, had received a MoAb plus isotretinoin since 2000, and had survived >24 months from [...]

Menée auprès d'une cohorte de 128 675 femmes ménopausées âgées de 50 à 79 ans et à partir des données de registres américains des cancers (durée moyenne de suivi : 11,5 ans), cette étude évalue, chez les patientes atteintes d'un cancer du sein, l'association entre l'utilisation de statines et le stade de la maladie au diagnostic ou la mortalité spécifique

Statins and breast cancer stage and mortality in the Women’s Health Initiative

Desai, Pinkal ; Lehman, Amy ; Chlebowski, RowanT ; Kwan, MarilynL ; Arun, Monica ; Manson, JoAnnE ; Lavasani, Sayeh ; Wasswertheil-Smoller, Sylvia ; Sarto, GloriaE ; LeBoff, Meryl ; Cauley, Jane ; Cote, Michele ; Beebe-Dimmer, Jennifer ; Jay, Allison ; Simon, MichaelS

Purpose : To evaluate the association between statins and breast cancer stage and mortality in the Women’s Health Initiative. Methods : The study population included 128,675 postmenopausal women aged 50–79 years, out of which there were 7,883 newly diagnosed cases of in situ (19 %), local (61 %)-, regional (19 %)- and distant (1 %)-stage breast cancer and 401 deaths due to breast cancer after an average of 11.5 (SD = 3.7) years of follow-up. Stage was coded using SEER criteria and was [...]

Menée au Royaume-Uni, cette étude analyse la faisabilité et l'efficacité d'une intervention psychosociale à base de coaching destinée aux survivants d'un cancer hématologique après une greffe de cellules souches hématopoïétiques

Life coaching following haematopoietic stem cell transplantation: a mixed-method investigation of feasibility and acceptability

Kenyon, M. ; Young, F. ; Mufti, G. J. ; Pagliuca, A. ; Lim, Z. ; Ream, E.

Haematopoietic stem cell transplantation (HSCT) cures many haematological cancers. Recovery post-HSCT is physically and psychologically challenging, lasting several months. Beyond the first post-transplant year, a fifth report difficulties encompassing practical, social and emotional domains, including finance and employment. We investigated the feasibility, acceptability and impact of a life coaching intervention designed to address psychosocial ‘survivor’ concerns of HSCT recipients and [...]

Mené en Suède auprès de 747 parents d'enfants traités pour un cancer, cet essai randomisé analyse la faisabilité et l'efficacité d'une intervention psychosociale sur internet destinée à les aider à prendre en charge leurs symptômes de stress postraumatique, de dépression et d'anxiété

Internet-based guided self-help for parents of children on cancer treatment: a randomized controlled trial

Cernvall, Martin ; Carlbring, Per ; Ljungman, Lisa ; Ljungman, Gustaf ; von Essen, Louise

Objective : The aim of the study was to investigate the feasibility and preliminary efficacy of an Internet-based guided self-help intervention for posttraumatic stress symptoms (PTSS) and related symptoms in parents of children on cancer treatment. Methods : Parents of children on cancer treatment, who fulfilled the modified symptom criteria on the PTSD Checklist, were randomly allocated to the intervention or to a wait-list control condition. The intervention group accessed a 10-week guided [...]

A partir des données de la cohorte "Women’s Health Initiative" incluant 6 949 patientes atteintes d'un cancer du sein et âgées de plus de 50 ans, cette étude analyse leurs symptômes de dépression et leur qualité de vie, avant et après le diagnostic de la maladie

Depression and quality of life before and after breast cancer diagnosis in older women from the Women’s Health Initiative

Jones, SaleneM W. ; LaCroix, AndreaZ ; Li, Wenjun ; Zaslavsky, Oleg ; Wassertheil-Smoller, Sylvia ; Weitlauf, Julie ; Brenes, GretchenA ; Nassir, Rami ; Ockene, JudithK ; Caire-Juvera, Graciela ; Danhauer, SuzanneC

Purpose : Distress and reduced quality of life (QOL) are common among people with cancer. No study has compared these variables after breast cancer diagnosis to pre-cancer diagnosis levels. Methods : Data on women with breast cancer 50 years of age or older (n = 6949) were analyzed from the Women’s Health Initiative (1993–2013). Health-related QOL (physical function, mental health) was measured using Rand-36. Depressive symptoms were measured with the six-item Center for Epidemiologic Studies [...]

Menée au Danemark, cette étude analyse la prévalence de déficiences cognitives et neuropsychologiques chez 72 survivants d'un cancer du testicule, 2 à 7 ans après les traitements anticancéreux

Cognitive impairment in testicular cancer survivors 2 to 7 years after treatment

Amidi, Ali ; Wu, LisaM ; Pedersen, AndersDegn ; Mehlsen, Mimi ; Pedersen, ChristinaGundgaard ; Rossen, Philip ; Agerbæk, Mads ; Zachariae, Robert

Purpose : The aim of the present study was to determine the prevalence of cognitive impairment (CI) in a group of testicular (TC) survivors by comparing their neuropsychological test scores with normative data and to assess their performance in specific cognitive domains. Methods : Seventy-two TC survivors were evaluated 2 to 7 years post-treatment with a neuropsychological test battery that assessed multiple cognitive domains—attention and working memory, processing speed, verbal fluency, [...]

A partir des données des registres américains des cancers portant sur 8 661 survivants d'un cancer diagnostiqué en 2004, cette étude rétrospective analyse le rôle des médecins généralistes et des spécialistes dans la prise en charge des comorbidités

Comorbid condition care quality in cancer survivors: role of primary care and specialty providers and care coordination

Snyder, ClaireF ; Frick, KevinD ; Herbert, RobertJ ; Blackford, AmandaL ; Neville, BridgetA ; Lemke, KlausW ; Carducci, MichaelA ; Wolff, AntonioC ; Earle, CraigC

Purpose : The purpose of this study is to investigate provider specialty, care coordination, and cancer survivors’ comorbid condition care. Methods : This retrospective cross-sectional Surveillance, Epidemiology, and End Results (SEER)-Medicare study included cancer survivors diagnosed in 2004, 2–3 years post-cancer diagnosis, in fee-for-service Medicare. We examined (1) provider specialties (primary care providers (PCPs), oncology specialists, other specialists) visited post-hospitalization, [...]

Menée au Royaume-Uni par enquête auprès de 460 professionnels de santé (infirmiers, médecins, chirurgiens), cette étude analyse leur rôle dans la promotion d'un mode de vie sain auprès de patients atteints de cancer

Health professionals' provision of lifestyle advice in the oncology context in the United Kingdom

Williams, K. ; Beeken, R. J. ; Fisher, A. ; Wardle, J.

A healthy lifestyle following a cancer diagnosis is linked with better long-term outcomes. Health professionals can play an important role in promoting healthy lifestyles after cancer, but little is known about the factors that influence whether or not they give lifestyle advice. We conducted an online survey to examine levels of, and predictors of, health professionals' provision of lifestyle advice to cancer patients in the United Kingdom. The survey included questions on awareness of [...]

A partir d'une revue systématique de la littérature publiée entre 1950 et 2013 (8 études), cette étude analyse l'association entre la capacité de compréhension de l'information médicale d'une personne et sa prise de décision éclairée relative au dépistage du cancer colorectal

Health literacy and informed decision making regarding colorectal cancer screening: a systematic review

Iris van der Heide ; Ellen Uiters ; A. Jantine Schuit ; Jany Rademakers ; Mirjam Fransen

Making an informed decision about participation in colorectal cancer (CRC) screening may be challenging for invitees with lower health literacy skills. The aim of this systematic review is to explore to what extent the level of a person’s health literacy is related to their informed decision making concerning CRC screening. We searched for peer-reviewed studies published between 1950 and May 2013 in MEDLINE, EMBASE, SciSearch and PsycINFO. Studies were included when health literacy was studied [...]

Menée aux Etats-Unis par enquête auprès de 2 311 participantes, cette étude analyse leurs connaissances relatives à l'impact de la densité mammaire sur la détection et le risque de cancer du sein

Awareness of Breast Density and Its Impact on Breast Cancer Detection and Risk

Rhodes, Deborah J. ; Radecki Breitkopf, Carmen ; Ziegenfuss, Jeanette Y. ; Jenkins, Sarah M. ; Vachon, Celine M.

Purpose : Legislation mandating disclosure of breast density (BD) information has passed in 21 states; however, actual awareness of BD and knowledge of its impact on breast cancer detection and risk are unknown. Methods : We conducted a national cross-sectional survey administered in English and Spanish using a probability-based sample of screening-age women, with oversampling of Connecticut, the only state with BD legislation in effect for > 1 year before the survey. Results : Of 2,311 women [...]

Menée aux Pays-Bas par questionnaire auprès de 6 263 professionnels en soins de support, cette étude analyse leur rôle et leur implication dans les soins dispensés au patient atteint de cancer durant le dernier mois de vie

Involvement of supportive care professionals in patient care in the last month of life

Brinkman-Stoppelenburg, Arianne ; Onwuteaka-Philipsen, BregjeD ; van der Heide, Agnes

Background : In the last month of life, many patients suffer from multiple symptoms and problems. Professional supportive care involvement may help to alleviate patients’ suffering and provide them with an optimal last phase of life. Purpose : We investigated how often palliative care consultants, pain specialists, psychological experts and spiritual caregivers are involved in caring for patients in the last month of life, and which factors are associated with their involvement. Methods : [...]

Menée aux Etats-Unis, cette étude évalue les objectifs et les actions mises en oeuvre dans le cadre de programmes dédiés à l'après-cancer dans un réseau de centres de lutte contre le cancer

An evaluation of cancer survivorship activities across national comprehensive cancer control programs

Underwood, J. Michael ; Lakhani, Naheed ; Rohan, Elizabeth ; Moore, Angela ; Stewart, SherriL

Introduction : Centers for Disease Control and Prevention’s (CDC) National Comprehensive Cancer Control Program (NCCCP) funds states, the District of Columbia, tribal organizations, territories, and jurisdictions across the USA develop and implement jurisdiction-specific comprehensive cancer control (CCC) plans. The objective of this study was to analyze NCCCP action plan data for incorporation and appropriateness of cancer survivorship-specific goals and objectives. Methods : In August 2013, [...]

A partir des données de sept registres italiens des cancers portant sur 636 patients atteints d'un mélanome cutané diagnostiqué entre 2003 et 2005, cette étude analyse l'adhésion aux recommandations internationales sur la déclaration et la description des caractéristiques de la pathologie cancéreuse

Population-based method for investigating adherence to international recommendations for pathology reporting of primary cutaneous melanoma: Results of a EUROCARE-5 high resolution study

Tumino, Rosario ; Minicozzi, Pamela ; Frasca, Graziella ; Allemani, Claudia ; Crocetti, Emanuele ; Ferretti, Stefano ; Giacomin, Adriano ; Natali, Maurilio ; Mangone, Lucia ; Falcini, Fabio ; Capocaccia, Riccardo ; Sant, Milena

Aim : Our study aim was to investigate the degree of adherence to international recommendations for cutaneous melanoma pathology reports at the population level by a EUROCARE high resolution study. Methods : The availability of nine characteristics – predominant cell type, tumour-infiltrating lymphocytes, mitotic index, histological subtype, growth phase, Clark level, Breslow thickness, ulceration, and sentinel-node biopsy – was examined on pathology reports of a random sample of 636 cases [...]