Low-Dose Radiation Associated Mortality Risks of Site-Specific Solid Tumors in U.S. Shipyard Workers
Menée auprès de 437 937 Américains ayant travaillé sur des chantiers navals nucléaires entre 1957 et 2004, cette étude analyse l'association entre une exposition professionnelle aux rayonnements et le risque de tumeur solide ainsi que la mortalité spécifique
Résumé en anglais
Background: U.S. nuclear capable shipyard workers have increased potential for occupational radiation exposure.
Objective: to examine solid tumor mortality risks at low doses.
Method: 437,937 workers working from 1957 to 2004 at eight U.S. shipyards were studied.
Results: Radiation workers with a median life-time dose at 0.82 mSv had a significantly lower solid tumor mortality risk [Relative risk (RR): 0.96, 95% confidence interval (CI): 0.94-0.98] than non-radiation workers. Among 153,930 radiation workers., the RRs of solid tumors increased with increasing dose categories without statistical significance. The dose category >0- < 25 mSv had significantly lower RR (0.95, 95% CI: 0.91-0.99) vs. 0 dose and the Excess Relative Risk was 0.05/100 mSv (95% CI: 0.01-0.08).
Conclusion: Solid tumor risk might increase with radiation dose, but not linearly at low doses. Actual mortality risk may be dependent on dose received.
