Opportunities for early detection of endometrial cancer in women with postmenopausal bleeding

A partir d'une revue systématique de la littérature publiée entre 1977 et 2017 (129 études, 40 790 femmes), cette méta-analyse évalue l'association entre des saignements après la ménopause et le risque de cancer de l'endomètre (34 432 souffrant de saignements, 6 358 cas de cancer)

Résumé en anglais

Endometrial cancer is the most common gynecologic malignancy and the fourth most common cancer among women in the United States.1 In 2018, there will be an estimated 63 230 women diagnosed with endometrial cancer.1 Currently, there is no effective endometrial cancer screening strategy for women who are asymptomatic. Fortunately, endometrial cancer is typically diagnosed in an early stage; 67% of women present with stage I or II disease confined to the uterus, at which point there is a 95% 5-year survival.2