Coming Full Circle—From Endless Complexity to Simplicity and Back Again

Cet article passe en revue l'évolution de la recherche sur les cancers depuis 40 ans et pointe ses oscillations entre une vision réductionniste et une vision prenant en compte la complexité des processus

Cell, Volume 157, Numéro 1, Page 267-271, 2014, article en libre accès

Résumé en anglais

Cell has celebrated the powers of reductionist molecular biology and its major successes for four decades. Those who have participated in cancer research during this period have witnessed wild fluctuations from times where endless inexplicable phenomenology reigned supreme to periods of reductionist triumphalism and, in recent years, to a move back to confronting the endless complexity of this disease.