Menée à partir de données 2006-2021 de la "UK Biobank" portant sur 347 591 personnes, cette étude analyse l'association entre la consommation d'alcool sans nourriture et le risque de cancer gastro-intestinal (6 813 cas) en fonction de l'âge au diagnostic (avant ou après 55 ans)

Alcohol Drinking Without Meals Is Associated with Risk of Gastrointestinal Cancers, Including Early-Onset Cases

Shi, Mengyao ; Ahmedin, Nadia J. ; Zong, Xiaoyu ; Yilmaz, Ӧmer H. ; Bishehsari, Faraz ; Cao, Yin

Globally, gastrointestinal (GI) cancers account for about 27% of newly diagnosed cancer cases and 37% of cancer deaths.1 Intriguingly, there has been an upward trend in the incidence of several GI cancers (gastric noncardia, pancreatic, and colorectal cancer) among adults younger than 50 or 55 years over the past several decades. Alcohol drinking, a pervasive behavior across the globe and a causal risk factor for esophageal squamous cell carcinoma, liver cancer, and colorectal cancer, is also [...]

Menée à partir de données d'une étude européenne portant sur 143 témoins et 143 patients atteints d'un cancer colorectal et ayant survécu à un cancer pédiatrique, cette étude estime le risque absolu de développer un cancer colorectal associé au traitement par radiothérapie

Cumulative Absolute Risk of Subsequent Colorectal Cancer After Abdominopelvic Radiotherapy Among Childhood Cancer Survivors: A PanCareSurFup Study

Emma J. Heymer ; Katarzyna Jóźwiak ; Leontien C. Kremer ; David L. Winter ; Florent de Vathaire ; Ceren Sunguc ; Elaine Sugden ; Judith L. Kok ; Helena J.H. van der Pal ; Lars Hjorth ; Zsuzsanna Jakab ; Milena M. Maule ; Riccardo Haupt ; Francesca Bagnasco ; Monica Terenziani ; Ibrahima Diallo ; Maria W. Gunnes ; Grit Sommer ; Lorna Zadravec Zaletel ; Claudia E. Kuehni ; Jeanette F. Winther ; Päivi M. Lähteenmäki ; Thorgerdur Gudmundsdottir ; Rodrigue S. Allodji ; Roderick Skinner ; Cécile M. Ronckers ; Michael M. Hawkins ; Raoul C. Reulen ; Jop C. Teepen

PURPOSE: Childhood cancer survivors are at the risk of developing subsequent colorectal cancers (CRCs), but the absolute risks by treatment modality are uncertain. We quantified the absolute risks by radiotherapy treatment characteristics using clinically accessible data from a Pan-European wide case-control study nested within a large cohort of childhood cancer survivors: the PanCareSurFup Study. METHODS: Odds ratios (ORs) from a case-control study comprising 143 CRC cases and 143 controls [...]

A partir d'une revue systématique de la littérature publiée jusqu'en mai 2023, cette méta-analyse évalue l'association entre une utilisation d'opium et le risque de cancer de la tête et du cou

Risk of head and neck cancer among opium users

Mohebbi, E. ; Alimoradi, Z. ; Rozek, L. S. ; Mohebbi, A. ; Jafari, E.

OBJECTIVE: The scientific literature presents conflicting data on a possible causal relationship between opium users and the development of head and neck cancer (HNC). This study aimed to explore the risk of HNC among opium users is a narcotic addictive drug. DESIGN: A systematic review and meta-analysis encompassed academic databases and gray literature up to May 2023, focusing on epidemiologic observational studies that reported the effect size of the HNC risk and opium use. RESULTS: This [...]