Leveraging Existing Pediatric Cancer Data through the Gabriella Miller Kids First Data Resource

Cet article décrit les données génétiques et cliniques mises à disposition par le "Kids First Data Resource Centre" (DRC) et le "Kids First Portal" sur les cancers pédiatriques ainsi que les malformations congénitales

Résumé en anglais

Childhood cancer and birth defects (BDs) are leading causes of childhood mortality, and studies suggest that BDs increase pediatric cancer risk. The Gabriella Miller Kids First Pediatric Research Program (Kids First) seeks to alleviate these conditions by building an expansive resource of genetic and clinical data from pediatric cancer and BD patients and families. This article describes the data and support provided by the Kids First Data Resource Center (DRC) and the Kids First Portal, which allows the public to review Kids First studies and request access to individual data. The Kids First Portal contains data from over 34,000 participants and connects with CAVATICA, a cloud-based analysis and sharing platform. Researchers have used Kids First data to investigate a variety of cancers and further funding opportunities are available. The Kids First Portal is a unique resource uniting pediatric cancer and BDs to uncover their genetic etiology and improve patient’s lives.