Breast cancer survivors with pain: an examination of the relationships between body mass index, physical activity, and symptom burden

Menée à partir de données portant sur 327 patientes ayant survécu à un cancer du sein, cette étude analyse l'association entre la pratique d'une activité physique, l'indice de masse corporelle et la sévérité des symptômes (douleur, fatigue, dépression)

Résumé en anglais

Purpose: Overweight and obesity are common for breast cancer survivors and associated with high symptom burden (i.e., pain, fatigue, depressive symptoms). Physical activity may protect breast cancer survivors with higher body mass indexes (BMI) from increased symptoms. However, the role of physical activity in buffering the relationship between higher BMI and greater symptoms is unclear.

Methods: Baseline data from a randomized trial investigating Pain Coping Skills Training among breast cancer survivors (N = 327) with pain were used to examine the relationship between self-reported BMI (kg/m2) and physical activity level (Rapid Assessment of Physical Activity; suboptimal vs. optimal) with pain (Brief Pain Inventory; severity and interference), fatigue (PROMIS-Fatigue short form), and depressive symptoms (Center for Epidemiological Studies Depression Scale). Analyses were conducted in SPSS. Hayes PROCESS macro (Model 1) assessed whether physical activity moderated the relationship between BMI and symptoms.

Results: Lower BMI (B = .06, p < .01) and optimal physical activity (B =