Global and regional estimates of genital human papillomavirus prevalence among men: a systematic review and meta-analysis

A partir d'une revue systématique publiée entre janvier 1995 et juin 2022 (65 études issues de 35 pays), cette méta-analyse estime pour 5 régions du monde (Afrique sub-saharienne, Amérique latine et Caraïbes, Amérique du Nord, Asie de l'Est et du Sud-Est, Europe) la prévalence chez les hommes d'une infection génitale par le papillomavirus humain

Résumé en anglais

Background : The epidemiology of human papillomavirus (HPV) in women has been well documented. Less is known about the epidemiology of HPV in men. We aim to provide updated global and regional pooled overall, type-specific, and age-specific prevalence estimates of genital HPV infection in men.

Methods : We conducted a systematic review and meta-analysis to assess the prevalence of genital HPV infection in the general male population. We searched Embase, Ovid MEDLINE, and the Global Index Medicus for studies published between Jan 1, 1995, and June 1, 2022. Inclusion criteria were population-based surveys in men aged 15 years or older or HPV prevalence studies with a sample size of at least 50 men with no HPV-related pathology or known risk factors for HPV infection that collected samples from anogenital sites and used PCR or hybrid capture 2 techniques for HPV DNA detection. Exclusion criteria were studies conducted among populations at increased risk of HPV infection, exclusively conducted among circumcised men, and based on urine or semen samples. We screened identified reports and extracted summary-level data from those that were eligible. Data were extracted by two researchers independently and reviewed by a third, and discrepancies were resolved by consensus. We extracted only data on mucosal