Mené auprès de 71 jeunes patients atteints d'un cancer (âge : 13-30 ans), cette étude évalue l'intérêt, pour améliorer leur qualité de vie et soulager leur fatigue, d'un programme d'exercices physiques dispensé en ligne

Evaluation of the MOVE online exercise programme for young people aged 13–30

Barnes, Ellie ; Hillier-Moses, Gemma ; Murray, Helen ; Stevinson, Clare ; Franks, Hester A. ; Gossage, Lucy

Purpose: To evaluate the MOVE exercise programme in supporting the recovery of young people affected by cancer. Methods: Participants in an 8-week exercise rehabilitation programme delivered online by cancer rehabilitation specialists completed self-reported questionnaires at baseline and after programme completion. Assessments included cancer-related fatigue (FACIT fatigue scale) and health-related quality of life (EORTC-QLC-30). Qualitative data were provided through written accounts of [...]

A partir d'une revue de la littérature (56 articles incluant un total de 8 554 aidants), cette méta-analyse évalue l'intérêt d'interventions pour améliorer la qualité de vie physique et psychique des aidants de patients atteints d'un cancer de stade avancé

Interventions to Improve Outcomes for Caregivers of Patients with Advanced Cancer: a Meta-Analysis

Chow, Ronald ; Mathews, Jean J ; Cheng, Emily YiQin ; Lo, Samantha ; Wong, Joanne ; Alam, Sorayya ; Hannon, Breffni ; Rodin, Gary ; Nissim, Rinat ; Hales, Sarah ; Kavalieratos, Dio ; Quinn, Kieran L ; Tomlinson, George ; Zimmermann, Camilla

BACKGROUND: Family caregivers of patients with advanced cancer often have poor quality of life (QOL) and mental health. We examined the effectiveness of interventions offering support for caregivers of patients with advanced cancer on caregiver QOL and mental health outcomes. METHODS: We searched Ovid MEDLINE, EMBASE, Cochrane CENTRAL, and CINAHL databases from inception through 6/2021. Eligible studies reported on randomized controlled trials for adult caregivers of adult patients with [...]

Menée en Suisse auprès de 158 adultes ayant survécu à un cancer pédiatrique (âge médian : 33 ans), cette étude de cohorte prospective analyse la prévalence d'une fatigue liée au cancer et identifie les facteurs associés

Prevalence and factors associated with cancer-related fatigue in Swiss adult survivors of childhood cancer

Sláma, Tomáš ; Belle, Fabiën N. ; Strebel, Sven ; Christen, Salome ; Hägler-Laube, Eva ; Rössler, Jochen ; Kuehni, Claudia E. ; von der Weid, Nicolas X. ; Schindera, Christina

Purpose: Reported prevalence of cancer-related fatigue (CRF) among childhood cancer survivors (CCS) varies widely, and evidence on factors associated with CRF among CCS is limited. We aimed to investigate the prevalence of CRF and its associated factors among adult CCS in Switzerland. Methods: In a prospective cohort study, we invited adult CCS who survived at least 5 years since last cancer diagnosis, and were diagnosed when age 0–20 years and treated at Inselspital Bern between 1976 and 2015 [...]

A partir d'une revue systématique de la littérature publiée entre 2000 et 2020 (7 articles), cette étude identifie les interventions de soins de support pour prendre en charge les symptômes gastro-intestinaux des patients ayant survécu à un cancer colorectal

Supportive care interventions for managing gastrointestinal symptoms following treatment for colorectal cancer: a systematic review

Ju, Angela ; Wiltink, Lisette ; Walker, Jared ; White, Kate ; Rutherford, Claudia

Introduction: Colorectal cancer (CRC) is prevalent in the developed world, with unhealthy lifestyles and diet contributing to rising incidence. Advances in effective screening, diagnosis, and treatments have led to improved survival rates, but CRC survivors suffer poorer long-term gastrointestinal consequences than the general population. However, the current state of clinical practice around provision of health services and treatment options remains unclear. Purpose: We aimed to identify what [...]

Menée en France auprès de 2 680 patientes ayant survécu à un cancer du sein et auprès de témoins, cette étude de cohorte analyse la présence de dysfonctionnements sexuels en lien avec la maladie et les traitements anticancéreux

Prevalence of sexual dysfunction after breast cancer compared to controls, a study from CONSTANCES cohort

Mangiardi-Veltin, Manon ; Mullaert, Jimmy ; Coeuret-Pellicer, Mireille ; Goldberg, Marcel ; Zins, Marie ; Rouzier, Roman ; Hequet, Delphine ; Bonneau, Claire

Purpose: Sexuality, a substantial factor in quality of life, may be altered after breast cancer (BC) treatments as they intimately afflict femininity. This study aimed to assess the prevalence of sexual dysfunction in women with a history of BC and to compare it with women without a BC history. Methods: The French general epidemiological cohort CONSTANCES includes more than 200,000 adults. All inclusion questionnaires from CONSTANCES non-virgin adult female participants were analyzed. Women [...]

A partir d'une revue systématique de la littérature (11 études), cette étude analyse les besoins en information et en soutien psychologique des adolescents et jeunes adultes (âge : 11-21 ans) dont la mère est atteinte d'un cancer du sein

Adolescents' needs for information and psychosocial support during their mother's breast cancer trajectory: A systematic review

Søby, Anne Katrine Hartmann ; Moos, Caroline M. ; Andersen, Aida Hougaard ; Ravn, Sophie Lykkegaard ; Andersen, Christina Maar ; Roessler, Kirsten Kaya

Objective : Breast cancer is the most common cancer diagnosis among women. The acute crisis and uncertainty that often follow diagnosis put the family at risk of exhaustion and dysfunction. Adolescents have been identified as a particularly vulnerable group of relatives. To investigate how to prevent distress in this group, we systematically reviewed research on adolescents' (11–21 years) needs for information and psycho-social support during their mothers' breast cancer trajectory. Method : [...]

Mené sur 34 patients ayant survécu à une tumeur du système nerveux central (âge au diagnostic : 6-47 ans), cette étude analyse leur santé cardio-respiratoire et leur qualité de vie

Cardiorespiratory fitness and health-related quality of life in survivors of childhood central nervous system tumours

Keating, Rachael ; Curry, Sarah ; Hussey, Juliette

Purpose: We assessed cardiorespiratory fitness and health-related quality of life (HRQoL) in survivors of childhood central nervous system (CNS) tumours. Methods: Participants were recruited from the National Children’s Cancer Service in Children’s Health Ireland at Crumlin. Inclusion criteria included diagnosis of a primary CNS tumour, aged between 6 and 17 years, between 3 months and 5 years post completion of oncology treatment, independently mobile, and deemed clinically appropriate to [...]

Menée à partir des données des registres américains des cancers, cette étude actualise les données portant sur la prévalence d'antécédents de cancer chez les patients atteints d'un cancer diagnostiqué entre 2009 et 2013

An Updated Report on the Prevalence of Prior Cancer Among Persons Newly Diagnosed With Cancer in the Surveillance, Epidemiology, and End Results Program

Murphy, Caitlin C. ; Tortolero, Guillermo A. ; Gerber, David E. ; Pruitt, Sandi L.

The population of cancer survivors in the US continues to increase. Three authors of the present study reported in 2018 that 18.4% of adults newly diagnosed with cancer (2009-2013) survived a previous cancer and may therefore be excluded from cancer clinical trials. Many organizations have since recommended considering cancer survivors who are newly diagnosed with cancer for enrollment in trials. We provide an update on the prevalence of prior cancer, including differences by age, sex, and race [...]

Menée à partir des données 2000-2019 des registres américains des cancers, cette étude analyse l'évolution de l'incidence du lymphome de Burkitt et la survie globale associée

Incidence of Burkitt lymphoma in the United States during 2000 to 2019

Mburu, Waruiru ; Devesa, Susan S. ; Check, David ; Shiels, Meredith S. ; Mbulaiteye, Sam M.

Burkitt lymphoma (BL) is an aggressive B-cell lymphoma that occurs worldwide. A study of BL in the US National Cancer Institute's Surveillance, Epidemiology and End Results (SEER) program during 1973 to 2005 (n = 3043) revealed three age-specific incidence peaks of BL and rates that were rising. We studied BL cases diagnosed in SEER 22 during 2000 to 2019 (n = 11 626) to investigate age-specific BL incidence rates and temporal trends. The age-standardized BL incidence rate was 3.96/million [...]

Menée en Suède à partir de données 2006-2018 portant sur 4 851 patients atteints d'un cancer de l'oesophage (période de suivi : 8 404 personnes-années ; 4 072 décès pendant la durée de suivi), cette étude de cohorte analyse l'association entre la présence d'un diabète, une utilisation de metformine et la survie

Diabetes, metformin use and survival in esophageal cancer: a population-based cohort study

Wang, Qiao-Li ; Santoni, Giola ; Lagergren, Jesper

It is unclear how diabetes and metformin use is associated with survival of esophageal cancer.This population-based cohort study included new cases of esophageal cancer reported in Sweden from 2006-2018 with follow-up through 2019. Diabetes status and metformin use were analyzed in relation all-cause and disease-specific mortality using multivariable Cox regression. The hazard ratios (HR) with 95% confidence intervals (CI) were adjusted for age, sex, calendar year, obesity, comorbidity, and use [...]

Menée dans un contexte de vie réelle à partir de données portant sur 881 patientes atteintes d'un cancer du sein triple négatif et connaissant une récidive précoce après un traitement néoadjuvant/adjuvant à base d'anthracyclines et/ou de taxanes, cette étude de cohorte analyse la survie globale et la survie sans progression

Real-world clinical and survival outcomes of patients with early relapsed triple-negative breast cancer from the ESME national cohort

Grinda, T. ; Antoine, A. ; Jacot, W. ; Cottu, P. H. ; de La Motte Rouge, T. ; Frenel, J. S. ; Mailliez, A. ; Dalenc, F. ; Goncalves, A. ; Clatot, F. ; Mouret Reynier, M. A. ; Lévy, C. ; Ferrero, J. M. ; Desmoulins, I. ; Uwer, L. ; Petit, T. ; Jouannaud, C. ; Arnedos, M. ; Chevrot, M. ; Courtinard, C. ; Tredan, O. ; Brain, E. ; Pérol, D. ; Pistilli, B. ; Delaloge, S.

Background: Early metastatic relapse of triple-negative breast cancer (mTNBC) after anthracyclins and/or taxanes based (A/T) primary treatment represents a highly aggressive cancer situation requiring urgent characterization and handling. ESME-metastatic breast cancer (MBC) database, a multicenter, national, observational cohort (NCT03275311) provides recent data on this entity. Methods: All ESME patients diagnosed between 2008 and 2020 with mTNBC occurring as a relapse after a systemic [...]

A partir d'une revue systématique de la littérature publiée entre 1997 et 2022 (45 articles), cette méta-analyse évalue l'intérêt d'outils permettant d'analyser la peur de la récidive de la maladie chez les aidants de patients atteints d'un cancer puis examine l'association entre cette peur et des symptômes de dépression et d'anxiété

Caregiver fear of cancer recurrence: A systematic review and meta-analysis of quantitative studies

Webb, Kyra ; Sharpe, Louise ; Butow, Phyllis ; Dhillon, Haryana ; Zachariae, Robert ; Tauber, Nina Møller ; O’Toole, Mia Skytte ; Shaw, Joanne

Objective: Fear of cancer recurrence (FCR) is reported by both cancer survivors and caregivers however less is known about caregiver FCR. This study aimed to (a) conduct a meta-analysis to compare survivor and caregiver FCR levels; (b) examine the relationship between caregiver FCR and depression, and anxiety; (c) evaluate psychometric properties of caregiver FCR measures. Methods: CINAHL, Embase, PsychINFO and PubMed were searched for quantitative research examining caregiver FCR. Eligibility [...]

Menée aux Pays-Bas à partir de données portant sur 2 434 adolescents et jeunes adultes ayant survécu à un cancer et auprès de 9 736 témoins, cette étude analyse l'effet de la maladie sur leurs revenus

Financial outcomes of Adolescent and Young Adult cancer survivors: a longitudinal population-based registry study

Siebinga, Ties M ; Janssen, Silvie H M ; Boumans, Anke W ; van Eenbergen, Mies C ; Siflinger, Bettina ; van der Graaf, Winette T A ; Husson, Olga

Background: The patterns and determinants of long-term income among adolescent and young adult (AYA) cancer survivors, and the differences compared to peers, have not yet been fully explored. This study investigated the long-term effects of cancer on the income of AYA cancer survivors. Methods: The Netherlands Cancer Registry identified all AYA cancer patients (18-39 years) diagnosed in 2013 and alive 5 years post diagnosis. Clinical data of the selected AYA patients were linked to individual, [...]

Cette étude présente les recommandations de la "Society for Integrative Oncology" et de l'"American Society of Clinical Oncology" concernant les approches d'oncologie intégrative dans la prise en charge de la douleur des patients atteints d'un cancer et la gestion des disparités ethniques dans cette prise en charge

SIO-ASCO Guideline on Integrative Medicine for Cancer Pain Management: Implications for Racial/Ethnic Pain Disparities

Liou, Kevin T ; Ashare, Rebecca ; Worster, Brooke ; Jones, Katie F ; Yeager, Katherine A ; Acevedo, Amanda M ; Ferrer, Rebecca ; Meghani, Salimah H

Racial and ethnic disparities in pain management pose significant challenges to equitable cancer care delivery. These disparities are driven by complex interactions between patient-, provider-, and system-related factors that resist reductionistic solutions and require innovative, holistic approaches. On September 19, 2022, the Society for Integrative Oncology (SIO) and the American Society of Clinical Oncology (ASCO) published a joint guideline to provide evidence-based recommendations on [...]