Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
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Sommaire du n° 564 du 9 mai 2023
Qualité de vie, soins de support (1)
Menée au Japon sur 173 patients atteints d'un cancer de la tête et du cou, cette étude de cohorte prospective analyse l'intérêt d'une intervention menée par les pharmaciens hospitaliers pour aider les patients à prendre en charge une mucite buccale induite par la chimioradiothérapie
Hospital pharmacist interventions for the management of oral mucositis in patients with head and neck cancer receiving chemoradiotherapy: a multice...
Menée au Japon sur 173 patients atteints d'un cancer de la tête et du cou, cette étude de cohorte prospective analyse l'intérêt d'une intervention menée par les pharmaciens hospitaliers pour aider les patients à prendre en charge une mucite buccale induite par la chimioradiothérapie
Hospital pharmacist interventions for the management of oral mucositis in patients with head and neck cancer receiving chemoradiotherapy: a multicenter, prospective cohort study
Yoshida, Kensuke ; Watanabe, Shinichi ; Hoshino, Naoto ; Pak, Kyongsun ; Hidaka, Noriaki ; Konno, Noboru ; Nakai, Masaki ; Ando, Chinami ; Yabuki, Tsuyoshi ; Suzuki, Naoto ; Katsura, Kouji ; Tomihara, Kei ; Toyama, Akira
Purpose: Oral mucositis is a severe adverse event in patients with head and neck cancer (HNC) receiving chemotherapy and radiotherapy that may cause the termination of cancer treatment. In this study, we aimed to reveal the benefits of pharmacist interventions in oral health care for patients with HNC receiving concurrent chemoradiotherapy (CCRT). Methods: We conducted a multicenter, prospective cohort study on 173 patients from September 2019 to August 2022. We evaluated the association [...]
Observation (6)
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Humoral Response after SARS-CoV-2 Vaccination in Prostate Cancer Patients
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Humoral Response after SARS-CoV-2 Vaccination in Prostate Cancer Patients
Błaszczuk, Agata ; Sikora, Dominika ; Kiś, Jacek ; Stępień, Ewa ; Drop, Bartłomiej ; Polz-Dacewicz, Małgorzata
Cancer is an important public health problem. Prostate cancer is one of the most common cancers among men. In Poland, the incidence of this type of cancer is constantly growing. Considering the appearance of a new coronavirus in December 2019 (SARS-CoV-2) and the fact that oncology patients, including those with prostate cancer, are particularly vulnerable to infection, it is recommended to get vaccinated against COVID-19. In our study, we determined the level and prevalence of antibodies [...]
Women’s perception about the discovery of breast cancer amid the covid-19 pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Women’s perception about the discovery of breast cancer amid the covid-19 pandemic
Carvalho, Simone Meira ; Andrade, Camilla de Abrahão ; Ferreira, Mariana Barbosa Leite Sérgio ; de Souza, Karine Soriana Silva ; Grincenkov, Fabiane Rossi dos Santos
Background: Breast cancer is considered a health problem at a worldwide level. In Brazil, the South and Southeast regions have the highest mortality rates. Understanding how they dealt with the diagnostic of a stigmatized disease amid the COVID-19 pandemic and its potential repercussions, may enable healthcare professionals to of life. Thus, this study is aimed at understanding the perception of women about the discovery of breast cancer and the impact of the disease on their lives. Methods: A [...]
Impact of the COVID-19 pandemic on cancer patients in western Pennsylvania: rural–urban disparities
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Impact of the COVID-19 pandemic on cancer patients in western Pennsylvania: rural–urban disparities
Demanelis, Kathryn ; Rosenzweig, Margaret ; Robertson, Linda B. ; Low, Carissa A. ; Daniels, Shayla ; Abujaradeh, Hiba ; Simon, Beth ; Bovbjerg, Dana H. ; Diergaarde, Brenda
Purpose: Disparities in cancer care persist between patients living in rural versus urban areas. The COVID-19 pandemic may have impacted concerns related to care and personal health differently in rural cancer patients. Using survey data collected from cancer patients in western Pennsylvania, we examined pandemic-related distress, concerns related to cancer care, impact on personal health, and the extent to which these differed by urban–rural residence. Methods: Patients filled out an initial [...]
Humoral Immunity After COVID-19 Vaccination in Chronic Lymphocytic Leukemia and Other Indolent Lymphomas: A Single-Center Observational Study
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Humoral Immunity After COVID-19 Vaccination in Chronic Lymphocytic Leukemia and Other Indolent Lymphomas: A Single-Center Observational Study
Doukas, Peter G ; St. Pierre, Frederique ; Karmali, Reem ; Mi, Xinlei ; Boyer, Jennifer ; Nieves, Mariana ; Ison, Michael G ; Winter, Jane N ; Gordon, Leo I ; Ma, Shuo
Chronic lymphocytic leukemia (CLL) and other non-Hodgkin’s lymphomas (NHLs) lead to broad immunosuppression, conferring a greater risk for morbidity and mortality from SARS-CoV-2. Our study analyzed antibody (Ab) seropositivity from SARS-CoV-2 vaccination in patients with these cancers.In the final analysis, 240 patients were involved, and seropositivity was defined as a positive total or spike protein Ab.Seropositivity was 50% in CLL, 68% in WM, and 70% in the remaining NHLs. Moderna [...]
COVID-19 in Adult Patients with Hematological Malignancies - Lessons Learned after Three Years of Pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
COVID-19 in Adult Patients with Hematological Malignancies - Lessons Learned after Three Years of Pandemic
Hus, Iwona ; Szymczyk, Agnieszka ; Mańko, Joanna ; Drozd-Sokołowska, Joanna
The COVID-19 pandemic is undoubtedly the most difficult health challenge of the 21st century with more than 600 million laboratory-confirmed SARS-CoV-2 infections and over 6.5 million deaths worldwide. The coronavirus pandemic contributed to rapid development of mRNA vaccines, which, along with new antiviral drugs, have been the subject of extensive research for many decades. Nevertheless, elderly, multi-morbid and immunocompromised patients continue to face a more severe clinical course and a [...]
Describing and exploring physical activity experiences among adults with cancer during the COVID-19 pandemic: a mixed-methods survey study
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Describing and exploring physical activity experiences among adults with cancer during the COVID-19 pandemic: a mixed-methods survey study
Lesser, Iris ; Janzen, Anna ; Arshad, Nafeel ; Wurz, Amanda
Understanding if (and how) adults with cancer perceived their physical activity (PA) levels have changed (or not) since the COVID-19 pandemic and why this may have occurred is important. Given current gaps in knowledge, the purpose of this study was to explore PA experiences among adults with cancer amidst the COVID-19 pandemic. Individuals were eligible if they were currently ≥19?years of age, had been diagnosed with cancer ≥18?years of age, and were living in Canada. 113 adults affected by [...]
Projected long-term effects of colorectal cancer screening disruptions following the COVID-19 pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Projected long-term effects of colorectal cancer screening disruptions following the COVID-19 pandemic
Nascimento de Lima, Pedro ; van den Puttelaar, Rosita ; Hahn, Anne I. ; Harlass, Matthias ; Collier, Nicholson ; Ozik, Jonathan ; Zauber, Ann G. ; Lansdorp-Vogelaar, Iris ; Rutter, Carolyn M.
The aftermath of the initial phase of the COVID-19 pandemic may contribute to the widening of disparities in colorectal cancer (CRC) outcomes due to differential disruptions to CRC screening. This comparative microsimulation analysis uses two CISNET CRC models to simulate the impact of ongoing screening disruptions induced by the COVID-19 pandemic on long-term CRC outcomes. We evaluate three channels through which screening was disrupted: delays in screening, regimen switching, and screening [...]
Vaccination for seasonal influenza, pneumococcal infection and SARS-CoV-2 in patients with solid tumors: recommendations of the Associazione Italia...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Vaccination for seasonal influenza, pneumococcal infection and SARS-CoV-2 in patients with solid tumors: recommendations of the Associazione Italiana di Oncologia Medica (AIOM)
Pedrazzoli, P. ; Lasagna, A. ; Cassaniti, I. ; Piralla, A. ; Squeri, A. ; Bruno, R. ; Sacchi, P. ; Baldanti, F. ; Di Maio, M. ; Beretta, G. D. ; Cinieri, S. ; Silvestris, N.
Patients with cancer have a well-known and higher risk of vaccine-preventable diseases (VPDs). VPDs may cause severe complications in this setting due to immune system impairment, malnutrition and oncological treatments. Despite this evidence, vaccination rates are inadequate. The Italian Association of Medical Oncology [Associazione Italiana di Oncologia Medica (AIOM)] has been involved in vaccination awareness since 2014. Based on a careful review of the available data about the [...]
Bend but don't break: Experience of a diverse New York City lung cancer screening program during the first year of the COVID-19 pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Bend but don't break: Experience of a diverse New York City lung cancer screening program during the first year of the COVID-19 pandemic
Stahl, Maximilian C. ; Shamah, Steven ; Wattamwar, Kapil ; Furlani, Andrea C. ; Serrano, Maria ; Haramati, Linda B.
Rationale and objectives : The COVID-19 pandemic led to the national shutdown and subsequent reopening of cancer screening programs. Our diverse inner-city lung cancer screening program serves patients in the Bronx NY, which was severely affected by COVID-19, with the highest mortality in New York State in the spring of 2020. Staffing redeployment, quarantine protocols, increased safety measures, and changes in follow up resulted. The purpose of this study is to analyze the effect of the [...]
Updated Review of Major Cancer Risk Factors and Screening Test Use in the United States, with a Focus on Changes During the COVID-19 Pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Updated Review of Major Cancer Risk Factors and Screening Test Use in the United States, with a Focus on Changes During the COVID-19 Pandemic
Star, Jessica ; Bandi, Priti ; Nargis, Nigar ; Islami, Farhad ; Yabroff, K Robin ; Minihan, Adair K. ; Smith, Robert A. ; Jemal, Ahmedin
We present national and state representative prevalence estimates of modifiable cancer risk factors, preventive behaviors and services, and screening, with a focus on changes during the COVID-19 pandemic. Between 2019 and 2021, current smoking, physical inactivity, and heavy alcohol consumption declined, and human papillomavirus vaccination and stool testing for colorectal cancer screening uptake increased. In contrast, obesity prevalence increased, while fruit consumption and cervical cancer [...]
Menée aux Etats-Unis sur la période 2010-2020, cette étude analyse l'association entre le type de lieu de restauration accessible (épiceries, marchés fermiers, restauration rapide) et la mortalité par cancer lié à l'obésité
Association of Food Deserts and Food Swamps With Obesity-Related Cancer Mortality in the US
Menée aux Etats-Unis sur la période 2010-2020, cette étude analyse l'association entre le type de lieu de restauration accessible (épiceries, marchés fermiers, restauration rapide) et la mortalité par cancer lié à l'obésité
Association of Food Deserts and Food Swamps With Obesity-Related Cancer Mortality in the US
Bevel, Malcolm Seth ; Tsai, Meng-Han ; Parham, April ; Andrzejak, Sydney Elizabeth ; Jones, Samantha ; Moore, Justin Xavier
Importance : Obesity-related cancers account for 40% of all cancers in the US. Healthy food consumption is a modifiable factor shown to reduce obesity-related cancer mortality, but residing in areas with less access to grocery stores (food deserts) or higher access to fast food (food swamps) reduces healthy food access and has been understudied. Objective : To analyze the association of food deserts and food swamps with obesity-related cancer mortality in the US. Design, Setting, and [...]
A Critical Need to Examine the Lack of Access to Healthy Quality Foods and Its Association With Cancer Mortality—A Clarion Call for Multilevel Rese...
Menée aux Etats-Unis sur la période 2010-2020, cette étude analyse l'association entre le type de lieu de restauration accessible (épiceries, marchés fermiers, restauration rapide) et la mortalité par cancer lié à l'obésité
A Critical Need to Examine the Lack of Access to Healthy Quality Foods and Its Association With Cancer Mortality—A Clarion Call for Multilevel Research and Interventions
Watson, Karriem S. ; Odoms-Young, Angela
Since the landmark review by Doll and Peto estimating the percentage of cancer deaths attributed to diet and other lifestyle factors more than 40 years ago, there has been a growing body of epidemiological and intervention research to identify and address modifiable risk factors associated with high rates of cancer morbidity and mortality in the US and globally. Yet, whereas historically, studies targeted individual-level drivers, evidence has shown that cancer outcomes are significantly [...]
Menée aux Etats-Unis à partir de données portant sur 3 806 patients ayant survécu à un cancer pédiatrique, cette étude de cohorte analyse l'association entre des caractéristiques du voisinage (niveau socio-économique, origine ethnique, zone rurale ou urbaine) et des fragilités
The Association of Neighborhood Characteristics and Frailty in Childhood Cancer Survivors: A Report from the St. Jude Lifetime Cohort Study
Menée aux Etats-Unis à partir de données portant sur 3 806 patients ayant survécu à un cancer pédiatrique, cette étude de cohorte analyse l'association entre des caractéristiques du voisinage (niveau socio-économique, origine ethnique, zone rurale ou urbaine) et des fragilités
The Association of Neighborhood Characteristics and Frailty in Childhood Cancer Survivors: A Report from the St. Jude Lifetime Cohort Study
Schwartz, Lindsay F. ; Dhaduk, Rikeenkumar ; Howell, Carrie R. ; Brinkman, Tara M. ; Ehrhardt, Matthew J. ; Delaney, Angela ; Srivastava, Deo Kumar ; Lanctot, Jennifer Q. ; Armstrong, Gregory T. ; Robison, Leslie L. ; Hudson, Melissa M. ; Ness, Kirsten K. ; Henderson, Tara O.
Background: Childhood cancer survivors experience reduced physiologic reserve, or frailty, earlier and more frequently than peers. In other populations, frailty is impacted by one's neighborhood. This study's purpose was to evaluate associations between neighborhood characteristics and frailty in childhood cancer survivors. Methods: Participants in the St. Jude Lifetime Cohort Study with geocoded residential addresses were analyzed. Pre-frailty/Frailty was defined as having 1–2/ [...]
Menée à partir de données 1990-2018 des registres américains des cancers, cette étude analyse l'effet de l'utilisation des inhibiteurs de tyrosine kinase sur l'évolution de l'incidence des leucémies lymphoblastiques et de la mortalité
The Impact of Improved Treatments on Survival of Adult U.S. Leukemia Patients: 1990–2018
Menée à partir de données 1990-2018 des registres américains des cancers, cette étude analyse l'effet de l'utilisation des inhibiteurs de tyrosine kinase sur l'évolution de l'incidence des leucémies lymphoblastiques et de la mortalité
The Impact of Improved Treatments on Survival of Adult U.S. Leukemia Patients: 1990–2018
Howlader, Nadia ; Sharon, Elad ; Bhattacharya, Manami ; Ehrlich, Lori A. ; Richardson, Nicholas C. ; Gormley, Nicole J. ; de Claro, R. Angelo ; Wood, Amy E. ; Mariotto, Angela B. ; Cronin, Kathleen A.
Introduction: Molecularly targeted therapies such as tyrosine kinase inhibitors (TKI) are effective treatments for B-cell receptor (BCR)-ABL–bearing leukemias. We evaluated the impact of TKIs on historical chronic myeloid leukemia (CML) mortality trends compared with acute lymphoblastic leukemia (ALL) and chronic lymphoblastic leukemia (CLL). Methods: Because mortality trends reflect combined effects of leukemia incidence and survival, we also evaluated the contribution of incidence and [...]
Menée à partir de données portant sur 137 patients atteints d'un cancer métastatique de la prostate résistant à la castration et recevant du docétaxel, cette étude de cohorte rétrospective analyse l'incidence d'une neutropénie (fébrile ou non) puis identifie les facteurs associés
Incidence, predictors, and outcomes of febrile neutropenia and neutropenia in patients with metastatic castrate-resistant prostate cancer receiving...
Menée à partir de données portant sur 137 patients atteints d'un cancer métastatique de la prostate résistant à la castration et recevant du docétaxel, cette étude de cohorte rétrospective analyse l'incidence d'une neutropénie (fébrile ou non) puis identifie les facteurs associés
Incidence, predictors, and outcomes of febrile neutropenia and neutropenia in patients with metastatic castrate-resistant prostate cancer receiving docetaxel
Peltekian, Sophie ; Sajwani, Shellyza ; Wang, Xiang ; Kanji, Salmaan
Purpose: The incidence of febrile neutropenia (FN) in adults with castrate-resistant metastatic prostate cancer (mCRPC) receiving docetaxel in real-world settings has not been well studied since the expanded role of hormonal treatments. The study objective was to determine the incidence of FN and neutropenia among adults with mCRPC receiving docetaxel. Secondary objectives were to quantify outcomes of patients who develop FN and to identify predictors for FN in this population. Methods: A [...]
Menée en Corée à partir de données 2002-2017 portant sur 55 228 patients âgés de plus de 65 ans et ayant survécu à un cancer colorectal diagnostiqué entre 2003 et 2012, cette étude de cohorte rétrospective analyse l'association entre une polypharmacie, la survenue d'événements indésirables entraînant des consultations d'urgence ou des hospitalisations et la mortalité toutes causes confondues
Association of polypharmacy with all-cause mortality and adverse events among elderly colorectal cancer survivors
Menée en Corée à partir de données 2002-2017 portant sur 55 228 patients âgés de plus de 65 ans et ayant survécu à un cancer colorectal diagnostiqué entre 2003 et 2012, cette étude de cohorte rétrospective analyse l'association entre une polypharmacie, la survenue d'événements indésirables entraînant des consultations d'urgence ou des hospitalisations et la mortalité toutes causes confondues
Association of polypharmacy with all-cause mortality and adverse events among elderly colorectal cancer survivors
Choi, Dong-Woo ; Kang, Hyejung ; Zhang, Hyun-Soo ; Jhang, Hoyol ; Jeong, Wonjeong ; Park, Sohee
Background: The risk of inappropriate drug exposure in elderly colorectal cancer (CRC) survivors after the initial cancer treatment has not been well studied. This study investigated the association of polypharmacy (PP) with overall survival, hospitalization, and emergency room (ER) visits among older CRC survivors. Methods: A retrospective cohort study was conducted using the Korean National Health Insurance claims data follow-up from 2002 to 2017. Participants comprised those aged ≥65 years [...]
Approches psycho-sociales (2)
Mené sur 71 patientes atteintes d'un cancer de stade métastatique (âge : 47-72 ans), cet essai randomisé évalue l'intérêt d'une intervention psycho-pédagogique dispensée pendant 6 semaines pour améliorer leur bien-être psychique et renforcer leur capacité de résilience
A 6-Week Program to Strengthen Resiliency Among Women With Metastatic Cancer: A Randomized Clinical Trial
Mené sur 71 patientes atteintes d'un cancer de stade métastatique (âge : 47-72 ans), cet essai randomisé évalue l'intérêt d'une intervention psycho-pédagogique dispensée pendant 6 semaines pour améliorer leur bien-être psychique et renforcer leur capacité de résilience
A 6-Week Program to Strengthen Resiliency Among Women With Metastatic Cancer: A Randomized Clinical Trial
Asher, Arash ; Shirazipour, Celina H ; Capaldi, Jessica M ; Kim, Sungjin ; Diniz, Marcio ; Jones, Bronwen ; Wertheimer, Jeffrey
Purpose: The objective of this study was to evaluate the effect of an intervention (Growing Resilience And CouragE; GRACE) on spiritual well-being, quality of life, and general well-being in women with metastatic cancers reporting existential or spiritual distress. Patients and Methods: Prospective, randomized, wait-list control clinical trial. Women with metastatic cancer experiencing existential or spiritual concerns were randomized to GRACE or waitlist control. Survey data were collected at [...]
Menée en Angleterre, cette étude analyse la participation au dépistage de masse du cancer du sein, du col utérin ou du côlon-rectum chez des personnes atteintes d'une maladie mentale sévère
Inequalities in cancer screening participation between adults with and without severe mental illness: results from a cross-sectional analysis of pr...
Menée en Angleterre, cette étude analyse la participation au dépistage de masse du cancer du sein, du col utérin ou du côlon-rectum chez des personnes atteintes d'une maladie mentale sévère
Inequalities in cancer screening participation between adults with and without severe mental illness: results from a cross-sectional analysis of primary care data on English Screening Programmes
Kerrison, Robert Stephen ; Jones, Alex ; Peng, Jianhe ; Price, Gabriele ; Verne, Julia ; Barley, Elizabeth Alexandra ; Lugton, Cam
Background: People with severe mental illness (SMI) are 2.5 times more likely to die prematurely from cancer in England. Lower participation in screening may be a contributing factor. Methods: Clinical Practice Research Datalink data for 1.71 million, 1.34 million and 2.50 million adults were assessed (using multivariate logistic regression) for possible associations between SMI and participation in bowel, breast and cervical screening, respectively. Results: Screening participation was lower [...]
Analyses économiques et systèmes de soins (1)
Menée en Angleterre à partir de données portant sur un total de 151 030 patients atteints d'un cancer du sein ou d'un cancer colorectal et traités par chirurgie entre 2016 et 2018, cette étude estime la "capacité chirurgicale" inutilisée dans le système hospitalier anglais
Managing the cancer backlog: a national population-based study of patient mobility, waiting times and "spare capacity" for cancer surgery
Menée en Angleterre à partir de données portant sur un total de 151 030 patients atteints d'un cancer du sein ou d'un cancer colorectal et traités par chirurgie entre 2016 et 2018, cette étude estime la "capacité chirurgicale" inutilisée dans le système hospitalier anglais
Managing the cancer backlog: a national population-based study of patient mobility, waiting times and "spare capacity" for cancer surgery
Aggarwal, Ajay ; Han, Lu ; Sullivan, Richard ; Haire, Kate ; Sangar, Vijay ; van der Meulen, Jan
Background: Waiting times for cancer treatments continue to increase in many countries. In this study we estimated potential ‘spare surgical capacity’ in the English NHS and identified regions more likely to have spare capacity based on patterns of patient mobility (the extent to which patients receive surgery at hospitals other than their nearest). Methods: We identified patients who had an elective breast or colorectal cancer surgical resection between January 2016 and December 2018. We [...]
Sensibilisation et communication (1)
A partir d'une revue systématique de la littérature publiée entre 1990 et 2020 (15 études), cette étude analyse la manière dont le risque de cancer héréditaire est abordé dans la famille auprès des enfants
Communication about hereditary cancer risk to offspring: A systematic review of children's perspective
A partir d'une revue systématique de la littérature publiée entre 1990 et 2020 (15 études), cette étude analyse la manière dont le risque de cancer héréditaire est abordé dans la famille auprès des enfants
Communication about hereditary cancer risk to offspring: A systematic review of children's perspective
Lima, Esperança ; Esplen, Mary Jane ; Martins, Filipa ; Alves, Marisa ; Sales, Célia M. D.
Objective: The present review describes how children experience hereditary cancer risk communication within the family. Methods: Searches for studies between 1990 and 2020 on PubMed and EBSCO were undertaken, and 15 studies met the inclusion criteria, following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The findings informed: (1) how, when and what is discussed about hereditary cancer risk in the family; (2) how does family communication about hereditary [...]