A partir d'une revue systématique de la littérature publiée jusqu'en juillet 2022 (5 études), cette méta-analyse évalue l'association entre une consommation d'édulcorants artificiels et le risque de cancer du sein

Association between Consumption of Artificial Sweeteners and Breast Cancer Risk: A Systematic Review and Meta-Analysis of Observational Studies

Ye, Xia ; Zhang, Yeyuan ; He, Yujing ; Sheng, Mingyuan ; Huang, Jianing ; Lou, Wenzhu

This study intends to conduct a meta-analysis based on existing research results to further investigate their relationship between artificial sweetener exposure and breast cancer risk. An electronic database literature search was performed up to July 2022, using PubMed, Web of Science, Ovid and Scopus. The relationship between artificial sweetener exposure and breast cancer (BC) incidence was evaluated by odds ratio (OR) and 95% confidence interval (CI). Among the five studies (two case-control [...]

A partir d'une revue systématique de la littérature publiée jusqu'en octobre 2022 (35 études), cette méta-analyse évalue l'association entre une consommation d'opium et le risque de cancer

The carcinogenicity of opium consumption: a systematic review and meta-analysis

M. Filho, Adalberto ; Turner, Michelle C. ; Warnakulasuriya, Saman ; Richardson, David B. ; Hosseini, Bayan ; Kamangar, Farin ; Pourshams, Akram ; Sewram, Vikash ; Cronin-Fenton, Deirdre ; Etemadi, Arash ; Glass, Deborah C. ; Rahimi-Movaghar, Afarin ; Sheikh, Mahdi ; Malekzadeh, Reza ; Schubauer-Berigan, Mary K.

The carcinogenicity of opium consumption was recently evaluated by a Working Group convened by the International Agency for Research on Cancer (IARC). We supplement the recent IARC evaluation by conducting an extended systematic review as well as a quantitative meta-analytic assessment of the role of opium consumption and risk for selected cancers, evaluating in detail various aspects of study quality on meta-analytic findings. We searched the published literature to identify all relevant [...]

A partir d'une revue systématique de la littérature (41 études), cette méta-analyse évalue le risque de cancer du sein chez les personnes transgenres

Risk and incidence of breast cancer in transgender individuals: a systematic review and meta-analysis

Corso, Giovanni ; Gandini, Sara ; D’Ecclesiis, Oriana ; Mazza, Manuelita ; Magnoni, Francesca ; Veronesi, Paolo ; Galimberti, Viviana ; La Vecchia, Carlo

Background and aims: The risk of developing breast cancer in transgender individuals [male-to-female (MtF) or female-to-male (FtM)] is still inadequately quantified. We aimed to evaluate the impact of breast cancer in this population. Methods: We conducted a systematic literature search and review using the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines through the PUBMED and SCOPUS databases. We identified six cohort studies (for both populations) plus 35 case [...]

Menée auprès de 834 témoins et 821 patientes afro-américaines atteintes d'un cancer du sein, cette étude analyse l'association entre 43 polymorphismes à simple nucléotide dans 20 gènes de la voie mTOR et des mesures d'obésité (indice de masse corporelle, tour de taille, rapport taille/hanche, répartition de la graisse corporelle) associées au risque de cancer du sein

mTOR pathway candidate genes and obesity interaction on breast cancer risk in black women from the Women’s Circle of Health Study

Ilozumba, Mmadili N. ; Yaghjyan, Lusine ; Datta, Susmita ; Zhao, Jinying ; Hong, Chi-Chen ; Lunetta, Kathryn L. ; Zirpoli, Gary ; Bandera, Elisa V. ; Palmer, Julie R. ; Yao, Song ; Ambrosone, Christine B. ; Cheng, Ting-Yuan David

Background: Obesity is known to stimulate the mammalian target of rapamycin (mTOR) signaling pathway and both obesity and the mTOR signaling pathway are implicated in breast carcinogenesis. We investigated potential gene-environment interactions between mTOR pathway genes and obesity in relation to breast cancer risk among Black women. Methods: The study included 1,655 Black women (821 incident breast cancer cases and 834 controls) from the Women’s Circle of Health Study (WCHS). Obesity [...]